scholarly journals Current status of human rabies transmitted by dogs in Latin America

2007 ◽  
Vol 23 (9) ◽  
pp. 2049-2063 ◽  
Author(s):  
Maria Cristina Schneider ◽  
Albino Belotto ◽  
Maria Paz Adé ◽  
Saskia Hendrickx ◽  
Luis Fernando Leanes ◽  
...  

Latin American countries made the political decision to eliminate human rabies transmitted by dogs by the year 2005. The purpose of the current study is to evaluate to what extent this goal has been reached. The epidemiological situation and control measures were analyzed and broken down within the countries by georeferencing. The 27 human cases reported in 2003 occurred in some 0.2% of the second-level geopolitical units (municipalities or counties) in the region, suggesting that the disease is a local problem. Several areas within the countries reported no more transmission of rabies in dogs. Nearly 1 million people potentially exposed to rabies received treatment. On average, 34,383 inhabitants per health post receive anti-rabies treatment (range: 4,300-148,043). Nearly 42 million dogs are vaccinated annually. Surveillance is considered fair according to the epidemiological criteria adopted by the study. Samples sent for rabies testing represent 0.05% of the estimated canine population (range: 0.001 to 0.2%). The countries are quite close to achieving the goal.

2001 ◽  
Vol 14 (2) ◽  
pp. 229-243 ◽  
Author(s):  
Emanuela Handman

SUMMARY Leishmaniae are obligatory intracellular protozoa in mononuclear phagocytes. They cause a spectrum of diseases, ranging in severity from spontaneously healing skin lesions to fatal visceral disease. Worldwide, there are 2 million new cases each year and 1/10 of the world's population is at risk of infection. To date, there are no vaccines against leishmaniasis and control measures rely on chemotherapy to alleviate disease and on vector control to reduce transmission. However, a major vaccine development program aimed initially at cutaneous leishmaniasis is under way. Studies in animal models and humans are evaluating the potential of genetically modified live attenuated vaccines, as well as a variety of recombinant antigens or the DNA encoding them. The program also focuses on new adjuvants, including cytokines, and delivery systems to target the T helper type 1 immune responses required for the elimination of this intracellular organism. The availability, in the near future, of the DNA sequences of the human and Leishmania genomes will extend the vaccine program. New vaccine candidates such as parasite virulence factors will be identified. Host susceptibility genes will be mapped to allow the vaccine to be targeted to the population most in need of protection.


1994 ◽  
Vol 24 (97) ◽  
pp. 549-561
Author(s):  
Norbert Lechner

The article investigates the effects of extensive enforcement of the market society on the pattems of politics in the example of the Latin American countries. The institutionalized politics as well as the »political« (the symbolic representations of the collective order) undergo a transformation, during which the context and the meaning of democracy is changed. Instead of politics being trapped within the mere market logic and only reacting to challenges, a policy which tries toregulate social processes with the aim of a collective order for the collectivity is necessary.


2019 ◽  
Vol 37 (9) ◽  
pp. 1813-1821 ◽  
Author(s):  
Pablo Lamelas ◽  
Rafael Diaz ◽  
Andres Orlandini ◽  
Alvaro Avezum ◽  
Gustavo Oliveira ◽  
...  

Parasitology ◽  
2016 ◽  
Vol 145 (1) ◽  
pp. 32-40 ◽  
Author(s):  
I. VYTHILINGAM ◽  
M. L. WONG ◽  
W. S. WAN-YUSSOF

SUMMARYPlasmodium knowlesi a simian malaria parasite is currently affecting humans in Southeast Asia. Malaysia has reported the most number of cases and P. knowlesi is the predominant species occurring in humans. The vectors of P. knowlesi belong to the Leucosphyrus group of Anopheles mosquitoes. These are generally described as forest-dwelling mosquitoes. With deforestation and changes in land-use, some species have become predominant in farms and villages. However, knowledge on the distribution of these vectors in the country is sparse. From a public health point of view it is important to know the vectors, so that risk factors towards knowlesi malaria can be identified and control measures instituted where possible. Here, we review what is known about the knowlesi malaria vectors and ascertain the gaps in knowledge, so that future studies could concentrate on this paucity of data in-order to address this zoonotic problem.


