Kumis therapy for gastrointestinal diseases

1937 ◽  
Vol 33 (9) ◽  
pp. 1058-1064
Author(s):  
E. S. Kharizomenova
Keyword(s):  
Gastrointestinal Tract ◽  
Pulmonary Tuberculosis ◽  
Closed Form ◽  
Gastric Juice ◽  
Gastrointestinal Diseases ◽  
High Acidity

In 1933, the Nikolaev kumis-treatment sanatorium was admitted along with patients with stomach disease and closed form of pulmonary tuberculosis (open forms of tuberculosis are not accepted at all), as well as patients with diseases of the gastrointestinal tract, accompanied by both low and high acidity of gastric juice.

scholarly journals Abdominal syndrome in pulmonary tuberculosis

2021 ◽  
Vol 30 (9) ◽  
pp. 839-843
Author(s):  
N. M. Zakharov
Keyword(s):  
Gastrointestinal Tract ◽  
Pulmonary Tuberculosis ◽  
Digestive System ◽  
Diagnostic Errors ◽  
Gastrointestinal Diseases ◽  
The Other ◽  
Gastrointestinal Disorders ◽  
System Function ◽  
Anatomical Changes ◽  
The Subject

A large number of works that have appeared in recent years in our and foreign literature on the subject of tuberculous intestinal diseases can be explained mainly by the exceptional importance of the gastrointestinal tract behavior in tbc patients and, on the other hand, by the frequency of this suffering. Most of these works concern the clinic of tuberculous lesions of the intestine with a definite pathological and anatomical substrate at the base. However, disorders of digestive system function in patients with pulmonary tuberculosis can occur without the presence of any anatomical changes and dyspeptic disorders observed in these cases, extremely diverse in their clinical picture, not seldom present exceptional difficulty in recognizing the true causes of gastrointestinal disorders. Passing under the mask of a variety of gastrointestinal diseases, they can give rise to diagnostic errors.

ANTICYTOKINE ACTIVITY OF THE PROTOZOA BLASTOCYSTIS SPP

2020 ◽  
pp. 44-48
Author(s):  
Bugero N.V. ◽  
Ilyina N.A. ◽  
Aleksandrova S.M.
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Diseases ◽  
Control Group ◽  
Ulcer Disease ◽  
Cytokine Balance ◽  
High Prevalence ◽  
Blastocystis Spp ◽  
High Level ◽  
Eukaryotic Organisms ◽  
High Degree

In addition to the classical pathogens, which are well understood and well identified, new pathogens with the potential to spread epidemiologically are being identified. Some of these little-known organisms are the simplest Blastocystis spp. blastocystostosis. The clinical significance of Blastocystis spp. and its pathogenicity are still under discussion. This parasite belongs to a group of single-celled eukaryotic organisms living in the colon of the human intestine. Blastocystis spp. is known to be found both in people with reduced immune status and in individuals without any clinical manifestation. It has been established that a sufficiently high degree of invasiveness is observed in persons with gastrointestinal tract diseases, dermatosis, allergic reactions, in patients with carriers of the human immunodeficiency virus, etc. Possessing persistence factors, protozoa blastocysts contribute to the inactivation of host defensive mechanisms, providing a stable anthogonistic effect. In recent years, many works have been devoted to the characteristics of the persistent properties of Blastocystis spr., however, individual properties of blastocysts, in particular, anticytokine activity (ACA), have not yet been studied. In this regard, the work studied the anticytokine activity of microorganisms isolated from healthy subjects and patients with gastrointestinal tract diseases. A high prevalence of the studied characteristic in the subjects was shown. The expression of anticytokine activity in the obtained isolates of blastocysts was the highest in the group of persons with gastric ulcer disease, which decreased in the order of duodenal ulcer, chronic cholecystitis, chronic gastritis, etc. The data obtained in this work on the high level of ACA expression in blastocyst isolates obtained from individuals with gastrointestinal diseases as compared with the control group enables to conclude that their exometabolites may influence the local cytokine balance [1], which supports the inflammatory process.

scholarly journals Eosinophilic Gastrointestinal Diseases: Review and Update

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Mahreema Jawairia ◽  
Ghulamullah Shahzad ◽  
Paul Mustacchia
Keyword(s):  
Gastrointestinal Tract ◽  
Clinical Features ◽  
Gastrointestinal Symptoms ◽  
Gastrointestinal Diseases ◽  
Gastrointestinal Disorders ◽  
Diverse Group ◽  
Intestinal Diseases ◽  
Gastrointestinal Inflammation ◽  
Eosinophilic Gastrointestinal Disorders

Eosinophilic gastrointestinal disorders (EGIDs) are a progressively more frequent diverse group of intestinal diseases. The intention of this paper is to present the newest developments in the care of patients with EGIDs and to sum up a rising literature defining the clinical features and mechanistic elements of eosinophils and their intricate associations with the gastrointestinal tract. Clinicians ought to stay sensitive to EGIDs as a diagnostic likelihood for patients with general gastrointestinal symptoms. Further research is warranted to establish various methods leading to dysfunction coupled with eosinophilic gastrointestinal inflammation.

