Medication overuse headache : The effectivity of IV lidocaine – magnesium

2021 ◽  
Vol 74 (9-10) ◽  
pp. 323-328
Author(s):  
Nermin Tepe ◽  
Oktay Faysal Tertemiz

The detoxification process in medication overuse headache is the most difficult process for the patient. We aimed to investigate the effectiveness of the combination of low dose IV lidocaine and magnesium (100 mg lidocaine and 1.25 mg magnesium) in patients with medication overuse headache during the detoxification process. A total of 30 patients were included in the study; 15 received 24 hours of IV hydration, 15 received 1-hour lidocaine-magnesium infusion at the onset of pain in addition to the 24 hours of IV hydration. Headache severity (numeric rating scale, NRS), attack durations, onset of headache, monthly analgesic/triptan intakes, numbers of monthly headache days data were documented. We evaluated the severity of headache before and after daily treatment of two groups for one week. When both groups were compared, there was no significant difference in the pre-treatment NRS values, whe­reas, in the group receiving IV lidocaine-magnesium combination, there was a statistically significant decrease in the post-treatment NRS values in the first five days (p <0.05). An 1-hour combined infusion of lidocaine-magnesium may be considered as an alternative option for the patient to have a more quality detoxification process during the hospital stay, so that in parallel to the reduction in the use of multiple treatments (such as neuroleptics, benzodiazepines, antiemetics and opioids) and duration length of stay, the economic costs can also be reduced. The administration of combination will bring fewer side effects compared to their administration separately.

Author(s):  
Lutfatul Latifah ◽  
Dian Ramawati

Introduction: Every woman who undergo Sectio Caesaria (SC) surgery for delivery their babies often complain about pain after the surgery and it become very distrubing. The effect of the pain cause mobilisation limitation, interrupting bonding attachment between mother and child, and postponning breastfeeding inititation. This study conduct EFT or tapping as the pain management in women post SC surgery.The aim of this study is to identify the effect of EFT or tapping for reducing pain after SC surgery. Methods: Quasy experimental with pre-post non randomized control group design was used in this study. The data been colleted using Numeric Rating Scale (NRS) to measure the pain in participants before and after EFT or tapping treatment. The number of participants was 30 mothers with 15 women in control and treatment group respectively. The t-test was used to analize the effect of the EFT. Results: The mean of pain scale before treatment in control group was 5.20 dan 6.20 for the treatment group. The pain scale after treatment in control group was 5.00 and 4.27 in treatment group. There was a significant difference between the reducing pain scale in treatment group with p value = 0,000 (α = 0.05). Discussion: EFT or tapping can be one of many non farmacologic treatment as complementer therapy to reduce pain after SC surgery. Keywords: post SC pain, EFT, pain scale decline, non farmacologic therapy


2021 ◽  
Vol 3 (1) ◽  
pp. 25-30
Author(s):  
Ayu Safitri ◽  
Artika Dewie ◽  
Niluh Nita Silvia

Introduction: Pharmacological and non-pharmacological techniques are methods used to reduce labor pain. Non-pharmacological techniques in the form of distraction by listening to the murottal Al-Qur'an can be an option. The purpose of this study was to determine the effect of murottal Al-Qur'an therapy on reducing the intensity of labor pain during the 1st active phase. Method: The type of research used in this study was Pre Experiment, one group pretest-posttest research design. The population in this study were mothers who gave birth at the first stage of Sriwati PMB with a sample of 15 people. The pain was measured using the Numeric Rating Scale (NRS). Statistical analysis used the Wilcoxon Signed Rank Test with a confidence level of 95% (α = 0.05). The result of the statistical test, the value of p=0.001, which means that there is a significant difference in labor pain in women who give birth before and after listening to the Murottal Al-Qur'an. It is suggested to do non-pharmacological techniques to listen to Murottal Al-Qur'an as one of the techniques to reduce the first stage labor pain at PMB Sriwati.


