scholarly journals Peculiarities of blood flow in uterus and ovarius in the presence of diffusive form adenomyosis

2004 ◽  
Vol 53 (4) ◽  
pp. 33-37
Author(s):  
I. A. Semenov ◽  
N. G. Pavlova ◽  
D. А. Niauri ◽  
L. K. Dzhemlikhanova
Keyword(s):  
Blood Flow ◽  
Luteinizing Hormone ◽  
Regional Blood Flow ◽  
Follicle Stimulating Hormone ◽  
Control Group ◽  
Stimulating Hormone

The exploration of parameters of regional blood flow in aa. uterinae in 22 patients with diffusive form of adenomyosis, in which ovulational menstruational cycle with the lack of lutein phase was registrated and 10 women of control group in dynamics of menstruational cycle. The levels of follicle stimulating hormone, luteinizing hormone, prolactine, estradiole and progesterone were examined in patients blood. The results showed, that adenomyosis is followed by normogonadotropic normoprolactinaemic insufficiency of ovaries, with the increased aa. uterinae vessel resistence background.

scholarly journals Effects of l-Carnitine on the Follicle-Stimulating Hormone, Luteinizing Hormone, Testosterone, and Testicular Tissue Oxidative Stress Levels in Streptozotocin-Induced Diabetic Rats

2018 ◽  
Vol 23 ◽  
pp. 2515690X1879605 ◽  
Author(s):  
Nourollah Rezaei ◽  
Tahereh Mardanshahi ◽  
Majid Malekzadeh Shafaroudi ◽  
Saeed Abedian ◽  
Hamid Mohammadi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Serum Levels ◽  
Diabetic Rats ◽  
Diabetic Group ◽  
Control Group ◽  
Group Vi ◽  
Group I ◽  
Stimulating Hormone

The present study was designed to investigate the antioxidant property of l-carnitine (LC) on serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone (TH) and testis oxidative stress in streptozotocin (STZ)-induced diabetic rats. The rats were divided into the following groups: group I, control; group II, LC 100 mg/kg/d; group III, diabetic; and groups IV to VI, diabetic rats treated with 50, 100, and 200 mg/kg/d of LC, respectively. Daily injections were given intraperitoneally for 7 weeks. At the end of experimental period, after sacrificing the rats, FSH, LH, TH, total antioxidant capacity (TAC), malondialdehyde (MDA), glutathione (GSH), catalase (CAT), mitochondrial function (MTT), protein carbonyl (PC), and reactive oxygen species (ROS) levels were measured. STZ caused an elevation of MDA, ROS, and PC ( P < .001) with reduction of GSH, CAT, TAC, and MTT ( P < .001) in the serum levels. Group VI had significantly increased FSH, LH, and TH levels versus the untreated diabetic group ( P < .001). Although groups V and VI significantly decreased MDA ( P < .001), PC ( P < .01), and ROS ( P < .01) compared with the untreated diabetic group; only in group VI, the activity of GSH ( P < .001), CAT ( P < .01), TAC ( P < .001), and MTT ( P < .001) significantly increased. The results of the present study suggest that LC decreased diabetes-induced oxidative stress complications and also improved serum level of FSH, LH, and TH by reducing levels of lipid peroxidation and increasing antioxidant enzymes.

Features of the functional state of the pituitary-ovarian systems in women with polycystic ovary syndrome at different periods of reproductive age

2020 ◽  
Vol 75 (6) ◽  
pp. 653-660
Author(s):  
O. V. Krusko ◽  
L. F. Sholokhov ◽  
L. V. Belenkaya ◽  
M. A. Rashidova ◽  
I. N. Danusevich ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Follicle Stimulating Hormone ◽  
Reproductive Age ◽  
Sex Steroid ◽  
Control Group ◽  
Ovary Syndrome ◽  
Steroid Binding ◽  
Stimulating Hormone