Histopathological study of gastrointestinal endoscopic biopsies in pediatric patients

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Faten A Ghazal ◽  
Wesam M Osman ◽  
Sarah A Hakim ◽  
Nada N Tamem
Keyword(s):  
Inflammatory Bowel Disease ◽  
Helicobacter Pylori ◽  
Celiac Disease ◽  
Gastrointestinal Tract ◽  
Gastrointestinal Diseases ◽  
University Hospital ◽  
Gastrointestinal Lesions ◽  
Different Types ◽  
Inflammatory Bowel ◽  
Gastrointestinal Inflammation

Abstract Background Non neoplastic GI lesions in pediatrics are variable and differ in types and prevalence among each pediatric age group. Helicobacter pylori is an important pathogen that can cause gastritis and peptic ulcers in adults as well as in children. Celiac disease is a gluten-dependent autoimmune disorder which affects individuals having genetic susceptibility. Eosinophilic gastrointestinal diseases are disorders that primarily affect the gastrointestinal tract with eosinophil-rich inflammation in the absence of known causes for eosinophilia. Inflammatory bowel disease (IBD) is a chronic inflammatory disorder, mainly affecting the gastrointestinal tract with extraintestinal manifestations and associated immune disorders. It seems that it is one of the most common gastrointestinal diseases affecting children in the developed countries. Aim of the work To study different types of paediatric non neoplastic gastrointestinal lesions from gastrointestinal endoscopic biopsies received at the Pathology Department in Ain Shams University hospital during a period of 2 years (2017-2018), and to correlate them with the clinicopathological presentations and endoscopic findings. Patients and Methods A cross sectional study was conducted on all pediatric gastrointestinal biopsies received at Pathology Department in Ain Shams University Hospital during the period of two years (2017- 2018). Only cases with information for all the covariates (n = 580) were selected and the results were statistically analyzed. Results Total 580 pediatric cases were enrolled according to inclusion criteria. Nonspecific gastrointestinal inflammation represented (47.1%), Helicobacter pylori associated gastrointestinal inflammation represented (43.5%), Eosinophilic gastrointestinal disease represented (3.8%), Inflammatory bowel disease (IBD) represented (3.7%), Celiac disease represented (1.9%). Conclusion This is the first study conducted in Ain Shams University Hospitals to assess the different types of pediatric non neoplastic gastrointestinal lesions received with clinicopathological and endoscopic correlation. The most common pediatric non neoplastic GI lesion is Helicobacter pylori infection. The diagnosis of pediatric non neoplastic GI disorder necessitates interdepartmental teamwork between GI pediatricians and pathologists.

scholarly journals Epidemiological study of the prevalence of cystitis in women of the Voronezh region

2021 ◽  
Vol 14 (2) ◽  
pp. 10-18
Author(s):  
O.I. Apolikhin ◽  
◽  
Florian Wagenlehner ◽  
D.A. Voytko ◽  
O.V. Zolotukhin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Tract ◽  
Epidemiological Study ◽  
Gastrointestinal Diseases ◽  
Study Group ◽  
General Group ◽  
Statistical Tool ◽  
Voronezh Region ◽  
History Of ◽  
Group 2

Introduction. The article is devoted to an epidemiological study of the prevalence of cystitis and risk factors for recurrence this disease. Materials and methods. The study is based on the data obtained during the screening survey of 1014 women in the age group of 18-80 years old, permanently residing in the Bobrovsky district of the Voronezh region. Based on the age of the subjects, 3 groups were formed: Group 1 (general group) - 1014 women, Group 2 (fertile age) - 551 women, Group 3 (postmenopausal age) - 463 women. To study the influence of risk factors on the development of cystitis, the following criteria were used: antibiotic therapy, sex life, urinary disorders, gastrointestinal tract (GIT) dysfunction, etc. The obtained material was processed using the computer program Statistics 10.0. 𝛘2 was used as a statistical tool. Results. Of the total number of women surveyed, 15.3% had risk factors according to the ORENUC classification system based on the clinical picture of UTI, anatomical level of UTI, the severity of infection, classification of risk factors and the availability of appropriate antimicrobial therapy. The largest number of risk factors was found in postmenopausal patients (p <0.05). It was found that despite the fact that most of the subjects were sexually active, the absence of sexual activity and the presence of one sexual partner did not affect the presence of a history of cystitis episode (p> 0.05), however, it was revealed that the history of cystitis was significantly associated with functions of the gastrointestinal tract (p<0.05). The use of tactics aimed at active detection of cystitis, by means of questionnaires, can increase the detection rate of cystitis by 10 times. Discussions. In our study, we did not find a large number of cases of recurrent cystitis, in contrast to previously published works, which cited figures from 10 to 30% of the number of women, however, by means of questionnaires, we managed to deduce the prevalence of cystitis in the studied region in women over 18 years old. which amounted to 17.4%. The figure obtained is consistent with data published in previously papers. Conclusions. TThis study has confirmed the previously published works indicating the relationship of cystitis with gastrointestinal diseases. In addition, we found that the prevalence of cystitis (having one or more episodes during a lifetime) in the study group was 17.4%. The annual incidence of cystitis in the study group was 3.2%, while according to official statistics in the region it does not exceed 0.4%. The latter fact indicates the need for further research and strengthening of sanitary and edu- cational work among the population (Internet, TV, radio, newspapers, etc.).

