scholarly journals POSSIBILITY OF ARTERIAL HYPERTENSION DEVELOPMENT IN THE POPULATION OF THE NORTHWEST OF RUSSIA WITH EXCESSIVE BODY WEIGHT AND OBESITY

Author(s):  
Boris Fishman ◽  
Pavel Kuprin ◽  
Michael Fishman ◽  
Alla Chorochevskaja ◽  
Marat Chapman ◽  
...  
Kardiologiia ◽  
2020 ◽  
Vol 60 (10) ◽  
pp. 73-79
Author(s):  
Yu. V. Semenova ◽  
A. B. Karpov ◽  
R. M. Takhauov ◽  
I. V. Milto ◽  
E. I. Shanina ◽  
...  

Aim To study the association between concentrations of endothelial dysfunction (ED) markers and arterial hypertension (AH) in people who were exposed to long-term action of “low-dose” ionizing radiation.Material and methods The study subjects were men of middle age (45–55 years) who were workers of the Siberian Integrated Chemical Plant with the length of service on the shop floor of at least 5 years. The subjects were divided into the main group (n=96) consisting of workers with grade 1-2 AH and the control group (n=48) consisting of arbitrarily healthy workers. Both groups contained workers who had been exposed to long-term occupational low-intensity irradiation (γ-radiation) and those not exposed to this irradiation. The study evaluated risk factors for cardiovascular diseases, presence of concomitant diseases, blood biochemistry (concentrations of glucose, high-sensitivity C-reactive protein (hsCRP), total cholesterol, low-density lipoproteins, high-density lipoproteins, triglycerides, creatinine, and ED markers, including endothelin, angiotensin II, von Willebrand factor, C-type natriuretic peptide, tissue plasminogen activator, tumor necrosis factor α (TNF-α), and homocysteine, major clinical data, total dose of external irradiation, and the content of 239Pu in the body.Results AH was associated primarily with excessive body weight and severity of atherogenic dyslipidemia and homocysteinemia. Higher plasma concentrations of TNF-α and a tendency to increasing hsCRP in the AH group, as distinct from the control group of arbitrarily healthy men, indicated a proinflammatory shift. The ED markers were related with clinical data of AH patients and associated with the lipid profile and increased blood concentrations of inflammatory mediators. The radiation exposure did not change the ED marker array in AH patients, which did not allow recommendation of the studied plasma indexes for detection of vascular endothelial injury in workers with AH of the Siberian Integrated Chemical Plant.Conclusion The study results evidenced the absence of adverse effects of long-term occupational exposure to low-intensity radiation on the vascular endothelium as evaluated by ED markers. In men aged 45–55 years, AH was associated primarily with excessive body weight, homocysteinemia, and atherogenic dyslipidemia.


2015 ◽  
Vol 13 (1) ◽  
pp. 30-35
Author(s):  
Nataliya S. Tsyplenkova ◽  
Elena I. Panova

Aim. To study features of heart rate of men with arterial hypertension and obesity, to identify factors associated with arrhythmia evolution.Materials and methods. The study included 3 groups of men (with obesity – 98 men, with excessive body weight – 46 men, with normal body weight – 40 men). The comparative analysis of heart rhythm was performed with Resting ECG and Holter ECG monitoring, blood pressure from daily monitoring, echocardiography, blood lipid spectrum, glycaemia. The adiponectin level was analyzed only for group with obesity.Results. Obesity in men with arterial hypertension increases the frequency of arrhythmias of atrial fibrillation (AF) type (15.3% vs. 0% in group with normal body weight, p=0.004) and increases the frequency of ventricular premature beats (VPB) (26.5% in group with obesity vs. 10% in group with normal body weight). We were also able to show the relation between arrhythmia and the severity of obesity. Obesity with arterial hypertension significantly increases the risk of various arrhythmias (more than 6 times for AF risk – p=0.004 and more than 5.31 times for frequent VPB – p=0.026. Risk factors for AF are statistically significant with the presence of obesity: left ventricular (LV) and left atrium (LA) dilation, II–III stage of hypertension and low level of high-density lipoprotein (p0.05). AF risk factors are significant without relation to obesity: left ventricular hypertrophy, dilatation LA, IHD (p0.05). But there is no relation between ischemic heart disease (IHD) and an increased risk of AF evolution. Also no relation was found between sleep apnea syndrome and arrhythmias.Conclusion. Men with excessive body weight or obesity in contrast to men with normal body weight have an increased risk of AF and VPB. Factors directly associated with arrhythmias: heart remodeling (hypertrophy and dilatation of the left ventricular, dilatation of the left atrium), advanced stages of arterial hypertension, dyslipidemia; IHD with obesity associated with risk of VPB and doesn’t affect the AF frequency. 


2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Albane BR Maggio ◽  
Xavier E Martin ◽  
Catherine Saunders Gasser ◽  
Claudine Gal-Duding ◽  
Maurice Beghetti ◽  
...  

2018 ◽  
Vol 20 (3) ◽  
pp. 250-254
Author(s):  
Agnieszka Pawelak ◽  
Maciej Ornat ◽  
Krzysztof Pachołek ◽  
Agnieszka Wróblewska ◽  
Bartosz Jerczak ◽  
...  

ScienceRise ◽  
2016 ◽  
Vol 2 (3 (19)) ◽  
pp. 44
Author(s):  
Тетяна Олександрівна Ілащук ◽  
Наталія Валентинівна Швець ◽  
Оксана Павлівна Микитюк

2020 ◽  
Vol 4 (1-3) ◽  
pp. 45
Author(s):  
Dania Mirza Ramadhanty ◽  
Bernie Endyarni Medise

Objective. Overweight is one of the health problems that often occur in children and adolescents throughout the world, both in developed and developing countries. Study results in USA showed yearly increase of overweight prevalence in children aged 2–19 years old. In addition, based on the results by the National Health and Nutrition Examination Survey 2009–2010 in United States, the highest percentage of overweight and obesity by age group was found at 12–19 years old (33.6%). Basic Health Research/Riskesdas’s data in 2013 showed the prevalence of overweight in adolescents aged 16–18 years old in Indonesia reached the highest value of 11.5%. Moreover, most teenagers see their body images as a match between self’s and others’ ideal perception. Teenagers with positive body image tend to be more confident and also easier to get along with other people, especially their peers. In this study, researcher aimed to investigate the relationship between teenagers who have excess body weight with body image, whether it had positive or negative impact.Methods: This was a cross-sectional study. Data collection was done from December 2017 to January 2018. Data collected were anthropometric measurements (weight and height) and the King College London Body Image Questionnaire's filled by participants. From 400 subjects who filled the questionnaires, a total of 350 participants matched the inclusion criteria and were analyzed. Chi square test was done as data analysis.Results: Chi-square analysis for excess body weight status in relation to body image scores showed no relationship (p=1,000).Conclusions: There was no significant relationship between excessive body weight and body image. 


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