Background. PCOS is one of the most common endocrinological pathologies in women of reproductive age, manifested by a wide range of clinical manifestations. There are many unresolved issues related to the pathogenesis, diagnosis and treatment of this pathological condition in different periods of reproductive age. Aim the objective of the study was to identify the features of the functioning of the pituitary-ovarian system in women with PCOS at different periods of reproductive age. Methods. Study was performed in 20172019 at the FSPSI SCFHHRP, and involved women aged 1845 years. The study groups included women (a group of women with PCOS and a control group) in the follicular phase from 1 to 12 days of the menstrual cycle. As a result of the survey, a group of 44 women with PCOS and a group of 56 healthy women were formed. PCOS was diagnosed according to ESHRE/ASRM criteria (Rotterdam, 2003). Next, subgroups of women in early reproductive age from 35 to 45 years were formed: a group of women with PCOS (n = 29) and a control group (n = 22). And groups of women in late reproductive age from 35 to 45 years were formed: a group of women with PCOS (n = 15) and a control group (n = 34). Conducted: questionnaire survey, general and gynecological examination, ultrasound examination of the pelvic organs, laboratory tests, statistical data analysis. Results. In women with polycystic ovary syndrome of early reproductive age (1835 years), we detected an increase in the level of testosterone by 2 times, DHEA-S by 1.3 times, 17-OH-progesterone by 2 times, sex steroid-binding globulin by 1.4 times, in comparison with control group. The ratio of luteinizing hormone to follicle-stimulating hormone increased by 52%. In women with polycystic ovary syndrome of late reproductive age (3545 years), we detected an increase in the level of testosterone by 1.5 times, 17-OH-progesterone by 1.9 times, luteinizing hormone by 1.4 times, sex steroid-binding globulin by 1.6 times, in comparison with control group, without any significant differences in DHEA-S. At the same time, the ratio of luteinizing hormone to follicle-stimulating hormone increased by 60%. Conclusion. The hormonal profile of women with PCOS of early and late reproductive period is characterized by series of age-related changes in the pituitary-ovarian system, which should be taken into account in preventive and therapeutic measures.

scholarly journals Comparative Modulation of the Reproductive System by Ethanolleaf Extracts of Asystasia Gangetica Andanthocleista Vogelli in Male Wistar Rats

2020 ◽  
Vol 2 (3) ◽  
Author(s):  
Simeon I. Egba ◽  
C. O. Okonkwo ◽  
H. C. Omeoga ◽  
I. E. Ekong
Keyword(s):  
Luteinizing Hormone ◽  
Reproductive System ◽  
Wistar Rats ◽  
Follicle Stimulating Hormone ◽  
Reproductive Hormones ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Albino Rats ◽  
Male Wistar Rats ◽  
Stimulating Hormone

A number of medicinal plants have been found to influence the level of reproductive hormones and thus affect fertility in the overall. This work evaluated the effects of ethanol leaf extracts of A. gangetica and A. vogelli respectively on some reproductive system parameters in male Wistar rats. A total of sixteen (16) male albino rats were grouped into four (four rats in each group): group A served as normal control, group B received Immunace (Vitabiotics) group C and D received 400 mg/kg body weight of A. gangetica and A. vogelli extracts respectively. Extracts were administered orally to rats for 21 days, after which they were sacrificed by cervical dislocations and blood samples drawn by cardiac puncture. The effect of the extracts on testosterone, follicle stimulating hormone, luteinizing hormone and semen analysis of the test rats were determined using enzyme linked immunosorbent assay (ELISA) and standard techniques. Data collected were analyzed using Graph pad prism V6 and p values < 0.05 were adopted as significant. There was no significant (p>0.05) change in testosterone, FSH and luteinizing hormones in the group administered A. gangetica plant extract relative to the control. There was also no visible difference in the testes weight and sperm morphology relative to the control group. In contrast, administration of A. vogelli extract caused significant (p<0.05) decrease in testosterone and follicle stimulating hormone concentrations from: 1.12 ± 0.20 to 0.89 ± 0.05 and 1.41 ± 0.07 to 1.35 ± 0.12 respectively relative to the control group. While significant (p<0.05) decrease in luteinizing hormone (1.71 ± 0.15) was observed relative to the standard drug group (1.76 ± 0.05). A significant (p<0.05) decrease in sperm count and testes weight was also observed in rats treated with A. vogelli extract relative to the normal control.The results suggest that, A. vogelli extract may cause decreased fertility in male albino rats and could be developed further into potent male contraceptives. A. gangetica on the other hand, had no effect on male reproductive hormones.

scholarly journals Effect of 3 Months Exercise on Ovarian Reserve and Ovulatory Status of Premenopausal Students of Nnamdi Azikiwe University, Nnewi Campus

2022 ◽  
Vol 12 (1) ◽  
pp. 78-86
Author(s):  
Njoku CM ◽  
Meludu SC ◽  
Dioka CE
Keyword(s):  
Luteinizing Hormone ◽  
Ovarian Reserve ◽  
Follicle Stimulating Hormone ◽  
Premenopausal Women ◽  
Exercise Group ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Vigorous Exercise ◽  
Vigorous Intensity ◽  
Stimulating Hormone

