Bipolar depression: the importance of being on remission

OBJECTIVE: The aim of the present study is to compare quality of life among currently depressed, subsyndromal and remitted patients with bipolar disorder (BD) and to assess whether the level of depression correlates with the scores of quality of life in BD patients. METHOD: Sixty bipolar outpatients diagnosed using the Structured Clinical Interview for DSM-IV who met criteria for diagnosis of BD type I, II or not otherwise specified (BD-NOS), and who were not currently on a manic or mixed episode were included. The main variables of interest were quality of life (QOL) assessed using the 26-item World Health Organization QOL instrument (WHOQOL-BREF) and depression assessed using the 17-item Hamilton Depression Rating Scale (HDRS). RESULTS: A linear trend test showed a dose response association between patients' current mood state and all domains of quality of life. Higher quality of life scores were found among remitted patients, followed by subsyndromal patients; depressed patients presented lower scores of quality of life, except for the social domain. The four domains of the WHOQOL scale correlated negatively with the HDRS. CONCLUSIONS: Our findings suggest that bipolar depression and residual symptoms of depression are negatively correlated with QOL in BD patients.

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An indian study of health related quality of life in bipolar disorder patients and their caregivers

European Psychiatry ◽

10.1016/s0924-9338(11)71929-0 ◽

2011 ◽

Vol 26 (S2) ◽

pp. 219-219

Author(s):

P. Kumar ◽

M.S. Bhatia ◽

S. Mittal ◽

B. Tomar

Keyword(s):

Quality Of Life ◽

Bipolar Disorder ◽

Rating Scale ◽

Bipolar Depression ◽

Bipolar Affective Disorder ◽

World Health ◽

Health Related Quality ◽

Related Quality ◽

Health Related

IntroductionThere are major health care implications of quality of life (QOL) in longstanding disorders such as Bipolar affective disorder (BD) for the patients and their caregivers.ObjectivesThe aim of the present study is to compare quality of life among bipolar disorder patients, their caregivers and to assess whether the level of depression correlates with the scores of quality of life in Bipolar Disorder patients.MethodWe compared bipolar disorder (N = 40), their caregivers (N = 40) and no psychiatric illnesses (N = 150) on health related quality of life (HRQOL) which was assessed using the 26-item World Health Organization QOL instrument (WHOQOL-BREF Hindi version). All patients were diagnosed using the Structured Clinical Interview for DSM IV. Within the group with bipolar disorder, we examined the relationship between HRQOL using WHOQOL BREF Hindi version and depression assessed using the 17-item Hamilton Depression Rating Scale (HDRS).ResultsPatients in bipolar disorder group had lower QOL on all the four domains compared to healthy controls, caregivers. The four domains of the WHOQOL scale correlated negatively with the HDRS.ConclusionsOur findings suggest that bipolar depression and residual symptoms of depression are negatively correlated with QOL in BD patients.

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Quality of Life in Bipolar Type I Disorder in a One-Year Followup

Depression Research and Treatment ◽

10.1155/2012/860745 ◽

2012 ◽

Vol 2012 ◽

pp. 1-11 ◽

Cited By ~ 3

Author(s):

Homayoun Amini ◽

Vandad Sharifi

Keyword(s):

Quality Of Life ◽

World Health ◽

Outcome Variable ◽

Short Version ◽

Assessment Procedure ◽

Type I ◽

Bipolar I Disorder ◽

One Year ◽

Bipolar Patients

Objectives. The aims of this study were (i) to compare Quality of Life (QOL) of patients with bipolar disorder (BD) type I to those with schizophrenia during a one-year period after hospitalization and (ii) to assess the association of different domains of QOL with severity of clinical symptoms and level of functioning in bipolar patients group.Method. A hundred and two participants were consecutively recruited before discharge from an acute hospitalization. To measure QOL as the main outcome variable, the Farsi (Persian) version of the World Health Organization's QOL Instrument Short Version (WHOQOL BREF) was used. Affective symptoms, overall functioning, and severity of mental illness were assessed as well. The assessment procedure was repeated four, eight, and 12 months after discharge.Results. No significant differences were found between patients with BD and schizophrenia on four domains of WHOQOL BREF at the baseline and the four, eight, and 12 month assessments. Within the subjects with bipolar I disorder, the most stable finding was negative association of depression severity with WHOQOL-BREF on the all four domains during repeated assessments.Conclusion. The findings suggest that persistent depressive symptoms might be the primary determinant of impaired QOL in patients with bipolar I disorder.

