scholarly journals Neuroaxis Block Compared to General Anesthesia for Revascularization of the Lower Limbs in the Elderly. A Systematic Review with Metanalysis of Randomized Clinical Studies

2009 ◽  
Vol 59 (2) ◽  
pp. 234-243
Author(s):  
Fabiano Timbó Barbosa ◽  
Mário Jorge Jucá ◽  
Aldemar Araújo Castro
2020 ◽  
Vol 24 (4) ◽  
pp. 29-36
Author(s):  
André Augusto Martines Teixeira Mendes ◽  
Hugo Jário de Almeida Silva ◽  
Ana Rafaella Araújo Costa ◽  
Yago Tavares Pinheiro ◽  
Caio Alano de Almeida Lins ◽  
...  

2021 ◽  
Vol 42 ◽  
pp. 281-311
Author(s):  
R Puts ◽  
◽  
L Vico ◽  
N Beilfuß ◽  
M Shaka ◽  
...  

Impaired bone-fracture healing is associated with long-term musculoskeletal disability, pain and psychological distress. Low-intensity pulsed ultrasound (LIPUS) is a non-invasive and side-effect-free treatment option for fresh, delayed- and non-union bone fractures, which has been used in patients since the early 1990s. Several clinical studies, however, have questioned the usefulness of the LIPUS treatment for the regeneration of long bones, including those with a compromised healing. This systematic review addresses the hurdles that the clinical application of LIPUS encounters. Low patient compliance might disguise the effects of the LIPUS therapy, as observed in several studies. Furthermore, large discrepancies in results, showing profound LIPUS effects in regeneration of small-animal bones in comparison to the clinical studies, could be caused by the suboptimal parameters of the clinical set-up. This raises the question of whether the so-called “acoustic dose” requires a thorough characterisation to reveal the mechanisms of the therapy. The adequate definition of the acoustic dose is especially important in the elderly population and patients with underlying medical conditions, where distinct biological signatures lead to a delayed regeneration. Non-industry-funded, randomised, double-blind, placebo-controlled clinical trials of the LIPUS application alone and as an adjuvant treatment for bones with complicated healing, where consistent control of patient compliance is ensured, are required.


2021 ◽  
Vol 9 (T5) ◽  
pp. 6-12
Author(s):  
Kadek Dio Agus Bagiartana ◽  
Titih Huriah

BACKGROUND: Balance disorders are the primary cause of falls, a significant health concern for the elderly. Tai Chi (TC) improves the balance and strength of the lower limb muscles that focus on centering the mind, bodywork, and breathing exercises. AIM: A systematic review was conducted to search for evidence of the effects of Thai Chi in balancing and strengthening of lower extremities among the elderly in the community. METHODS: According to the preferred reporting items for systematic reviews and meta-analyses guidelines, a systematic review was conducted. Databases included Science Direct, ProQuest, and PubMed, from 2015 to 2020, with research articles being original studies. The quality of research articles was assessed using the Physiotherapy Evidence Database scale. Systematically analyses were used for results syntheses. RESULTS: Six articles were included in this review. TC exercises effectively improve the balance and muscle strength of the lower limbs among the elderly in the community. TC has a beneficial effect on evaluation in the short (8 weeks) and long (12 weeks) term to prevent falls among the elderly in the community. CONCLUSION: TC exercises are beneficial for improving balance and muscle strength of the lower limb among the elderly in the community with Selected TC, Traditional TC, and Modified Chen-style TC.


Author(s):  
Moniele Matos Cadamuro ◽  
Durval Ribas Filho

Introduction: In the scenario of vitamin D deficiency, this incident is prevalent and with risks to public health in the world, reaching approximately 90% of individuals. Hypovitaminosis D can cause, mainly in the elderly, lower bone mineral density, fractures, muscle weakness, falls, and acute respiratory infection. Objective: To evaluate the main clinical results on vitamin D levels in the elderly, as well as to analyze which daily or weekly dose of vitamin D is most effective in the elderly in reducing the number of falls and fractures. Methods: The present study developed a systematic review, addressing randomized clinical studies, diverse clinical studies, systematic reviews, meta-analysis, and the latest international consensus, following the rules of PRISMA. Results and Conclusion: A total of 152 articles were found involving the dosage and the impact of vitamin D in the elderly. In total, 72 articles were evaluated in full and 30 were included. According to the main literary findings, vitamin D deficiency implies problems with mineralization and bone mineral density, causing fractures and an increase in the number of elderly falls. In this sense, SBEM recommends maintaining vitamin D concentrations above 30 ng/mL. Also, vitamin D deficiency points to the occurrence of neurological diseases such as cognitive decline, risk of Alzheimer's disease, and depression. In the current scenario of the pandemic, vitamin D points as an important modulator of the immune system, and its deficiency promotes the unregulated release of cytokines, leading to complications in patients with COVID-19.


2019 ◽  
Vol 15 (4) ◽  
pp. 232-237
Author(s):  
Mir Hadi Musavi ◽  
Behzad Jodeiri ◽  
Keyvan Mirnia ◽  
Morteza Ghojazadeh ◽  
Zeinab Nikniaz

Background: Although, some clinical trials investigated the maternal and neonatal effect of fentanyl as a premedication before induction of general anesthesia in cesarean section, to the best of our knowledge, there is no systematic review to summarize these results. Objectives: The present systematic review and meta-analysis evaluated the maternal and neonatal effect of intravenous fentanyl as a premedication before induction of general anesthesia in cesarean section. Methods: The databases of Pubmed, Embase, Scopus and Cochrane library were searched till July 2017 to identify randomized clinical trials which evaluated the effects of intravenous fentanyl as a premedication before induction of general anesthesia compared with placebo on neonate first and fifth minute Apgar score and maternal heart rate and mean arterial pressure (MAP) in cesarean section. Standard Mean difference (SMD) was calculated and I-square statistic test was used for heterogeneity analysis. Results: The present systematic review and meta-analysis consisted of three clinical trials including 180 women in labor. Considering the results of meta-analysis, there is no significant differences between fentanyl and placebo in the case of Apgar score at 1 minute; however, the Apgar score of 5 minutes was significantly lower in fentanyl group compared with placebo (SMD -0.68, 95%CI: - 0.98, -0.38, p<0.001). In the term of maternal hemodynamics, the heart rate (SMD -0.43, 95%CI: - 0.72, -0.13, p=0.004) and MAP (SMD -0.78, 95% CI: -1.09, -0.48, p<0.001) in fentanyl group were significantly lower compared with placebo group. Conclusion: The present meta-analysis showed that using intravenous fentanyl as a premedication before induction of general anesthesia had adverse effects on neonate Apgar score. However, it had positive effects on preventing adverse consequences of intubation on maternal hemodynamics.


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