Colposcopical, cytological parallels in pregnant women with large intervals interhenetyc

2016 ◽  
pp. 77-81
Author(s):  
L.E. Tumanova ◽  
◽  
Е.V. Kolomiets ◽  
N.P. Badzyuk ◽  
◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Pregnant Women ◽  
Pap Smear ◽  
Precancerous Lesions ◽  
Statistical Processing ◽  
Antenatal Clinic ◽  
Cervix Uteri ◽  
Percentage Difference ◽  
First Time ◽  
Group 1

Relevance of the study of cervical pathology in pregnant women due not only to high frequency, the development of socially active women age and the ability to transition to the malignant form, but ineffective existing methods of diagnosis and treatment The objective: To investigate cytological, colposcopic features of cervical cancer in pregnant women with great interhenetyc interval. Patients and methods. We examined 81 women 40 women with great intergenetichnim intervals in the course of pregnancy, childbirth and the postpartum period – Group 1; 27 pregnant women who gave birth for the first time at the age of 30 years, 2-nd group, 14 pregnant women who have a break between the first and subsequent births was 3-5 years old – Group 3. The study of the cervix uteri of pregnant women with large intergenetic intervals in later stages performed by colposcopic and cytological methods. Statistical processing osuschstvlyali standard methods. Results. The data show elevated levels of precancerous cervical pathology in pregnant women with great interhenetyc intervals and in the age of pregnant women compared to young pregnant women in which the interval between births is small – 3–5 years. A small percentage difference precancerous lesions of the cervix, 22.5% – women in group 1 and 22.2% – women in group 2, but said that with increasing age probability themselves elimination papillomavirus is reduced accordingly increases the risk of precancer and cervical cancer. Conclusion. 1. The study showed that the problem of the status of the cervix in women with large intergenetic interval remains relevant and not studied until the end. 2. Pregnant women for the first time after 35 years and with more multiparous intergenetichnim interval must always be at the first visit to the antenatal clinic in addition to taking a Pap smear colposcopic spending review. 3. In case of LSIL and HSIL in this category of women – colposcopic and cytological control 1 every 3 months during pregnancy with mandatory HPV PCR WRC. Key words: cervical pathology, pregnancy, colposcopy, cytology.

scholarly journals Features of gestation, childbirth and the state of health of newborns in pre-pregnant women with chronic arterial hypertension

2021 ◽  
pp. 563-565
Author(s):  
Yuri A. Petrov ◽  
◽  
Igor V. Podgorny ◽  
Yulia Yu. Chebotaryova ◽  
Georgii I. Podgorny ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Arterial Hypertension ◽  
Pregnant Women ◽  
Postpartum Period ◽  
Statistical Processing ◽  
Newborn Health ◽  
Intrauterine Development ◽  
Birth Canal ◽  
First Time ◽  
Group 1

Aim. To analyze the features of the course of pregnancy, childbirth, the condition of newborns in pre-pregnant patients with hypertension. Materials and methods. 65 first-time pregnancies were examined, of which: group 1 (n=35) – first-time pregnancies with chronic arterial hypertension (O10.0 according to ICD X); group 2 (n=30) – first-time pregnancies with physiologically occurring pregnancy. The features of the anamnesis, the course of pregnancy, childbirth, the postpartum period, the condition of newborns were studied. Statistical processing was carried out using the program Statistica 6.0 for Windows. Results. It was revealed that the average age index (M±m) of women of the 1st group (38.6±0.22 years) was significantly higher than that of pregnant women of the 2nd group (26.6±0.22 years); p<0.0001. In women of group 1, pregnancy was complicated by a threatening abortion in the first and second trimesters (34.3 and 40%, respectively), 34.3% of fetuses had intrauterine development delay syndrome. Cesarean section was performed in 12 (34.3%) women of group 1. In group 1, during childbirth through the natural birth canal, in 13 (65.7%) after the birth of the fetus, the afterbirth separated independently in 11 (84.6%), in 2 (15.4%), manual separation and isolation of the afterbirth was performed. Conclusion. In pre-pregnant women with chronic arterial hypertension, pregnancy, childbirth and the postpartum period are complicated, with a high frequency of threatening abortion, cesarean section and increased blood loss in the postpartum period, low indicators of newborn health.