2019 ◽  
Vol 11 (1) ◽  
pp. 3-22
Author(s):  
Luis Roniger ◽  
Leonardo Senkman

Conspiracy discourse interprets the world as the object of sinister machinations, rife with opaque plots and covert actors. With this frame, the war between Bolivia and Paraguay over the Northern Chaco region (1932–1935) emerges as a paradigmatic conflict that many in the Americas interpreted as resulting from the conspiracy manoeuvres of foreign oil interests to grab land supposedly rich in oil. At the heart of such interpretation, projected by those critical of the fratricidal war, were partial and extrapolated facts, which sidelined the weight of long-term disputes between these South American countries traumatised by previous international wars resulting in humiliating defeats and territorial losses, and thus prone to welcome warfare to bolster national pride and overcome the memory of past debacles. The article reconstructs the transnational diffusion of the conspiracy narrative that tilted political and intellectual imagination towards attributing the war to imperialist economic interests, downplaying the political agency of those involved. Analysis suggests that such transnational reception highlights a broader trend in the twentieth-century Latin American conspiracy discourse, stemming from the theorization of geopolitical marginality and the belief that political decision-making was shaped by the plots of hegemonic powers.


1967 ◽  
Vol 29 (1) ◽  
pp. 76-86
Author(s):  
Donald W. Bray

In a majority of Latin-American countries the coup d'etat rather than the ballot is still the institutionalized mechanism for transferring political power. Some states, like Haiti and Paraguay, are clearly in the “prehistory” of modern political parties. Nevertheless, in the twentieth century the political party with a developed ideology has become a major feature of Latin-American political life.


2011 ◽  
Vol 55 (3) ◽  
pp. 340-365 ◽  
Author(s):  
Fabiana Machado ◽  
Carlos Scartascini ◽  
Mariano Tommasi

In this article, the authors argue that where institutions are strong, actors are more likely to participate in the political process through institutionalized arenas, while where they are weak, protests and other unconventional means of participation become more appealing. The authors explore this relationship empirically by combining country-level measures of institutional strength with individual-level information on protest participation in seventeen Latin American countries. The authors find evidence that weaker political institutions are associated with a higher propensity to use alternative means for expressing preferences, that is, to protest.


2004 ◽  
Vol 6 (1) ◽  
pp. 1-35 ◽  
Author(s):  
Witold Henisz

The current level and future evolution of trans-Pacific business linkages are tightly linked to domestic politics in Latin American countries. Where the structure of a nation's political institutions offer credible checks and balances against discretionary policymaking, external linkages including those with Pacific partners are stronger. Future liberalization including the formation of an FTAA is more likely when new policymakers arrive in office or when existing policymakers feel strong internal or external pressure to shift the course of their trade policy. A given liberalization is more likely to be sustained when coupled with short-term observable improvement in social and economic indicators. Countries with political institutions that fail to limit policymakers' discretion are particularly sensitive to a failure to demonstrate clear and immediate results. An analysis of the potential of an FTAA to influence trans-Pacific business linkages based on these arguments suggests that adoption is far from certain and that northern and southern countries alike will have to design an agreement with particular attention to social and economic consequences in Latin American countries.


2021 ◽  
Author(s):  
Paola Karp ◽  
Matías Gatto ◽  
María Victoria Batto ◽  
Sol Ferrero ◽  
Gustavo Helguera

In the last decade, the expiration of patents protecting therapeutic monoclonal antibodies opened an opportunity for the development and approval of biosimilar versions of these drugs. The complexity of these biologic molecules required the imposition of strict regulations to establish robust comparability with the antibody of reference in physicochemical, analytical, biological and, when deemed necessary, clinical data. Accordingly, this period coincides with the updating of the requirements and guidelines for the manufacture and approval of biologics in Latin American countries by their respective regulatory agencies. Although the term “biosimilar” does not appear in the official regulatory provisions in most of the countries, it is of general use in Latin America, and several biosimilars of therapeutic monoclonal antibodies were approved based on comparative quality, nonclinical and clinical data that demonstrate similarity to a licensed biological reference registered before in a Regulatory Health Authority of reference. Here, we provide an overview of how the complexities of therapeutic monoclonal antibodies shaped the regulatory landscape of similar biologics, the current status of biosimilar monoclonal antibodies in Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, México, Paraguay, Perú and Uruguay and their potential to reduce the cost of antibody therapies in this region.


2001 ◽  
Vol 21 (1) ◽  
pp. 65-81
Author(s):  
PAMELA K. STARR

ABSTRACT The capacity of dollarization to generate stable growth in Latin America despite occasional instability in the international financial system has been the subject of significant economic analysis in recent years. Yet very little attention has been afforded to the politics of the issue. This paper attempts to fill this void by looking at both the political and the economic factors which influence the policy effectiveness of dollarization. The paper reviews the theoretic and policy debate within which the dollarization question is situated and then develops an informal model of the political and economic variables which influence the viability of dollarization. It concludes that although dollarization may be the correct policy choice for some Latin American countries, it is unlikely to benefit the majority. Most Latin American countries would benefit more from directly addressing the forces know to promote economic instability.


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