scholarly journals Anesthetic protocol for videolaparoscopic surgery in rabbits

2010 ◽  
Vol 25 (1) ◽  
pp. 121-125 ◽  
Author(s):  
Rosi Pereira Balbinotto ◽  
Manoel Roberto Maciel Trindade ◽  
Fabíola Schons Meyer ◽  
Ana Lucia Letti Muller ◽  
Arlindo da Rosa Jr ◽  
...  
Keyword(s):  
Abdominal Cavity ◽  
Anesthetic Technique ◽  
Intubation Technique ◽  
Mean Values ◽  
Surgical Access ◽  
Duration Of Surgery ◽  
Manual Palpation ◽  
The Mean ◽  
Recovery From Anesthesia ◽  
Vital Parameters

PURPOSE: To describe the anesthetic protocol and the intubation technique without visualizing the trachea in rabbits, in order to enable the videolaparoscopic surgical procedure. METHODS: The experiment was performed on 33 female rabbits (Oryctolagus cuniculus), aged from 5 to 7 months. It consisted of general anesthesia and endotracheal intubation by manual palpation of the trachea of the rabbits, without using the laryngoscope, orally, for later videolaparoscopic surgical access to the abdominal cavity. RESULTS: The mean values and standard deviation of vital parameters of the animals were 223.8±15.61 beats per minute for heart rate; 35±9 movements per minute for respiratory rate; 96.94±0.99% of oxymetry and 42.82±4.02 mmHg for capnometry; 16.7±4.3 minutes for pneumoperitoneum (duration of surgery) and 1 hour and 14±8.52 minutes for time of observation (from induction to recovery from anesthesia). All animals were intubated in at most three attempts. No animals were lost after the introduction of this anesthetic technique. CONCLUSION: This protocol proved adequate, safe and easy to perform, on rabbits submitted to videolaparoscopic surgery.

scholarly journals Assessment of operative times of multiple surgical specialties in a public university hospital

2017 ◽  
Vol 15 (2) ◽  
pp. 200-205 ◽  
Author(s):  
Altair da Silva Costa Jr
Keyword(s):  
Operating Room ◽  
Operative Time ◽  
Cross Sectional Study ◽  
Public University ◽  
University Hospital ◽  
Cross Sectional ◽  
Mean Values ◽  
Operating Room Planning ◽  
Duration Of Surgery ◽  
The Mean

ABSTRACT Objective To evaluate the indicators duration of anesthesia, operative time and time patients stay in the operating rooms of different surgical specialties at a public university hospital. Methods It was done by a descriptive cross-sectional study based on the operating room database. The following stages were measured: duration of anesthesia, procedure time and patient length of stay in the room of the various specialties. We included surgeries carried out in sequence in the same room, between 7:00 a.m. and 5 p.m., either elective or emergency. We calculated the 80th percentile of the stages, where 80% of procedures were below this value. Results The study measured 8,337 operations of 12 surgical specialties performed within one year. The overall mean duration of anesthesia of all specialties was 178.12±110.46 minutes, and the 80th percentile was 252 minutes. The mean operative time was 130.45±97.23 minutes, and the 80th percentile was 195 minutes. The mean total time of the patient in the operating room was 197.30±113.71 minutes, and the 80th percentile was 285 minutes. Thus, the variation of the overall mean compared to the 80th percentile was 41% for anesthesia, 49% for surgeries and 44% for operating room time. In average, anesthesia took up 88% of the operating room period, and surgery, 61%. Conclusion This study identified patterns in the duration of surgery stages. The mean values of the specialties can assist with operating room planning and reduce delays.

scholarly journals Clinical study of intra-abdominal pressure in the acute surgical abdomen

2017 ◽  
Vol 4 (8) ◽  
pp. 2512
Author(s):  
Kumari Neelam ◽  
Amit Kumar ◽  
Vineet Singh ◽  
Surjeet Kumar Yadav
Keyword(s):  
Early Recognition ◽  
Abdominal Cavity ◽  
Study Groups ◽  
Intraabdominal Pressure ◽  
Control Group ◽  
Abdominal Pressure ◽  
Mean Values ◽  
Organ Systems ◽  
The Mean ◽  
A Prospective Study

