Demographic and Reproductive Factors Associated with Hemifacial Microsomia

2004 ◽  
Vol 41 (5) ◽  
pp. 494-500 ◽  
Author(s):  
Martha M. Werler ◽  
Jane E. Sheehan ◽  
Catherine Hayes ◽  
Bonnie L. Padwa ◽  
Allen A. Mitchell ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Body Mass ◽  
Vaginal Bleeding ◽  
Family Income ◽  
Reproductive Factors ◽  
The United States ◽  
Hemifacial Microsomia ◽  
Second Trimester ◽  
Craniofacial Malformations

Objective To identify demographic and reproductive risk factors for hemifacial microsomia in offspring. Design In a case-control study, maternal interviews were conducted within 3 years after delivery. Cases with hemifacial microsomia were ascertained from craniofacial centers in 26 cities in the United States and Canada. Controls were patients of the cases’ pediatricians. Two hundred thirty-nine cases were compared with 854 controls. Odds ratios for various infant and maternal factors were estimated. Results Cases had lower birth weights, were more often male or a twin, and had more relatives with craniofacial malformations or hearing loss than controls. Case mothers had lower family incomes, had a lower body mass index, had more vaginal bleeding in the second trimester, and were more likely to have had a spontaneous abortion in a previous pregnancy. Conclusions Nonmodifiable factors (age and parity) were not associated with hemifacial microsomia risk. Factors that are related to poverty (low family income, late recognition of pregnancy, and low body mass index) are associated with an increase in risk. High risk estimates for multiple pregnancies and second-trimester vaginal bleeding suggest a vascular etiology.

Association Between Adolescent Body Mass Index and Adulthood Smoking

2018 ◽  
Vol 21 (12) ◽  
pp. 1629-1635 ◽  
Author(s):  
Michael Fang
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Cigarette Smoking ◽  
Body Mass ◽  
Smoking Behavior ◽  
The United States ◽  
Adolescent Females ◽  
Overweight And Obesity ◽  
The Past

Abstract Introduction Studies increasingly find a prospective association between adolescent weight status and adverse physical health outcomes. However, less is known about the long-term consequences of adolescent body weight on the adoption of health-risk behaviors. This study sought to determine whether adolescent body mass index (BMI) was associated with cigarette smoking in adulthood. Methods Six thousand six hundred eighty-three nonsmoking adolescents were interviewed at baseline (1996, age 11–20) and at follow-up (2008, age 24–32) as part of the National Longitudinal Survey of Adolescent Health. Logistic and fractional regression models tested the association between adolescent BMI and smoking status and frequency in adulthood. Respondent weight and height were measured at baseline and converted into age and sex-specific BMI z-scores. Being a smoker was defined as smoking at least once in the past 30 days, while smoking frequency was defined as the proportion of days smoked over the past 30 days. Both outcomes were measured at follow-up. Results Adolescent BMI was positively associated with the transition from nonsmoking to smoking 12 years later for women but not men. Adolescent BMI was also positively associated with smoking frequency among women smokers. Both associations persisted after adjusting for established risk factors and were robust to sensitivity analyses. Conclusions Adolescent BMI was strongly associated with increased cigarette smoking behavior in adulthood for women, even after adjusting for important risk factors. Implications Using a large, nationally representative sample, this study found that adolescent BMI was positively associated with smoking behavior during adulthood for women but not men. These results have potentially important public health implications for future smoking rates in the United States, as the prevalence of overweight and obesity among US adolescent females continues to grow. Thus, it may be important for smoking prevention interventions to prioritize overweight adolescent females moving forward.

scholarly journals Assessing Indicators of Central Obesity as Hypertensive Risk Factors

2012 ◽  
Vol 1 (2) ◽  
pp. 11-18
Author(s):  
Alexis Dimitrios Stamatikos ◽  
Farzad Deyhim
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Risk Factor ◽  
Body Mass ◽  
Central Obesity ◽  
Sodium Intake ◽  
The United States ◽  
Left Ventricular ◽  
Health Concern ◽  
Heavy Alcohol Consumption