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Prevalence and correlates of depression and quality of life among primary caregivers of patients with schizophrenia attending a Nigerian Tertiary Hospital

BJPsych Open ◽

10.1192/bjo.2021.72 ◽

2021 ◽

Vol 7 (S1) ◽

pp. S3-S4

Author(s):

Akinloye Akinfala ◽

Oladipo Sowunmi ◽

Imam Sakeeb

Keyword(s):

Quality Of Life ◽

Mental Illness ◽

Rating Scale ◽

Primary Caregivers ◽

Previous Treatment ◽

Female Gender ◽

World Health ◽

World Health Organization Quality ◽

Prevalence Of Depression

AimsTo determine the prevalence and correlates of depression and quality of life and their relationship among primary caregivers of patients with schizophrenia in a psychiatry specialist hospital.MethodA total of 138 caregivers of patients diagnosed with schizophrenia attending the outpatient clinic of the Neuropsychiatric Hospital Aro, Abeokuta were recruited. Sociodemographic questionnaire, Mini International Neuropsychiatric Interview (MINI-PLUS) (depressive module) and World Health Organization Quality of Life-Bref (WHOQOL-Bref) were administered on the caregivers while Brief Psychiatric Rating Scale (BPRS) was used to measure symptoms severity in the patients.ResultThe mean (±SD) age of respondents was 48.3 years (±14.7), 53.6% were females and 33.3% were without partners. The prevalence of depression among the caregivers who participated in the study was 13.8%. Female gender (χ2 = 5.68, df = 1, p = 0.02), hailing from a minority tribe (χ2 = 9.78 df = 1, p < 0.01), and Previous treatment for mental illness (χ2 = 8.24 df = 1, p < 0.01) were associated with depression. Female gender (ß = 1.35, OR = 3.86, p = 0.03), minority tribe (ß = 1.95, OR = 7.03, p < 0.01), and previous treatment for mental illness (ß = 3.19, OR = 24.21, p = 0.01) were independently predictive of depression in the caregivers.Independent predictors of lower quality of life (QOL) were: Parents/siblings relationship for social relationship domain (ß = −7.076, p = 0.037) and spending more than 35 hours per week for Environmental domain (ß = −5.622, p = 0.028).Finally, a significant correlation was also found between Depression and Psychological Domain of QOL (t = 3.048, p < 0.01) and Social Domain of QOL (t = 2.154, p = 0.03).ConclusionThis study shows that primary caregivers of patients with schizophrenia have high prevalence of depression and poor quality of life. There is need to pay attention to the psychological wellbeing and quality of life of caregivers who come in contact with psychiatric services, and not just the patients they accompany.

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Quality of Life of Parents of Children with Type I Diabetes Mellitus, Baghdad 2017

AL-Kindy College Medical Journal ◽

10.47723/kcmj.v17i2.536 ◽

2021 ◽

Vol 17 (2) ◽

pp. 107-114

Author(s):

Sadik Jaafar Shukur ◽

Wijdan Akram Hussein ◽

Nazik L. Kadhum

Keyword(s):

Quality Of Life ◽

Diabetes Mellitus ◽

World Health Organization ◽

World Health ◽

Type I ◽

Healthy Children ◽

Social Domain ◽

Chronic Hyperglycemia ◽

Health Organization

Background: Diabetes is defined by the World Health Organization as a metabolic disorder characterized by chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both. Families are co-regulating systems in which the stresses and strains of one family member affect the well-being of another member of the family. Caregivers of children with chronic illness report experiencing more parental stress than parents of healthy children. Objective: A descriptive cross-sectional study had been conducted in four centers of endocrine diseases in Baghdad city and data was collected by using self-administered questionnaire regarding quality of life adapted from World Health Organization. The study was conducted on six hundred participants. Data analysis was done by using frequency, percentage and mean and analytical statistics using Chi Square test. P value less than 0.05 was considered statistically significant. Results: The study showed that social domain had the highest mean score of (51.1) and that environmental domain had the lowest mean score of (38.9). The physical domain’s mean score was (40.2), while mean score of psychological domain was (46.2). The study reported that mothers of children with type 1 diabetes mellitus were more affected than fathers in physical, psychological and environmental domains. There was no difference between mothers and fathers in social domain of quality of life. Conclusion: It was concluded from the study that parents of diabetic children had generally poor quality of life that merits further investigations.

