scholarly journals A study of drug utilization pattern and pharmacoeconomic of antidiabetic drugs in patients attending a teaching hospital

2018 ◽  
Vol 7 (4) ◽  
pp. 796
Author(s):  
Shanthi M.
Keyword(s):  
Diabetes Mellitus ◽  
Drug Utilization ◽  
Pharmacoeconomic Analysis ◽  
Current Trend ◽  
Cross Sectional Study ◽  
Antidiabetic Drugs ◽  
Systemic Hypertension ◽  
Cross Sectional ◽  
Female Population ◽  
One Year

Background: Drug utilization research establishes the current trend in the use of antidiabetic drugs including the new drug and to identify irrational prescription.Methods: A cross-sectional study was conducted for a period of one year (between August 2013 to August 2014) at outpatient department of Medicine, Sree Mookambika Institute of Medical Sciences, Kulasekharam, Kanyakumari District, Tamil Nadu.Results: A total of 169 prescriptions were evaluated during the study period. Diabetes mellitus was predominant among the female population in this region. Demographic details of the patient included in the study were mean weight 67.56kg, mean height 155cm and average body mass index 27.82kg/m2. All the patients were diagnosed and were known case of type 2 diabetes mellitus. Systemic hypertension was the frequently encountered co-morbid conditions associated with this endocrine disorder. Metformin was the drug chosen for managing diabetes as monotherapy and 73% of the patients were on combination of antidiabetic drugs. Glimepiride with metformin was the combination therapy frequently prescribed during the study period. Pharmacoeconomic analysis identified that drugs prescribed by brand name were costlier compared to generic equivalent.Conclusions: Utilization of antidiabetic drug therapy in this region has shown a changing trend compared to the previous studies. There is a gradual increase in the prescription of metformin and dramatic increase in the use of newer drugs like pioglitazone, voglibose and sitagliptin. Pharmaeconomic analysis revealed that glibenclamide was least expensive while sitagliptin was most expensive in this study.

scholarly journals Cost-effectiveness study of antidiabetic drugs in type 2 diabetes mellitus patients from Mumbai, India

2017 ◽  
Vol 4 (9) ◽  
pp. 3180 ◽  
Author(s):  
Dnyanesh Limaye ◽  
Krishna Todi ◽  
Jay Shroff ◽  
Ashutosh Ramaswamy ◽  
Priyanka Kulkarni ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Cost Effectiveness ◽  
Cross Sectional Study ◽  
Antidiabetic Drugs ◽  
Cross Sectional ◽  
Validated Questionnaire ◽  
The Cost

Background: Diabetes is fast gaining the status of a potential epidemic in India, with >62 million individuals currently diagnosed with the disease. India currently faces an uncertain future in relation to the potential burden that diabetes may impose on the country. An estimated US$ 2.2 billion would be needed to sufficiently treat all cases of type 2 diabetes mellitus (T2DM) in India. Many interventions can reduce the burden of this disease. However, health care resources are limited; thus, interventions for diabetes treatment should be prioritized. The present study assesses the cost-effectiveness of antidiabetic drugs in patients with T2DM from Mumbai, India.Methods: A prospective cross-sectional study was performed to assess the cost-effectiveness of antidiabetic drugs in patients with T2DM. Face-to-face interviews were conducted by using a validated questionnaire in a total of 152 (76 males, 76 females) patients with T2DM from F-North Ward, Mumbai, India. Cost-effectiveness was determined on the basis of cost of antidiabetic drug/s, efficacy, adverse drug reactions, safety of administration, frequency of administration, and bioavailability. Results: For treatment of T2DM in non-obese participants, Glimepiride+Pioglitazone costed least (`3.7) per unit of effectiveness followed by Glimepiride (`6.6), Gliclazide (`8.1), Repaglinide (`24.5), and Vildagliptin (`45.2). For treatment of T2DM in obese participants, Metformin cost least (` 6.7) per unit of effectiveness followed by Glimepiride + Metformin (`5.9) and Repaglinide (`24.5). Conclusions: In case of non-obese participants, cost effectiveness and prescribed treatments did not show a match, while for obese participants prescribed treatments were in line with cost effectiveness. 

scholarly journals Erectile dysfunction in patients of diabetes mellitus: a cross sectional study

