Gender and Age-Related Differences in Patients with the Metabolic Syndrome in A Highly Endogamous Population.

The objective of the study was to examine the differences in gender and age prevalences of metabolic syndrome (MetS) among adult Qatari population according to the revised criteria of NCEP ATP III and IDF, assess which component contributed to the higher prevalence of the MetS and identify the characteristics of the subjects with MetS. The study was designed as a cross-sectional study. The survey was carried out in urban and semi-urban primary health care centers. The survey was conducted in the period from January 2007 to July 2008 among Qatari nationals above 20 years of age. Of the 1536 subjects who were approached to particípate in the study, 1222 (79.6%) gave their consent. Face to face interviews were conducted using a structured questionnaire followed by laboratory tests. MetS was defined using the National Cholesterol Education Program - Third Adult Treatment Panel (ATP III) as well as the International Diabetes Federation (IDF). The overall prevalence of MetS in studied subjects was 26.7% and 33.9% according to ATPIII and IDF (p<0.001) criteria respectively. The prevalence of MetS by both definitions peaked in the 30-39 years age group among males, and the 40-49 years age group among females. The greatest number of males with MetS were university educated; while the greatest number of females with MetS were either illiterate or had a primary school education. The prevalence of MetS was higher among females. Among the components of MetS, the prevalence of central obesity was significantly higher in studied subjects. The overall prevalence of MetS and its components according to IDF criteria was higher in studied subjects than the estimates given by the ATPIII criteria. Overall, the prevalence of the metabolic syndrome in the State of Qatar is about 10-15% higher than in most developed countries, with generally higher prevalence rates for women. Preventive strategies will require identifying socio-demographic factors and addressing modifiable risk behaviours, including lack of physical activity, and dietary intake.

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Associations of n-3 Fatty Acids and Fish Consumption with the Metabolic Syndrome in College Students (P18-022-19)

Current Developments in Nutrition ◽

10.1093/cdn/nzz039.p18-022-19 ◽

2019 ◽

Vol 3 (Supplement_1) ◽

Author(s):

Nicole Karazurna ◽

Caitlin Porter ◽

Jesse Stabile Morrell ◽

Sherman Bigornia

Keyword(s):

Risk Factors ◽

College Students ◽

Metabolic Syndrome ◽

Young Adults ◽

Fish Consumption ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

The Metabolic Syndrome ◽

Age Related

Abstract Objectives Evidence suggests that omega-3 fatty acid (n-3 FA) and fish consumption may reduce the risk of the metabolic syndrome (MetS) in older adults. We previously reported that MetS components are prevalent among college students. Identifying modifiable risk factors of developing MetS and its components in young adults will inform potential targets to reduce the risk of age-related health conditions. Our objectives were to measure the cross-sectional impacts of n-3 FA and fish consumption on ≥2 or ≥3 MetS criteria and individual criteria among college students. Methods The College Health and Nutrition Assessment Survey is an on-going cross-sectional study at a public New England college. We examined data from Jan 2008 – May 2017. After excluding those with missing data our final sample size was n = 4271 for n-3 FA & n = 2072 for fish intake analyses. Diet was assessed by a 3 day food record; MetS criteria were collected in fasted state. We expressed n-3 FAs as g/1000 kcals/d. Servings of fish/week was obtained via an online survey. Individuals were categorized as consuming ≥ 2 servings/week or not. MetS was defined as meeting ≥ 3 criteria: elevated glucose, triglycerides, blood pressure, waist circumference, and low HDL. Analyses were conducted by logistic regression. Results The average n-3 FA intake was 0.4 g/1000 kcal/d ± 0.25 & 40% consumed ≥ 2 servings of fish/week. Prevalence estimates for meeting ≥ 2 criteria was 18.8% and 4.8% for MetS. In sex- and energy- adjusted models, n-3 FA consumption was inversely associated with MetS (OR = 0.38; 95%CI: 0.20, 0.71) and ≥2 MetS criteria (OR = 0.67; 95%CI: 0.49, 0.91). Associations were no longer significant after considering additional confounders. Fish consumption was not significantly associated with MetS or ≥2 criteria in any model. Further n-3 FAs and fish consumption was not associated with any individual MetS criteria. Conclusions In this cross-sectional study among college students, n-3 FA and fish consumption were not significantly associated with MetS outcomes. Further research is needed in this population using longitudinal study designs to understand long-term impact of n-3 consumption on the development of MetS and associated cardio metabolic risk factors in young adults. Funding Sources New Hampshire Agriculture Experiment Station and USDA National Institute of Food and Agriculture Hatch Project 1010738.