scholarly journals Prevalence of abnormal PAP smears in antenatal women in a tertiary hospital in India

2016 ◽  
Author(s):  
Saritha Shamsunder ◽  
Akriti Gautam ◽  
Geetika Khanna ◽  
Sunita Malik
Keyword(s):  
Pregnant Women ◽  
Pap Smear ◽  
Cervical Screening ◽  
Developed Countries ◽  
Antenatal Clinic ◽  
Comfort Level ◽  
Good Time ◽  
Pap Smears ◽  
Minor Bleeding ◽  
The Mean

Background: Pregnancy provides a good time for opportunistic screening of our women who rarely attend for cervical screening. The prevalence of abnormal PAP smear in pregnant women in developed countries was 5-6%, however, no literature was available from India. Aim: To determine the prevalence of abnormal PAP smears in antenatal women presenting to our antenatal clinic. Methods: Women attending the antenatal clinic with gestation of <28 weeks were recruited after an informed consent and had a PAP smear by Ayre spatula and cytobrush or a broom type of cytobrush. The comfort level during smear taking & any problems noted were recorded using a pain score. The smears were stained using the PAP stain, were categorized as adequate or inadequate & classified as per Bethesda classification. Results: We had 150 women participating, the mean age was 24.2 yrs, the mean period of gestation was 17 weeks; 43.9% were nulliparous. Smear adequacy rate was 71.5% overall. Pain during procedure was reported in 2.9% of women, 18.3% had minor discomfort; 78.6% were comfortable. Minor bleeding during smear taking was noted in 15%; this was more with the cytobrush & broom than the Ayre spatula alone. Abnormal smears were seen in three women; two had AGC & one had LSIL. Conclusions: Opportunistic cervical screening during pregnancy is safe and well tolerated. Abnormal Cervical smears were seen in 2% of our pregnant women.

scholarly journals Postpartum Pap Smear Results in Women with Abnormal Pap Smears Detected at First Antenatal Care: A Retrospective Study in a Songklanagarind Hospital

2021 ◽  
Vol 1 (2) ◽  
pp. 55-62
Author(s):  
Nungrutai Saeaib
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Cervical Cancer Screening ◽  
Pap Smear ◽  
Remission Rate ◽  
Pap Smears ◽  
Care Providers ◽  
Pregnancy And Postpartum

Objective: To assess the remission rate at postpartum periods of abnormal Pap smears during pregnancy, and to identify the demographic and clinical characteristics of pregnant women with abnormal Pap smears.Material and Methods: Pregnant women, who had antenatal care (ANC) in Songklanagarind Hospital in period of January 2011 to December 2019, were identified retrospectively. Exclusion criteria included inaccessible results of Pap smears during pregnancy and postpartum periods. Medical records of all pregnant women with abnormal Pap smears were reviewed. The association between Pap smear results during pregnancy and postpartum were analyzed by Cramer’s V statistic ranging from 0 to 1, with a 1 indicating perfect association.Results: Of these 8,238 pregnant women had available Pap smear results, 109 (1.3%) women were shown with abnormal results. The most common of abnormality from Pap smears were atypical squamous cells of undetermined significance. In postpartum period, 50 women who had abnormal Pap smear during pregnancy, underwent postpartum follow-up examination at six weeks postpartum, respectively. The majority of results (84.0%) were normal whilst rate of remission occurred in 45 women (90.0%). The association of Pap smears between during pregnancy and postpartum was shown to have a small association (Cramer’s V = 0.2).Conclusion: There was low prevalence of abnormal Pap smear during pregnancy and high remission rate at postpartum. However, health care providers should be aware of cervical cancer screening in all pregnant women, because many women had not undergone cervical cancer screening before pregnancy.