scholarly journals IDENTIFICATION MARKERS OF INFECTION DUE TO C. TRACHOMATIS AND C. PNEUMONIAE, IN PATIENTS WITH DISEASES OF THE GASTROINTESTINAL TRACT

2018 ◽  
Vol 8 (3) ◽  
pp. 316-324
Author(s):  
N. E. Bondareva ◽  
E. Yu. Morgunova ◽  
N. A. Zigangirova ◽  
Yu. G. Shapkin ◽  
Yu. V. Chalyk ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Blood Serum ◽  
Chlamydial Infection ◽  
Simultaneous Detection ◽  
Gastrointestinal Diseases ◽  
Infectious Period ◽  
Gastrointestinal Pathology ◽  
Causative Agents ◽  
Focus Of Infection ◽  
Primary Focus

 To date, clinical data have convincingly shown that C. trachomatis and C. pneumoniae infectious can cause serious diseases with severe complications and consequences. There are assumptions that the developed chronic chlamydial infection can become an important factor in the pathogenesis of the gastrointestinal tract diseases, which are manifested in the so-called post-infectious period. It is commonly known that chlamydial infection has a tropism to the cylindrical epithelium, which covers the human mucous membrane of the urethra, cervix, rectum, conjunctiva of the eyes and the throat. However, the role of the causative agents of chlamydial infections, such as C. trachomatis and C. pneumoniae, in the occurrence of the gastrointestinal tract diseases has not been studied. In order to study the possible relationship between the gastrointestinal diseases and the presence of chlamydial infection markers, we have selected a group of patients with the gastrointestinal diseases and detected antibodies to C. trachomatis and C. pneumoniae and DNA of these pathogens in blood serum, liver biopsy and bile ducts. As a result, C. trachomatis DNA in blood serum was detected in 50% of cases, and in liver biopsies — in 59.3%. A new approach has been developed in the serological diagnosis of chlamydial infection caused by C. trachomatis, which allowed for revealing diagnostic antibody titers in 51.9% of cases in this group of patients, and in the comparison group — in 11.6% of cases. Among 50% of patients, in whom DNA was revealed in blood serum, it was also revealed in 64.3% of cases in biopsy samples of gastrointestinal organs. Upon detection of C. trachomatis DNA in blood serum, antibodies to the “cultural” antigen were detected in 60.1% of cases, and with the simultaneous detection of C. trachomatis DNA in blood serum and gastrointestinal organs, they were found in 72.2% of cases. Simultaneous detection of C. trachomatis, both in blood serum and in the gastrointestinal tract, may indicate the ability of C. trachomatis to spread hematogenously and infect organs away from the primary focus of infection. The obtained data absolutely require further study in light of the identification of the relationship between the detection of the pathogen and the development of the gastrointestinal pathology. But in general, the results are not yet studied evidence of the possible gastrointestinal organs infection by C. trachomatis.

scholarly journals Somatostatin and gastrointestinal tract. Clinical experiences

2013 ◽  
Vol 154 (39) ◽  
pp. 1535-1540 ◽  
Author(s):  
László Herszényi ◽  
Emese Mihály ◽  
Zsolt Tulassay
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Hormones ◽  
Gastrointestinal Diseases ◽  
Somatostatin Analogues ◽  
Therapeutic Modality ◽  
Exocrine Function ◽  
Somatostatin Analogue ◽  
Clinical Experiences ◽  
Pancreatic Fistulas ◽  
Long Acting

The effect of somatostatin on the gastrointestinal tract is complex; it inhibits the release of gastrointestinal hormones, the exocrine function of the stomach, pancreas and bile, decreases motility and influences absorption as well. Based on these diverse effects there was an increased expectation towards the success of somatostatin therapy in various gastrointestinal disorders. The preconditions for somatostatin treatment was created by the development of long acting somatostatin analogues (octreotide, lanreotide). During the last twenty-five years large trials clarified the role of somatostatin analogues in the treatment of various gastrointestinal diseases. This study summarizes shortly these results. Somatostatin analogue treatment could be effective in various pathological conditions of the gastrointestinal tract, however, this therapeutic modality became a part of the clinical routine only in neuroendocrine tumours and adjuvant treatment of oesophageal variceal bleeding and pancreatic fistulas. Orv. Hetil., 2013, 154, 1535–1540.