There is a traditional believe that if premenopausal women engage in prolonged physical exercise, they are likely to have infertility. This study assessed the effect of prolonged moderate – vigorous exercise on ovarian reserve and ovulatory status in premenopausal students of Nnamdi Azikiwe University, Nnewi Campus. The objectives were to determine the effect of moderate – vigorous intensity exercise on Anti-Mullerian hormone (AMH), day 3 Follicle stimulating hormone (FSH), Luteinizing Hormone (LH), day 3 Estrogen, day 21 Estrogen, and day 21 Progesterone levels in premenopausal women. This was a prospective comparative study involving 80 participants aged between 19 and 25 years, randomly selected and assigned to exercise group and control group. The exercise group comprised 40 participants who engaged in moderate – vigorous intensity exercise using elliptical bike for 30 minutes, five days a week for 3 months; however, 30 individuals completed the exercise. The control group comprised of 40 individuals that did not do exercise but 30 individuals completed the study. Blood (8ml) was collected from each of the participants at baseline, 1 month, 2 months, and 3 months. AMH, FSH, LH, Estrogen and Progesterone levels were analyzed using enzyme- linked Immunosorbent assay (ELISA) method. Results were regarded as significant at p˂ 0.05. In the exercise group, the serum level of day 3 FSH, LH, Estrogen were significantly lower from 7.27±0.77 mIU/ml, 7.00±0.77 mIU/ml, 36.33±5.13 pg/ml respectively at baseline to 5.62±0.48 mIU/ml, 5.36±0.80 mIU/ml, 21.36±4.34 pg/ml respectively after 3 months of exercise while there was significantly higher levels of AMH and day 21 progesterone after 3 months of exercise compared with the baseline and respective control (p<0.05). Prolonged Moderate-to-vigorous exercise may enhance fertility and well-being of premenopausal women. Key words: Anti-Mullerian hormone (AMH), day 3 Follicle stimulating hormone (FSH), Luteinizing Hormone (LH), day 3 Estrogen, day 21 Estrogen, day 21 Progesterone, moderate – vigorous exercise, ovarian reserve, ovulatory status, premenopausal women.

Evaluation of carvacrol on pituitary and sexual hormones and their receptors in the testicle of male diabetic rats

2020 ◽  
Vol 39 (8) ◽  
pp. 1019-1030 ◽  
Author(s):  
H Shoorei ◽  
A Khaki ◽  
M Shokoohi ◽  
AA Khaki ◽  
A Alihemmati ◽  
...  
Keyword(s):  
Luteinizing Hormone ◽  
Protein Expression ◽  
Germ Cells ◽  
Sertoli Cells ◽  
Messenger Rna ◽  
Follicle Stimulating Hormone ◽  
Diabetic Group ◽  
Control Group ◽  
Mrna And Protein Expression ◽  
Stimulating Hormone

Diabetes mellitus (DM) is a complex metabolic disease and it is also closely associated with a reduction in fertility in male patients. The purpose of the present study was to investigate the antidiabetic effect of carvacrol (CRV), as a potent antioxidant, on the numbers of germ cells and Sertoli cells in testicular tissue, and the messenger RNA (mRNA) and protein expression of some genes involved in spermatogenesis, including luteinizing hormone/choriogonadotropin receptor ( LHCGR), follicle-stimulating hormone receptor ( FSHR), and steroidogenic factor 1 ( SF-1), as well as hormones such as luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone (T), and insulin. Adult male Wistar rats ( n = 32) were randomly divided into four groups (eight animals per group), including healthy control that received 0.2% Tween 80, diabetic control group, the diabetic group treated orally with CRV (75 mg/kg), and CRV group that received orally CRV (75 mg/kg). The duration of the treatment period lasted 8 weeks. In the diabetic group, the numbers of Sertoli cells and germ cells were significantly decreased, while the treatment with CRV prevented the degree of the damage to the cells mentioned earlier. CRV administration elevated the concentrations of insulin, T, FSH, and LH. Moreover, treatment with CRV significantly enhanced the levels of the mRNA and protein expression of SF-1, LHCGR, and FSHR. According to the obtained results, CRV administration could prevent the deleterious effects of DM on testicular germ cells, and it increases the levels of hormones and some essential genes, such as SF-1, LHCGR, and FSHR, involved in the process of spermatogenesis.

