scholarly journals Sinus maxillaris mycetoma of odontogenic origin: case report

2004 ◽  
Vol 15 (3) ◽  
pp. 248-250 ◽  
Author(s):  
Matjaz Rode ◽  
Jernej Podboj ◽  
Mirela Kogoj-Rode

Fungal infections are on the increase and those of the jaw cavities with Aspergillus species may be connected with the root apices of teeth in the upper jaw. Diagnostic changes in the sinus maxillaris and certain types of facial pain may be indicative of fungal infection. The authors report a case of aspergillosis sinusitis and describe the diagnostic methods and treatment of this infection that may be associated with endodontic treatment.

2019 ◽  
Vol 8 (1) ◽  
pp. 6-15
Author(s):  
P. M. Ridzuan ◽  
C. M. Nazira ◽  
Manuel Ruth ◽  
C. N. Abdul Rassip ◽  
M. H Nur Raihan ◽  
...  

Dermatomycosis is a fungal infection of the skin, hair and nail caused by Trichophyton, Microsporum and Epidermophyton. These organisms are found in the environment, humans and animals in forms of yeast or mold. There are many factors that contribute to the growth of fungal infections in human body. But still majority of virulent factors and mechanisms of the diseases of fungi are not clear. This review paper describes types of fungal infections, their classification, epidemiology and new insights into pathogenesis with the focus on molecular mechanisms of the diseases. Furthermore, traditional and novel molecular diagnostic methods and the variety of drug treatment and the development of resistance against these drugs are discussed.


2013 ◽  
Author(s):  
Sara Buckman ◽  
Luis A. Fernandez

Fungal infections remain an important cause of morbidity and mortality in surgical settings, with critically ill patients, transplant patients, and sick neonates all being especially vulnerable. Over the past few decades, technological and scientific advancements have improved physicians’ ability to sustain life in critically ill patients, developments in chemotherapeutics and immune-based therapies have yielded increased survival for many cancer patients, organ transplantation has evolved dramatically, and the use of invasive therapies has increased markedly. With these changes has come an increase in the incidence of serious Candida infections, as well as an increase in the less common but potentially fatal noncandidal infections caused by Aspergillus and the Zygomycetes Mucor and Rhizopus. Antifungal prophylaxis has emerged as a potential means of reducing the occurrence of serious fungal infections. This review covers fungal colonization versus infection, types of fungal infection, epidemiology and risk factors, clinical evaluation, investigative studies, management of acute candidemia and acute disseminated candidiasis, management of nonhematogenous candidiasis, peritonitis and intra-abdominal abscess, management of other fungal infections (Aspergillus, Cryptococcus, Mucor, Rhizopusi), systemic antifungal agents, and the pathogenesis of Candida infection. Tables describe the clinical presentation and diagnostic methods for common fungal infections, antimicrobial agents of choice for candida infections, antifungal chemotherapy, and characteristics of currently available antifungals. Figures show Candida endophthalmitis; superficial candidiasis; biopsy samples of chronic progressive disseminated histoplasmosis and thick-walled, broad-based budding yeasts typical for Blastomyces dermatitidis; and the various forms of Candida. Algorithms demonstrate the approach to the surgical patient at risk for candidiasis, aspergillosis, and other types of fungal infection. This review contains 5 figures, 4 tables, and 189 references.