Disorders of mineral bone density and vitamin D deficiency in chronic diseases of the gastrointestinal tract

2015 ◽  
Vol 21 (31) ◽  
pp. 28-32
Author(s):  
Тотров ◽  
Igor Totrov ◽  
Слохова ◽  
N. Slokhova ◽  
Медоева ◽  
...  
Keyword(s):  
Vitamin D ◽  
Gastrointestinal Tract ◽  
Bone Density ◽  
Blood Serum ◽  
Vitamin D Deficiency ◽  
Chronic Diseases ◽  
Gastrointestinal Diseases ◽  
High Prevalence ◽  
Mineral Bone Density ◽  
Different Parts

This article presents the results of a study of mineral bone density, and vitamin D 25(OH)D3 in serum of 100 patients with chronic diseases of the stomach and duodenum. The results osteodensitometry studies have demonstrated a high prevalence of osteopenia and osteoporosis in different parts of the skeleton among the patients with diseases of the gastrointestinal tract. The decrease of vitamin D level in the blood serum of patients with diseases of the stomach and duodenum. The existing disorders of bone metabolism in patients with gastrointestinal diseases are connected with deficiency of vitamin D.

scholarly journals Viruses causing frequent and emergent gastrointestinal infections of cattle (review)

2021 ◽  
Author(s):  
K.P. Yurov ◽  
M.I. Gulyukin ◽  
L.A. Mnikova ◽  
S.V. Alexeyenkova ◽  
T.A. Ishkova
Keyword(s):  
Gastrointestinal Tract ◽  
Causative Agent ◽  
Molecular Genetic ◽  
Small Ruminants ◽  
Gastrointestinal Diseases ◽  
Gastrointestinal Infections ◽  
Enveloped Virus ◽  
Antigenic Properties ◽  
Wide Range ◽  
Newborn Calves

Pestiviruses are a common causative agent of gastrointestinal infections in calves. Viruses infect a wide range of domestic and wild animals, cause pathology of the gastrointestinal tract, respiratory, reproductive organs, and the immune system. According to the modern classification, the genotype of pestiviruses is designated by the letters of the Latin alphabet: A, B, C, etc. Common pestivirus infections include viral diarrhea-mucosal disease (VD-MD). The causative agent is pestivirus of genotypes A and B. The virus of genotype A is represented 20 subtypes (1a-1t) and three subtypes (2a-2c). The type A virus in newborn calves causes diarrhea with profuse watery discharge, dehydration. Infection of the type B virus is characterized by a malignant course of the disease in the form of fever, hemorrhagic inflammation of the gastrointestinal tract, and high mortality. In 2004, pestivirus infection of small ruminants was registered for the first time in several countries, caused by an atypical pestivirus, designated as Hobi virus, type D. respiratory organs in calves. Common pathogens include bovine coronavirus (cattle) from the Coronaviridae family, order Nidovirales, subgroup 2a. There are three forms of cattle coronavirus infection: diarrhea of newborn calves; winter diarrhea with the hemorrhagic syndrome in cows and transport fever. A disease similar in symptomatology is caused by rotaviruses. According to the antigenic properties of the main proteins, rotaviruses are divided into groups, subgroups, and serotypes. The main pathogens for calves are group A rotaviruses. Rotavirus diarrhea occurs in newborn calves in the first three weeks. Modern immunological, molecular genetic methods have made it possible to identify new enteropathogenic cattle viruses. Among them, norovirus, the causative agent of a highly contagious anthropozoonotic disease with a fecal-oral transmission mechanism, belongs to the Caliciviridae family, the Norovirus genus, genogroups III and V. Some viruses that cause gastrointestinal diseases are isolated both from sick calves and from animals without visible signs of the disease. Other pathogens are Nebovirus, a non-enveloped virus, a member of the Caliciviridae family, Cattle Torovirus, an enveloped virus of the Coronaviridae family, Astroviruses, a non-enveloped virus of the Astroviridae family. The family consists of the genera: Mamastrovirus mammals and Avastrovirus birds. Cattle picornaviruses, represented by kobuvirus (also called aichivirus B), belongs to the genus Enterovirus in the Picornaviridae family, found in the feces of calves with diarrhea. At the same time, other components of the microbiome of the gastrointestinal tract of calves: bacteria, fungi, rickettsiae - complicate viral infections or, on the contrary, have antiviral properties.

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