Assessment of the therapeutic efficacy of various drugs against cryptosporidiosis in calves

The purpose of the research is studying the spread of cryptosporidiosis in calves and assessment of the extenseeffectiveness of antiprotozoal drugs.Materials and methods. The spread, seasonal and age-specific trends of cryptosporidiosis was studied on 395 spontaneously infected animals of five age groups. The first group was formed of calves up to 10 days of age, the second group of calves aged from 11 days to 2 months, the third group of calves from 2 to 4 months, the fourth group of calves from 4 to 6 months of age, and the fifth group of young animals from 6 months up to 1 year. To assess the efficacy of various drugs against cryptosporidiosis in calves, 5 groups of infected animals (4 experimental and 1 control), 10 animals each, were formed according to the principle of analogous pairs. The infection rate in cattle was determined by generally accepted coprological flotation methods, as well as by native smears with further staining according to Ziehl-Nielsen. We also considered clinical signs of cryptosporidiosis (diarrhea, dehydration).Results and discussion. We established the widespread occurrence of cryptosporidiosis in cattle on the farms of the Igrinsky, Uvinsky, Zavyalovsky Districts of the Udmurt Republic. The infection rate ranged from 20.25 to 80.0%. The largest percentage of infected calves was observed in the winter-spring period which was associated with the synchronization of the reproductive cycles of cows and a decrease in the resistance of the animal organism. Toltarox 5% and Galokur drugs in work environments showed 100% extense-effectiveness. It is not recommended to apply Amprolium 25% on these farms due to the low efficacy and the development of parasite resistance to this drug.

Influence of early spring feeding on the development of bee families in the natural lands of Polissya

To ensure intensive early spring development of bee colonies in the natural lands of Polissya Zhytomyr region in the winter-spring period it is necessary to feed stimulating food. Therefore, the aim of the work is to study the influence of spring feeding with sugar-honey dough on the development and honey productivity of bee families of Ukrainian breed in conditions of clean and radioactively contaminated natural lands of Zhytomyr Polissya. The influence of feeding bee colonies with sugar-honey dough (powdered sugar, centrifuged honey, water) using pure and radioactively contaminated honey on the intensity of development and honey productivity was studied. To do this, two groups were created with experimental families of Ukrainian bee breeds, selected on the principle of analogs, one of which was in a radioactively clean area, and the other in radioactively contaminated soils 137 Cs within 15 Ki/km² and above. A comparative assessment of the early spring development of families was made: from March 16 to May 20, with an interval of 21 days, the number of open and sealed brood, egg production of queens during the honey harvest season was determined. Honey productivity at the honey harvest from natural lands was determined by the amount of honey obtained in spring and summer. Early spring feeding with sugar-honey dough promotes intensive development of families, and the content of radioactively contaminated honey does not have a negative impact on their development. After the end of the season of honey collection from natural lands, bee families of Ukrainian breed, both in the radioactively contaminated and clean zone, had a medium strength and could successfully overwinter.

ANALYSISOF FULL VALUE FEEDING OF MARAL STAGS IN WINTER AND SPRING

The productivecharacteristics of marals largely depend on the level, full value and balance of feeding. Provided these factors are taken into account, marals maximize their genetic potential. The experimental part of the study was carried out on the farm of the SPK PZ “Abayskiy”of the Ust-Koksinskiy District of the Republic of Altai in 2020. The research goal was to evaluate the full value of feeding maral stags in winter and spring period. It was found that the best energy feed was oat grain which contained 0.9 energetic feed units. When evaluating the mineral composi-tion, it may be seen that legume hay is superior to other forages in terms of calcium content. Oat grain contains larger amount of phosphorus, haylage –larger amount of magnesium. The maral stag diet usedin the SPK PZ “Abayskiy”contains mainly cereals (oats). As a result, in terms of energy nutritional value, it exceeds the upper threshold of the standard by 23%. There is phosphorus deficit by 5.2%. The content of digestible protein, sugar and carotene is higher than in the standard by 1.2, 8 and 69%, respectively. It has been found that on a daily basis, roughage (legume hay) is the largest part of the diet -7 kg per head; there is less succulent forage (silage) and less concentrates (oats). It should be noted that this diet for maral stag during the stall period requires adjustment; if possible, the proportion of hay in the diet should be re-duced; the diet should include enriched mineral supple-ments of natural origin.