Background: Intra-abdominal pressure (IAP) is the steady-state pressure concealed within the abdominal cavity. Early recognition of rising abdominal pressure is critically important, because it allows prompt intervention which will prevent Abdominal compartment syndrome (ACS) from developing, leading to a much better prognosis for the patient. This prospective case-control study was aimed at characterisation of this entity in the commonly encountered acute surgical abdomen i.e. perforation peritonitis, intestinal obstruction and the blunt abdominal trauma. The stress was laid upon the detection of the intra-abdominal pressure in the patients and the effect of this entity upon the routinely available clinical and laboratory parameters of organ functions. The organ systems studied were the renal, cardiovascular and the pulmonary systems. The clinical outcome was also analysed.Methods: This is a prospective study conducted in Rajendra Institute of Medical Sciences, Ranchi, Jharkhand over a period of one and half year (January 2014 to June 2015). A total of 120 patients were studied, including 30 as controls. The intra-vesicular pressure was measured in all the subjects, which indirectly gives intraabdominal pressure.Results: Initial intra-abdominal pressure ranged from 0-31 cm of saline with the mean of 13.77±8.46. The mean values of the intra-abdominal pressure in the study groups i.e acute surgical cases were found to be significantly higher, as compared to that of the control group (p<0.01). Highest mortality was observed in the IAP range of >25 cm of saline (33.33%, 4 out of 12).Conclusions: Raised intraabdominal pressure significantly affects outcome and increases mortality.

scholarly journals Adrenal Gland of the Adult female Duck (Anas platyrhynchos)

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Ahmed Obaid Hossein ◽  
Hyder Shkeir
Keyword(s):  
Adrenal Gland ◽  
Adult Female ◽  
Chromaffin Cells ◽  
Anas Platyrhynchos ◽  
Abdominal Cavity ◽  
Zona Glomerulosa ◽  
Relative Volume ◽  
Zona Fasciculata ◽  
Mean Values ◽  
The Mean

 The aim of this study was to investigate the morphological& histological properties of the female Duck (Anas platyrhynchos) adrenal gland in babilon.For this purpose, ten adrenals were collected from five adult female ducks.The ducks have paired glands located in the abdominal cavity at the anterior end of the kidneys.The shape of right gland is semi-circularwhile the left elongated or triangular in shape. The mean weight of the right adrenal gland of duck was 0.39g while the left was o.41g. The relative volume of the components remained essentially the same in both glands.  The mean values of long axis of left adrenal gland 15.46mm and the diameter of right gave mean values 11.30mm.The adrenal cortex is subdivided into three zones. The outermost zone was formed as zona glomerulosa. It contained prismatic cells that formed irregular clusters or cords and contained lipid vacuoles. The second zone is zona fasciculata appeared foamy. The zona reticularis appeared as irregular cords and smaller than other two zones of cortex. Medulla. The adrenal medulla was about one quarter of the area of the gland. The chromaffin cells in irregular clusters,. Epinephrine-storing cells (E-cells) were more numerous and smaller than norepinephrine-storing cells (NE-cells). Both chromaffin cells contained a single large spherical nucleus

scholarly journals The Use of Determinants of Length of Stay in the Post-anesthesia Care Unit (PACU) at the Philippine General Hospital among Postoperative Patients who Underwent Elective Surgeries to Create a Predictive Model for PACU Length of Stay

2020 ◽  
Vol 54 (5) ◽  
Author(s):  
Maria Teresita B. Aspi ◽  
Evangeline Ko-Villa
Keyword(s):  
Length Of Stay ◽  
General Hospital ◽  
Chart Review ◽  
Average Length ◽  
Anesthetic Technique ◽  
Published Data ◽  
Post Anesthesia Care Unit ◽  
Average Length Of Stay ◽  
Duration Of Surgery ◽  
The Mean

