Reference ranges for the fetal mitral, tricuspid, and interventricular septum annular plane systolic excursions (mitral annular plane systolic excursion, tricuspid annular plane systolic excursion, and septum annular plane systolic excursion) between 20 and 36 + 6 weeks of gestation

2020 ◽  
Vol 48 (6) ◽  
pp. 601-608
Author(s):  
Alberto Borges Peixoto ◽  
Nathalie Jeanne Bravo-valenzuela ◽  
Wellington P. Martins ◽  
Gabriele Tonni ◽  
Rosiane Mattar ◽  
...  

AbstractObjectivesThis study aimed to establish reference ranges for fetal mitral, tricuspid, and interventricular septum annular plane systolic excursions (MAPSE, TAPSE, and SAPSE) in normal pregnant women between 20 and 36 + 6 weeks of gestation.MethodsThis prospective and cross-sectional study included 360 low-risk singleton pregnancies between 20 and 36 + 6 weeks of gestation. MAPSE, TAPSE, and SAPSE were measured by M-mode in real time in an apical or basal four-chamber view through placing the cursor at the atrioventricular junction, marked by the valve rings at the tricuspid, mitral, and basal septum, respectively. A regression analysis was done to determine the appropriate polynomial equation model for both measurements and standard deviation (SD) values in relation to gestational age (GA). The intra- and inter-observer reproducibility was evaluated using the concordance correlation coefficient (CCC) and limits of agreement (LoA).ResultsThere was a significant positive correlation between MAPSE (r=0.705, p<0.0001), TAPSE (r=0.804, p<0.0001), and SAPSE (r=0.690, p<0.0001) and GA. The mean of each parameter ranged as follows: 2.87–5.56 mm, MAPSE; 3.98–8.07 mm, TAPSE; and 2.34–4.21 mm, SAPSE. Poor/moderate intra- and inter-observer reliability (CCC between 0.70 and 0.90) and poor/moderate agreement of all the tested parameters were evaluated (LoA between 10 and 50%).ConclusionsReference values were established for the fetal MAPSE, TAPSE, and SAPSE between 20 and 36 + 6 weeks of gestation in low-risk pregnant women. These parameters showed poor/moderate reproducibility.

2019 ◽  
Vol 21 (3) ◽  
pp. 279 ◽  
Author(s):  
Alberto Borges Peixoto ◽  
Nathalie Jeanne Bravo-valenzuela ◽  
Wellington P Martins ◽  
Rosiane Mattar ◽  
Antonio Fernandes Moron ◽  
...  

Aim: To establish reference range values for peak myocardial tissue Doppler velocity (MTD) and myocardial performance index (MPI) of the left ventricle (LV), the right ventricle (RV), and the interventricular septum (IVS) at 20 to 36+6 weeks of gestation using spectral tissue Doppler.Material and methods: This cross-sectional study was conducted among 360 lowrisk singleton pregnancies. MTD during systole (S’), and early (E’) and late diastole (A’), and MPI’ were assessed by placing sample volume at the basal segment of the LV free wall, the RV free wall, and the IVS, respectively. Polynomial regression was used to obtain the best-fit curves for MTD and MPI’ measurements as a function of gestational age (GA), and adjustments were made using the determination coefficient (R2). Intra- and inter-observer reproducibility was evaluated using the concordance correlation coefficient (CCC).Results: All MTD velocities (cm/s) progressively increased with advancing GA (p<0.0001). Mean LV MTD values were 4.19 to 6.86 for S’, 3.52 to 7.22 for E’, and 6.85 to 9.19 for A’; mean RV MTD were 4.85 to 7.97 for S’, 4.49 to 8.66 for E’, and 8.44 to 11.20 for A’; and mean IVS MTD values were 3.75 to 5.78 for S’, 3.34 to 5.79 for E’, and 5.88 to 7.98 for A’. LV MPI’, RV MPI’, and IVS MPI’ did not significantly change with advancing GA. The CCC values for MTD were predominantly greater than 0.70, while those for MPI’ were <0.70.Conclusions: Reference values for the fetal MTD and MPI’ of RV, LV and IVS using tissue Doppler between 20 and 36+6 weeks of gestation were described.