Assessment of the ecological state of Kazan surface waters

The study of the influence of technogenesis on the state of surface waters in urbanized areas is one of the most urgent ecological and social problems. For processing and analysis of hydrochemical indicators of surface water bodies of Kazan for the period 2014–2020 the generally accepted stasticial indicators, as well as the methods of multivariate statistics were used. Hydrochemical models were built using the ArcGisMap software package. The data were grouped using the cluster analysis method separately for each hydrological season with the allocation of 6 groups of hydrochemical components in relation to the maximum permissible values. It has been revealed that the minimum technogenic load on the surface waters of the city falls on the spring period. Based on the analysis of the results obtained, an ecological and hydrological assessment of the state of surface waters was carried out. It was showed that the water bodies of Kazan are classified as unfavorable water bodies.

Screening of potential donors for immunoglobulins M and G to new coronavirus infection

This study presents the results of the examination of potential donors of blood and its components for immunoglobulins M and G to patients with coronavirus disease 2019 (COVID-19) living in St. Petersburg. A total of 6782 people aged 1824 years were evaluated, which accounted for 2.07% of the regions population (326 760 people) of this age group. The study was carried out in the spring and autumn of 2020. A negative result (absence of antibodies) was obtained in 93.5% of the participants. The rates of immunoglobulins M and M + G were 0.58% and 4.18%, respectively, in the spring and autumn. Moreover, the number of participants who had immunoglobulins M and G + M in the autumn period was four times higher than the indicators of the spring period, which indicated greater infection activities in the population during this period. This is most likely due to the active movement of the population in the summer. When comparing the rates of COVID-19 infection and the frequency of occurrence in donors of the same age, markers of human immunodeficiency virus 1 and 2 and hepatitis B and C in 2020 (0.024, 0.012 and 0.13%, respectively) indicate the urgency of the problem of donor selection during blood services, especially during a difficult epidemiological situation because of COVID-19. Along with organizational measures for the selection of donors (e.g., attracting individuals from organized groups in which there are no signs of an unfavorable epidemiological situation to donation), mandatory testing of potential donors for immunoglobulins M and G should be considered.

Extraseasonal Production in a Soilless System and Characterisation of Landraces of Carosello and Barattiere (Cucumis melo L.)

Barattiere and Carosello are typical melon (Cucumis melo L.) landraces of Puglia’s (Southern Italy) biodiversity. Their unripe fruits are locally consumed as an alternative to cucumbers (C. sativus L.) and are appreciated for their qualitative profile. Nevertheless, they are underutilized crops. For the high variability and confusing denominations, a morphological characterization is essential to discriminate and valorise landraces; additionally, it is fundamental to implement the agronomic technique to allow the cultivation outside the natural growth period (summer) by soilless cultivation. Two genotypes of Barattiere (‘Allungato’ and ‘Tondo’), two of Carosello (‘Scopatizzo’ and ‘Tomentoso’ (CAT)) and two of cucumber (‘Baby Star’ and ‘Modan’ hybrids) were vertically grown in the winter-spring period in a rockwool soilless system in a glasshouse with supplemental light. Landraces were characterized by morpho-physiological descriptors of melon; fruit biometrics and colour were analysed for all genotypes; productive parameters, leaf fluorescence, and chlorophyll content were measured. Genotypes varied in seeds, stem, leaf, fruit traits and they were andromonoecious; Carosello flowered earlier and produced more than Barattiere; CAT fruits were hairy and elongate, while other genotypes tended to rounder and glabrous fruits. Although landraces grew slower than cucumbers, both produced marketable fruits and the production of Carosello was comparable to cucumbers. In conclusion, Barattiere and Carosello have a productive potential and one vertically trained stem in a soilless system is appropriate for their extra-seasonal production.

The efficacy of specific immunocorrection drugs against ovine oestrosis

The purpose of the research is to characterize the effect of specific immunocorrection drugs on the survival rate of the sheep botfly larvae and the immune response of the host organism. Materials and methods. Three variants of laboratory samples of specific immunocorrection drugs against sheep oestrosis have been developed based on water-soluble proteins of Oestrus ovis L. and Lucilia serricata Mg. larvae. The studies were carried out on 12 test and 3 control groups of lambs born in the current year artificially infected with 80 larvae of the sheep botfly. Fourteen days before infection, the test lambs were immunized with the prepared drugs. The drugs were injected subcutaneously in various doses (2–6 ml) and repeatedly (1–3) or by a single intranasal irrigation at a dose of 10 ml per animal. The efficacy was evaluated for the early (July – September) and summer-spring (August – April) periods of parasitism. In the test and control animals, we determined specific antibodies (JgG), stable E-rosette-forming cells (sE-RFC) and antigen-reactive (AR-RFC) T-lymphocytes. Results and discussion. The tested specific immunocorrection drugs based on somatic proteins of the sheep botfly and the sheep green bottle larvae have a pronounced protective effect against ovine oestrosis. In experiments, being affected by various drug variants, 44.6–99.1% of the sheep botfly larvae died in the early period of parasitism, and 22.6–88.1% of the sheep botfly larvae died in the summer-spring period. Subcutaneously injected drugs stimulate the produced specific antibodies and activate the effector function of the T-cell immune system to a greater extent than intranasal irrigation.