Influence of nutrition on pre-partum plasma levels of progesterone and total oestrogens and post-partum plasma levels of luteinizing hormone and follicle stimulating hormone in suckling cows

1983 ◽  
Vol 37 (1) ◽  
pp. 89-96 ◽  
Author(s):  
D. Gauthier ◽  
M. Terqui ◽  
P. Mauleon
Keyword(s):  
Luteinizing Hormone ◽  
Plasma Levels ◽  
Post Partum ◽  
Control Diet ◽  
Follicle Stimulating Hormone ◽  
Control Group ◽  
Luteinizing Hormone Concentration ◽  
The Mean ◽  
Daily Gain ◽  
Stimulating Hormone

ABSTRACTTwo groups of suckling Charolais cows were fed at different levels of nutrition from 70 days before the estimated date of calving until 45 days after calving, to study the effects of reduced dietary intake on pre-partum plasma levels of progesterone and total oestrogens (conjugated + unconjugated) and post-partum plasma levels of luteinizing hormone and follicle stimulating hormone. Eight control cows received a ration containing the Institut National de la Recherche Agronomique's recommendations for all nutrients, while 10 cows received a restricted diet which supplied approximately three-quarters of the recommended amounts for energy and nitrogen.The mean weight of the two groups of cows was similar at the beginning of the experiment but the restricted group had a significantly lower weight just before calving than the control group (678 v. 766 kg; P < 0·05).After calving, cows ont he low diet had a weight loss of 600 g/day, while those on the control diet gained 300 g/day. During the last 45 days of pregnancy underfeeding did not significantly affect oestrogen levels, but progesterone levels increased proportionally by 0·24 (P < 0·01).During the first 45 days of lactation underfeeding decreased the number of cows showing oestrus (0/10 v. 4/8) and significantly decreased both luteinizing hormone and follicle stimulating hormone levels at 5, 15 and 30 days post partum.Furthermore, the correlation between mean daily gain (0 to 45 days post partum) and luteinizing hormone concentration on day 30 was highly significant (r = 0·58; P < 0·01; no. = 19). These results suggest that the delay of the first post-partum ovulation in the underfed cow is due to low gonadotropin levels.

scholarly journals Short-term effect of Tramadol injection on the serum levels of Follicle Stimulating Hormone, Luteinizing Hormone and Testosterone in Male Sahel Goats in Maiduguri, Nigeria

2019 ◽  
Vol 7 (1) ◽  
pp. 6
Author(s):  
Babagana Bako ◽  
Sani Malami ◽  
Garba Uthman Sadiq ◽  
Lawan Gana Ashiekh
Keyword(s):  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Serum Levels ◽  
Term Effect ◽  
Control Group ◽  
High Dose ◽  
Short Term ◽  
Short Term Effect ◽  
Group 4 ◽  
Stimulating Hormone

Tramadol is a synthetic analogue of codeine. Its mood elevation property and sex enhancement potentials are the main reason for its abuse. The aim of the study was to determine the short-term effect of tramadol administration on Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH) and Testosterone (TEST) levels in Male Sahel Goats. This was an experimental study conducted from 1st October 2017 to 12th November 2017 at the Livestock Teaching and Research Farm, University of Maiduguri, Maiduguri, Borno State Nigeria involving 20 Male Sahel Goats. The goats were divided in to 4 groups of 5 each; group 1 served as control and groups 2, 3 and 4 were injected intramuscularly with 4 mg/kg (low dose), 8 mg/kg (medium dose) and 12 mg/kg (high dose) of Tramadol respectively. The injections were given intramuscularly, 3 times a week for 4 weeks. Blood samples were collected to determine the serum levels of FSH, LH and TEST at 0, 1 week, 2 weeks, 3 weeks and 4 weeks of tramadol injections. The Mean±SD of the hormones were computed using SPSS 20. The difference in mean was compared using t test and ANOVA with p < 0.05 set for statistical significance. The baseline levels of FSH, LH and TEST in Male Sahel Goat in Maiduguri were 2.91±5.74 Miu/ml, 0.29±0.72 Miu/ml and 3.92±6.39 ng/ml respectively. Only the goats in group 4 showed a significant increase in serum FSH and LH by the 4th week (P=0.01 and 0.03 respectively) while no significant change was noted in the other groups. The was a decline in the level of Testosterone from 1st week through 4th week in all the experimental group but the level in the control group remain fairly constant throughout the experiment. The decline is inversely proportional to the dose of tramadol injection and most marked in group 4.High dose and prolonged used of Tramadol should be avoided because of side effects of Hypergonadotrophic hypogonadism.  