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Prevalence of Metabolic Syndrome among Border Guard Bangladesh Personnel

Journal of Armed Forces Medical College Bangladesh ◽

10.3329/jafmc.v14i2.45883 ◽

2020 ◽

Vol 14 (2) ◽

pp. 97-100

Author(s):

Md Abdul Wahab ◽

Md Mustafizur Rahman ◽

Md Abdur Razzak ◽

Md Habibur Rahman ◽

Mimi Parvin ◽

...

Keyword(s):

Metabolic Syndrome ◽

International Diabetes Federation ◽

Armed Forces ◽

Cross Sectional Study ◽

Age Group ◽

Metabolic Abnormalities ◽

Sectional Study ◽

Ethnic Population ◽

Cross Sectional ◽

Medical College

Introduction: Metabolic syndrome (MetS) is a multifaceted syndrome comprises a cluster of metabolic abnormalities including hypertension, central obesity, insulin resistance, dyslipidemia, and is strongly associated with developing diabetes mellitus and cardiovascular diseases. Prevalence of MetS differs in different ethnic population by using different definition. Objectives: To determine the prevalence of the MetS and its component risk factors among Border Guard Bangladesh (BGB) personnel working in Chattagram Hill Tract (CHT). Materials & Methods: This descriptive cross-sectional study was conducted from October 2016 to February 2018 among 1455 male BGB personnel aged between 40 to 59 years and working in CHT of Bangladesh. Study subjects were selected at BGB hospital, Guimara, Khagrachari. The new International Diabetes Federation (IDF) guidelines were used to identify MetS. Detail history, clinical examination, anthropometry and blood pressure (BP) were measured and fasting plasma glucose (FPG) and lipid profile were assessed. Results: Among the 1455 respondents’ BMI, waist circumference, systolic and diastolic BP were found more than normal in 34.1, 37.7, 16.4% and 12.3% respectively. Biochemical parameters including FPG, TC, TG, and LDL-C was raised in 28.7%, 49.8%, 52.2% and 37.7% of respondents respectively. HDL-C was found decreased in 26.9% respondents. Age wise prevalence of MetS for age group 40-44, 45-49, 50-54 and 55- 59 years were found 21.3%, 21.7%, 24.1% and 26.1% of the respondents respectively. The overall prevalence of MetS was found 22.4%. Conclusion: The prevalence of the MetS in BGB personnel was found 22.4%. Appropriate measure should be taken to lower the MetS cases. Journal of Armed Forces Medical College Bangladesh Vol.14 (2) 2018: 97-100

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Prevalence of Metabolic Syndrome and Its Components in Adults with Central Obesity at Janakpur Zone, Nepal

Journal of Nepal Health Research Council ◽

10.33314/jnhrc.v18i4.2890 ◽

2021 ◽

Vol 18 (4) ◽

pp. 681-685

Author(s):

Birendra Kumar Jha ◽

Mingma Lhamu Sherpa ◽

Binod Kumar Dahal ◽

Jitendra Kumar Singh

Keyword(s):

