scholarly journals Simulation of Air Motion in Human Lungs during Breathing. Dynamics of Liquid Droplet Precipitation in the Case of Medicine Drug Aerosols

2021 ◽  
Vol 16 (2) ◽  
pp. 422-438
Author(s):  
A.E. Medvedev ◽  
P.S. Golysheva
Keyword(s):  
Respiratory Tract ◽  
Numerical Simulations ◽  
Cross Sections ◽  
Liquid Droplet ◽  
Air Flow ◽  
Bronchial Tree ◽  
Lung Pathology ◽  
Human Lungs ◽  
Wide Range ◽  
Medical Drug

The paper deals with numerical simulation of the air flow in the full human bronchial tree. In their previous studies, the authors developed an analytical model of the full human bronchial tree and a method of stage-by-stage computation of the respiratory tract. A possibility of using the proposed method for a wide range of problems of numerical simulations of the air flow in human lungs is analyzed. The following situations are considered: 1) steady inspiration (with different flow rates of air) for circular and “starry” cross sections of bronchi (“starry” cross sections models some lung pathology); 2) steady expiration; 3) unsteady inspiration; 4) precipitation of medical drug aerosol droplets in human bronchi. The results predicted by the proposed method are compared with results of other researchers and found to be in good agreement. In contrast to previous investigations, the air flow in the full (down to alveoli) bronchial tree is studied for the first time. It is shown that expiration requires a greater pressure difference (approximately by 30%) than inspiration. Numerical simulations of precipitation of medical drug aerosol droplets in the human respiratory tract show that aerosol droplets generated by a standard nebulizer do not reach the alveoli (the droplets settle down in the lower regions of the bronchi).

scholarly journals Investigation on the Nonconstant Behavior of a Vortex Flow Meter with Narrow Gauge Pipe via Conducting Measurements and Numerical Simulations

1970 ◽  
Vol 61 (3) ◽  
pp. 247
Author(s):  
Bence Fenyvesi ◽  
Csaba Horváth
Keyword(s):  
Numerical Simulations ◽  
Cross Sections ◽  
Flow Measurement ◽  
Vortex Flow ◽  
Volume Flow Rate ◽  
Volume Flow ◽  
Diagnostic Investigation ◽  
Number Range ◽  
Wide Range ◽  
The Given

Vortex shedding flowmeters can be used for a wide range of flow measurement applications with various kinds of fluids. The critical point in applying this method comes from the assumption that the Strouhal number is constant for the given Reynolds number range. In some cases – typically regarding flowmeters with narrow gauge pipes –, this assumption is only partially met, thus limiting the widespread use of these instruments in certain industrial appliances. The paper presents a diagnostic investigation on the effects of this nonconstant behavior. The method elaborated in this report can be applied to vortex flowmeters with narrow gauge pipes. In these instruments – usually due to the narrow cross-sections of the gauge pipe – measurement possibilities are limited, thus it is not possible for the user to determine the effects of the nonconstant behavior. To conduct these investigations, a calibration rig was designed and assembled. The presented diagnostic method combines measurements and numerical simulations. The results of the investigations can be used in the data processing phase, in order to reduce the uncertainty of the volume flow rate measured by vortex flowmeters.

URBAN FACADE GEOMETRY ON OUTDOOR COMFORT CONDITIONS: A REVIEW

2020 ◽  
Vol 4 (1) ◽  
pp. 45
Author(s):  
Elahe Mirabi ◽  
Nasrollahi Nazanin
Keyword(s):  
Thermal Comfort ◽  
Urban Areas ◽  
Natural Ventilation ◽  
Flow Behavior ◽  
Air Flow ◽  
Urban Geometry ◽  
Wide Range ◽  
Low Energy Buildings ◽  
Outdoor Comfort ◽  
Solar Access

<p>Designing urban facades is considered as a major factor influencing issues<br />such as natural ventilation of buildings and urban areas, radiations in the<br />urban canyon for designing low-energy buildings, cooling demand for<br />buildings in urban area, and thermal comfort in urban streets. However, so<br />far, most studies on urban topics have been focused on flat facades<br />without details of urban layouts. Hence, the effect of urban facades with<br />details such as the balcony and corbelling on thermal comfort conditions<br />and air flow behavior are discussed in this literature review. <strong>Aim</strong>: This<br />study was carried out to investigate the effective factors of urban facades,<br />including the effects of building configuration, geometry and urban<br />canyon’s orientation. <strong>Methodology and Results</strong>: According to the results,<br />the air flow behavior is affected by a wide range of factors such as wind<br />conditions, urban geometry and wind direction. Urban façade geometry<br />can change outdoor air flow pattern, thermal comfort and solar access.<br /><strong>Conclusion, significance and impact study</strong>: In particular, the geometry of<br />the facade, such as indentation and protrusion, has a significant effect on<br />the air flow and thermal behavior in urban facades and can enhance<br />outdoor comfort conditions. Also, Alternation in façade geometry can<br />affect pedestrians' comfort and buildings energy demands.</p>