2020 ◽  
Author(s):  
CHARLES XIAOXIANG ZHU

Abstract Background The cause of many rheumatic diseases is still unknown. Some Infections might play a role, but the causative evidence is far from definitive. In this arthritic case, an association between a chronic foot fungal infection with Aspergillus sydowii (Aspsy) and arthritis was initially suggested when the treatment of foot hyperkeratosis-like lesions (Xiangya lesions) provoked multiple joints arthritis symptoms. In order to find the association of fungal infection and arthritis, data from scrupulous observations of plantar lesions, arthritic symptoms, and weather features in events of the fungal infection relapses, foot lesion manipulation, or subcutaneous injection of fungal secreted proteins were gathered and analyzed in three years. Case presentation Of the patient, relapses of the fungal infections on Xiangya lesions often occurred after rainy and humid days in winter and spring. Significant relapses of the infection aggravated the symptoms of arthritis within a few days, and the symptoms gradually improved in 2-3 weeks after the remission of fungal infection by topical antifungal treatment. Also, repeated trimming/debriding Xiangya lesion or subcutaneous injection of fungal secreted proteins also induced the arthritis symptoms similar to those of foot fungal infections. Arthritis Dermatitis, bradycardia, hypertension, and elevated blood monocytes were concurrent abnormalities. Topical methotrexate on the fresh trimmed plantar lesions was able to prevent and relieve arthritis. Conclusions Active fungal infections on plantar Xiangya lesions were associated with cold and humid weather in winter-spring or partial lesion debridement. The active fungal infections induced and exacerbated arthritis, dermatitis, and cardiovascular abnormalities. Fungal secreted proteins may mediate the fungal pathogenicity. Effective treatments of the fungal infection improved arthritis and dermatitis. These pathological characteristics have not been described before and could be a new disease, or one of the unknown pathogenic mechanisms for some known rheumatic diseases, such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis. The results of this research may provide an insight into a novel pathogenic mechanism for some chronic arthritis and may shed light on further clinical studies on the pathogenesis and environmental factors of some rheumatic diseases. Keywords: Arthritis of fungal protein, Aspergillus skin infection, rheumatic diseases pathogenesis, methotrexate, case report


Author(s):  
Deepak Chaudhary ◽  
Ashish Behera ◽  
Navneet Sharma

Mucormycosis is an opportunistic fungal infection that occurs primarily in immunocompromised individuals, usually affecting the rhino-orbital areas followed by the lungs. This case report presents renal mucormycosis in a young man after COVID-19 pneumonia that escalates the need for regular follow-up of COVID-19 patients. Post-COVID-19 fungal infections are on a steep rise, and the increased use of steroids and immune modulators for COVID-19-associated immune dysregulation and cytokine syndrome increases the risk among patients treated for COVID-19.


1992 ◽  
Vol 13 (4) ◽  
pp. 152-156
Author(s):  
James E. Rasmussen

Cutaneous fungus infection in children may be either superficial or deep. The most common superficial infections include tinea versicolor, tinea capitis, tinea corporis, tinea cruris, tinea pedis, and candidiasis. "Ringworm" is a common term used to describe these infections, stemming from the fact that "tinea" is Latin for "worm" or "moth." The only deep fungal infection discussed in this review is sporotrichosis. Diagnostic Methods All forms of superficial fungal infection can be diagnosed easily with a variety of quick, simple, and inexpensive diagnostic methods. Once mastered, the tests need not be used on patients with obvious diagnoses; nevertheless, confirmation of one's clinical impression is personally satisfying and often important. POTASSIUM HYDROXIDE Superficial fungal infections of the skin involve the outer portion of the epidermis, including the hair and nails. Hyphae and spores are visible easily with low-to-moderate microscopic magnification. With the exception of mucous membranes or eroded surfaces (as often found in the case of candidiasis), skin and hair for sampling should be moistened with a drop of water or an alcohol swab. The skin should be abraded gently with the round belly of a 15 blade at the active margin of tinea corporis or, in the case of tinea capitis, any place where alopecia is visible.


2016 ◽  
Vol 3 (1) ◽  
pp. 1-4
Author(s):  
Malaz Mohamed EL-Rafie Mustafa ◽  
Asmaa Awad Mosfer Almosa ◽  
Amira Mosfer Saad Alshahrani ◽  
Sana Mofleh Alshahrani

2018 ◽  
Author(s):  
Ingrid Różyło-Kalinowskav ◽  
Karolina Sidor

The purpose of this article was to present a case report of 11–year old female patient with a large osteolytic mandibular lesion which healed after endodontic treatment. The patient was referred for radio diagnostics due to an incidental finding of a large osteolytic lesion of the area of the left lower first and second premolars in the panoramic radiograph taken before orthodontic treatment. CBCT was performed and the patient asked to have teeth 33-35 treated by endodontics before surgery. The patient missed the surgical appointment and when she reappeared several months later, the lesion showed signs of healing thus surgery were aborted. The presented case testifies to the observation that even large osteolytic lesions can heal after endodontic treatment without surgical approach.


2017 ◽  
Vol 68 (11) ◽  
pp. 2566-2569 ◽  
Author(s):  
Elena Rusu ◽  
Ionela Sarbu ◽  
Magdalena Mitache ◽  
Horatiu Moldovan ◽  
Carmen Ioana Biris ◽  
...  

