On the clinical significance of the study of the morphological composition of the cantharidin bladder in allergic conditions

1937 ◽  
Vol 33 (5) ◽  
pp. 554-561
Author(s):  
K. E. Myasnikov
Keyword(s):  
Clinical Significance ◽  
Experimental Work ◽  
Morphological Changes ◽  
Important Conclusion ◽  
Morphological Composition ◽  
Inflammatory Processes ◽  
Morphological Processes ◽  
To Come

Ressle's experimental work on the study of inflammatory processes in allergies and the connection of morphological changes with the phenomena of immunity gave him the opportunity to come to an important conclusion that "morphological processes in the foci of inflammation are one of the most subtle indicators of the onset of allergies, even the mildest degrees of it."

scholarly journals The State of the Hemomycocirculatory Bed of Adventitia of Varicose Veins of the Small Pelvis in Women with Chronic Inflammatory Diseases of the Internal Genital Organs

2017 ◽  
Vol 23 (2) ◽  
Author(s):  
Natalya Drohomyretska
Keyword(s):  
Inflammatory Diseases ◽  
Varicose Veins ◽  
Morphological Changes ◽  
Complex Structure ◽  
The State ◽  
Reproductive Age ◽  
Ovarian Vein ◽  
Women Of Reproductive Age ◽  
Vein Wall ◽  
Inflammatory Processes

Hemomicrocirculatory system – is a complex structure that reacts in every pathological process even before the clinical period and takes the first blow. The study of microhemocirculation will provide an opportunity to solve the important for practical medicine questions of pathogenesis of many diseases, as for the prevention and treatment of regional disorders of blood circulation.The objective of the research is to study the state of the hemomicrocirculatory bed (HMCB) of adventitia of varicose veins of the small pelvis (VVSP) in women with chronic inflammatory processes of the organs of the small pelvis (CIPOSP).Materials and methods of research. To evaluate the restructuring of the HMCB of adventitia of VVSP, the operating material of 12 women of reproductive age was used. Mainly, there were pieces of the ovarian vein. The study of the HMCB in the vein wall was performed by the non-injecting method of silver impregnation according to V.V. Kupriyanov. To standardize the results, the condition of the HMCB of adventitia of the venous wall in norm was studied in 5 women of reproductive age, who died as a result of various traumas.Results of the research. After the performed studies, the structural-morphological changes of the HMCB of the adventitia of the small pelvis veins were revealed. The dilation of capillaries, postcapillaries, postcapillary venules was observed. The diameter of the vessels of the HMCB of the ovarian vein adventitia was: venule – 94.21 ± 1.38 μM in comparison with the norm – 48.78 ± 1.60 μM (p<0.001); post-capillary venules – 46.76 ± 1.04 μM in comparison with the norm – 28.29 ± 1.1.01 μM (p<0.001); the capillaries were 11.22 ± 0.14 μM in comparison with the norm – 8.24 ± 0.16 μM (p<0.05), arterioles – 29.02 ± 0.76 μM in comparison with the norm – 25.19 ± 1.15 μM (p<0.01). The architectonics of the arterioles is almost unchanged. Lumen of venules is filled with formed elements. The structure of capillaries is polymorphic. The capillary net was localized and concentrated or was formed as a thick planar net, the capillaries were expanded. There were arterio-venulous anastomoses. Endothelial nuclei are shortened. In some preparations, the diameter of the arterioles corresponded to the diameter of the collection venules.  Conclusions:1. The first discovered by us changes in HMCB of adventitia of varicose veins of the small pelvis in women with CIPOSP can be one of the pathogenetic links of the development and progression of the varicose vein itself, which in turn aggravates the course of chronic inflammation.      2. The timely appointment of drugs that improve microcirculation will enable to prevent the development of dystrophic changes in the vein wall, improve the course of chronic inflammatory processes and reduce or completely eliminate the syndrome of “chronic pelvic pain”.