OCCURRENCE OF THE RISKS FOR DEVELOPMENT OF RESPIRATORY DISEASES IN CHILDREN EXPOSED TO THE CHEMICAL FACTORS OF THE EXPOSURE OF ALUMINA REFINERY- ASSOCIATED BUSINESS ACTIVITY

2019 ◽  
pp. 42-47 ◽  
Author(s):  
M.A. Zemlianova ◽  
I.V. Tikhonova
Keyword(s):  
Respiratory Tract ◽  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Allergic Inflammation ◽  
Respiratory Morbidity ◽  
Upper Respiratory Tract ◽  
Negative Effects ◽  
Wide Range ◽  
Chemical Factors ◽  
Chronic Lymphoproliferative Diseases

Alumina refineries are among the leading sources of atmospheric air pollution with a wide range of pollutants hazardous to human respiratory organs. It is relevant to study and evaluate the occurrence of the risks for development of respiratory diseases in children living in the area affected by the emission components of an alumina refinery. We assessed air quality of the area under observation and comparison according to monitoring observations, risk of non-carcinogenic effects from the respiratory organs. The content of chemicals in the blood and urine adequate to risk factors was quantified. The structure of individual groups of respiratory diseases was analyzed. The causal relationships of violations of laboratory parameters with an increased content of chemicals in biological media were evaluated. It was found that an aerogenic exposure of chemical pollutants is formed on the territory with the production of metallurgical alumina. It determines the risk for development of respiratory diseases, exceeding an acceptable level up to 49.9 times. In the exposed children, the content of manganese, chromium, nickel, copper, xylenes, formaldehyde and aluminum, fluoride ion in the urine was increased to 4.2 times in relation to the indices in the comparison group. A high level of additional respiratory morbidity(1.8 times) was revealed. Chronic lymphoproliferative diseases of the nasopharynx and inflammatory diseases of the upper respiratory tract (up to 6.6 times more often), inflammatory diseases with a predominance of the mechanism of allergic inflammation ( up to 2.1 times more often)are more often detected in the framework of the respiratory diseases. Negative effects on the part of the respiratory system in the form of activation of antioxidant processes, the development of an inflammatory reaction, local, general and specific sensitization of the respiratory tract were established. It confirms the occurrence of the risks for the development of respiratory diseases in children in the exposure area of the chemical factors of alumina refinery-associated economic activity.

Nitrogen Removal from Anaerobically-Treated Leachate

1984 ◽  
Vol 19 (1) ◽  
pp. 87-100
Author(s):  
D. Prasad ◽  
J.G. Henry ◽  
P. Elefsiniotis
Keyword(s):  
Nitrogen Removal ◽  
Air Flow ◽  
Operating Conditions ◽  
Air Flow Rate ◽  
Flow Rates ◽  
Anaerobic Filter ◽  
Ph Values ◽  
Wide Range ◽  
Ammonia Desorption ◽  
Effects Of Ph

Abstract Laboratory studies were conducted to demonstrate the effectiveness of diffused aeration for the removal of ammonia from the effluent of an anaerobic filter treating leachate. The effects of pH, temperature and air flow on the process were studied. The coefficient of desorption of ammonia, KD for the anaerobic filter effluent (TKN 75 mg/L with NH3-N 88%) was determined at pH values of 9, 10 and 11, temperatures of 10, 15, 20, 30 and 35°C, and air flow rates of 50, 120, and 190 cm3/sec/L. Results indicated that nitrogen removal from the effluent of anaerobic filters by ammonia desorption was feasible. Removals exceeding 90% were obtained with 8 hours aeration at pH of 10, a temperature of 20°C, and an air flow rate of 190 cm3/sec/L. Ammonia desorption coefficients, KD, determined at other temperatures and air flow rates can be used to predict ammonia removals under a wide range of operating conditions.

scholarly journals Bilayer ventilated labyrinthine metasurfaces with high sound absorption and tunable bandwidth

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Jiayuan Du ◽  
Yuezhou Luo ◽  
Xinyu Zhao ◽  
Xiaodong Sun ◽  
Yanan Song ◽  
...  
Keyword(s):  
Sound Absorption ◽  
Air Flow ◽  
Single Layer ◽  
Sound Waves ◽  
Acoustic Metamaterials ◽  
Sound Barrier ◽  
Free Air ◽  
Relative Bandwidth ◽  
Wide Range ◽  
High Sound