Hypertension, colloquially known as high blood pressure, is a severe public health concern in the United States.  Nearly one in three American adults aged 20 or over suffers from hypertension.  Hypertension may lead to left ventricular hypertrophy, heart failure, myocardial infarction, cerebral vascular accident, retinopathy, and renal failure. Risk factors for hypertension are numerous and include age, gender, ethnicity, sedentary lifestyle, excessive sodium intake, smoking, diabetes, heavy alcohol consumption, and recreational drug abuse. One of the most familiar markers used as a risk factor for hypertension is obesity based on body mass index. However, while body mass index is easy and inexpensive to apply, it has disadvantages and may not be the best suited marker for certain populations. A better predicting marker for hypertension instead of body mass index may be to measure or estimate intra-abdominal adiposity, commonly known as visceral fat. The clinical name of excessive amounts of adipose tissue around the midsection is central obesity. There are many techniques and procedures to evaluate central obesity, ranging from taking simple measurements and performing straightforward calculations, to utilizing high technologically advanced and expensive equipment. The purpose of this review is to thoroughly assess the rationality of employing central obesity as a risk factor for hypertension and to analyze which diagnostic tests and criteria, if any, are superior compared to others during the testing of both general and special populations.

scholarly journals American Indian, Alaska Native, Native Hawaiian, and Pacific Islander Children’s Body Mass Index: Diminished Returns of Parental Education and Family Income

2020 ◽  
Vol 5 (1) ◽  
pp. p64
Author(s):  
Shervin Assari
Keyword(s):  
Body Mass Index ◽  
American Indian ◽  
Body Mass ◽  
Alaska Native ◽  
Parental Education ◽  
Family Income ◽  
Native Hawaiian ◽  
Pacific Islander ◽  
The United States ◽  
Future Research

Background: High socioeconomic status (SES) is associated with several health-related outcomes, such as obesity and body mass index (BMI). However, we do not know whether SES is associated differently with children’s BMI from American Indian and Alaska Native and Native Hawaiian and Pacific Islander (AIAN/NHPI) families when compared to non-Hispanic White (NHW) families. Aim: To compare AIAN/NHPI and NHW families for associations between parental education, family income, and children’s BMI in the United States (U.S). Methods: This cross-sectional study used the Adolescent Brain Cognitive Development (ABCD) study. Participants (n = 8580) included 63 AIAN/NHPI and 8517 NHW children between ages 9 and 10. The independent variables were parental education and family income. The primary outcome was BMI. Race was the moderator. Age, sex, and family structure were covariates. Mixed-effects regression models were used for data analysis. Results: In the pooled sample, higher parental education and family income were associated with lower children’s BMI. We found interactions between race and parental education and family income indicating weaker associations between parental education and family income and children’s BMI in AIAN/NHPI families than in NHW families. Conclusion: The salience of parental education and family income as social determinants of children’s BMI is diminished for AIAN/NHPI families than NHW families. As a result, AIAN/NHPIs children with high SES remain at risk for high BMI, while high-SES NHW children show the lowest BMI. Future research should test if obesogenic environments, food options, and physical activity-friendly neighborhoods can explain higher-than-expected BMI in high-SES AIAN/NHPI children. In other terms, more research is needed to understand if residential segregation, discrimination, and historical trauma explain the observed differences in the social patterning of childhood BMI in AIAN/NHPI and NHW communities.

scholarly journals Incidence and Risk Factors for Perioperative Adverse Respiratory Events in Children Who Are Obese

2008 ◽  
Vol 108 (3) ◽  
pp. 375-380 ◽  
Author(s):  
Alan R. Tait ◽  
Terri Voepel-Lewis ◽  
Constance Burke ◽  
Amy Kostrzewa ◽  
Ian Lewis
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Sleep Apnea ◽  
Adverse Events ◽  
Body Mass ◽  
The United States ◽  
Normal Weight ◽  
Obese Children ◽  
Respiratory Events ◽  
Adverse Respiratory Events

