scholarly journals Faster Response to High-Fat Diet in Body Mass Regulation from Lower Altitude Population in Eothenomys miletus from Hengduan Mountain Regions

2021 ◽  
Author(s):  
Gong Xue-na
Keyword(s):  
Body Mass ◽  
High Fat Diet ◽  
High Fat ◽  
Mountain Regions ◽  
Lower Altitude ◽  
Hengduan Mountain ◽  
Body Mass Regulation ◽  
Eothenomys Miletus

Comparative Study on Phenotypic Differences in Eothenomys Miletus Under Food Restriction and Refeeding Between Xianggelila and Jianchuan from Hengduan Mountain Regions

2019 ◽  
Author(s):  
Dong-min , Xiao-ying Ren, Wan-long Zhu, Hou ◽  
Xiao-ying Ren ◽  
Wan-long Zhu ◽  
Hao Zhang
Keyword(s):  
Phenotypic Plasticity ◽  
Food Intake ◽  
Body Mass ◽  
Food Restriction ◽  
Mountain Regions ◽  
Serum Leptin ◽  
Hengduan Mountain ◽  
Activity Behavior ◽  
Hypothalamic Neuropeptides ◽  
Eothenomys Miletus

Body mass regulation may be appeared regional differences, in order to investigate the physiological and behavioral changes in Eothenomys miletus from Shanggelila (XGLL) and Jianchuan (JC) under food restriction (FR) and refeeding (Re), body mass, food intake, resting metabolic rate (RMR), serum leptin levels, hypothalamic neuropeptides expression and activity behavior were measured. The results showed that areas and FR had significant effects on body mass, food intake, RMR, activity behavior, serum leptin levels, hypothalamic neuropeptides expression, masses of liver and small intestine in E. miletus. Body mass and serum leptin levels in XGLL were lower than that of JC, food intake, activity behavior, liver mass and RMR in XGLL were higher relative to in JC. All the indexes of the two areas of E. miletus can be restored to control levels after refeeding, showing phenotypic plasticity. In conclusion, physiological and behavioral characteristics illustrated that the influences of food and different regions on phenotypic plasticity, which had important significance for in-depth understanding of the survival and adaptation strategies of E. miletus in Hengduan mountain regions.

scholarly journals ALTERED BODY MASS REGULATION IN MALEmPeriodMUTANT MICE ON HIGH-FAT DIET

2010 ◽  
Vol 27 (6) ◽  
pp. 1317-1328 ◽  
Author(s):  
Robert Dallmann ◽  
David R. Weaver
Keyword(s):  
Body Mass ◽  
High Fat Diet ◽  
High Fat ◽  
Body Mass Regulation

scholarly journals Methionine restriction plus overload improves skeletal muscle and metabolic health in old mice on a high fat diet

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Anandini Swaminathan ◽  
Andrej Fokin ◽  
Tomas Venckūnas ◽  
Hans Degens
Keyword(s):  
Skeletal Muscle ◽  
Glucose Tolerance ◽  
Muscle Mass ◽  
Body Mass ◽  
High Fat Diet ◽  
Control Diet ◽  
Metabolic Health ◽  
High Fat ◽  
Methionine Restriction ◽  
Old Mice

AbstractMethionine restriction (MR) has been shown to reduce the age-induced inflammation. We examined the effect of MR (0.17% methionine, 10% kCal fat) and MR + high fat diet (HFD) (0.17% methionine, 45% kCal fat) on body mass, food intake, glucose tolerance, resting energy expenditure, hind limb muscle mass, denervation-induced atrophy and overload-induced hypertrophy in young and old mice. In old mice, MR and MR + HFD induced a decrease in body mass. Muscle mass per body mass was lower in old compared to young mice. MR restored some of the HFD-induced reduction in muscle oxidative capacity. The denervation-induced atrophy of the m. gastrocnemius was larger in animals on MR than on a control diet, irrespective of age. Old mice on MR had larger hypertrophy of m. plantaris. Irrespective of age, MR and MR + HFD had better glucose tolerance compared to the other groups. Young and old mice on MR + HFD had a higher resting VO2 per body mass than HFD group. Mice on MR and MR + HFD had a resting respiratory quotient closer to 0.70, irrespective of age, indicating an increased utilization of lipids. In conclusion, MR in combination with resistance training may improve skeletal muscle and metabolic health in old age even in the face of obesity.

scholarly journals Supplementation of a Fermented Soybean Extract Reduces Body Mass and Prevents Obesity in High Fat Diet-Induced C57BL/6J Obese Mice