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Endometriosis and Infertility: Impact on Sexuality

Klinička psihologija ◽

10.21465/2016-kp-op-0042 ◽

2016 ◽

Vol 9 (1) ◽

pp. 65-65

Author(s):

V. Rossi ◽

◽

E. Viozzi ◽

F. M. Nimbi ◽

F. Tripodi ◽

...

Keyword(s):

Quality Of Life ◽

Relationship Satisfaction ◽

Sexual Functioning ◽

Female Sexuality ◽

Rating Scale ◽

Clinical Profile ◽

World Health ◽

World Health Organization Quality ◽

Health Organization

Objective: Endometriosis is a condition that has a great impact on women’s life. One of the most important consequences of the disease is infertility that may exacerbate the psychological, relational and sexual consequences on patients. The aim of the present study was to examine quality of life, anxiety, sexual functioning and relationship satisfaction of women with endometriosis and infertility. Infertility is supposed to be associated with a worse clinical profile. Design and Method: Data were collected on 71 patients (39 women with endometriosis and 32 with endometriosis and infertility) aged between 20 and 50 (M=34.21, SD=8.38), recruited in the Gynecological and Obstetrics department of Policlinico Umberto I, Rome. Participants completed: a socio-demographic questionnaire, the World Health Organization Quality of Life (WHOQOL)-Bref for quality of life, the McCoy Female Sexuality Questionnaire (MFS-Q) for sexual and relationship satisfaction, the Female Sexual Functioning Index (FSFI) for sexual functioning and the Hamilton Anxiety Rating Scale (HAM-A) for anxiety symptoms. Results: Women without infertility obtained worse scores: sexual functioning (F(1,69)=10.97 p<.01), sexual (F(1,69)=17.44 p<.001) and relationship satisfaction (F(1,69)=10.18 p<.001) and quality of life (F(1,69)=13.56 p<.001). Conclusions: Contrary to our hypothesis, endometriosis, with or without fertility impairment, has an impact on patients’ relationship, sexuality and quality of life. Therefore, infertility is not the main factor that explains a negative clinical profile. The present study suggests the importance of psychosexual counseling during medical treatment of the disease, and the need of involving partners in the assessment and in the health care decision making.

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Decreased anxiety after Dawood fasting in the pre-elderly and elderly

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2017-0172 ◽

2018 ◽

Vol 16 (1) ◽

Cited By ~ 3

Author(s):

Ika Fidianingsih ◽

Nur Aisyah Jamil ◽

Russy Novita Andriani ◽

Wira Muhammad Rindra

Keyword(s):

Quality Of Life ◽

Rating Scale ◽

Ketone Bodies ◽

The Elderly ◽

World Health Organisation ◽

World Health ◽

Control Group ◽

Control Group Design ◽

Significant Difference

Abstract Background A high prevalence of anxiety in the elderly often leads to decreased quality of life (QOL). A restrictive diet can increase the production of ketone bodies that encourage mood enhancement, neural protection and pain reduction. This study aimed to identify whether Dawood fasting could increase the QOL of the elderly by reducing anxiety. Methods This research was a quasi-experimental study involving a pretest–post-test control group design. The subjects were pre-elderly and elderly or healthy people aged more than 50, and a consecutive sampling method was employed. The fasting group observed the fast of Dawood, in which they abstained from eating, drinking, or having sexual intercourse from the break of dawn to dusk with the expressed intent to fast every other day. The fast was observed for 22 days (11 fasting days). Anxiety was examined using the Hamilton Rating Scale for Anxiety (HRS-A), while QOL was identified using the Indonesian version of the World Health Organisation Quality of Life (WHOQOL). Results A total of 48 respondents participated in this study with 24 respondents observing the fast of Dawood and 24 others not fasting. Results showed that the 22 days of Dawood fast reduced respondents’ complaints about anxiety by 4.37% and was significantly different from the non-fasting group (p=0.001). There was an increase in the QOL of the fasting group (p=0.019), although no significant difference was found when compared to the non-fasting group. Conclusions The fast of Dawood reduced anxiety in the pre-elderly and elderly.