scholarly journals Classification and identification of human papillomavirus based on its prevalence and development of cervical lesion among Iranian women

Bioimpacts ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 235-242
Author(s):  
Mitra Moeinzadeh ◽  
Babak Kheirkhah ◽  
Kumarss Amini ◽  
Ali Pouryasin
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
Pap Smear ◽  
Precancerous Lesions ◽  
Single Type ◽  
Low Grade ◽  
Iranian Women ◽  
Cervical Lesions ◽  
Screening Programs ◽  
Hpv Genotyping

Introduction: Cervical cancer is the most common female cancer in large areas of the developing world, and almost half of these cases (54%) arises in Asia, where cervical cancer is still threatening women’s health and survival, which makes it a considerable public problem. Human papillomavirus (HPV) is one of the most powerful human carcinogens. Today, it has been proven that all cervical cancers and primary precancerous lesions are caused by carcinogenic types of HPV infections. HPV genotyping can therefore evaluate the screening programs. Methods: Five hundred fifty women referring to the gynecological centers were subjected to Pap smear cell samples. The cytopathological diagnosis of obtained cervical samples was based on the Bethesda system. HPV genotyping was carried out using the INNO-LiPA HPV Genotyping Extra II Amp assay. Results: In a total of 244 HPV positive cases, single‑type HPV infec­tion was observed in 49.6%, while multi‑type HPV infections (including ≥ 2 types) were found in 45.5% of cases. Among the 110 cases with abnormal cytology results, going-over analyses led to the identification of atypical squamous cell of unknown significance (ASCUS) in 73 cases, low‑grade squamous intraepithelial lesions (LSIL) in 24 cases, and high‑grade squamous intraepithelial lesion (HSIL) in 12 cases. In these groups, the infection rate of high-risk HPV (HR-HPV) was 89%, 82%, and 100%, respectively. Conclusion: In this study, the total population of women suffering from different cervical lesions and malignancy was found to be infected with various HPV genotypes. High prevalence of HPV- 53 and HPV- 16 detected among participants with normal cytology can be considered as a tip-off development of cervical cancer among Iranian women.

Early diagnosis program for cervical cancer in Tanzania: The “Vanda Project”.

2013 ◽  
Vol 31 (15_suppl) ◽  
pp. 5594-5594
Author(s):  
Patrizia Serra ◽  
Dino Amadori ◽  
Oriana Nanni ◽  
Alessandra Gennari ◽  
Sara Bravaccini ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Early Diagnosis ◽  
Pap Smear ◽  
Screening Program ◽  
Precancerous Lesions ◽  
Age Distribution ◽  
Sub Saharan Africa ◽  
High Risk Population ◽  
Lake Area ◽  
Breast Examination

5594 Background: In Sub-Saharan Africa cervical cancer represents 24% of all cancers and accounts for 23% of all cancer deaths in women. An early diagnosis program for breast and cervical cancer (Vanda Project) is ongoing in Mwanza and the surrounding lake area (12 districts with a population of 14,000,000). The aim of this project was to screen women aged 15-64 years living in the 12 districts. Methods: Women were invited to participate through local media and a mobile unit operating within the districts. A multidisciplinary team including medical oncologists was involved. Interventions consisted in Pap smear, clinical breast examination, breast self-examination training and training of district physicians to perform Pap smear and breast examination. Results: From May to December 2012, 2155 women from the districts of Shinyanga, Bukumbi, Kibara, Serengema and Musoma took part in the program: of these 91 (4%) had clinically evident cervical cancer. Age distribution classes were: < 18 years, 12% ; 18-35, 38%; 36-50, 41%; > 50, 9%. As expected a high stage distribution at diagnosis was observed: 30% stage III and 20% stage IV. Among the women with no clinical evidence of cancer, 408 samples were analyzed by cytology and 4% consisted of inadequate material. Of the remaining 392 samples, 85 (22%) were normal, 216 (55%) were infections (chiefly mycotic), 72 (18%) were precancerous lesions (50% H-SIL according to Bethesda classification) and 19 (5%) were positive for cancer (mainly stages III-IV). Precancerous lesions turned out to be cancer at histology in 44% of cases. 22% of precancerous lesions and 8% of clinically evident cancer were HIV-positive. Conclusions: This experience shows the high feasibility, good compliance and usefulness of a screening program for the early detection of cervical cancer in this high-risk population. [Table: see text]

scholarly journals Prevalence and associated risk factors of abnormal pap smear in pregnant women