2019 ◽  
Vol 6 (8) ◽  
pp. 2941
Author(s):  
Anilkumar Bellad ◽  
Kartik Sahu
Keyword(s):  
Diabetes Mellitus ◽  
Erectile Dysfunction ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Duration Of Diabetes ◽  
Mild Degree ◽  
Patients With Diabetes ◽  
History Of ◽  
One Year

Background: One of the independent risk factor for erectile dysfunction is diabetes mellitus. The present study planned to determine the prevalence and factors associated with ED in DM.Methods: A one year cross-sectional study on a total of 208 patients with type 1 or 2 diabetes. National Institutes of Health (NIH) approved questionnaire for International Index of Erectile Function (IIEF) was used to interview each patient to assess for ED.Results: In this study 12.98% of patients had ED score between 13 to 18 suggestive of mild to moderate ED and 9.62% with 19 to 24 scores suggestive of mild degree. The prevalence of erectile dysfunction was 32.21%. The mean age in patients with erectile dysfunction was significantly high (58.40±10.96 years) compared to those without erectile dysfunction (51.00±11.16 years) (p<0.001) Of the 119 patients with duration of diabetes between one to five years 42.02% had ED and of the 3 patients with duration of more than five years 66.67% had ED (p<0.001). Prevalence of ED was higher in patients with HbA1c levels between 7.0 to 8.5 (32.76%) and >8.5 (37.07%). Prevalence of erectile dysfunction was higher in patients with history of smoking (63.64%) (p<0.001) and alcohol intake (51.85%) (p<0.001). The prevalence of erectile dysfunction was also significantly high in patients with history of hypertension (59.7%) (p<0.001).Conclusions: The ED in patients with diabetes mellitus was significantly prevalent with age, duration of diabetes, history of hypertension, cardiovascular disease, glycemic control and hypertriglyceridemia.

scholarly journals RESILIENCE AND SELF-CARE IN PEOPLE WITH DIABETES MELLITUS

2020 ◽  
Vol 29 ◽  
Author(s):  
Julia Estela Willrich Boell ◽  
Denise Maria Guerreiro Vieira da Silva ◽  
Maria Elena Echevarria Guanilo ◽  
Kathleen Hegadoren ◽  
Betina Hörner Schlindwein Meirelles ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Statistical Significance ◽  
Glucose Monitoring ◽  
Self Care ◽  
Cross Sectional Study ◽  
Blood Glucose Monitoring ◽  
Foot Care ◽  
Cross Sectional ◽  
Resilience Scale ◽  
One Year

ABSTRACT Objective: to investigate the association between resilience and self-care in people with diabetes mellitus treated in Primary Health Care. Method: Cross-sectional study, sample consisting of 362 people, aged 18 years or older, diagnosed with diabetes for at least one year. Descriptive analyzes and comparison of means were performed, assuming statistical significance with a value of p <0.05. The Resilience Scale and Questionnaire on Diabetes Self-Care Activities were applied, containing six dimensions: general food, specific food, physical activity, blood glucose monitoring, foot care, medication use, plus three items on smoking. Data collection took place between December and May 2016, in ten Health Centers in a city in the south of the country. Results: among the 15 self-care activities, four showed a statistically significant association when compared to the average resilience, highlighting: healthy eating and professional guidance, desirable sweet consumption, blood sugar assessment as recommended. Conclusion: the results obtained highlight the relationship between high averages of resilience and adequate performance in the care of diabetes mellitus.

scholarly journals Prevalence of metabolic syndrome in a rural population- a cross sectional study from Western Uttar Pradesh, India

2017 ◽  
Vol 5 (5) ◽  
pp. 2223 ◽  
Author(s):  
Khwaja S. Zafar ◽  
Tony Pious ◽  
Prem S. Singh ◽  
Rajesh K. Gautam ◽  
Sudhir K. Yadav ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Metabolic Syndrome ◽  
Rural Population ◽  
Dietary Habits ◽  
Uttar Pradesh ◽  
Cross Sectional Study ◽  
Current Status ◽  
Cross Sectional ◽  
Female Population ◽  
The Metabolic Syndrome