AbstractThe recent advent of acoustic metamaterials offers unprecedented opportunities for sound controlling in various occasions, whereas it remains a challenge to attain broadband high sound absorption and free air flow simultaneously. Here, we demonstrated, both theoretically and experimentally, that this problem can be overcome by using a bilayer ventilated labyrinthine metasurface. By altering the spacing between two constituent single-layer metasurfaces and adopting asymmetric losses in them, near-perfect (98.6%) absorption is achieved at resonant frequency for sound waves incident from the front. The relative bandwidth of absorption peak can be tuned in a wide range (from 12% to 80%) by adjusting the open area ratio of the structure. For sound waves from the back, the bilayer metasurface still serves as a sound barrier with low transmission. Our results present a strategy to realize high sound absorption and free air flow simultaneously, and could find applications in building acoustics and noise remediation.

scholarly journals Vector boson fusion at multi-TeV muon colliders

2020 ◽  
Vol 2020 (9) ◽  
Author(s):  
Antonio Costantini ◽  
Federico De Lillo ◽  
Fabio Maltoni ◽  
Luca Mantani ◽  
Olivier Mattelaer ◽  
...  
Keyword(s):  
Cross Sections ◽  
Vector Boson ◽  
High Energy ◽  
New Physics ◽  
Vector Boson Fusion ◽  
Weak Boson ◽  
Wide Range ◽  
Lepton Colliders ◽  
Muon Colliders ◽  
New Phenomena

Abstract High-energy lepton colliders with a centre-of-mass energy in the multi-TeV range are currently considered among the most challenging and far-reaching future accelerator projects. Studies performed so far have mostly focused on the reach for new phenomena in lepton-antilepton annihilation channels. In this work we observe that starting from collider energies of a few TeV, electroweak (EW) vector boson fusion/scattering (VBF) at lepton colliders becomes the dominant production mode for all Standard Model processes relevant to studying the EW sector. In many cases we find that this also holds for new physics. We quantify the size and the growth of VBF cross sections with collider energy for a number of SM and new physics processes. By considering luminosity scenarios achievable at a muon collider, we conclude that such a machine would effectively be a “high-luminosity weak boson collider,” and subsequently offer a wide range of opportunities to precisely measure EW and Higgs couplings as well as discover new particles.

scholarly journals The Impact of Initial Conditions in N-Body Simulations of Debris Discs

2015 ◽  
Vol 32 ◽  
Author(s):  
E. Thilliez ◽  
S. T. Maddison
Keyword(s):  
Numerical Simulations ◽  
Initial Conditions ◽  
Parent Body ◽  
Dust Trapping ◽  
Physical Context ◽  
Disc Width ◽  
Wide Range ◽  
Belt Width ◽  
New Generation ◽  
The Impact

AbstractNumerical simulations are a crucial tool to understand the relationship between debris discs and planetary companions. As debris disc observations are now reaching unprecedented levels of precision over a wide range of wavelengths, an appropriate level of accuracy and consistency is required in numerical simulations to confidently interpret this new generation of observations. However, simulations throughout the literature have been conducted with various initial conditions often with little or no justification. In this paper, we aim to study the dependence on the initial conditions of N-body simulations modelling the interaction between a massive and eccentric planet on an exterior debris disc. To achieve this, we first classify three broad approaches used in the literature and provide some physical context for when each category should be used. We then run a series of N-body simulations, that include radiation forces acting on small grains, with varying initial conditions across the three categories. We test the influence of the initial parent body belt width, eccentricity, and alignment with the planet on the resulting debris disc structure and compare the final peak emission location, disc width and offset of synthetic disc images produced with a radiative transfer code. We also track the evolution of the forced eccentricity of the dust grains induced by the planet, as well as resonance dust trapping. We find that an initially broad parent body belt always results in a broader debris disc than an initially narrow parent body belt. While simulations with a parent body belt with low initial eccentricity (e ~ 0) and high initial eccentricity (0 < e < 0.3) resulted in similar broad discs, we find that purely secular forced initial conditions, where the initial disc eccentricity is set to the forced value and the disc is aligned with the planet, always result in a narrower disc. We conclude that broad debris discs can be modelled by using either a dynamically cold or dynamically warm parent belt, while in contrast eccentric narrow debris rings are reproduced using a secularly forced parent body belt.