Risk Factors ◽

Metabolic Syndrome ◽

Central Obesity ◽

International Diabetes Federation ◽

Cross Sectional Study ◽

High Density Lipoproteins ◽

Cluster Sampling ◽

Cross Sectional ◽

The Metabolic Syndrome

Background: Urbanization, surplus energy uptake, decreased physical activities are general risk factors of metabolic syndrome However, it’s status, and associated components remain unexplored in the Terai region of Nepal. This study evaluated the prevalence of metabolic syndrome and its components among adults with central obesity of Terai region of Nepal using International Diabetes Federation criteria.Methods: Community based cross-sectional study was conducted in three Terai districts of Janakpur Zone, Nepal. A total of 378 adults having central obesity were selected using cluster sampling by camp approach. Interview, physical and clinical examination, measurement of fasting blood sugar, and lipid profile were conducted for all participants. The prevalence of metabolic syndrome and its components with 95% CI were estimated.Results: The metabolic syndrome prevalence was 74.9% (95% CI:70.2-79.2%), with no significant differences between male (77.7%, 95% CI:71.0-83.5%) and female (72.2%, 95% CI: 65.2-78.3%). The most common factors observed were low high density lipoproteins with highly significant differences between male (77.7%, 95% CI:71.0-83.5%)) and female (90.2%, 95% CI: 85.094.0%-; p=0.001) and hypertriglyceridemia with significant differences between male (57.6%, 95% CI: 50.1-64.5%) and female (46.9%, 95% CI: 39.7-54.2%; p=0.037). Conclusions: Higher prevalence of metabolic syndrome and its risk factors in Janakpur of Nepal likely suggest lack of awareness and health promotion activities for metabolic syndrome and indicate an urgency for a public health program to maintain quality of life. Keywords: Metabolic syndrome; Nepal; prevalence; risk factors; terai

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Hyperuricemia is associated with metabolic syndrome in the community very elderly in Chengdu

Scientific Reports ◽

10.1038/s41598-020-65605-w ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Gang Huang ◽

Junbo Xu ◽

Tingjie Zhang ◽

Lin Cai ◽

Hanxiong Liu ◽

...

Keyword(s):

Metabolic Syndrome ◽

Logistic Regression ◽

Metabolic Diseases ◽

International Diabetes Federation ◽

Density Lipoprotein ◽

Cross Sectional Study ◽

Very Elderly ◽

Cross Sectional ◽

The Metabolic Syndrome ◽

Elderly Chinese

Abstract Hyperuricemia is a risk factor for cardiovascular metabolic diseases. However, in the very elderly, the relationship between hyperuricemia and the metabolic syndrome (MetS) is not yet clear. This study was aimed to investigate the potential association between hyperuricemia and MetS in community very elderly in Chengdu. In this cross-sectional study, 1056 very elderly in the community were enrolled. Serum uric acid (SUA), fast plasma glucose, triglycerides and high–density lipoprotein cholesterol were measured, and then MetS components were calculated. Logistic regression models were used to explore risk factors for MetS in the very elderly. Finally, 1035 participants were included in analysis whose ages ranged between 80 and 100 with a mean age of 83.6 ± 3.4 years. The mean SUA level was 356.2 ± 95.0 µmol/L. The estimated prevalence of MetS in the very elderly was 25.0% vs. 21.6% (international diabetes federation (IDF) criteria vs. Chinese guideline), which was significantly higher for women (IDF criteria:17.3% in men vs 33.6% in women, p < 0.001). Logistic regression has found that participants with hyperuricemia (SUA level > 416 µmol/L in men and > 357 µmol/L in women) had a higher risk (IDF criteria: odds ratio (OR): 2.136, 95% confidence interval(CI): 1.525–2.993, p < 0.001. Chinese guideline: OR: 1.769, 95%CI: 1.249–2.503, p = 0.001) of MetS in very elderly Chinese. MetS is common in the community of very elderly Chinese in Chengdu. Hyperuricemia is associated with MetS in general very elderly and lifestyle changing should also be considered in the very elderly.

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Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study

BMC Endocrine Disorders ◽

10.1186/1472-6823-13-47 ◽

2013 ◽

Vol 13 (1) ◽

Cited By ~ 208

Author(s):

Pilar Gayoso-Diz ◽

Alfonso Otero-González ◽

María Xosé Rodriguez-Alvarez ◽

Francisco Gude ◽

Fernando García ◽

...

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

Adult Population ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Population Effect ◽

The Metabolic Syndrome ◽

Gender And Age ◽

General Adult Population

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Influence of 5-HTR2C Polymorphisms on Metabolic Syndromes in Thai Schizophrenia Patients

European Psychiatry ◽

10.1016/j.eurpsy.2017.01.2057 ◽

2017 ◽

Vol 41 (S1) ◽

pp. S168-S168

Author(s):

A. Puangpetch ◽

C. Na Nakorn ◽

W. Unaharassamee ◽

C. Sukasem

Keyword(s):