Background: Prevalence of non-communicable diseases like hypertension, diabetes mellitus and coronary artery disease is on the rise due to the change in lifestyle, unfavourable dietary habits and obesity. Metabolic syndrome is a simple tool by which we can predict the future risk of diabetes mellitus and cardiovascular disease. Studies showed that prevalence of metabolic syndrome is rising in Indian population, but majority of them were done in urban population. This study was conducted to look into the current status of the metabolic syndrome in rural population.Methods: The study was conducted among a population of 2982. Each participant was subjected to clinical examination, anthropometric measurements and necessary laboratory investigations. Metabolic syndrome was diagnosed based on modified NCEP: ATP III criteria.Results: The prevalence of metabolic syndrome was found to be 11.7% and was higher among female population (13.8%) as compared to males (9.6%). The prevalence of metabolic syndrome increased with increasing age. 28.3% of the participants over the age of 50 years had metabolic syndrome whereas it was only 0.4% below the age of 20 years. Nearly half (47.1%) of the obese individuals were suffering from metabolic syndrome implicating obesity as one of the most important risk factors in the etiopathogenesis of metabolic syndrome. The prevalence was only 1.1% among the underweight group.Conclusions: Present study has shown moderate prevalence of metabolic syndrome among the rural population of Western Uttar Pradesh, India with a more female predisposition.

scholarly journals Prescribing pattern and pharmacoeconomic analysis of antidiabetic drugs

2019 ◽  
Vol 8 (8) ◽  
pp. 1844
Author(s):  
Pardeep Kumar Goyal ◽  
Shalini Arora ◽  
Naveen Mittal ◽  
Bharti Mahajan ◽  
Sandeep Kaushal
Keyword(s):  
Drug Therapy ◽  
Pharmacoeconomic Analysis ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Antidiabetic Drugs ◽  
Care Hospital ◽  
Prescribing Pattern ◽  
Cross Sectional ◽  
Number Of Patients ◽  
Dual Drug

Background: Diabetes Mellitus is a worldwide growing problem causing threat to patient's health because of its association with various complications and comorbidities. It is a chronic disease requiring lifelong medication which further adds to the economic burden. The objective of this study was to evaluate the prescribing pattern and to do pharmacoeconomic analysis of prescribed antidiabetic drugs.Methods: This observational cross sectional study was conducted for 12 months duration in Outpatient Pharmacy of tertiary care hospital. Prescriptions with antidiabetic drugs were captured and evaluation of prescribing pattern along with pharmacoeconomic analysis of antidiabetic drugs was done.Results: A total of 611 prescriptions with antidiabetic drugs were analyzed. There were total 4034 drugs in all prescriptions with a mean of 6.6 drugs per prescription. 4.28% of drugs were prescribed by generic name and 58.9% of prescribed drugs were from essential drug list. Dual drug therapy was prescribed in maximum number of patients (42.2%) followed by monotherapy (28.8%). More commonly prescribed class of antidiabetic drugs was biguanides as monotherapy (n=119) and its combination with sulfonylureas was prescribed maximally among dual drug therapy (n=158). Cost of monthly therapy for antidiabetic drugs prescribed as monotherapy was least with Biguanides (₹ 98.89/ month) whereas combination of biguanides and thiazolidinediones was least expensive among dual drug therapy (₹ 216/ month).Conclusions: Biguanides was the most common prescribed class of antidiabetic drugs among monotherapy and its combination with sulfonylureas was most prescribed as dual drug therapy and both of these therapies were economical.

scholarly journals Tuberculosis and diabetes mellitus: sociodemographic and clinical profile in Brazilian municipalities

2021 ◽  
Vol 42 ◽  
Author(s):  
Aline Ale Beraldo ◽  
Rubia Laine de Paula Andrade ◽  
Érika Simone Galvão Pinto ◽  
Reinaldo Antônio da Silva-Sobrinho ◽  
Nanci Michele Saita ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Treatment Time ◽  
Multiple Correspondence Analysis ◽  
Descriptive Analysis ◽  
Cross Sectional Study ◽  
Clinical Profile ◽  
Cross Sectional ◽  
Female Population ◽  
Analysis Techniques ◽  
Secondary Sources