scholarly journals MORPHOLOGICAL CHARACTERISTICS OF PERIPHERAL BLOOD OF COWS INFECTED WITH BLV AND THE FREQUENCY OF REGISTRATION OF LEUKEMOID REACTIONS IN COWS WITH LEUKEMIA-AFFECTED HERDS

2020 ◽  
pp. 66-72
Author(s):  
P. N. Smirnov ◽  
S. M. Chudum ◽  
I. V. Trostyansky ◽  
O. S. Kotlyarova
Keyword(s):  
Successful Treatment ◽  
Peripheral Blood ◽  
Serum Proteins ◽  
Morphological Characteristics ◽  
Controlled Experiments ◽  
Individual Analysis ◽  
Morphological Composition ◽  
Inflammatory Processes

In controlled experiments during planned studies of cattle for leukemia, animals that showed leukemoid changes in blood – quantitative redistribution of granulocytes and agranulocytes-were identified. Individual analysis revealed that granulocytosis was detected in animals with inflammatory processes. In addition, the article presents comparative indicators of serum proteins in cows at the hematological stage of the leukemic process, with the manifestation of leukemoid reactions and in clinically healthy cows. Characteristic changes in the synthesis of immunoglobulins in cows with leukemia and leukemoid changes in the morphological composition of blood were established. With successful treatment of inflammatory processes, the hematological status of cows is restored to the initial indicators.

The protease-activated receptor-2 upregulates keratinocyte phagocytosis

2000 ◽  
Vol 113 (17) ◽  
pp. 3093-3101 ◽  
Author(s):  
E.R. Sharlow ◽  
C.S. Paine ◽  
L. Babiarz ◽  
M. Eisinger ◽  
S. Shapiro ◽  
...  
Keyword(s):  
Serine Proteases ◽  
Actin Polymerization ◽  
Transmembrane Domain ◽  
Morphological Changes ◽  
Human Keratinocytes ◽  
E Coli ◽  
Inflammatory Processes ◽  
Tethered Ligand ◽  
K 12 ◽  
Protease Activated Receptor 2

The protease-activated receptor-2 (PAR-2) belongs to the family of seven transmembrane domain receptors, which are activated by the specific enzymatic cleavage of their extracellular amino termini. Synthetic peptides corresponding to the tethered ligand domain (SLIGRL in mouse, SLIGKV in human) can activate PAR-2 without the need for receptor cleavage. PAR-2 activation is involved in cell growth, differentiation and inflammatory processes, and was shown to affect melanin and melanosome ingestion by human keratinocytes. Data presented here suggest that PAR-2 activation may regulate human keratinocyte phagocytosis. PAR-2 activation by trypsin, SLIGRL or SLIGKV increased the ability of keratinocytes to ingest fluorescently labeled microspheres or E. coli K-12 bioparticles. This PAR-2 mediated increase in keratinocyte phagocytic capability correlated with an increase in actin polymerization and *-actinin reorganization, cell surface morphological changes and increased soluble protease activity. Moreover, addition of serine protease inhibitors downmodulated both the constitutive and the PAR-2 mediated increases in phagocytosis, suggesting that serine proteases mediate this functional activity in keratinocytes. PAR-2 involvement in keratinocyte phagocytosis is a novel function for this receptor.

scholarly journals Morphological Changes of Placenta in Preeclampsia

1970 ◽  
Vol 7 (1) ◽  
pp. 49-54 ◽  
Author(s):  
Segupta Kishwara ◽  
Shamim Ara ◽  
Khandaker Abu Rayhan ◽  
Mahamuda Begum
Keyword(s):  
Morphological Changes ◽  
Medical College ◽  
Group A ◽  
Different Shapes ◽  
The Difference ◽  
To Come ◽  
Group B ◽  
Larger Sample ◽  
Normal Placenta ◽  
Human Placentae