Background. The aims of this study were to determine the average length of stay in the Post-anesthesia CareUnit (PACU LOS) in the Philippine General Hospital (PGH) and to create a model that will predict the PACU LOSbased on the factors that significantly affect the LOS. Determination and prediction of PACU LOS is essential inresource utilization, and in cost containment and reduction. Addressing the modifiable variables that affect thePACU LOS may lead to an improvement in the LOS of patients in the PACU and, consequently, to better recoveryroom staffing and a reduced cost for the patients and the hospital. Methods. A prospective chart review of 400 postoperative patients admitted in the PGH PACU was done. Summarystatistics were presented. Using the set of variables found to be significant, a regression model was formulatedto estimate the PACU LOS. Results. The mean PACU LOS was 4.59 hours. There were significant differences in the mean PACU LOS basedon the occurrence of complications. There were also significant differences in the median PACU LOS based onthe type and duration of surgery, anesthetic technique, and duration of anesthesia. The multiple linear regressionmodel that best predicted PACU LOS included ASA-PS classification, type of surgery, duration of surgery, anesthetictechnique, and occurrence of intraoperative or postoperative complications. Conclusions. The mean PACU LOS of the Philippine Genera Hospital is higher than that of published data. Thefactors included in the model that best predicts PACU LOS may be studied to improve the PACU LOS.

scholarly journals Chemical restraint of coatis by the association of Detomidine, Tiletamine and Zolazepam, in allometrically scaled dosages

2021 ◽  
Vol 73 (1) ◽  
pp. 108-114
Author(s):  
R.O. Kunz ◽  
C. Cardeal ◽  
L.E. Riekher Junior ◽  
L.G.E. Valle ◽  
S.T. Belettini ◽  
...  
Keyword(s):  
Adverse Reactions ◽  
Free Living ◽  
Mean Values ◽  
Chemical Restraint ◽  
Loss Of Righting Reflex ◽  
Righting Reflex ◽  
The Mean ◽  
Living Adult ◽  
Respiratory Movements ◽  
Vital Parameters

ABSTRACT Ten free-living adult coatis (two males and eight females) were chemically restrained with "ZAD-50", a concentrated formulation prepared with the dehydrated content of a Zoletil/50® vial diluted with 0.25mL of 1% atropine, 0.265mL of Dormiun-V®, and 2.2mL of distilled water, being exactly 3.0mL. The formula was administered to each animal previously captured and physically contained with a net. The loss of righting reflex (RR) occurred at 2.3±0.8 minutes post-injection (MPI), with anesthesia beginning at 4.4±2.7 MPI. Myorelaxant and analgesia were considered excellent at all moments of the evaluation. Conscious reactions were observed at 78.7±22.2 MPI, the return of the RR occurred at 101 ± 18 MPI, and normal ambulation was acquired at 137.0±31.0 MPI. The mean values of physiological parameters measured every 10 minutes between 10 and 50 MPI were 152.2 heartbeats per minute for heart rate, 66.4 respiratory movements per minute for respiratory rate, 39.2oC for rectal temperature, 86.2% for SpO2 and 14.6 mmHg for systolic blood pressure. In the same times, the EEG registered sinus rhythm. No adverse reactions were observed, and the assessed vital parameters remained compatible with the state of chemical restraint.

Articulatory Behavior Pre and Post Full-Mouth Tooth Extraction and Alveoloplasty

1980 ◽  
Vol 23 (3) ◽  
pp. 630-645 ◽  
Author(s):  
Gerald Zimmermann ◽  
J.A. Scott Kelso ◽  
Larry Lander
Keyword(s):  
Control Subject ◽  
High Speed ◽  
Tooth Extraction ◽  
Kinematic Parameters ◽  
Experimental Conditions ◽  
Mean Values ◽  
Articulatory Movements ◽  
The Mean ◽  
Experimental Subjects ◽  
Normal Speech