2019 ◽  
Vol 7 (4) ◽  
pp. 57
Author(s):  
Pati Aji Achdiat ◽  
Reiva Farah Dwiyana ◽  
Vina Feriza ◽  
Rasmia Rowawi ◽  
Rendy Ariezal Effendi ◽  
...  

About 81% of pregnant women with trichomoniasis are asymptomatic, while trichomoniasis in pregnant women can increase the risk of complications, include premature rupture of membranes, preterm birth, and babies with low birth weight. Trichomoniasis can also increase the risk of other sexually transmitted infections (STIs) and human immunodeficiency virus (HIV) transmission. Trichomoniasis case in pregnant women could be influenced by demographic characteristics,, the sexual behavior, and also the diagnostic method used. Until now, there is no data about prevalence of trichomoniasis in pregnant women in Indonesia. The aim of this research was to determine the prevalence of trichomoniasis in pregnant women in Bandung, West Java, Indonesia. A descriptive cross-sectional study was performed in December 2016 until January 2017. The study participants were 50 pregnant women who visit antenatal care to Obstetric and Gynecology Clinic of ’Rumah Sakit Khusus Ibu dan Anak Kota Bandung’, and meet the inclusion and exclusion criteria, through consecutive sampling. The study participants had a history taking, venereological examination, and Trichomonas rapid test from vaginal swabs. Trichomoniasis in this study was diagnosed based on Trichomonas rapid test, a test that uses color immunochromatographic, capillary flow, dipstick technology, and has high sensitivity and specificity in diagnosing trichomoniasis. Almost all participants in this study were low risk pregnant women to have STI based on demographic characteristics and sexual behaviour. The positive Trichomonas rapid test result was found from one of 50 study participants. In conclusion, prevalence of trichomoniasis in pregnant women in Bandung was 2%. Trichomoniasis case in low-risk pregnant women population is still found.


2014 ◽  
Vol 9 (1) ◽  
pp. 82-86
Author(s):  
K Subedi ◽  
D Chataut ◽  
UP Khanal ◽  
MA Ansari ◽  
S Pradhan

Aims: The purpose of this study was to study the feasibility of inclusion of 3-vessel view (3-VV) of the fetal upper mediastinum in routine fetal anomaly screening; and to study the size relationship of these vessels namely, main pulmonary artery (MPA), ascending aorta (AA) and the superior venacava (SVC) in fetuses between 17 and 24 weeks of pregnancy by antenatal ultrasound. Methods: This was a prospective cross sectional study involving 106 pregnant ladies between 17 and 24 weeks of gestation. The time burden to the examination due to addition of 3-VV in routine anomaly screening was recorded. The relationships of the three great vessels of the fetal upper mediastinum were studied and their diameters were obtained. Regression equations were used to construct the reference ranges for all the parameters of statistical significance. Results: The 3-VV could be easily obtained in all but eight patients within five minutes (the difficulty in these eight patients was due to fetal position). The MPA, AA and SVC were aligned in a straight line from left to right respectively, the MPA being the largest vessel, the SVC being the smallest vessel and the AA having an intermediate diameter. All of these three vessels showed significant correlation of size with advancing gestational age. Conclusions: 3-VV is easily obtained in fetuses at the time of routine anomaly screening. This should be routinely included in the screening ultrasound of fetal heart along with the four-chamber view to detect the anomalies of the outflow tract. DOI: http://dx.doi.org/10.3126/njog.v9i1.11197 NJOG 2014 Jan-Jun; 2(1):82-86


2011 ◽  
Vol 1 (1) ◽  
pp. 9 ◽  
Author(s):  
Yasuka Nakamura ◽  
Toyoko Yoshizawa ◽  
Fumi Atogami