Context: Preeclampsia is regarded as a risk factor in pregnancy and it leads to placental insufficiency. This, in turn causes both maternal and fetal morbidity and mortality. The present study intends to compare the morphological changes of placenta in preeclampsia with that of normal placenta. Study design: A descriptive type of study. Place and period of study: Department of Anatomy, Dhaka Medical College, Dhaka, from August 2005 to June 2006. Materials: 60 human placentae, 30 were from normal pregnant women as control and 30 from pregnancies complicated by preeclampsia were taken for this study. Method: Samples were grouped as Group A and Group B on the basis of presence or absence of preeclampsia. All samples were studied morphologically. Result: Different shapes of placenta were found with some having accessory lobes in both groups. There was significant reduction (p< 0.001) in diameter and volume of placenta in Group B. The thickness of placenta was reduced in Group B but the difference did not reach a significant level. The number of cotyledon was significantly reduced in Group B (p<0.05). Conclusion: In this study, it was found that the preeclamptic placentae underwent definite morphological changes. These changes seemed to be the result of insufficiency of placenta in preeclampsia. However, further histological and morphometric placental study in a larger sample has to be conducted to come up with a conclusive decision. Key Words: Placenta, Preeclampsia, Morphology.   doi: 10.3329/bja.v7i1.3026 Bangladesh Journal of Anatomy January 2009, Vol. 7 No. 1 pp. 49-54

Fading Memory Formulation for Active Stress Fibre Contractility

2010 ◽  
Author(s):  
Patrick McGarry ◽  
Robert M. McMeeking ◽  
Vikram S. Deshpande
Keyword(s):  
Experimental Work ◽  
Contractile Response ◽  
Morphological Changes ◽  
Cytochalasin D ◽  
In Vitro Studies ◽  
Fading Memory ◽  
Active Stress ◽  
Cyclic Stretching ◽  
Stress Fibre

Cytoskeletal alignment and morphological changes in cells under conditions of cyclic stretching have been reported in several in-vitro studies. Of particular interest is the experimental work of Wille et al. [1] in which the contractile response of fibroblast stress fibres was isolated and quantified by testing both untreated cells and cells treated with Cytochalasin-D.

scholarly journals Avaliação macro e microscópica do trato digestório de frangos de corte alimentados com dieta contendo glicerina

2017 ◽  
Vol 8 (1) ◽  
pp. 59 ◽  
Author(s):  
Denise Cerqueira Sousa ◽  
Nadja Lamonye Alves Oliveira ◽  
Edna Teles dos Santos ◽  
Leilane Rocha Barros Dourado ◽  
Guilherme José Bolzani de Campos Ferreira
Keyword(s):  
Inflammatory Process ◽  
Morphological Changes ◽  
Lymphatic Tissue ◽  
Randomized Design ◽  
Significant Difference ◽  
Inflammatory Processes ◽  
Passive Absorption ◽  
Completely Randomized Design ◽  
Mucus Barrier ◽  
Inflammatory Infiltrates

This study aimed to evaluate the presence of morphological changes in the digestive tract of broilers fed diets containing 7% glycerol. It was used 16 animals from male Cobb 500® line, distributed in a completely randomized design in two treatments: animals fed diet without glycerin and animals fed diets containing 7% glycerol. It was observed that the addition of glycerin at 7% in the diet of broilers promotes the occurrence of significant inflammatory infiltrates in the proventriculus, caecum and colon of such animals, macroscopically the addition of glycerin in the diet did not cause any significant difference, but these differences had no significant effect on zootechnical development of such animals. It is possible to conclude that the use of glycerin in the diet can cause localized inflammatory processes, due to its alcoholic feature that degrades the protective mucus barrier and it presents passive absorption and exposes the mucus epithelium to the gastric juice action, thus promoting the mucosa inflammatory process. In the large intestine (cecum and colon) the inflammatory response showed greater intensity as a function of these organs have higher lymphatic tissue (nodular and diffuse)concentration and at this portion the intestine performs the fluids reabsorption directly competing with glycerin which is highly hygroscopic.