The high frequency of occurrence of candidiasis as well as high mortality of patients with immunosuppression cause a tendency toward better understanding of Candida albicans species virulence factors and developing sensitive and specific diagnostic methods, and appropriate strategies of candidiasis treatment. In recent decades the incidence of fungal infections has alarming increases because of advanced medical treatments. In this study was analyzed possible ultrastructural changes of the species C. albicans cells following treatment with sodium diclofenac at various concentrations. Following treatment of C. albicans cells with sodium diclofenac 1 mM and 2 mM changes in the plasmalemma can be noticed, changes in the density of cell wall, disruption and necrotic appearance of the cytoplasm.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sawsan Ismail ◽  
Munawar Hraib ◽  
Rana Issa ◽  
Thanaa Alassi ◽  
Zuheir Alshehabi

Abstract Background Ovarian steroid cell tumors represent a rare category of sex cord-stromal tumors that constitute less than 0.1% of all ovarian tumors. These neoplasms are classified into three main subtypes according to the cell of origin: Leidyg cell tumors, stromal luteomas, and steroid cell tumors not otherwise specified (SCTs-NOS). The latter subtype is defined as a neoplasm of an uncertain lineage that mostly affects middle-aged women, whereas it’s rare in younger ages. Case presentation We report a case of a 21-year-old virgin female who presented to our hospital with complaints of mild abdominal pain, hirsutism, and oligomenorrhea for more than a year. Before her current admission, the patient had attended an external gynecologic clinic where she had been prescribed oral contraceptives to regulate her periods. Nevertheless, on presentation to our institution, physical examination revealed abdominal tenderness with a palpable pelvic mass and mild hirsutism in the thigh. Ultrasonography demonstrated a large left ovarian mass measuring 154 × 104 mm, and compressing the uterus. Therefore, a unilateral salpingo-oophorectomy was performed, and interestingly, pathologic examination of the large aforementioned mass alongside with immunohistochemical correlation revealed the diagnosis of a large ovarian steroid cell tumor-not otherwise specified with a unique combination of benign and malignant features. Conclusions Although ovarian steroid cell tumors represent a rare category, they must be considered in the differential diagnosis for mild virilization symptoms in young females due to the importance of early diagnosis and management. In this manuscript, we aimed to present the first case report from Syria that highlights the crucial role of detailed morphological examination for challenging cases despite the difficulties in differential diagnosis, and the absence of ancillary techniques. Furthermore, we managed to discuss a brief review of diagnostic methods, histological characteristics, and treatment recommendations.


2021 ◽  
Vol 7 (8) ◽  
pp. 639
Author(s):  
Yae-Jee Baek ◽  
Yun-Suk Cho ◽  
Moo-Hyun Kim ◽  
Jong-Hoon Hyun ◽  
Yu-Jin Sohn ◽  
...  

(1) Background: Lung transplant recipients (LTRs) are at substantial risk of invasive fungal disease (IFD), although no consensus has been reached on the use of antifungal agents (AFAs) after lung transplantation (LTx). This study aimed to assess the risk factors and prognosis of fungal infection after LTx in a single tertiary center in South Korea. (2) Methods: The study population included all patients who underwent LTx between January 2012 and July 2019 at a tertiary hospital. It was a retrospective cohort study. Culture, bronchoscopy, and laboratory findings were reviewed during episodes of infection. (3) Results: Fungus-positive respiratory samples were predominant in the first 90 days and the overall cumulative incidence of Candida spp. was approximately three times higher than that of Aspergillus spp. In the setting of itraconazole administration for 6 months post-LTx, C. glabrata accounted for 36.5% of all Candida-positive respiratory samples. Underlying connective tissue disease-associated interstitial lung disease, use of AFAs before LTx, a longer length of hospital stay after LTx, and old age were associated with developing a fungal infection after LTx. IFD and fungal infection treatment failure significantly increased overall mortality. Host factors, antifungal drug resistance, and misdiagnosis of non-Aspergillus molds could attribute to the breakthrough fungal infections. (4) Conclusions: Careful bronchoscopy, prompt fungus culture, and appropriate use of antifungal therapies are recommended during the first year after LTx.


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