2019 ◽  
Vol 8 (12) ◽  
pp. 4980
Author(s):  
Neha Mohindroo ◽  
Anoop Sharma ◽  
Santosh Minhas ◽  
Kushla Pathania
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
Bacterial Vaginosis ◽  
Pregnant Women ◽  
Pap Smear ◽  
Cervical Screening ◽  
Lower Class ◽  
Published Data ◽  
Papanicolaou Test ◽  
Associated Risk Factors

Background: The Papanicolaou test is a method of cervical screening used to detect pre-cancerous and cancerous processes. The incidence of cervical cancer in India is alarmingly high and is the leading cause of cancer in women in India accounting for 147 deaths per lakh women. Cervical cytological abnormalities are found in up to 5% of all pregnancies. In Indian settings, published data on abnormal Pap smear in pregnancy is lacking. The present study was designed to know the prevalence of abnormal Pap smear in pregnant women and its associated risk factors.Methods: This prospective study included 450 pregnant and 450 non-pregnant women who fulfilled the inclusion criteria. After a detailed history, clinical examination and investigations, Pap smear was collected as per conventional method and reported using 2014 Bethesda system.Results: 53.6% pregnant and 44.6% non-pregnant subjects had abnormal Pap smear. Out of the abnormal smears in pregnant women, 31.18% had inflammatory cytology, 15.37% had bacterial vaginosis, 4.01% had Trichomonal and 3.34% Monilial pathology. No epithelial cell abnormality was seen. Rural residence, lower class, age at first intercourse less than 21 years and having more than one sexual partner were important risk factors observed in our study and were statistically significant.Conclusions: Bacterial vaginosis, the most common infection detected on Pap smear is strongly associated with previos preterm labour and delivery. This opportunity for screening of cervical cancer and counselling should not be missed in the antenatal period.

Human Papillomavirus and Pap Smear

2011 ◽  
Vol 6 (1) ◽  
pp. 31-44
Author(s):  
Indra Balachandran
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
High Risk ◽  
Pap Smear ◽  
Precancerous Lesions ◽  
The United States ◽  
Hpv Infection ◽  
Hpv Testing ◽  
Pap Smear Screening ◽  
High Risk Hpv

High-risk human papillomavirus (HPV) infection and viral persistence is a major risk factor in the development of squamous intraepithelial lesions and invasive carcinoma of the cervix. In the United States, deaths due to squamous cell carcinoma of the cervix have fallen by 75% since the 1960s because of Papanicolaou (Pap) smear screening. However, the traditional Pap had a sensitivity of about 70% for detecting clinically significant precancerous lesions and cancer because of sampling and interpretive errors. The introduction of 2 liquid-based Pap smear collection systems in the 1990s, the use of HPV testing as a triage and co-testing with Pap smear, and the introduction of 2 automated screening devices have had a significant impact on improving the detection of such precancerous lesions. This review provides an analysis of the changes in Pap smear collection, improvements in screening, the evolutionary changes of high-risk HPV testing, reporting terminology of Pap smears, and clinical management guidelines. The future impact of 2 prophylactic HPV vaccines on the incidence of cervical carcinoma is also discussed. This article also discusses alternatives such as primary screening for high-risk HPV testing with visual inspection for cervical cancer detection used in resource-poor settings with a high incidence of cervical cancer.

scholarly journals Epidemiological Approach and Precocious Diagnosis of Precancerous Cervical Lesion in Sidi Bel Abbes Region (North-West of Algeria)