2020 ◽  
Vol 9 (2) ◽  
pp. 580-587
Author(s):  
Shinta Novelia ◽  
Milla Evelianti Saputri ◽  
Ficky Adi Putri Sinkawati

Pain is the most common adverse effects in the early postoperative period. Routine pharmacologic Methods may impair the recovery of patients for their sedative and emetic effects. Therefore, patients’ relaxation is necessary for a successful post-operative pain managements and it is among the interventions addressed to improve physiologic response. The aim of this study was to examine the effects of zikr meditation on post-operative pain among post cesarean section women. This is a quasy experimental research with control group pre-test post-test. A total of 30 muslim post cesarean section women were included in the study.  Medical information form, Numeric Rating Scale, and Interument Guideline are used to collect the data. The results show that there is a significant difference of pain between experiment and control group (p= .012), there is a significant difference of pain before and after intervention in the experiment group (p=  .00).


2020 ◽  
Vol 13 (2) ◽  
pp. 104
Author(s):  
Andi Adriana Amal ◽  
Hasnah Hasnah ◽  
Nur Rezki Hadiyanti Z

Dysmenorrhoea is experienced by most girls which causes them to be absent from school repeatedly so that proper management of dysmenorrhea is needed. This study aims to determine the effectiveness of murottal therapy and finger handheld relaxation in adolescents with dysmenorrhea. This research method is a quantitative research with a quasi experiment with control group, the study population is young women with dysmenorrhea and the sample consists of 36 girls with dysmenorrhea divided into 18 respondents in the murottal therapy group and 18 respondents in the finger handheld relaxation group. The dysmenorrhea pain scale was measured by the Numeric Rating Scale (NRS). The results showed that there were significant differences before and after the intervention, both murottal therapy and finger handheld relaxation with p value <0.0001. There was no significant difference in the murottal therapy and finger handheld relaxation groups with p value = 0.486. From the results of the study, it was concluded that murottal therapy and finger handheld relaxation were effective against dysmenorrhea in adolescents so that these two interventions could be used to treat dysmenorrhea in young womenABSTRAKDismenorea dialami sebagian besar remaja perempuan yang menyebabkan ketidakhadiran mereka di sekolah secara berulang sehingga dibutuhkan manajemen dismenore yang tepat. Penelitian ini bertujuan untuk mengetahui bagaimana efektivitas murottal theraphy dan fing er handheld relaxation pada remaja dengan dismenore. Metode penelitian ini adalah penelitian kuantitatif dengan quasi eksperiment with control group, populasi penelitian adalah remaja putri dengan dismenore dan sampel terdiri dari 36 remaja putri dengan dismenore yang dibagi menjadi 18 responden pada kelompok murottal theraphy dan 18 responden pada kelompok finger handheld relaxation. Skala nyeri dismenore diukur dengan Numeric Rating Scale (NRS). Hasil penelitian menunjukkan terdapat perbedaan yang bermakna sebelum dan setelah diberikan intervensi baik murottal therapy maupun finger handheld relaxation dengan nilai p <0.0001. Tidak ada perbedaan signifikan pada kelompok murottal therapy dan finger handheld relaxation dengan nilai p=0,486. Dari hasil penelitian disimpulkan bahwa murottal therapy maupun finger handheld relaxation efektif terhadap dismenore pada remaja sehingga kedua intervensi ini dapat digunakan dalam mengatasi dismenore pada remaja putri 


2020 ◽  
Vol 2 (1) ◽  
pp. 30-34
Author(s):  
Ummara Qadeer ◽  
Anan Aftab ◽  
Iman Zahra

Objective: To compare whether heat therapy (moist heat pack) is more effective before exercise therapy or after exercise therapy in chronic MSK pain in females. Design Randomized clinical trial study. Methodology: This study is conducted in Abbas institute of medical sciences Muzaffarabad and Muzaffarabad physiotherapy clinic Muzaffarabad.40 female patients with chronic MSK pain are recruited in the study and a questionnaire-based survey was carried out. A self-structured questionnaire is used for demographic details. For screening of chronic MSK pain short form of Orebro pain questionnaire is used. A numeric rating scale in both groups is used to check the intensity of pain. Result: The results showed that between group A and B there was no significant difference. But clinically group B showed more improvement than group A.Both groups showed improvement after treatment. Conclusion: The application of heat therapy (moist hot pack) was found to be more effective after exercises than its use before exercises to improve pain in females with chronic musculoskeletal pain.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Maxime Fieux ◽  
Antoine Gavoille ◽  
Fabien Subtil ◽  
Sophie Bartier ◽  
Stéphane Tringali