Maternal psychosocial adaptation to pregnancy is significant task for women during pregnancy. Antepartum hospitalization is often characterized by maternal anxiety, boredom, feelings of imprisonment, and loneliness. The purpose of this study was to explore maternal psychosocial adaptation during pregnancy for hospitalized pregnant women compared with such adaptation in low-risk pregnant women from a reference population. This was a cross-sectional study with convenience samples of high-risk hospitalized and low-risk mothers. This study was carried out in five hospitals and two clinics between March and December 2009 in several areas of Japan. Subjects were 189 hospitalized women diagnosed with premature labor who had received continuous 24-h treatment with intravenous ritodrine hydrochloride for more than 1 week. The Japanese version of Prenatal Self-Evaluation Questionnaire was administered to measure maternal psychosocial adaptation during pregnancy. Women in hospitalized group had significantly lower adaptation in acceptance of pregnancy and preparation for labor (P&lt;.05-.001) and showed significantly higher adaptation in identification of a motherhood role and relationship with her husband. Moreover, in hospitalized group, relationship with her husband showed significantly higher adaptation (P&lt;.05) in primipara, acceptance of pregnancy and preparation for labor were significantly lower adaptation score (P&lt;.01-.001) in multipara. Hospitalized pre-term pregnant women should be assessed maternal psychosocial adaptation especially the domains of acceptance of pregnancy, preparation for labor, relationship with her husband, and identification of a motherhood role. Health care provider should know the character and background of those women as well as the character of primipara and multipara.


Author(s):  
Carolina Palmieri ◽  
Mona Simões ◽  
Jean Silva ◽  
Anelise Santos ◽  
Mariana Silva ◽  
...  

Objective To evaluate the prevalence of hypertrophic cardiomyopathy (HCM) in fetuses of pregnant women with gestational diabetes mellitus (GDM) in the beginning of the treatment. Methods A cross-sectional study was performed between July 1, 2013, and December 20, 2013, in a public maternity clinic in southern Brazil. The subjects were 63 fetuses of mothers with gestational diabetes, with a single pregnancy and no other associated pathologies. We diagnosed HCM through a fetal echocardiography before treatment and evaluated the maternal and fetal characteristics. Results The average age of the pregnant women was 32.32 (±6.2) years, and the average gestational age at the time of the evaluation was 30.59 (±2.27) weeks. The interventricular septum thickness showed a standard deviation of more than two in 50.8% of the fetuses (95% confidence interval [95%CI]: 38.1–63.5%). The left ventricular wall thickness showed a standard deviation of more than 2 in 13 (20.6%) fetuses (95%CI: 11.1–30.2%). The HCM was confirmed in 54% of the fetuses (95%CI: 41.3–65.1%). The fetal abdominal circumference was normal in 46 (73%) fetuses, and 50% of these fetuses had HCM. Conclusion The prevalence of hypertrophic cardiomyopathy in fetuses of pregnant women with GDM before treatment was of 54% (95%CI: 41.3–65.1%).


2005 ◽  
Vol 12 (4) ◽  
pp. 525-530 ◽  
Author(s):  
Olumuyiwa Aina ◽  
Jelpe Dadik ◽  
Manhattan Charurat ◽  
Patience Amangaman ◽  
Silas Gurumdi ◽  
...  

ABSTRACT A cross-sectional study that involved secondary analysis of data collected from 681 pregnant women and 183 miners (94 men and 89 women; ratio of men to women, 1:0.95) in Jos, Nigeria, was carried out to determine the reference ranges for CD4+-cell counts in healthy HIV-negative adult Nigerians. The main results of interest were CD4+-cell counts and odds ratios (ORs) of low CD4+-cell counts, defined as below 350 cells per μl. CD4+-cell counts were similar in men and nonpregnant women, with a mean (standard deviation) of 828 (203) cells per μl, but pregnant women had a lower value of 771 (250) cells per μl. None of the factors assessed was related to the odds of having a low CD4+-cell count among men and nonpregnant women, but age, age of marriage, and alcohol usage were significant predictors in pregnant women. Compared to pregnant women less than 20 years old, older women had significantly lower odds of a low CD4+-cell count (ORs were 0.06 for women aged 20 to 29 years and 0.22 for those aged 30 to 39 years). When compared with those pregnant women who were married before 20 years of age, those who married at 20 to 29 years and 30 to 39 years had odds ratios of 6.41 and 9.40, respectively. Previous alcohol use was also associated with low CD4+-cell counts (OR, 5.15). The 95% confidence interval for CD4+-cell counts in healthy adult Nigerians is 547 to 1,327 cells per μl, and this is the first time this has been determined.


2022 ◽  
Author(s):  
Carlos Izaias Sartorao Filho ◽  
Luiz Takano ◽  
Bruna Marcolino Paes Maria ◽  
Debora Giovanna Fernandes Vivaldo ◽  
Thais Sales Izidoro ◽  
...  