ABSTRACT Objective To analyze the sociodemographic and clinical profile of tuberculosis cases with Diabetes Mellitus in Brazilian municipalities in the states of São Paulo, Paraná and Rio Grande do Norte. Method This is a cross-sectional study, whose population consisted of tuberculosis cases notified between 2010 and 2014. Data were collected from secondary sources. In the data analysis, descriptive analysis and multiple correspondence analysis techniques were used. Results The prevalence of diabetes among tuberculosis cases ranged from 4.5% to 13.4% in the municipalities. Evidence of an association was observed between tuberculosis/diabetes comorbidity and female population, age of 61 years or more, low schooling, negative HIV/AIDS, longer treatment time, self-administered treatment and cure. Conclusion The study showed a greater cure outcome in the profile of people with tuberculosis/diabetes comorbidity, even among those on a self-administered regime, which could favor the development of specific guidelines for the management of tuberculosis in these people.

scholarly journals Frequency of fear of fall among diabetic patients in Hayatabad Medical Complex Peshawar

2020 ◽  
Vol 2 (1) ◽  
pp. 14-18
Author(s):  
Adnan Khan ◽  
Tajamul Ahmad ◽  
Nadia Afridi ◽  
Madiha Anees ◽  
Bilal Khan
Keyword(s):  
Diabetes Mellitus ◽  
Sampling Technique ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Cross Sectional ◽  
Female Population ◽  
Major Health ◽  
Patients With Diabetes ◽  
History Of ◽  
Major Health Issue

Introduction: A fall may be defined as a loss of balance, resulting in coming to rest on the ground or on another object below knee level. Fear of all or Basophobia is a condition of concern towards falls and natural fear of unable to stand or walk. Since the identification of the post-fall syndrome, fear of fall is considered the major health issue among elderly population. Therefore, this study was conducted to measure the level of fear of fall and factors which might contribute to it. Material & Methods: It was a cross sectional study conducted to measure the level of fear of fall among the diabetic patients of Hayatabad Medical Complex Peshawar. According to the inclusion criteria, participants who had age more than 40 years and diabetic history of more than 2 years were included in the study. We measured the fear of fall with age, gender and duration of diabetes mellitus. Convenient sampling technique was used for the recruitment of the participants. Data was collected by self-repored questionnaires and was analyzed by SPSS 20.0 version. Results: A total of 306 participants, 164 (53.59%) males and 142 (46.40%) female with a mean age 56.02 ± 9.68 years (mean ± sd) were recruited. The level of fear of all was high in diabetic patients in which 222 (72.5%) participants showed high, 48 (15.7%) moderate and 36 (11.8%) low concerns. Conclusion: Fear of fall is a common problem in both male and female population having diabetes mellitus. It is one of the major concerns among patients with diabetes. It has a positive relation with age, duration of DM, and insulin intake.

scholarly journals Study of serum magnesium levels in diabetes mellitus and its correlation with complications (retinopathy and HbA1c) a cross-sectional study of one year

2017 ◽  
Vol 4 (1) ◽  
pp. 263
Author(s):  
Nipun Saproo ◽  
Roma Singh
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Serum Magnesium ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Chronic Hyperglycemia ◽  
One Year

Background: Diabetes mellitus is a heterogeneous group of metabolic disorders characterized by chronic hyperglycemia with disturbance of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both. The aim of this study was to estimate serum magnesium levels in patients with type 2 diabetes mellitus and correlate it with complications of type 2 diabetes mellitus - glycemic control and retinopathy.Methods: A cross-sectional study of 100 patients with type 2 diabetes, attending Government Medical College and associated Hospital, Jammu over a period of one year from 1st November, 2014 to 30th October, 2015. Detailed history including duration of diabetes, treatment mode, symptoms suggestive of retinopathy and associated diseases such as hypertension and ischemic heart disease were obtained, as per the proforma, followed by physical examination.Results: Majority of patients (38%) of type-2 diabetes mellitus were in the age group of 51-60 years. Males constituting 71% with male to female ratio of 2.45:1. Complications were observed in 48 cases, which mainly included retinopathy 60.42% (all non-proliferative). Maximum patients (79%) had abnormal (>6.5%) glycosylated hemoglobin levels ranging from 6.5 to 12%. Patients with diabetic retinopathy had significantly higher prevalence of hypomagnesaemia compared to patients without retinopathy (58.62 % vs 18.31%).Conclusions: Prevalence of hypomagnesaemia in type 2 diabetes was 30% in the present study. The present study illustrates that as the magnesium level decreases in type 2 diabetes mellitus patients, prevalence of retinopathy increases.

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