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Effect of Demographic Factors on Quality of Life in Children with ADHD under Atomoxetine Treatment: 1-Year Follow-up

Journal of Child Science ◽

10.1055/s-0040-1717104 ◽

2020 ◽

Vol 10 (01) ◽

pp. e163-e168

Author(s):

Moustafa M. Ragab ◽

Ehab M. Eid ◽

Nahla H. Badr

Keyword(s):

Quality Of Life ◽

Rating Scale ◽

Multivariate Regression Analysis ◽

World Health ◽

Life Questionnaire ◽

Parent Rating ◽

World Health Organization Quality ◽

Children With Adhd ◽

Atomoxetine Treatment

AbstractAttention-deficit hyperactivity disorder (ADHD) is the most common psychiatric disorder in children and adolescents. Symptoms of ADHD and its treatment can impact an individual's quality of life (QoL). The present study aimed to evaluate the effect of atomoxetine treatment, demographic characteristics, and seasonal variation on QoL in children with a recent diagnosis of ADHD and their parents. The present study included a cohort of 200 children diagnosed with ADHD. In addition to the recruited children, one of their parents was included in the study. ADHD symptoms were assessed using Conners' Parent Rating Scale. QoL of the participants was assessed with the PedsQL, while parents' QoL was evaluated using the World Health Organization Quality of Life questionnaire (WHOQOL-Bref). There was significant improvement in pediatric and parental QoL after treatment with atomoxetine. Significant factors related to better QoL in the participants included spring season, above average Conner's score, male sex, and rural residence. However, after using multivariate regression analysis, only patients' sex and Conner's score were significant predictors of pediatric QoL at the end of treatment with atomoxetine. Medical treatment significantly improved QoL in children with ADHD and their parents. Level of improvement was affected by patients' sex and ADHD severity.

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Social Isolation, Illness Anxiety, and Quality of Life in Corona Survivors

Pakistan Journal of Psychological Research ◽

10.33824/pjpr.2021.36.4.28 ◽

2021 ◽

Vol 36 (4) ◽

pp. 515-528

Author(s):

Shiza Shahid ◽

Amina Shahid ◽

Izza Mahfooz

Keyword(s):

Quality Of Life ◽

Social Isolation ◽

Psychological Health ◽

Rating Scale ◽

Negative Relationship ◽

World Health ◽

Illness Anxiety ◽

The Relationship

The aim of this study was to investigate the relationship between social isolation, illness anxiety and quality of life in corona survivors. This paper focuses on moderating role of illness anxiety on the relationship between social isolation and quality of life of COVID-19 survivors who faced this disease in past 6 months. The sample comprised of 110 survivors of COVID-19. Purposive sampling was used to assess the participants with the help of Google forms. Social isolation was measured by using Lubben Social Network Scale (Lubben et al., 2006), quality of life was measured by WHOQOL-BREF (World Health Organization, 1996), and to measure illness anxiety Hamilton Anxiety Rating Scale (Hamilton, 1959) was used. Correlational analysis revealed that social isolation had positive relationship with illness anxiety. Illness anxiety had negative relationship with physical health, psychological health environment and overall quality of life. Moreover, moderation analysis revealed that illness anxiety significantly moderated the relationship between social isolation and quality of life. This research attempted to explore the social isolation during lock down and illness anxiety corporate in low quality of life in COVID-19 pandemic. This study has variety of clinical implications as this research gave us insight into the role of social isolation and illness anxiety on quality of life especially in this pandemic so it will help psychologists to take measurements accordingly.