2016 ◽  
Vol 21 (3) ◽  
pp. 187-196 ◽  
Author(s):  
Jae Yeon Lee ◽  
Adithan Aravinthan ◽  
Young Shik Park ◽  
Kyo Yeol Hwang ◽  
Su-Il Seong ◽  
...  
Keyword(s):  
Body Mass ◽  
High Fat Diet ◽  
Obese Mice ◽  
High Fat ◽  
Fermented Soybean ◽  
Soybean Extract

scholarly journals Probiotic supplementation attenuates increases in body mass and fat mass during high-fat diet in healthy young adults

Obesity ◽  
2015 ◽  
Vol 23 (12) ◽  
pp. 2364-2370 ◽  
Author(s):  
Kristin L. Osterberg ◽  
Nabil E. Boutagy ◽  
Ryan P. McMillan ◽  
Joseph R. Stevens ◽  
Madlyn I. Frisard ◽  
...  
Keyword(s):  
Young Adults ◽  
Body Mass ◽  
Fat Mass ◽  
High Fat Diet ◽  
High Fat ◽  
Probiotic Supplementation

scholarly journals Effects of High-Fat Diet and Body Mass on Bone Morphology and Mechanical Properties in 1100 Advanced Intercross Mice

2019 ◽  
Vol 34 (4) ◽  
pp. 711-725 ◽  
Author(s):  
Matthew J Silva ◽  
Jeremy D Eekhoff ◽  
Tarpit Patel ◽  
Jane P Kenney-Hunt ◽  
Michael D Brodt ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Body Mass ◽  
High Fat Diet ◽  
Bone Morphology ◽  
High Fat ◽  
Morphology And Mechanical Properties

scholarly journals Assessment of the Hypoglycemic Effects of the Aqueous Extracts of Bauhinia forficata in Wistar Rats Fed with a High Fat Diet

2018 ◽  
Vol 10 (3) ◽  
pp. 62
Author(s):  
Igor F. S. Oliveira ◽  
Hellen S. Neves ◽  
Myllena F. Franco ◽  
Aluana S. Carlos ◽  
Simoni M. Medeiros ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Food Intake ◽  
Body Mass ◽  
High Fat Diet ◽  
Experimental Period ◽  
High Fat ◽  
Mineral Salts ◽  
Bauhinia Forficata ◽  
Pharmacological Potential ◽  
Group D

This study aimed at analyzing both body and glycemic parameters resulting from the administration of high fat diet and Bauhinia forficata aqueous extract (AqE) in rats. Initially, sixty-day-old rats were divided into two groups. Group C was fed with normocaloric diet and group D was fed with a high fat diet composed of 20% proteins; 48% carbohydrate, 20% lipid, 4% cellulose, 5% vitamin and mineral salts. On the 120 day-old group D was subdivided with another D + I group, fed a hyperlipid diet plus administration of Bauhinia forficata AqE for gavage. During experimental period, body mass, food intake and glucose were evaluated. The animals were sacrificed at the age of 150 days. Group D, at 120 days, presented higher body mass compared to group C, but there were no changes in dietary intake. The glycaemia of group D increased compared to group C. At 150 days, the D + I group had a decrease in body mass and glycaemia, and group D continued to gain body mass without changing food intake. Therefore, the findings show that the two-month-diet-period increased body weight and blood glucose. AqE of plant B. forficata has pharmacological potential in reducing body mass and decreasing in blood glucose concentrations.

Bisphenol A Promotes Adiposity and Inflammation in a Nonmonotonic Dose-response Way in 5-week-old Male and Female C57BL/6J Mice Fed a Low-calorie Diet

Endocrinology ◽  
2016 ◽  
Vol 157 (6) ◽  
pp. 2333-2345 ◽  
Author(s):  
Minglan Yang ◽  
Maopei Chen ◽  
Jiqiu Wang ◽  
Min Xu ◽  
Jichao Sun ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Bisphenol A ◽  
Body Mass ◽  
Fat Mass ◽  
High Fat Diet ◽  
Inflammatory Factors ◽  
Chow Diet ◽  
High Fat ◽  
Male And Female

A growing body of epidemiological research show that Bisphenol A (BPA) is positively correlated with obesity and metabolic disorders. However, the mechanisms of BPA on adiposity remain largely unknown. In this study, we found that 5-week-old male and female C57BL/6J mice exposed to four dosages of BPA (5, 50, 500, and 5000 μg/kg/d) by oral intake for 30 days showed significantly increased body weight and fat mass in a nonmonotonic dose-dependent manner when fed a chow diet. The effect occurred even at the lowest concentration (5μg/kg/d), lower than the tolerable daily intake of 50 μg/kg/day for BPA. However, no significant difference in body weight and fat mass was observed in either male or female mice fed a high-fat diet, suggesting that BPA may interact with diet in promoting obesity risk. In vitro study showed that BPA treatment drives the differentiation of white adipocyte progenitors from the stromal vascular fraction, partially through glucocorticoid receptor. BPA exposure increased circulating inflammatory factors and the local inflammation in white adipose tissues in both genders fed a chow diet, but not under high-fat diet. We further found that BPA concentration was associated with increased circulating inflammatory factors, including leptin and TNFα, in lean female subjects (body mass index < 23.0 kg/m2) but not in lean male subjects or in both sexes of overweight/obese subjects (body mass index > 25.0 kg/m2). In conclusion, we demonstrated the nonmonotonic dose effects of BPA on adiposity and chronic inflammation in 5-week-old mice, which is related to caloric uptake.