Abstract Background The ongoing COVID-19 pandemic has disrupted the surgical training of residents. There is a real concern that trainees will not be able to meet their training requirements. Low-fidelity surgical simulation appears to be an alternative for surgical training. The educational benefits of repeating ossiculoplasty simulations under a microscope have never been evaluated. With this study we aimed to evaluate the differences in performance scores and on a global rating scale before and after training on an ossiculoplasty simulator. Methods In this quasi-experimental, prospective, single-centre, before-after study with blinded rater evaluation, residents performed five microscopic ossiculoplasty tasks with a difficulty gradient (sliding beads onto rods, the insertion of a partial prosthesis, the insertion of a total prosthesis, and the insertion of a stapedotomy piston under microscopic or endoscopic surgery) before and after training on the same simulator. Performance scores were defined for each task, and total performance scores (score/min) were calculated. All data were collected prospectively. Results Six out of seven intermediate residents and 8/9 novices strongly agreed that the simulator was an effective training device and should be included in the ENT residency program. The mean effect of training was a significant increase in the total performance score (+ 0.52 points/min, [95 % CI, 0.40–0.64], p < 0.001), without a significant difference between novice and intermediate residents. Conclusions This preliminary study shows that techniques for middle-ear surgery can be acquired using a simulator, avoiding any risk for patients, even under lockdown measures.


Cephalalgia ◽  
2006 ◽  
Vol 26 (10) ◽  
pp. 1192-1198 ◽  
Author(s):  
P Zeeberg ◽  
J Olesen ◽  
R Jensen

It is generally accepted that ongoing medication overuse nullifies the effect of prophylactic treatment, although few data support this contention. We set out to describe the treatment outcome in patients withdrawn from medication overuse and relate any improvement to a renewed effect of prophylaxis. For patients with probable medication-overuse headache (pMOH), treated and dismissed from the Danish Headache Centre in 2002 and 2003, we assed, from prospective headache diaries, the headache frequency before and after withdrawal of offending drugs and compared these frequencies with the headache frequency at dismissal. Among 1326 patients, 337 had pMOH. Eligible were 175, mean age 49 years, male/female ratio 1: 2.7. Overall, there was a 46% decrease in headache frequency from the first visit to dismissal ( P < 0.0001). Patients with no improvement 2 months after complete drug withdrawal ( N = 88) subsequently responded to pharmacological and/or non-pharmacological prophylaxis with a 26% decrease in headache frequency as measured from the end of withdrawal to dismissal ( P < 0.0001). At dismissal, 47% were on prophylaxis. Former non-responders to medical prophylaxis had a 49% decrease in headache frequency from first visit to dismissal ( P < 0.0001), whereas those who had never received prophylaxis had a 56% reduction ( P < 0.0001). This difference was not statistically significant ( P = 0.22). Almost all MOH patients benefit from drug withdrawal, either just from the withdrawal or by transformation from therapeutic non-responsiveness to responsiveness. According to the International Classification of Headache Disorders, 2nd edn, the MOH diagnosis requires improvement after drug withdrawal. Our data suggest that these diagnostic criteria are too strict.