Large Eddy Simulations of Staggered Parallel-Plate Flows

2005 ◽  
Author(s):  
M. V. Pham ◽  
F. Plourde ◽  
S. K. Doan
Keyword(s):  
Heat Transfer ◽  
Numerical Simulations ◽  
Heat Transfer Enhancement ◽  
Parallel Plate ◽  
Large Scale ◽  
Primary Objective ◽  
Transfer Enhancement ◽  
Turbulent Structures ◽  
Wide Range ◽  
Large Eddy

Heat transfer enhancement is a subject of major concern in numerous fields of industry and research. Having received undivided attention over the years, it is still studied worldwide. Given the exponential growth of computing power, large-scale numerical simulations are growing steadily more realistic, and it is now possible to obtain accurate time-dependent solutions with far fewer preliminary assumptions about the problems. As a result, an increasingly wide range of physics is now open for exploration. More specifically, it is time to take full advantage of large eddy simulation technique so as to describe heat transfer in staggered parallel-plate flows. In fact, from simple theory through experimental results, it has been demonstrated that surface interruption enhances heat transfer. Staggered parallel-plate geometries are of great potential interest, and yet many numerical works dedicated to them have been tarnished by excessively simple assumptions. That is to say, numerical simulations have generally hypothesized lengthwise periodicity, even though flows are not periodic; moreover, the LES technique has not been employed with sufficient frequency. Actually, our primary objective is to analyze turbulent influence with regard to heat transfers in staggered parallel-plate fin geometries. In order to do so, we have developed a LES code, and numerical results are compared with regard to several grid mesh resolutions. We have focused mainly upon identification of turbulent structures and their role in heat transfer enhancement. Another key point involves the distinct roles of boundary restart and the vortex shedding mechanism on heat transfer and friction factor.

Respiratory Mechanics of Sound Production in Chickens and Geese

1978 ◽  
Vol 72 (1) ◽  
pp. 229-250
Author(s):  
J. H. BRACKENBURY
Keyword(s):  
Respiratory System ◽  
Simultaneous Measurement ◽  
Sound Production ◽  
High Pressures ◽  
Respiratory Mechanics ◽  
Air Flow ◽  
Tracheal Pressure ◽  
Wide Range ◽  
Range Of Values ◽  
Respiratory Movements

1. Air flow, air sac pressure and tracheal pressure were measured in chickens and geese during a variety of different vocal and non-vocal activities. 2. Air flow and air sac pressure may rise to 500 ml s−1 and 60 cmH2O (6 103 N/m2) respectively during a crow in the chicken. During a sequence of honks in the goose the corresponding values are 650 ml s−1 and 25 cmH2O(2.5 × 10 3 N/m2) respectively. 3. The volume of air delivered through the respiratory system during a single crow is more than 400 ml, almost equivalent to the total volume of the lung air sac system. 4. The efficiency of the chicken syrinx as a sound producing instrument, estimated by comparing the sound energy radiated with the energy consumed in the expulsion of air during a crow, appears to be less than 2 %. 5. Cutting the paired sternotrachealis muscles had no effect on vocalization. 6. The measured rates of clucking, cheeping and honking in adult chickens, young chicks and adult geese respectively are comparable to the characteristic rates of panting in these animals. This points to a similarity in the nature of the respiratory movements involved in each case. 7. Simultaneous measurement of tracheal flow and pressure indicate that the glottis is capable of controlling air flow over a wide range of values in the presence of high pressures. During defaecation the valve is closed whilst during coughing it is wide open.

Microtremor measurements used to map thickness of soft sediments

1999 ◽  
Vol 89 (1) ◽  
pp. 250-259
Author(s):  
Malte Ibs-von Seht ◽  
Jürgen Wohlenberg
Keyword(s):  
Cross Sections ◽  
Vertical Component ◽  
Noise Spectrum ◽  
Main Peak ◽  
Spectral Ratios ◽  
Wide Range ◽  
Noise Measurements ◽  
Cover Thickness ◽  
Microtremor Measurements ◽  
Lower Rhine Embayment

Abstract The observations about the behavior of microtremor spectra presented here show that noise measurements can be used as a powerful tool to determine the thickness of soft cover layers. The most suitable method for this determination is Nakamura's technique, which is the ratio of the horizontal-component noise spectrum and that of the vertical component (H/V spectrum). The frequency of the main peak in these spectral ratios correlates well with the sediment thickness at the site. Using an extensive database of microtremor measurements carried out in the western Lower Rhine Embayment (Germany), it was possible to show that this correlation is clearly valid for a wide range of thickness, namely, from tens of meters to more than 1000 m. A simple formula was derived that, for the sediments to be found in the area investigated, directly calculates the cover thickness from the frequency of the main peak in the H/V spectrum. A comparison with calculated resonant frequencies suggests the relation derived from the noise measurements depending on the velocity depth function of the shear wave. Classical spectral ratios are shown to be strongly influenced by the noise level and are therefore less reliable in determining the resonant frequency of the subsoil. The practical relevance of the investigation is illustrated by means of cross sections, constructed from results of the microtremor analyses, which provide a convincing image of the surficial structure of the areas investigated.

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