Depression in young HIV-positive patients is associated with anemia

Aim. To examine the interrelation between depression and anemia in HIV-positive patients. Methods. A cross-sectional study included 99 HIV-positive patients. Anemia was defined as hemoglobin concentration below 12 g/dL in women and 13 g/dL in men. Depressive symptoms were measured using the Beck Hopelessness Scale. Results. Anemia was registered in 30.3% of patients. In 54.5% of patients depression was detected (Beck Scale score ≥10). In patients with anemia the prevalence of depression was 76.7% including severe depression in 20% of patients. Mean Beck Scale score in anemia group was significantly higher compared to the group without anemia (17.57±12.90%, 95% confidence interval 13.5-20.5 and 10.06±8.07, 95% confidence interval 7.7-12.3, t=3.2, p=0.007 relevantly). Moderate reverse correlation between Beck scale scores and hemoglobin level was revealed ((r=-0.24, p=0.019). After stratification and adjusting for potential confounders, anemia was found to be associated with higher prevalence of depression in patients younger than 40 years old. The prevalence ratio for depression in patients with anemia, comparing to patients without anemia was 1.827 (95% confidence interval 1.28-2.61, λ2=8.85, p=0.0029) in this age group. Detected association did not depend on sex, family status, disease duration, CD4-level and treatment with antiretrovirals. Conclusion. Depressive symptoms are associated with anemia in HIV-patients younger than 40 years old.

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Depression in Primary Caregivers of Patients Listed for Liver or Kidney Transplantation

Progress in Transplantation ◽

10.1177/152692480701700306 ◽

2007 ◽

Vol 17 (3) ◽

pp. 193-198 ◽

Cited By ~ 11

Author(s):

Ahmed Bolkhir ◽

Marci M. Loiselle ◽

Donna M. Evon ◽

Paul H. Hayashi

Keyword(s):

Kidney Transplantation ◽

Scale Score ◽

Depression Scale ◽

Primary Caregivers ◽

Severe Depression ◽

Epidemiologic Studies ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Prevalence Of Depression ◽

The Impact

Background No studies have examined depression in primary caregivers of adult patients listed for liver or kidney transplantation. Objective To determine the prevalence of depression among primary caregivers of patients listed for liver or kidney transplantation and to compare these 2 groups. Design A cross-sectional survey was conducted. The Center for Epidemiologic Studies Depression Scale and a demographic questionnaire were sent out and returned by mail. Results Of 72 eligible primary caregivers, 42 (58%) participated; the participation rate was similar for caregivers of kidney and liver failure patients (21/32 [66%)] vs 21/40 [53%], P = .3). Mean caregiver age was 54.7 ± 13.6 years. Twenty-three caregivers (54.8%) were spouses, 15 (35.7%) were first-degree relatives, and 26 (62%) were women. Median depression scale score was 5.5 (0–36). Three (7%), 2 (5%), and 3 (7%) participants reported mild, moderate, and severe depression, respectively. Median Center for Epidemiologic Studies Depression Scale score was higher among caregivers of liver versus kidney patients, but the difference was not statistically significant (9 vs 4, P = .2). Depression scale scores did not correlate with age, sex, time listed, or nature or length of relationship with the patient. The prevalence of depression in primary caregivers was 19%; of these caregivers, one third may have had severe depression. Conclusions The prevalence of moderate to severe depression in primary caregivers of liver and kidney transplant candidates is significant. The impact of depression on caregivers as well as patients, both before and after transplantation, deserves study. Screening for depression in caregivers could lead to clinical interventions that benefit caregivers and indirectly improve patient outcomes.

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Association of severity of depressive symptoms with sleep quality, social support and stress among Pakistani medical and dental students: A cross-sectional study

Global Psychiatry ◽

10.2478/gp-2019-0019 ◽

2019 ◽

Vol 2 (2) ◽

pp. 211-220

Author(s):

Ahmed Waqas ◽

Aqsa Iftikhar ◽

Zahra Malik ◽

Kapil Kiran Aedma ◽

Hafsa Meraj ◽

...