2020 ◽  
Vol 10 (1-s) ◽  
pp. 72-78
Author(s):  
Samira Meziani ◽  
Khadidja Haoud ◽  
Hayet Mehida ◽  
Norddine Menadi ◽  
Fatima Zohra Chenni ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Precancerous Lesions ◽  
Precancerous Lesion ◽  
Public Health Problem ◽  
Low Grade ◽  
High Grade ◽  
Squamous Intraepithelial Lesions ◽  
Pathology Laboratory ◽  
Intraepithelial Lesions

Object: Cervical cancer of the uterine (CCU) is the first cancer of the genital tract. In Algeria, this cancer remains a real public health problem. The diagnosis is still done often with advanced stages which makes the therapeutic results modest and the cost of the high care. Methodology: Our study aims to elucidate the reality of this type of pathology in the region of Sidi Bel Abbes, northwestern Algeria. This retrospective and descriptive study was devoted to the epidemiological and clinical analysis of cervical cancer cases over a period of 3 years. Results: This study shows that out of a total of 500 smears recorded between (2014-2016) at the Ana-pathology laboratory level in Sidi Bel Abbes, we found that 230 smears presented precancerous lesions according to a cytological study, atypical squamous cells of undetermined significance (ASC-US: were 18%; low-grade squamous intraepithelial lesions (LSIL) were 20%, while high-grade squamous intraepithelial lesions (HSIL) were 8%. The results obtained according to the distribution of the patients in relation to the various factors: the most affected age group is late 46-55 years with a total of 40%; precocious age of 1st report 18-20 years is (38.2%); gestation 4-5 pregnancies and parities 4-5 children with a rate of (38.70% and 32.6%) respectively ; the hormonal state in genital activity is estimated at 62.2%; patients on oral contraception (OC) have a rate of 48.9%. Finally, more than half of the patients (57.8%), were able to have a biopsy within three to four months of the last smear. In histology, the presence of a HPV (Human Papilloma Virus) low grade lesion does not predict the evolution of this lesion. Conclusion: HPV can be oncogenic or non-oncogenic. it is the oncogenic HPV infection that is the main risk factor for developing a high grade lesion  and cervical cancers outside the associated cofactors. Keywords: Pap Smear, Precancerous lesion, Cancer, Cervix, Screening

scholarly journals Colposcopic and cytological parallels in pregnant women with a history of infertility of various genesis

2021 ◽  
pp. 5-11
Author(s):  
Е.V. Kolomiiets ◽  
Keyword(s):  
Pregnant Women ◽  
Antenatal Clinic ◽  
The State ◽  
Group 4 ◽  
Cytological Smear ◽  
History Of ◽  
Group 3 ◽  
Cytological Changes ◽  
Group 2 ◽  
Group 1