Study the effect of alcoholic extractrawsalvia officnalis on some sex hormonesin female mice white

2018 ◽  
Vol 9 (SPL1) ◽  
Author(s):  
Frah razzaq Kbyeh
Keyword(s):  
Body Weight ◽  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Physiological Solution ◽  
Control Group ◽  
Alcoholic Extract ◽  
Female Mice ◽  
Group B ◽  
The Impact ◽  
Stimulating Hormone

 Thirty female mice white used in the experiment for the purpose of knowing the effect of alcoholic extract raw salvia officnalisleaves on the level of sex hormones which were divided animals into three groups experimental rate of ten mice per group dosage group B and C oral daily dose of the extract amount 500 mg / kg of body weight the first group, respectively,in the1000 mg/ Kg of body weight,respectively,either the first set group A treated the same way time and himself as 0.1 ml / g body weight of physiological solution compared to the mind set lasted 30 days dosing was weight when you stop recording the dosage and then kill her blood was collected through a stab heart for the purpose of studies of hormonal (estrogen,progesterone,luteinizing hormone,follicle stimulating hormone and prolactin)extract reflected the impact of the variables studied and related to fertility in the following results compared with the control group. Low body weight was in the doses and the effect of the dose of 1000 mg / kg of body weight was significantly larger dose of 500 mg / kg of body weight at a level significantly 5% P0≤0.05. Significant increase in the level of hormones (progesterone,estrogen,luteinizing hormone,follicle-stimulating hormone) in the doses and the effect of the dose of1000 mg / kg of body weight was significantly larger dose of 500 mg / kg of body weight at a level significantly 5% P0≤0.05. Significant decrease in the level of the hormone prolactin in the doses and the effect of the dose of 1000 mg / kg of body weight was significantly larger dose of 500 mg / kg of body weight at a level significantly 5% P0≤0.05

scholarly journals Significance of hyperprolactinemia for cytomorphologic features of breast secretions

2010 ◽  
Vol 67 (1) ◽  
pp. 42-47
Author(s):  
Danijela Radojkovic ◽  
Slobodan Antic ◽  
Milica Pesic ◽  
Milan Radojkovic ◽  
Dijana Basic ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Luteinizing Hormone ◽  
Follicle Stimulating Hormone ◽  
Nipple Discharge ◽  
Thyroid Stimulating Hormone ◽  
Serum Prolactin ◽  
Control Group ◽  
Clinical Group ◽  
Group I ◽  
Stimulating Hormone

Background/Aim. Nipple discharge syndrome is a clinical entity capable of presenting various disorders such is mammary infection (nonpuerperal and puerperal mastitis), intraductal papillomas, fibrodenoma, breast cancer and hyperprolactinemia syndrome. The aim of the study was to determine differencies in cytological features of mammary secretion in patients with hyperprolactinemia and those with normal serum prolactin levels and to define the role of growth hormone, follicle-stimulating hormone, luteinizing hormone and thyroid-stimulating hormone in creating cellular profile of breast secretion. Methods. The study included 50 patients with nipple discharge syndrome. The patients were devided into the clinical group (27 patients with hyperprolactinemia and nipple discharge) and the control group I (23 patients with normal serum prolactin and nipple discharge). The control group II included the patients of the clinical group achiving normalised serum prolactin levels after the treatment of hyperprolactinemia. Serum prolactin, follicle-stimulating hormone and luteinizing hormone levels were assessed by RIA using commercial kits IRMA hPRL, hLH and hFSH, (INEP, Zemun, Serbia) while serum growth hormone and thyroid-stimulating hormone levels were assessed by RIA using commercial kits LKB-wallac. Cytologic evaluation of samples, taken from all the patients with mammary secretion, was done using standard techniques of staining Haemathoxilin-eozine and May- Gr?nwald/Giemsa. Results. Our results showed a significantly higher presence of lipid and protein material in clinical group, in comparison with the control group I (p < 0.01). Also, our data demonstrated significantly higher number of ductal epithelial cells (p < 0.05) and ductal histiocities (p < 0.001) in the clinical group, compared with the control group I. Macrophagies frequency was proportionally higher in clinical group (44.44%) compared the control group I (17.39%). Erythrocites were significantly lower in the clinical group (p < 0.001) than in the control group I. Significantly decreased mammary secretion (p < 0.01), lower lipid (p < 0.01) and protein synthesis (p < 0.01), and less presence of all cellular categories (p < 0.01) were obtained after normalization of serum prolactin levels. Conclusion. Growth hormone, follicle-stimulating hormone, luteinizing hormone and thyroid-stimulating hormone did not show significant influence on creating cytological features of mammary secretion. The most expressive role, hyperprolactinemia demonstrated in the domain of mammary ductal secretory activity, making mammary secretion reach in lipid and protein material and simultaneously increasing number of ductal epithelial cells, ductal histiocytes and 'foam cells'- macrophages. These cytological findings indicate that hyperprolactinemia promote periductal and intraductal steril inflammation which withdraws after serum prolactin normalization.

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