Author(s):  
Kun Yung Kim ◽  
Gi-Wook Kim

BACKGROUND: Knee osteoarthritis (OA) is accompanied by inflammation and angiogenesis. Modifying angiogenesis through transcatheter arterial embolization (TAE) can be a potential treatment for knee OA. OBJECTIVE: We subjected five OA knees in three patients to TAE and report the results of our post-treatment observations. CASE DESCRIPTION: Three patients that had experienced knee pain for a minimum of one year prior to the study, and whose pain had persisted despite conservative treatment, were included in this study. Patients more often chose conservative treatment over surgical treatment. Pain and functional scales were evaluated before, immediately, and 1 month after TAE using the Numeric Rating Scale (NRS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). TAE was performed by an experienced interventional radiologist. The average values of NRS evaluated before and after 5 TAEs were 5.2 before TAE, 3 immediately after TAE, and 3.6 after 1 month of TAE, and the average values of WOMAC were 52, 38.4, and 36.4, respectively. There were no major adverse effects. CONCLUSION: The examined cases support the conclusion that TAE is an effective treatment for patients with knee OA. Substantial pain relief and WOMAC improvement were observed both immediately and one month after TAE.


2021 ◽  

Background: Treatment provided in an emergency department is aimed at alleviating pain immediately with minimized adverse effects as well as warding off further migraine attacks. The primary aim of this article is to compare the effectiveness of oral paracetamol versus zolmitriptan in treating acute migraine attacks. Methods: This prospective, randomized, and controlled study was carried out at a tertiary care hospital visited by 95,000 patients annually. The study recruited 200 participants who were randomized into two groups. One group received 1000 mg paracetamol while the other group received 2.5 mg zolmitriptan orally. Baseline pain scores were recorded using the Visual Analogue Scale (VAS) and Numeric Rating Scale (NRS) at 15, 30 and at 60 min following administration of the study drugs. Patients requiring further treatment were provided fentanyl at a dosage of 1 µg/kg as a rescue therapy. Results: A significant decrease was evident in VAS and NRS scores following the administration of the study drugs in both groups (P < 0.001). The change in VAS pain scores after 15, 30 and 60 min was calculated as 17.0 ± 13.9, 41.2 ± 16.3 and 61.2 ± 17.5 mm, respectively, in the paracetamol group and 14.2 ± 11.7, 39.2 ± 17.9 and 59.2± 19.3 mm, respectively, in the zolmitriptan group, which did not indicate significant differences (P = 0.103, P = 0.425, P = 0.483, respectively). Likewise, NRS pain scores showed a downward trend in line with VAS pain scores and did not yield a significant difference (P = 0.422). No significant difference concerning rescue therapy was noted between the two groups (P = 0.596). Conclusion: Oral paracetamol and zolmitriptan prove to be similarly effective and have low incidence of acute side effects in treating acute migraine cases without aura.


2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Afshin Farhanchi ◽  
Behrouz Karkhanei ◽  
Negar Amani ◽  
Mashhood Aghajanloo ◽  
Elham Khanlarzadeh ◽  
...  

Introduction. In this study we are aiming to evaluate the changes of serum serotonin and its association with pain in patients suffering from chronic low back pain before and after lumbar discectomy surgery. Patients and Methods. A prospective study was performed on the patients referring to the outpatient clinic in Besat hospital, Hamadan University of Medical Sciences, Hamadan, Iran, during 2016. A 2 mL fasting blood sample was collected from each patient at preoperative day 1 and postoperative day 14 and they were measured for level of serum serotonin. Besides, all patients were asked for severity of their low back pain in preoperative day 1 and postoperative day 14 and scored their pain from zero to ten using a Numerical Rating Scale. Results. Forty patients with the mean age of 47 ± 13 yrs/old (range 25–77) including 15 (37.5%) males were enrolled into the study. The overall mean score of preoperative pain was significantly decreased from 7.4 ± 2.18 (range 4–10) to the postoperative pain score 3.87 ± 2.92 (range 0–10) (P < .001). The overall levels of pre- and postoperative serum serotonin were 3.37 ± 1.27 (range 1.1–6.4) and 3.58 ± 1.32 (range .94–7.1) ng/mL, respectively, with no significant difference (P = .09). The levels of pre- and postoperative serum serotonin were significantly higher in males and patients older than 50 yrs/old compared to the females and patients younger than 50 yrs/old, respectively (P = .03 and .005, respectively). A significant inverse correlation between the postoperative levels of pain and serum serotonin was observed (r = -.36 and P = .02). Conclusion. A negative medium strength linear relationship may exist between the postoperative serum serotonin and low back pain.


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