High speed cinefluorography was used to track articulatory movements preceding and following full-mouth tooth extraction and alveoloplasty in two subjects. Films also were made of a control subject on two separate days. The purpose of the study was to determine the effects of dramatically altering the structural dimensions of the oral cavity on the kinematic parameters of speech. The results showed that the experimental subjects performed differently pre and postoperatively though the changes were in different directions for the two subjects. Differences in both means and variabilities of kinematic parameters were larger between days for the experimental (operated) subjects than for the control subject. The results for the Control subject also showed significant differences in the mean values of kinematic variables between days though these day-to-day differences could not account for the effects found pre- and postoperatively. The results of the kinematic analysis, particularly the finding that transition time was most stable over the experimental conditions for the operated subjects, are used to speculate about the coordination of normal speech.

Comparative Study of Intranasal, Subcutaneous and Intravenous Administration of Desamino-D-Arginine Vasopressin (DDAVP)

1986 ◽  
Vol 55 (01) ◽  
pp. 108-111 ◽  
Author(s):  
M Köhler ◽  
P Hellstern ◽  
C Miyashita ◽  
G von Blohn ◽  
E Wenzel
Keyword(s):  
Factor Viii ◽  
Von Willebrand Factor ◽  
Factor Xii ◽  
Additional Advantage ◽  
Mean Values ◽  
Routes Of Administration ◽  
The Mean ◽  
Von Willebrand ◽  
Willebrand Factor ◽  
Factor Antigen

SummaryThis study was performed to evaluate the influence of different routes of administration on the efficacy of DDAVP treatment. Ten healthy volunteers received DDAVP intranasally (i.n.), subcutaneously (s.c.) and intravenously (i.v.) in a randomized cross-over trial. Factor XII and high molecular weight (HMW)-kininogen levels increased only slightly after DDAVP administration. The mean increase of factor VIII: C was 3.1 (i. v.), 2.3 (s. c.), and 1.3 (i.n.) - fold over baseline. Ristocetin cofactor (von Willebrand factor antigen) increased 3.1 (2.5), 2.0 (2.3) and 1.2 (1.2) - fold over baseline mean values after i.v., s.c. and i.n. DDAVP, respectively. The half-disappearance time of factor VIII and von Willebrand factor (vWF) after DDAVP ranged from five (factor VIII: C) to eight hours (vWF). The mean increase of fibrinolytic activity was more pronounced after i.v. DDAVP. The antidiuretic effect was moderate with no apparent differences between the routes of application. This study provides further evidence that both i.v. and s.c. DDAVP administration result in an appropriate and reliable stimulation of haemostasis. An additional advantage of s. c. administration is its suitability for home treatment.

Comparative Study of effectiveness of mobilization with movement (MWM) and End range mobilization (ERM) techniques in frozen shoulder

2018 ◽  
Vol 4 (4) ◽  
pp. 519-522
Author(s):  
Jeyakumar S ◽  
Jagatheesan Alagesan ◽  
T.S. Muthukumar
Keyword(s):  
Range Of Motion ◽  
Frozen Shoulder ◽  
Type I ◽  
Mean Values ◽  
Functional Activities ◽  
Group A ◽  
The Mean ◽  
Group B

Background: Frozen shoulder is disorder of the connective tissue that limits the normal Range of motion of the shoulder in diabetes, frozen shoulder is thought to be caused by changes to the collagen in the shoulder joint as a result of long term Hypoglycemia. Mobilization is a therapeutic movement of the joint. The goal is to restore normal joint motion and rhythm. The use of mobilization with movement for peripheral joints was developed by mulligan. This technique combines a sustained application of manual technique “gliding” force to the joint with concurrent physiologic motion of joint, either actively or passively. This study aims to find out the effects of mobilization with movement and end range mobilization in frozen shoulder in Type I diabetics. Materials and Methods: 30 subjects both male and female, suffering with shoulder pain and clinically diagnosed with frozen shoulder was recruited for the study and divided into two groups with 15 patients each based on convenient sampling method. Group A patients received mobilization with movement and Group B patients received end range mobilization for three weeks. The outcome measurements were SPADI, Functional hand to back scale, abduction range of motion using goniometer and VAS. Results: The mean values of all parameters showed significant differences in group A as compared to group B in terms of decreased pain, increased abduction range and other outcome measures. Conclusion: Based on the results it has been concluded that treating the type 1 diabetic patient with frozen shoulder, mobilization with movement exercise shows better results than end range mobilization in reducing pain and increase functional activities and mobility in frozen shoulder.