Background Consistent with the increasing prevalence of obesity in the United States and many countries worldwide, anesthesiologists are now presented with a greater number of adult and pediatric patients who are significantly overweight. This prospective study was designed to examine the relation between age-adjusted body mass index, preoperative comorbidities, and perioperative outcome in children. Methods Children aged 2-18 yr undergoing noncardiac elective procedures were classified as overweight or obese based on their age- and sex-adjusted body mass index. Information was elicited regarding patient demographics, presence of comorbidities, and anesthetic technique. Data regarding the incidence and severity of perioperative adverse events were collected prospectively. Results Two thousand twenty-five children comprised the sample (1,380 normal weight, 351 overweight, and 294 obese). Obese children had a significantly higher prevalence of comorbidities than nonobese children, including asthma, hypertension, sleep apnea, and type II diabetes. Furthermore, obese children had a higher incidence of difficult mask ventilation, airway obstruction, major oxygen desaturation (>10% of baseline), and overall critical respiratory adverse events. Logistic regression analysis revealed several risk factors for adverse events, including procedures involving the airway, obesity, age younger than 10 yr, and a history of obstructive sleep apnea. Conclusions These results suggest that children presenting for elective surgical procedures who are obese have a greater prevalence of preexisting comorbid medical conditions and an increased incidence of perioperative adverse respiratory events compared with normal-weight children. Identification and awareness of risk factors for perioperative complications will be important in optimizing the anesthetic management of these children.

The Relation of Body Mass Index to Biochemical Parameters and Profile of Heart Failure

2018 ◽  
Vol 69 (7) ◽  
pp. 1673-1677
Author(s):  
Viviana Aursulesei ◽  
Andrei Manta ◽  
Razan Al Namat ◽  
Monica Hugianu ◽  
Angela Maria Moloce ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Body Mass Index ◽  
Body Mass ◽  
Patient Selection ◽  
Biochemical Parameters ◽  
Obesity Paradox ◽  
Lipid Levels ◽  
Randomized Control ◽  
Selection Parameters

The bidirectional relation between body mass index (BMI) and heart failure (HF) is complex and not fully understood. The obesity paradox phenomena is controversial and related to patient selection, parameters used for defining abnormal weight, characteristics of HF. Our study sustain the importance of controlling risk factors, in particular plasma glucose, lipid levels, as well as hypertension in patients with HF and BMI over 25 kg/m2. Also, in contrast to the randomized control studies our results can only partially support data related to obesity paradox phenomena.

scholarly journals Cardio-Metabolic Risk Factors in Scottish South Asian and Caucasian Youth

2021 ◽  
Vol 18 (9) ◽  
pp. 4667
Author(s):  
Meizi Wang ◽  
Jianhua Ying ◽  
Ukadike Chris Ugbolue ◽  
Duncan S. Buchan ◽  
Yaodong Gu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
South Asian ◽  
Metabolic Risk Factors ◽  
Individual Risk ◽  
Metabolic Risk ◽  
Asian Adolescents ◽  
Individual Risk Factors

(1) Background: Scotland has one of the highest rates of obesity in the Western World, it is well established that poor weight profiles, and particularly abdominal obesity, is strongly associated with Type II diabetes and cardiovascular diseases. Whether these associations are apparent in ethnic population groups in Scotland is unclear. The purpose of this study was to examine the associations between different measures of fatness with clustered cardio metabolic risk factors between Scottish South Asian adolescents and Scottish Caucasian adolescents; (2) Methods: A sample of 208 Caucasian adolescents and 52 South Asian adolescents participated in this study. Stature, waist circumference, body mass index, blood pressure, physical activity, and cardiovascular disease (CVD) risk were measured; (3) Results: Significant, partial correlations in the South Asian cohort between body mass index (BMI) and individual risk factors were generally moderate. However, correlations between Waist circumference (WC) and individual risk factors were significant and strong. In the Caucasian cohort, a significant yet weak correlation between WC and total cholesterol (TG) was noted although no other associations were evident for either WC or BMI. Multiple regression analysis revealed that both BMI and WC were positively associated with CCR (p < 0.01) in the South Asian group and with the additional adjustment of either WC or BMI, the independent associations with clustered cardio-metabolic risk (CCR) remained significant (p < 0.005); (4) Conclusions: No positive relationships were found between BMI, WC, and CCR in the Caucasian group. Strong and significant associations between measures of fatness and metabolic risk were evident in Scottish South Asian adolescents.