Entrusted norms: security, trust, and betrayal in the Gulf Cooperation Council crisis

Combining scholarship on norms and trust in International Relations, this article puts forward the concept of entrusted norms as a novel means to understand certain dynamics of cooperation and conflict in international politics. Entrusted norms differ from non-entrusted norms both in the manner that they are policed and in the reaction to their infringement. In the first case, there are few formal hedging mechanisms taken against potential defection. In the second case, when broken, they result in a betrayal reaction where a return to the behavioral status quo is insufficient to return to the political status quo. We illustrate the analytical usefulness of entrusted norms through an examination of the established norms of diplomacy within the Gulf Cooperation Council, paying particular attention to interactions between Saudi Arabia and Qatar in the post-Arab Spring period. We argue that the perception of Qatar’s defection from an entrusted norm, the preservation of individual and collective dignity, contributed to the 2014 diplomatic rupture between these two states and set in motion a betrayal/attempted reconciliation cycle, where even Qatar’s attempts to move back to the behavioral status quo prior to the fallout have been insufficient to fully repair the relationship. In addition to providing a novel interpretation to this case, this paper highlights the need for further theoretical consideration of the severity and duration of punishment after norm transgression within social constructivism, reinforces the theoretical connection between social structures and emotions, and advocates for an expansion in the domains of trust that we study.

Modeling on 137Cs Radioactive Dispersion in Gosong Coast as The Candidate Location for Nuclear Power Plant

The study of radioactive dispersion in the ocean should be conducted to prepare the construction of nuclear power plant (NPP) in Gosong Coast, West Kalimantan. This study estimated the distribution of 137Cs radioactive from various scenarios of radioactive waste dumping if nuclear emergency is occurred during NPP’s operation. These scenarios were distinguished based on their volume discharges of radioactive waste into the ocean, included 10 m3 (Scenario I), 50 m3 (Scenario II), and 100 m3 (Scenario III). Model dispersions were constructed for 15 days by Delft3D-Flow module. The simulation showed that ocean current directions were not significantly different among spring and neap tide, instead the ocean current during the spring period dominantly increased rather than neap period. Ocean currents at Gosong Coast flowed parallel to the shoreline towards Singkawang Coastal Area during ebb tide. Meanwhile, during flood tide, ocean currents at Gosong Coast flowed offshore through Burung Archipelagic. The dispersed model showed the distribution of 137Cs radioactive for 15 days reaching to coastal areas of Burung Archipelagic, Singkawang, and Southern Sambas Coast. Each scenario of the disposal system did not influence the marine pollution of the West Kalimantan Sea.

Phenetics of the rock pigeon (Columba livia) plumage coloration in Orenburg

Birds differ from larger representatives, for example: mammals from the point of studying the class of birds. The following things are considered: data on hair dryers of coloring, patterns of feather cover, structure and coloring of the beak, flapping of the legs. Representatives of the class of birds, in particular synanthropic blue pigeons, have signs: features of trophic behavior and polymorphism. The paper describes distribution and main morphs of blue pigeons on the territory of Orenburg. The blue pigeon ( Columba livia ) is one of the most widespread ancient representatives, which is prone to migrations and has an extensive habitat around the world, and in urban conditions is one of the most frequently observed objects. Pigeons on the territory of Orenburg are represented by different morphs: white, black, black-stamped, brown and blue. On the territory of the Central District, during two periods, 1650 individuals of birds (1040 in spring, 610 in autumn) of different color morphs were identified, with a large predominance of black-stamped and brown. During the spring period the maximum number of birds and morphemes was high and during the autumn period the population decreased in number, as well as the ratio of the number of color morphemes. The observations were carried out in the Central District of Orenburg on three streets: March 8th, Tereshkova, Pobedy Avenue. 35 morphemes were identified in the Central District: 21 in spring and 14 in autumn. Spring morphemes in groupings, as well as their increase, were explained by combinative variability (that is due to increased reproduction in the spring period) and manifestation of recessive traits in the phenotypes of plumage coloring. Autumn morphemes were few in number; as a result, the loss is explained by a weak stability of certain color morphemes to environmental factors.