A COMPARISON OF TWO METHODS FOR MEASUREMENT OF ALDOSTERONE SECRETION RATE IN MAN

1966 ◽  
Vol 53 (2) ◽  
pp. 177-188 ◽  
Author(s):  
P. Lund-Johansen ◽  
T. Thorsen ◽  
K. F. Støa
Keyword(s):  
Urinary Excretion ◽  
Normal Subjects ◽  
Secretion Rate ◽  
Aldosterone Secretion ◽  
Simple Method ◽  
Mean Values ◽  
Pathological Conditions ◽  
Significant Difference ◽  
Derivative Method ◽  
The Mean

ABSTRACT A comparison has been made between (A), a relatively simple method for the measurement of aldosterone secretion rate, based on paper chromatography and direct densitometry of the aldosterone spot and (B) a more elaborate isotope derivative method. The mean secretion rate in 9 normal subjects was 112 ± 26 μg per 24 hours (method A) and 135 ± 35 μg per 24 hours (method B). The »secretion rate« in one adrenalectomized subject after the intravenous injection of 250 μg of aldosterone was 230 μg per 24 hours (method A) and 294 μg per 24 hours (method B). There was no significant difference in the mean values, and correlation between the two methods was good (r = 0.80). It is concluded that the densitometric method is suitable for clinical purposes as well as research, being more rapid and less expensive than the isotope derivative method. Method A also measures the urinary excretion of the aldosterone 3-oxo-conjugate, which is of interest in many pathological conditions. The densitometric method is obviously the less sensitive and a prerequisite for its use is an aldosterone secretion of 20—30 μg per 24 hours. Lower values are, however, rare in adults.

EFFECT OF OESTRONE-PELLET IMPLANTATION ON PLASMA LEVELS OF PROLACTIN

1970 ◽  
Vol 64 (2) ◽  
pp. 265-272 ◽  
Author(s):  
A. A. van der Gugten ◽  
M. Sala ◽  
H. G. Kwa
Keyword(s):  
Plasma Levels ◽  
Male Rats ◽  
Mean Values ◽  
The Mean ◽  
Dose Levels ◽  
Higher Doses ◽  
Primary Break

ABSTRACT Eight female and eight male rats were castrated at the age of 8 to 10 weeks. Four spayed and four orchidectomized rats received one oestrone/cholesterol pellet (200 μg oestrone) on the day of operation (day 0), a second pellet on day 11 and a third on day 23. The remaining animals received four oestrone/cholesterol pellets at these times. The fluctuations in the prolactin levels in the circulation induced by the oestrogen challenges in these animals were followed during 31 days by radioimmunoassays performed on days 3, 7, 9, 14, 15, 17, 23, 24, 25, 28 and 31. The results suggested that the homoeostatic mechanism regulating plasma levels of prolactin was capable of withstanding the three time-spaced oestrogen challenges only in the spayed animals receiving the lower doses of oestrogen, since it allowed the mean values of the prolactin levels to remain fairly constant during the first 4 weeks. The levels in this group rose to much higher levels only on day 31. The higher doses of oestrone in the spayed rats and both dose levels of oestrone in the orchidectomized animals apparently resulted in a primary break-down of the homoeostatic mechanism, since the prolactin levels in the animals of these groups rose to much higher levels either on day 7 or on day 9. This was followed by a period during which the prolactin levels appeared to be more or less under control, until a second and probably definitive failure of the homoeostatic mechanism allowed the mean levels to rise sharply again.

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