The state of the cervix was studied in pregnant women with a history of infertility of various genesis by colposcopic and cytological research methods. The data obtained indicate an increased level of precancerous pathology of the cervix in pregnant women with a history of tubo-peritoneal and concomitant infertility, compared with pregnant women who had endocrine infertility. Purpose — to determine the relationship between the nature and severity of colpocoscopic and cytological changes in the cervix in pregnant women who had a history of infertility. Materials and methods. 101 women were examined: 14 pregnant women with a history of endocrine infertility, group 1; 27 pregnant women with a history of tuboperitoneal infertility — group 2; 40 pregnant women, had combined infertility — group 3, 20 healthy pregnant women with no history of infertility — group 4. Methods for assessing the state of the cervix in pregnant women — video colposcopic and cytological (on glass). Results. Normal cytological changes (NILM) were found: in group 1–8 (57.2%), in group 2 — in 15 (55.6%), in group 3 — in 23 (57.5%), in group 4, 14 (70.0%) pregnant women. Benign cytological and ASCUS signs were: in group 1 — in 5 (35.7%), in group 2 — in 6 (22.2%), in group 3 — in 10 (25.0%), in group 4 — in 5 (25%) patients. Precancer (LSIL+HSIL): in group 1 — in 1 (7.1%), in group 2 — in 6 (22.2%), in group III — in 9 (22.5%) women, and in group 4, no precancers were found cytologically. Normal colposcopic signs (stratified squamous epithelium) were found: in group 3 — in 11 (27.5%), in group 2 — in 8 (29.6%), and in group 1 — in 7 (50.0%) pregnant women. And benign colposcopic changes (ectopia, open glands, Nabotovi cysts, deciduosis): in group 3 — in 19 (47.5%), in group 2 — in 16 (59.3%), in group 1 — in 6 (42.9%), in group 4 — in 5 (35.7%) patients. Our data indicate that precancers during colposcopy occurred: in group 3 — in 9 (22.5%), in group 2 — in 3 (11.1%), in group 1 — in 1 (7.1%), in group 4 — in 1 (5.0%) women. No colposcopic signs of invasive growth were found in any of the groups. Conclusions. The study revealed an increased level of precancerous pathology of the cervix in pregnant women with a history of tubo-peritoneal and concomitant infertility. A fairly high percentage of precancerous conditions of the cervix in group 2 — in 6 (22.2%) and in group 3 — in 9 (22.5%) women indicates that in the presence of Human papillomavirus (HPV) and other genital infections and with increasing age, the probability self-elimination of the papilloma virus is reduced. After long-term infertility treatment, all pregnant women must undergo a colposcopic examination at the first visit to the antenatal clinic, in addition to taking a cytological smear. If LSIL and HSIL are found in this category of women, colposcopic and cytological control once every 3 months during pregnancy with mandatory HPV PCR HCR. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local ethics committee of all participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the author. Key words: pathology of the cervix, pregnancy after infertility, video colposcopy, cytology.

Awareness of cervical cancer and screening among rural Nepalese women.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 1553-1553 ◽  
Author(s):  
Anju Shrestha
Keyword(s):  
Cervical Cancer ◽  
Rural Community ◽  
Pap Smear ◽  
Precancerous Lesions ◽  
Pap Test ◽  
Population Based ◽  
Cancer Knowledge ◽  
Cross Sectional ◽  
Cancer Support ◽  
Pap Smear Screening

1553 Background: Cervical cancer is leading female cancer in Nepal. Despite the existence of effective screening using Pap smear, the uptake of screening is poor. Objectives of this study were to determine the baseline information about the knowledge of cervical cancer and explore attitude and practice of Pap smear screening among the women of rural community of Nepal. Methods: A cross sectional population based descriptive study of female attending free cervical cancer screening camp in different rural community of Nepal organized by Nepal cancer Support group and Nepal cancer Hospital, funded by Direct Relief was conducted from 1/06/2016 to 31/12/2016- using self- administered questionnaire to elicit information on demographic characteristics, knowledge, screening behaviors and determinants of cervical cancer. Results: A total of 2529 women participated in nine screening camp, out of which 55.95% (1416) were illiterate whereas only 4.95% (129) were graduate. Mean age of participates were 40.5±11.97 (17-83)yrs. 31.63% (800) of women married before age of 16 and 32.08% (811) women had their first childbirth before age of 18 years. Only 6.88% (174) women were working outside and rest were working in household work and farming. 76.24% (1928) women knew nothing about cervical cancer. Although 38.71% (979) women heard about Pap smear, only 10.36% (262) knew about eligibility of screening, 1.58% (40) knew about screening interval and 16.57% (419) know that Pap smear is used for detections of cancerous and precancerous lesions of cervix. However, knowledge of risk factors for cervical cancer was found in 5.9% (150). Of the female respondents, 78.09% (1975) did not feel susceptible to cervical cancer and 82.25% (2080) had never been screened before. The most common reason for not doing Pap test is they never heard about it (59.99%:1516). The other reason includes do not have any symptoms (17.79%:450); embarrassment (2.49%:62); do not know where to do (1.27%:32); fear of finding out cancer (0.51%:13) and never advised by doctor (0.4%:10). Conclusions: The study revealed very low cervical cancer knowledge and poor screening behavior among the women. This may be due to lack of awareness, education and low priority of women’s health issue.

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