scholarly journals Clinical and haematological indices of the cows for acute catarrhal-purulent endometritis

2018 ◽  
Vol 20 (92) ◽  
pp. 121-124
Author(s):  
L. V. Koreyba
Keyword(s):  
Phagocytic Activity ◽  
Clinical Signs ◽  
Dairy Herd ◽  
The Body ◽  
Natural Resistance ◽  
Spring Period ◽  
Morphological Composition ◽  
Inflammatory Processes ◽  
Haemoglobin Content ◽  
Haematological Indices

Postpartum inflammatory processes in the genital organs are enough common reason of prolonged symptomatic infertility, which is from 10 to 72% of the total dairy herd of cows and are often registered in the form acute endometritis. The goal of the work was to study non-specific indicators resistance in healthy and illness with catarrhal purulent endometritis of cows. The haematological tests research were carried out during the winter-spring period on cows of four groups, which were formed on the basis of analogues and on the basis of clinical and gynaecological investigations. Presented data regarding special feature of clinical signs of postnatal endometritis in cows. In cows during the puerperal period recorded acute serous of endometritis purulent-catarrhal. The acute catarrhal purulent endometritis causes in cows significant changes in the morphological composition of blood and all investigated units of natural resistance. In illness  cows with compared to healthy ones pregnant cows have had an undoubted increase in haemoglobin content (by 15.4%), the number of eosinophils and  neutrophils which core has rod shape; an increase in the number of leukocytes (by 8.3%) and a decrease in lymphocytes, bactericidal (10.42%) and lysozyme activity of plasma (0.96%) was not reliable. The low index of phagocytic activity for acute postpartum endometritis suggests the inhibition of phagocytosis in the body of illness cows. The acute catarrhal purulent endometritis causes in cows significant changes in the morphological composition of blood and all investigated units natural resistance. The low index of phagocytic activity for such state as acute postpartum endometritis suggests the inhibition of phagocytosis in the body of illness cows. Further work will be focused on the using of indices of non-specific resistance of cows for prediction and correction of inflammatory processes in the uterus.

scholarly journals A SYSTEM OF MATHEMATICAL MODELS FOR THE SIMULATION OF MORPHOLOGICAL PROCESSES IN THE COASTAL AREA

1984 ◽  
Vol 1 (19) ◽  
pp. 98 ◽  
Author(s):  
S. Boer ◽  
H.J. De Vriend ◽  
H.G. Wind
Keyword(s):  
Mathematical Model ◽  
Mathematical Models ◽  
Coastal Area ◽  
Morphological Changes ◽  
Coastal Engineering ◽  
Coastal Processes ◽  
Morphological Processes ◽  
The Individual ◽  
Near Future

A compound mathematical model (COMOR) for the simulation of morphological changes in the coastal area is being developed. The model is very flexible; it can be composed according to the specific demands of the problem which is considered. So far the model is being applied in the advisory practice to predict initial morphological changes. Recent experiences have shown that the model is quite useful, although at present the knowledge of the individual coastal processes and their interactions is still insufficient to utilize it optimally. However, it is foreseen that in the near future such mathematical models will become a powerful tool in coastal engineering.

Modeling the Active Contractility of Cells Under Dynamic Loading

2009 ◽  
Author(s):  
Patrick McGarry ◽  
Anthony G. Evans ◽  
Robert M. McMeeking ◽  
Vikram S. Deshpande
Keyword(s):  
Dynamic Loading ◽  
Experimental Work ◽  
Contractile Response ◽  
Morphological Changes ◽  
Cytochalasin D ◽  
In Vitro Studies ◽  
Cyclic Stretching ◽  
In Cells

Cytoskeletal alignment and morphological changes in cells under conditions of cyclic stretching have been reported in several in-vitro studies. Of particular interest is the experimental work of Wille et al. [1] in which the contractile response of fibroblasts was isolated and quantified by testing both untreated cells and cells treated with Cytochalasin-D.

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