Short-Term Outcomes Following Removal of Infected Hernia Mesh

2021 ◽  
pp. 000313482110241
Author(s):  
Christine Tung ◽  
Junko Ozao-Choy ◽  
Dennis Y. Kim ◽  
Christian de Virgilio ◽  
Ashkan Moazzez
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Logistic Regression ◽  
Body Mass ◽  
Smoking History ◽  
Multivariate Logistic Regression ◽  
Short Term ◽  
Mesh Removal ◽  
Mesh Placement ◽  
Infected Mesh

There are limited studies regarding outcomes of replacing an infected mesh with another mesh. We reviewed short-term outcomes following infected mesh removal and whether placement of new mesh is associated with worse outcomes. Patients who underwent hernia repair with infected mesh removal were identified from 2005 to 2018 American College of Surgeons-National Surgical Quality Improvement Program database. They were divided into new mesh (Mesh+) or no mesh (Mesh-) groups. Bivariate and multivariate logistic regression analyses were used to compare morbidity between the two groups and to identify associated risk factors. Of 1660 patients, 49.3% received new mesh, with higher morbidity in the Mesh+ (35.9% vs. 30.3%; P = .016), but without higher rates of surgical site infection (SSI) (21.3% vs. 19.7%; P = .465). Mesh+ had higher rates of acute kidney injury (1.3% vs. .4%; P = .028), UTI (3.1% vs. 1.3%, P = .014), ventilator dependence (4.9% vs. 2.4%; P = .006), and longer LOS (8.6 vs. 7 days, P < .001). Multivariate logistic regression showed new mesh placement (OR: 1.41; 95% CI: 1.07-1.85; P = .014), body mass index (OR: 1.02; 95% CI: 1.00-1.03; P = .022), and smoking (OR: 1.43; 95% CI: 1.05-1.95; P = .025) as risk factors independently associated with increased morbidity. New mesh placement at time of infected mesh removal is associated with increased morbidity but not with SSI. Body mass index and smoking history continue to contribute to postoperative morbidity during subsequent operations for complications.

Body phenotypes and sexual maturation in Brazilian and US adolescents: evidence for a change in body mass index Category

2020 ◽  
pp. 1-26
Author(s):  
Jéssica Cumpian Silva ◽  
Ana Elisa Madalena Rinaldi ◽  
Francisco de Assis Guedes Vasconcelos ◽  
Maria Alice Altenburg Assis ◽  
Camila Medeiros Mazzeti ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Composition ◽  
Body Mass ◽  
Phase Angle ◽  
Sexual Maturation ◽  
Biochemical Parameters ◽  
Pubertal Development ◽  
The United States ◽  
Pubic Hair ◽  
Cholesterol Ratio

ABSTRACT Objective: Our study aimed to describe body phenotypes (BP) estimated by multivariate analysis and their association with body mass. Design: Body phenotypes were defined based on demographic variables, anthropometric data (body mass, height, skinfolds and circumferences), body composition (phase angle measured by bioelectrical impedance analysis), biochemical parameters (triglycerides, glucose, total cholesterol ratio/Low Density Lipoproteins (LDL), haemoglobin and sexual maturation (pubic hair and breasts or gonads). Analysis of variance (ANOVA) was performed to verify the differences between skin colour and the stages of pubertal development, body phenotypes, body composition, anthropometric, and biochemical variables. Setting: Cities of São Paulo-SP, Piracicaba-SP and Florianópolis-SC from Brazil and the United States. Participants: 9269 adolescents aged between 10 to 15 years old. Results: The composition of BP was similar in all surveys, which are: BP1 was composed by skinfolds, body mass and circumferences variables; BP2 by pubic hair, breast in girls or gonad in boys, height and age; BP3 by cholesterol, triglycerides and glucose; and BP4 by phase angle, haemoglobin and glucose (negative loading). There was a strong correlation (r = 0.9, p <0.001) between BP1 and body mass index. Conclusion: We highlighted independence observed between biochemical parameters, anthropometry, body composition and sexual maturation. BP may support the calculation of scores for diagnosis of obesity based on anthropometric variables and overcome ambiguity in the isolated use of body mass index.

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