Keyword(s):

Social Support ◽

Depressive Symptoms ◽

Medical Students ◽

Sleep Quality ◽

Severe Depression ◽

Dental Students ◽

Poor Sleep ◽

Poor Sleep Quality ◽

Cross Sectional ◽

Medical And Dental Students

AbstractObjectivesThis study has been designed to elucidate the prevalence of stress, depression and poor sleep among medical students in a Pakistani medical school. There is a paucity of data on social support among medical students in Pakistan; an important predictor of depressive symptoms. Therefore, this study was also aimed to demonstrate the direct and indirect impact of social support in alleviating depressive symptoms in the study sample.MethodsThis observational cross-sectional study was conducted in Lahore, Pakistan, where a total of 400 students at a medical school were approached between 1st January to 31st March 2018 to participate in the study. The study sample comprised of medical and dental students enrolled at a privately financed Pakistani medical and dental school. The participants responded to a self-administered survey comprising of five parts: a) demographics, b) Pittsburgh Sleep Quality Index (PSQI), c) Patient Health Questionnaire-9 (PHQ-9), d) Multidimensional Scale of Perceived Social Support (MSPSS) and e) Perceived Stress Scale-4 (PSS-4). All data were analysed using SPSS v. 20. Linear regression analysis was used to reveal the predictors of depression.ResultsIn total, 353 medical students participated, yielding a response rate of 88.25%. Overall, poor sleep quality was experienced by 205 (58.1%) students. Mild to severe depression was reported by 83% of the respondents: mild depression by 104 (29.5%), moderate depression by 104 (29.5%), moderately severe depression by 54 (15.3%) and severe depression by 31 (8.8%) respondents. Subjective sleep quality, sleep latency, daytime dysfunction and stress levels were significantly associated with depression symptoms. Social support was not significantly associated with depressive symptoms in the regression model (Beta = -0.08, P < 0.09); however, it acted as a significant mediator, reducing the strength of the relationship between depressive symptoms and sleep quality and stress.ConclusionsAccording to our study, a large proportion of healthcare (medical and dental) students were found to be suffering from mild to moderate depression and experienced poor sleep quality. It is concluded that social support is an important variable in predicting depressive symptomatology by ameliorating the effects of poor sleep quality and high stress levels.

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Watching sports and depressive symptoms among older adults: a cross-sectional study from the JAGES 2019 survey

Scientific Reports ◽

10.1038/s41598-021-89994-8 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Taishi Tsuji ◽

Satoru Kanamori ◽

Ryota Watanabe ◽

Meiko Yokoyama ◽

Yasuhiro Miyaguni ◽

...

Keyword(s):

Older Adults ◽

Depressive Symptoms ◽

Geriatric Depression Scale ◽

Depression Scale ◽

Mail Survey ◽

Prevalence Ratio ◽

Average Frequency ◽

Evaluation Study ◽

Cross Sectional Study ◽

Cross Sectional

AbstractThe current study investigated the relationship between the frequency of watching sports and depressive symptoms among older adults. This study used cross-sectional data from the Japan Gerontological Evaluation Study, a nationwide mail survey of 21,317 older adults. Depressive symptoms were defined as a Geriatric Depression Scale score of ≥ 5. Participants were queried regarding the average frequency at which they watched sports on-site and via TV/Internet over the past year. Among the 21,317 participants, 4559 (21.4%) had depressive symptoms, while 4808 (22.6%) and 16,576 (77.8%) watched sports on-site and via TV/Internet at least once a year, respectively. Older adults who watched sports on-site a few times/year (prevalence ratio, 0.70; 95% confidence interval, 0.65–0.74) or 1–3 times/month (0.66, 0.53–0.82) were less likely to have depressive symptoms compared to non-spectators after adjusting for frequency of playing sports, exercise activities, and other potential confounders. Meanwhile, a dose–response relationship was confirmed for watching via TV/Internet (prevalence ratio of 0.86, 0.79, and 0.71 for a few times/year, 1–3 times/month, and ≥ 1 time/week, respectively). This study suggested that watching sports on-site or via TV/Internet, regardless of whether they regularly engage in sports, may reduce the risk of depressive symptoms among older adults.