scholarly journals A High-Fat Diet Elicits Differential Responses in Genes Coordinating Oxidative Metabolism in Skeletal Muscle of Lean and Obese Individuals

2011 ◽  
Vol 96 (3) ◽  
pp. 775-781 ◽  
Author(s):  
K. E. Boyle ◽  
J. P. Canham ◽  
L. A. Consitt ◽  
D. Zheng ◽  
T. R. Koves ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Body Mass Index ◽  
Lipid Oxidation ◽  
Body Mass ◽  
High Fat Diet ◽  
High Fat ◽  
Insulin Resistant ◽  
Before And After ◽  
Mrna Content ◽  
Obese Subjects

Context: In lean individuals, increasing dietary lipid can elicit an increase in whole body lipid oxidation; however, with obesity the capacity to respond to changes in substrate availability appears to be compromised. Objective: To determine whether the responses of genes regulating lipid oxidation in skeletal muscle differed between lean and insulin resistant obese humans upon exposure to a high-fat diet (HFD). Design and Setting: A 5-d prospective study conducted in the research unit of an academic center. Participants: Healthy, lean (n = 12; body mass index = 22.1 ± 0.6 kg/m2), and obese (n=10; body mass index = 39.6 ± 1.7 kg/m2) males and females, between ages 18 and 30. Intervention: Participants were studied before and after a 5-d HFD (65% fat). Main Outcome Measures: Skeletal muscle biopsies (vastus lateralis) were obtained in the fasted and fed states before and after the HFD and mRNA content for genes involved with lipid oxidation determined. Skeletal muscle acylcarnitine content was determined in the fed states before and after the HFD. Results: Peroxisome proliferator activated receptor (PPAR) α mRNA content increased in lean, but not obese, subjects after a single high-fat meal. From Pre- to Post-HFD, mRNA content exhibited a body size × HFD interaction, where the lean individuals increased while the obese individuals decreased mRNA content for pyruvate dehydrogenase kinase 4, uncoupling protein 3, PPARα, and PPARγ coactivator-1α (P ≤ 0.05). In the obese subjects medium-chain acylcarnitine species tended to accumulate, whereas no change or a reduction was evident in the lean individuals. Conclusions: These findings indicate a differential response to a lipid stimulus in the skeletal muscle of lean and insulin resistant obese humans.

Adaptive characters of energy metabolism, thermogenesis and body mass in Eothenomys miletus during cold exposure and rewarming

2012 ◽  
Vol 62 (3) ◽  
pp. 263-276 ◽  
Author(s):  
Zhu Wan-long ◽  
Cai Jin-hong ◽  
Lian Xiao ◽  
Wang Zheng-kun
Keyword(s):  
Ambient Temperature ◽  
Energy Intake ◽  
Body Mass ◽  
Uncoupling Protein ◽  
Resting Metabolic Rate ◽  
Serum Leptin ◽  
Body Mass Regulation ◽  
Brown Adipose ◽  
And Behavior ◽  
Eothenomys Miletus

Environmental cues play important roles in the regulation of an animal’s physiology and behavior. The purpose of the present study was to test the hypothesis that ambient temperature was a cue to induce adjustments in body mass, energy intake and thermogenic capacity, associated with changes in serum leptin levels inEothenomys miletus. We found thatE. miletusincreased resting metabolic rate (RMR) and energy intake and decreased body mass when exposed to cold while it showed a significant increase in body mass after rewarming. The increase in body mass after rewarming was associated with the higher energy intake compared with the control. Uncoupling protein 1 (UCP1) content in brown adipose tissue (BAT) increased in the cold and reversed after rewarming. Serum leptin levels decreased in the cold while increased after rewarming, associated with the opposite changes in energy intake. Further, serum leptin levels were positively correlated with body mass and body fat mass. Together, these data supported our hypothesis that ambient temperature was a cue to induce changes in body mass and metabolism. Serum leptin, as a starvation signal in the cold and satiety signal in rewarming, was involved in the processes of thermogenesis and body mass regulation inE. miletus.

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