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Quality of life of treated patients with Mirizi syndrome

Klinicheskaia khirurgiia ◽

10.26779/2522-1396.2021.1-2.69 ◽

2021 ◽

Vol 88 (1-2) ◽

pp. 69-72

Author(s):

F. M. Pavuk

Keyword(s):

Quality Of Life ◽

Rating Scale ◽

Biliary Fistula ◽

Type I ◽

Type Ii ◽

Mean Values ◽

Gastrointestinal Symptom Rating Scale ◽

Before And After ◽

Assess Quality

Objective. To compare the quality of life of patients with spontaneous internal biliary fistula (SIBF) and without them, before and after surgery. Materials and methods. 82 (38.7%) patients were diagnosed with Mirizzi syndrome (MS) type I, and 130 (61.3%) patients with type II (II-V) type MS. During the study, the classification of A. Csendes - M. Beltran was used. By sex, patients were distributed as follows: there were 68 men (32.0%), women - 144 (68.0%). The age of patients ranged from 37 to 80 years (average - 66.4 years). The GSRS (Gastrointestinal Symptom Rating Scale) questionnaire was used to assess quality of life. When comparing groups, the use of Student's T test comparative mean values and quadratic deviations. The reliability of the obtained p values were checked by the method of Bonferoni and False Discovery Rate (FDR). Results. Multiple comparisons with Bonferon and FDR correction revealed statistically significant differences in the results between QOL of patients with MS I and II both before and after surgery. When compared on the scale of total measurement, it was found that the quality of life of patients without SIBF improved by 11% after cholecystectomy in MS I type. When comparing the results of QOL assessment before and after surgery in patients with type II MS, it was found that QOL after surgery in patients improved by 10% from baseline. Conclusions. The quality of life of patients with MS I type is higher compared to patients with SIBF both before and after surgery (p=0.0001), which is due to impaired bile duct and gastrointestinal tract in SIBF. Elimination of SIBF improves the level of QOL of patients by 10%, which is characterized by a decrease in all items of the GSRS scale.

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The Dimensions of Auditory Hallucination in Schizophrenia: Association with Depressive Symptoms and Quality of Life

IIUM Medical Journal Malaysia ◽

10.31436/imjm.v16i2.325 ◽

2020 ◽

Vol 16 (2) ◽

Author(s):

Janaki V ◽

Suzaily W ◽

Abdul Hamid AR ◽

Hazli Z ◽

Azmawati MN

Keyword(s):

Quality Of Life ◽

Depressive Symptoms ◽

Rating Scale ◽

Auditory Hallucination ◽

Depression Scale ◽

Cross Sectional Study ◽

World Health ◽

Cross Sectional ◽

World Health Organization Quality

Introduction: Auditory hallucination (AH) is often unexplored in depth in clinical practice. This study sought to ascertain the relationship between AH, depressive symptoms and quality of life (QOL) and its association with socio-demographic and clinical variables. Methods: This was a cross sectional study done in a psychiatry unit involving 60 schizophrenic patients between 18 to 60 years old. Psychotic Symptom Rating Scale – Auditory Hallucination subscale (PSYRATS-AH), Calgary Depression Scale for Schizophrenia (CDSS) and World Health Organization Quality of Life-Brief scale (WHOQOL-BREF) were used as instruments. Results: Alcohol intake was found to be significantly associated with the severity of AH. A significant moderate positive correlation was found between AH total score and CDSS (r=0.53, p<0.001) and moderately high correlation between emotional characteristics subscale with CDSS (r=0.651, p<0.005). The PSYRATS-AH dimensions; amount of distress (r=0.721, p<0.001) and intensity of distress (r=0.757, p<0.001) showed significant high correlation with CDSS. As for QOL, frequency of AH (r=-0.419, p<0.01) and CDSS (r=0.435, p<0.01) showed significant moderate negative correlation, while duration, loudness, amount and intensity of distress, disruption to life and controllability of voices had significant fair correlation with QOL. Multiple regression analysis revealed that the frequency of AH (p=0.047), controllability of AH (p=0.027) and depressive symptoms (p=0.001) significantly predict QOL. Conclusion: Our results demonstrated that each dimension of AH had different contributions towards depressive symptoms and the QOL in patients with schizophrenia. Therefore, appropriate treatment focusing on the specific dimension of AH not only may reduce depressive symptoms, but may also improve QOL of these patients.

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