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AB1192 THE UNDERWORLD OF DEPRESSIVE SYMPTOMS IN RHEUMATIC DISEASES: OVERLOOKED, UNRECOGNIZED OR UNPERCEIVED?

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2020-eular.1998 ◽

2020 ◽

Vol 79 (Suppl 1) ◽

pp. 1886.2-1887

Author(s):

F. Ingegnoli ◽

T. Schioppo ◽

T. Ubiali ◽

V. Bollati ◽

S. Ostuzzi ◽

...

Keyword(s):

Depressive Symptoms ◽

Rheumatic Diseases ◽

Real Life ◽

Severe Depression ◽

Mild Depression ◽

Cross Sectional ◽

Online Study ◽

Social Burden ◽

Patient Health ◽

The University

Background:The concomitant presence of depressive symptoms and rheumatic diseases (RDs) impose a considerable economic and social burden on the communities as they are associated with numerous deleterious outcomes such as increased mortality, work disability, higher disease activity and worsening physical function, higher pain levels and fatigue. Despite growing interest on depressive symptoms burden in RDs, current patient perception on this topic is unknown.Objectives:Italian patients with RDs were invited to participate in an online study gauging the presence and the perception of depressive symptoms using the Patient Health Questionnaire (PHQ-9).Methods:This was a cross-sectional no-profit online study to screen the presence and the perception of depressive symptoms in RDs patients. All participants gave their consent to complete the PHQ-9 and they were not remunerated. Completion was voluntary and anonymous. The PHQ-9 rates the frequency of symptoms over the past 2 weeks on a 0-3 Likert-type scale. It contains the following items: anhedonia, depressed mood, trouble sleeping, feeling tired, change inappetite, guilt or worthlessness, trouble concentrating, feeling slowed down or restless, and suicidal thoughts. Patients were stratified as: <4 not depressed, 5-9 sub-clinical or mild depression, 10-14 moderate depression, 15-19 moderately severe depression and 20-27 severe depression. The survey was disseminated by ALOMAR (Lombard Association for Rheumatic Diseases) between June and October 2019.Results:192 patients took part in the study: 170 female with median age 50 years. Among respondents only 35 (18.2%) were not depressed. Depression was sub-clinical or mild in 68 (35.4%), moderate in 42 (21.9%), moderately severe in 30 (15.6%), and severe in 17 (8.9%). 16 (8.3%) of respondents declared to have depressive symptoms and 7 of 16 were under psychiatric therapy.Moreover, patients were grouped according to diagnosis.124 respondents had inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis). 23 (18.5%) were not depressed. Depression was sub-clinical or mild in 41 (33%), moderate in 26 (21%), moderately severe in 21 (17%), and severe in 13 (10.5%). Among them, 8 (6.5%) declared to have depressive symptoms depressed and 3 of 8 were under psychiatric therapy.49 respondents had a connective tissue disease or vasculitis. 11 (22.5%) were not depressed. Depression was sub-clinical or mild in 19 (38.8%), moderate in 13 (26.5%), moderately severe in 2 (4%), and severe in 4 (8.2%). Among them, 3 (6%) declared to have depressive symptoms and 1 of 6 were under psychiatric therapy.19 respondents had other rheumatic diseases. 1 (5.3%) was not depressed. Depression was sub-clinical or mild in 8 (42.1%), moderate in 3 (15.8%), moderately severe in 7 (36.8%). Among them, 5 (26.3%) declared to be depressed and 3 of 5 were under psychiatric therapy.Conclusion:Our study confirmed that the overall real-life burden of depressive symptoms is relevant in all RDs. At the same time, these results highlighted that depressive symptoms are overlook by physicians and unperceived by patients since fewer that half of respondents (46.4%) had a clinical depression (PHQ-9>10). These results suggested that screening for depression should form part of the routine clinical assessment of RD patients.Acknowledgments:We thank the Lombard Association of Rheumatic Diseases (ALOMAR) for its contribution to design and disseminate the survey, the group that sustain systemic sclerosis (GILS), and the IT service of the University of Milan.Disclosure of Interests:Francesca Ingegnoli: None declared, Tommaso Schioppo: None declared, Tania Ubiali: None declared, Valentina Bollati: None declared, Silvia Ostuzzi: None declared, Massimiliano Buoli: None declared, Roberto Caporali Consultant of: AbbVie; Gilead Sciences, Inc.; Lilly; Merck Sharp & Dohme; Celgene; Bristol-Myers Squibb; Pfizer; UCB, Speakers bureau: Abbvie; Bristol-Myers Squibb; Celgene; Lilly; Gilead Sciences, Inc; MSD; Pfizer; Roche; UCB