Background: Gestational Diabetes Mellitus (GDM) is a very prevalent disease and can cause several morbidities for women and their offspring. The literature demonstrates the necessity for a better approach during prenatal assistance to detect and treat the disease. We aimed to evaluate the model and efficacy of GDM screening and diagnosis in a referenced low-risk obstetrical center of the municipality of Assis, Sao Paulo state, Brazil. Moreover, the specific objective was to evaluate the prevalence of GDM. Methods: We conducted a retrospective cross-sectional study of pregnant women, in which 257 prenatal cards and the clinical approaches used for GDM diagnosis and their results. We observed the consecutive patients admitted to the low-risk referenced obstetrical service of the "Santa Casa de Assis-SP" for childbirth from January to August 2021. Results: There were 257 pregnant women, 227 prenatal cards obtained. Of these, 24.6% of the cards were considered incomplete, 25 (9.72%) did not contain the initial fasting plasma glucose information, and 93 (36.18%) did not describe this information in the second to the third trimester. The prevalence of GDM in the population was 14.78%. Conclusion: We observed many pregnant women not screened according to the recommended guidelines and many prenatal cards with incomplete information. According to the screening and diagnosis guidelines, GDM prevalence was underestimated. The lack of prenatal card information and inadequacy of screening and diagnoses were observed in this population.


2010 ◽  
Vol 18 (5) ◽  
pp. 919-927 ◽  
Author(s):  
Danielle Cristina Alves Feitosa Gondo ◽  
Marli Teresinha Cassamassimo Duarte ◽  
Márcia Guimarães da Silva ◽  
Cristina Maria Garcia de Lima Parada

This study identifies the prevalence of vaginal flora alterations in low-risk pregnant women and their association with reported symptoms and gynecological exams. This quantitative, descriptive, cross-sectional study was conducted in public primary care service units in Botucatu, SP, Brazil from 2006 to 2008 with 289 pregnant women from a stratified sample obtained by sampling by care unit. Tests of vaginal content were performed using Gram’s method and testing for Trichomonas vaginalis using Diamond’s medium. The prevalence of altered vaginal flora was 49.5%, of which bacterial vaginosis (20.7%), vaginal candidiasis (11.8%) and intermediate flora (11.1%) were the most frequent, not considering associations. Results revealed a high prevalence of vaginal flora alterations with little relation to symptoms, but in agreement with findings from the gynecological exams. Considering undesirable maternal and perinatal outcomes and feasible laboratory practices, the establishment of a routine for diagnosing vaginal flora alterations in low-risk pregnant women is suggested.


2021 ◽  
Vol 8 ◽  
Author(s):  
Fan Gao ◽  
Fanfan Guo ◽  
Yidan Zhang ◽  
Yufei Yuan ◽  
Dunjin Chen ◽  
...  

Background: Pregnancy-specific vitamin reference ranges are currently not available for maternal vitamin management during pregnancy. This study aimed to propose pregnancy-specific vitamin reference ranges and to investigate the factors influencing vitamin levels during pregnancy.Methods: A cross-sectional study that included pregnant women from 17 cities in 4 provinces in western China was conducted from 2017 to 2019. A total of 119,286 subjects were enrolled in the study. Serum vitamin A, vitamin D, and vitamin E levels were measured. A multivariable linear regression model and restricted cubic spline function were used to analyze the factors related to vitamin levels.Results: The reference ranges for vitamin A, D, and E levels were 0.22–0.62 mg/L, 5–43 ng/mL, and 7.4–23.5 mg/L, respectively. A linear relationship was found between vitamin E level and age (β = 0.004; 95% confidence interval [CI], 0.0037–0.0042; p &lt; 0.001), and a nonlinear relationship was found between vitamin D (p nonlinear = 0.033) and vitamin A levels and age (p nonlinear &lt; 0.001). Season, gestational trimester, and regions were related to the levels of the three vitamins in the multivariable models (p &lt; 0.05).Conclusions: The lower limit of vitamin A during pregnancy was the same as the reference value currently used for the general population. The reference ranges of vitamins D and E during pregnancy were lower and higher, respectively, than the currently used criteria for the general population. Vitamin A, D, and E levels differed according to age, season, gestational trimester, and region.


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