Metabolic Syndrome ◽

International Diabetes Federation ◽

Cross Sectional Study ◽

Nucleotide Polymorphisms ◽

Cross Sectional ◽

Female Patients ◽

The Metabolic Syndrome ◽

Significant Difference ◽

Male Patients ◽

Competing Interest

IntroductionMetabolic syndrome is a significant problem in the schizophrenia patients. Previous research demonstrated that single nucleotide polymorphisms in the serotonin 2C receptor (5HTR2C) genes are associated with metabolic syndrome related to schizophrenia patients taking atypical anti-psychotic drugs. This study aimed to investigate whether the effect of 3 SNPs in 5HTR2C gene on the presence of the metabolic syndrome in Thai schizophrenia patients.MethodWe conducted a cross-sectional study and 154 patients were recruited. The schizophrenia patients were identified from a diagnostic and statistical manual of mental disorders, 4th edition, (DSM-IV) and criterion and determined the metabolic syndrome according to the 2005 international diabetes federation (IDF) Asia criteria. Patients were genotyped for the 5HTR2C rs51,8147, rs126,881,02, rs128,367,71 polymorphisms.ResultsThe preliminary analysis from 154 patients showed the metabolic syndrome prevalence was 38.73%, with 46.50% in male and 53.48% in female patients. The results showed that the patients who have heterozygous and homozygous variant on 5HTR2C gene (rs518,147 and rs126,881,02) showed a significant difference in the presence of metabolic syndrome when compare with patients who carry homozygous wild type (P = 0.007), especially in male patients (P = 0.002). The association between 5HTR2C polymorphisms and metabolic syndrome was found in male patients but not found in female patients.ConclusionThese findings suggest that 5HTR2C genotypes are associated with the metabolic syndrome in patients taking atypical anti-psychotics. However, the metabolic syndrome results from the multigenetic effects. The further studies should focus on the other genes, which were involved in metabolic syndrome.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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HUBUNGAN PERILAKU SEDENTARI DENGAN SINDROM METABOLIK PADA PEKERJA

The Indonesian Journal of Public Health ◽

10.20473/ijph.v13i2.2018.145-157 ◽

2019 ◽

Vol 13 (2) ◽

pp. 145

Author(s):

Lailiyah Yusna Yusfita

Keyword(s):

Metabolic Syndrome ◽

Metabolic Diseases ◽

Sedentary Lifestyle ◽

International Diabetes Federation ◽

Hdl Cholesterol ◽

Simple Random Sampling ◽

Cross Sectional Study ◽

Cross Sectional ◽

The Metabolic Syndrome ◽

Chi Square Analysis

Sedentary lifestyle has been done by many workers either in the workplace, home, even on transportation. High sedentary lifestyle is a risk factor for metabolic syndrome among workers that cause of metabolic diseases such as Coronary Heart Disease, diabetes mellitus type 2, and Stroke. According to the International Diabetes Federation (IDF) in 2005, the metabolic syndrome is characterized by abdominal obesity plus at least 2 other positive components consisting of hypertriglycerides, low HDL cholesterol, hypertension, and hyperglycemia. This study is a cross sectional study to determine relationship of sedentary lifestyle with metabolic syndrome. 66 workers of 113 workers who performed Medical Check Up (MCU) at Prima Medika Laboratory Surabaya during November - December 2017 became a sample of this study. Sampling method was simple random sampling. The independent variables in this study were age, sex, and sedentary lifestyle. The dependent variable was metabolic syndrome. This study used Chi-square analysis to assess the relationship between independent variable and dependent variable. The results showed the prevalence of metabolic syndrome among workers was 43.9%. Of the 29 workers with metabolic syndrome, 26 workers had a sedentary lifestyle ≥ 6 hours per day with a median was 9.11 hours per day. There was a correlation between sedentary lifestyle ≥ 6 hours per day with metabolic syndrome (p = 0.000), whereas showed no association with metabolic syndrome between age (p = 0.058) and sex (p = 0.168). The conclusions of this study were sedentary ≥ 6 hours per day associated with metabolic syndrome among workers. Workers should reduce sedentary lifestyle by stretching, avoiding sitting too long while working, and increasing physical activity in the workplace.