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Prevalence of Depression, Anxiety and Stress in Medical Students, interns and residents in Pakistan

10.53350/pjmhs211592333 ◽

2021 ◽

Vol 15 (9) ◽

pp. 2333-2336

Author(s):

Anum Arif ◽

Minahil Iram ◽

Sabih Nofal ◽

Aima Sohail ◽

Bismah Riaz ◽

...

Keyword(s):

Mental Health ◽

Medical Students ◽

Severe Depression ◽

Poor Mental Health ◽

Military Hospital ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Prevalence Of Depression ◽

Interns And Residents ◽

The Mean

Aim: To assess prevalence of Depression, Anxiety, Stress in medical students, interns, and residents in Pakistan Study design: Cross-sectional Survey (Questionnaire) based study. Place and duration of study: This study was conducted at Combined Military Hospital Lahore Medical College from March 2020 to May 2020. Results: 104 participants were included in the study. There was female predominance 58(55.8%), and the mean age was 23.55±1.42. The overall mean score of depression and anxiety was 21.2±12.67 and 15.7±10.67 respectively and most prevalent in third and fourth-year residents. The mean stress score was 13.7, 10. 27. Twenty-eight (26.9%) of the overall participants had extremely severe depression, 36 (34.6 %) had extremely severe anxiety and 13(12.5%) had severe stress. Doctors studying and practicing in the private sector have a higher DASS21 score (p = < 0.006) Conclusion: Multiple factors have been found to contribute to the poor mental health of health care workers, including financial trouble, sleep deprivation, abuse from colleagues, high expectations, female gender, broken relationships, and substance misuse. Keywords: Anxiety Disorders, Depression, Medical, Mental Health Problem Solving, Psychological Distress,

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Prevalence of Depression Symptoms and Associated Sociodemographic and Clinical Correlates Among Syrian Refugees in Lebanon

10.21203/rs.3.rs-62968/v1 ◽

2020 ◽

Author(s):

Hady Naal ◽

Dana Nabulsi ◽

Nour El Arnaout ◽

Lina Abdouni ◽

Hani Dimassi ◽

...

Keyword(s):

Mental Health ◽

Large Scale ◽

Severe Depression ◽

Depression Symptoms ◽

Syrian Refugees ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Clinical Correlates ◽

Syrian Refugee ◽

Prevalence Of Depression

Abstract Background: Since the outbreak of the Syrian war in 2011, close to 6 million Syrian refugees have escaped to Syria’s neighbouring countries, including Lebanon. Evidence suggests rising levels of mental health disorders among Syrian refugee populations. Yet, to the best of our knowledge, large-scale studies addressing the mental health of adult Syrian refugees in Lebanon are lacking. Aims: We examined the prevalence of depression symptoms, which represent a common and debilitating mental health disorder among Syrian refugee populations in Lebanon, along with their sociodemographic and clinical correlates.Methods: A cross-sectional survey design was conducted as part of a collaborative project-“Sijilli”- led by the Global Health Institute at the American University of Beirut (Beirut, Lebanon) across 4 informal tented settlements for refugees (Beirut, Bekaa, North, South) in Lebanon among adult Syrian refugees (≥18), over a period extending from 2018 to 2020. The survey inquired about participants’ sociodemographic and clinical characteristics, and screened participants for symptoms of depression through sequential methodology using the Patient Health Questionnaire (PHQ-2 and PHQ-9). Results: A total of 3255 adult Syrian refugees were enrolled in the study. Of those refugees, only 51.6% (n=1678) screened positive on the PHQ-2 and were therefore eligible to complete the PHQ-9. The PHQ-9 analysis revealed high prevalence (25%) of moderate to severe depression in the total sample, suggestive of high probability for major depression disorder (MDD). Further analyses indicate that being ≥45 years of age (OR 1.70, 95% CI 1.22-2.36), a woman (OR 1.35, 95% CI 1.07-1.69), divorced/separated (OR 3.32, 95% CI 1.57-7.01), reporting a neurological (OR 1.77, 95% CI 1.20-2.61) or a mental health condition (OR 5.30, 95% CI 2.40-11.66) are major risk factors for MDD.Conclusion: Our study suggests that one in four Syrian refugees in Lebanon have probable MDD, and our findings have important public health and clinical implications on refugee health. There is a need to enhance screening efforts, to improve access and referral to mental health services, and to improve post-migration factors among Syrian refugees in Lebanon.

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Prevalence of Depression, Anxiety and Stress in Medical Students, interns and residents in Pakistan

10.53350/pjmhs211592215 ◽

2021 ◽

Vol 15 (9) ◽

pp. 2215-2218

Author(s):

Anum Arif ◽

Minahil Iram ◽

Sabih Nofal ◽

Aima Sohail ◽

Bismah Riaz ◽

...

Keyword(s):

Mental Health ◽

Medical Students ◽

Severe Depression ◽

Poor Mental Health ◽

Military Hospital ◽

Cross Sectional Survey ◽

Cross Sectional ◽

Prevalence Of Depression ◽

Interns And Residents ◽

The Mean

Aim: To assess prevalence of depression, anxiety, stress in medical students, interns and residents in Pakistan Study design: Cross-sectional Survey (Questionnaire) based study. Place and duration of study: This study was conducted at Combined Military Hospital Lahore Medical College from March 2020 to May 2020. Results: 104 participants were included in the study. There was female predominance 58(55.8%), and the mean age was 23.55±1.42. The overall mean score of depression and anxiety was 21.2±12.67 and 15.7±10.67 respectively and most prevalent in third and fourth-year residents. The mean stress score was 13.7, 10. 27. Twenty-eight (26.9%) of the overall participants had extremely severe depression, 36 (34.6 %) had extremely severe anxiety and 13(12.5%) had severe stress. Conclusion: Multiple factors have been found to contribute to the poor mental health of health care workers, including financial trouble, sleep deprivation, abuse from colleagues, high expectations, female gender, broken relationships, and substance misuse. The prevalence of depression, anxiety, and stress in common in medical students. This calls for the development of strategies, workshops, and programs to identify modifiable stressors, encourage students to reach out to their family members and their teachers to verbalize their issues, and make psychiatric consultation accessible to them. Keywords: Anxiety Disorders, Depression, Medical, Mental Health Problem Solving, Psychological Distress,

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Risky Alcohol Consumption and Associated Health Behaviour Among HIV-Positive and HIV-Negative Patients in a UK Sexual Health and HIV Clinic: A Cross-Sectional Questionnaire Study

AIDS and Behavior ◽

10.1007/s10461-019-02714-2 ◽

2019 ◽

Vol 24 (6) ◽

pp. 1717-1726 ◽

Cited By ~ 1

Author(s):

Emmi Suonpera ◽

Rebecca Matthews ◽

Ana Milinkovic ◽

Alejandro Arenas-Pinto

Keyword(s):