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Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome

Journal of Medicine and Pharmacy ◽

10.34071/jmp.2019.6_7.10 ◽

2019 ◽

pp. 68-73

Author(s):

Trong Nghia Nguyen ◽

Thi Nhan Nguyen ◽

Thi Dua Dao

Keyword(s):

Metabolic Syndrome ◽

Medical Center ◽

Cross Sectional Study ◽

Control Group ◽

Cross Sectional ◽

Hydroxyvitamin D ◽

The Metabolic Syndrome ◽

25 Hydroxyvitamin D ◽

Key Words Metabolic Syndrome ◽

And Control

Background: The metabolic syndrome is a constellation of cardiometabolic risk factors that tend to cluster together in affected individuals more often than predicted by chance. The presence of the metabolic syndrome substantially increases the risk of developing type 2 diabetes and cardiovascular disease, and is associated with a range of adverse clinical outcomes, many of which are closely associated with aging. Current estimates suggest that approximately 20 - 25% of the world’s population is affected by the metabolic syndrome. The prevalence of the metabolic syndrome rises with age and more than 45% of people aged over 60 years have the metabolic syndrome. Recent studies show that low vitamin D status is very common in the world and this is a risk factor of metabolic syndrome. Objective: (1) Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome. (2) Cut off value of plasma 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Material and method: A cross-sectional study with control group on 318 adult subjects for health examinations at International Medical Center at Hue Central Hospital, including 139 subjects with metabolic syndrome and control group of 179 healthy subjects. Metabolic syndrome was defined according to the IDF, NHLBI, AHA, WHF, IAS, IASO (2009). Plasma hydroxyvitamin D concentration was measured using chemiluminescent microparticle immunoassay. Reciever operating characteristic (ROC) curve were generated to assess sensitivity and specificity for different cut off value of 25-hydroxyvitamin D concentration for predicting metabolic syndrome. Results: Plasma 25-hydroxyvitamin D concentration in subjects with metabolic syndrome was 26.4 ng/ml, incidence of plasma 25-hydroxyvitamin D deficiency (59.7%) was significantly higher than in control group (23.5%) (p < 0.001). The optimal cut off point for 25-OH-D concentration for predictor of metabolic syndrome as 26.4 ng/ml (AUC=0.657, sensitivity=53.4%, specificity=71.6%). Conclusion: In 139 subjects with metabolic syndrome, the plasma 25-hydroxyvitamin D concentration was 26.4 ng/ml and the incidence of 25-hydroxyvitamin D deficiency in the metabolic syndrome group was 59.7%. The optimal cut off point for plasma 25-hydroxyvitamin D concentration for predictor of metabolic syndrome as 26.4 ng/ml. Key words: Metabolic syndrome, 25-hydroxyvitamin D

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Metabolic Syndrome in HIV-patients in Antiretroviral Therapy

Current HIV Research ◽

10.2174/1570162x18666200609115615 ◽

2020 ◽

Vol 18 (6) ◽

pp. 388-395

Author(s):

Daniel Vargas-Pacherrez ◽

Helma P. Cotrim ◽

Leonardo Pires ◽

Vitor Cunha ◽

Vitor Coelho ◽

...

Keyword(s):

Metabolic Syndrome ◽

Antiretroviral Therapy ◽

International Diabetes Federation ◽

Cross Sectional Study ◽

People Living With Hiv ◽

Anthropometric Data ◽

Cross Sectional ◽

History Of ◽

Family History Of Hypertension ◽

Living With Hiv

Introduction: The global prevalence of metabolic syndrome (MS) among people living with HIV/AIDS varies from 20% to 33%. Objective: to estimate the prevalence of metabolic syndrome and associated factors in a group of HIV-infected patients on antiretroviral therapy. Methods: This is a cross-sectional study with HIV-infected patients from a reference center in Bahia, Brazil. We evaluated clinical, socio-demographic and anthropometric data. MS was defined according to the guidelines of International Diabetes Federation. Results: We evaluated 152 patients with mean age of 47.3±11.6 years, 59.2% male. The main comorbidities detected were diabetes (3.3%) hypertriglyceridemia (9.3%) and metabolic syndrome (MS,38.2%). Patients with MS were predominantly women (55.2% vs 31.9%; p=0.005), older [52.1 (10.4) vs 44.3 (11.3); p<0.001], and had overweight (74.1% vs 23.4%; p<0.001). After multivariate analysis MS remained associated with age (OR = 1.076; 95% CI: 1.030 – 1.125), female sex (OR = 2.452; 95% CI: 1.114 – 5.374) and family history of hypertension (OR = 3.678; 95% CI: 1.431 – 9.395). Conclusion: Almost half of the HIV-infected patients in Bahia presents with MS which seems to be driven by classical risk factors.

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