Depressive Symptoms ◽

Alcohol Consumption ◽

Drug Use ◽

Questionnaire Study ◽

Hiv Positive ◽

Cross Sectional ◽

Problematic Drug ◽

Risky Alcohol ◽

Risky Alcohol Consumption ◽

Hiv Negative

Abstract Alcohol misuse has been associated with negative consequences among HIV-positive patients. Data on real prevalence of risky alcohol consumption among the HIV-positive population in the UK are lacking. A cross-sectional questionnaire study using standardised validated instruments among HIV-positive (n = 227) and HIV-negative (n = 69) patients was performed. The prevalence of risky alcohol consumption (AUDIT) and associations with depressive symptoms (PHQ-9), problematic drug use (DUDIT), adherence to ART (CASE Adherence Index), sexual behaviour and demographic characteristics were assessed among both patient groups independently. A quarter (25.1%) of HIV-positive patients and 36.1% of HIV-negative patients reported risky alcohol consumption (AUDIT-score ≥ 8). In the multivariable analysis among HIV-positive patients depressive symptoms (p = 0.03) and problematic drug use (p = 0.007) were associated with risky alcohol consumption. Among HIV-negative patients these associations were not present. Risky alcohol consumption among HIV-positive patients is prevalent, and together with depressive symptoms and problematic drug use, may influence HIV-disease progression and patients’ wellbeing.

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Back pain and depressive symptoms: A systematic review and meta-analysis

The International Journal of Psychiatry in Medicine ◽

10.1177/0091217420913001 ◽

2020 ◽

pp. 009121742091300 ◽

Cited By ~ 1

Author(s):

Sohrab Amiri ◽

Sepideh Behnezhad ◽

Esfandiar Azad

Keyword(s):

Back Pain ◽

Depressive Symptoms ◽

Confidence Interval ◽

Publication Bias ◽

Odds Ratio ◽

Meta Analysis ◽

Depression Symptoms ◽

Psychological Consequences ◽

Cross Sectional ◽

Effective Prevention

Background Low back pain is a common disorder that has many consequences. This study is an attempt to meta-analyze the risk of depression symptoms in back pain. Method Four databases were selected for review, and this search was conducted using key words. Eleven eligible articles were selected for review and meta-analysis was conducted. Subgroup analyses were continued with study design and the method of measuring depression. Also, the heterogeneity and publication bias were examined. Results Eleven cohort and cross-sectional articles are used in the meta-analysis between back pain and depressive symptoms. The odds ratio 2.07 was calculated for this relationship. In prospective-cohort studies, 1.71 (95% confidence interval = 1.24–2.36) results indicated that back pain is a risk factor for depression symptoms and in cross-sectional studies, pooled odds ratio (2.33; 95% confidence interval = 1.29–4.21) showed that back pain is associated with depression symptoms. Some degree of publication bias was not found in the study. Conclusions Back pain is an effective factor in increasing the likelihood of depression. Adoption of effective prevention and treatment approaches can play an important role in reducing the psychological consequences in these individuals.

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Prevalence of depression and associated factors among hemodialyzed patients in Jazan area, Saudi Arabia: a cross-sectional study

Mental Illness ◽

10.1108/mij-02-2020-0004 ◽

2020 ◽

Vol 12 (1) ◽

pp. 1-5

Author(s):

Asim Othayq ◽

Abdulwahab Aqeeli

Keyword(s):

Saudi Arabia ◽

Depressive Symptoms ◽

Sleep Disturbances ◽

Cross Sectional Study ◽

Cross Sectional ◽

Content Type ◽

Prevalence Of Depression ◽

Cross Sectional Design ◽

Associated Risk Factors ◽

Periodic Evaluation

Purpose This study aims to evaluate the prevalence of depression and associated risk factors among patients on hemodialysis in Jazan area, Saudi Arabia. Design/methodology/approach The study was conducted on 211 randomly selected hemodialysis patients in Jazan area, Saudi Arabia, using an observational cross-sectional design. Patients were screened for depressive symptoms using the depression, anxiety and stress scale 42 (DASS-42). Descriptive statistics were used to present sociodemographic data. Multiple logistic regression was implemented to identify the predictors of depression. Data were entered and analyzed using SPSS 22.0 software. Findings The study found the overall prevalence of depression among patients on hemodialysis to be 43.6 per cent. Of them, 12.8 per cent were mildly depressed, 15.6 per cent were moderately depressed and 15.1 per cent fell in the severe or extremely severe category. Depression was significantly associated with marital status, education level and the presence of sleep disturbances. The study indicates a high prevalence of depressive symptoms among patients on hemodialysis in Jazan. A higher rate of depressive symptoms was observed in currently unmarried, lower-educated patients and those with sleep disturbance. Originality/value Periodic evaluation of patients on hemodialysis for depression is needed to allow for early intervention.

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