scholarly journals A comparative study of intravenous hydration and amnioinfusion for IUGR associated with oligohydramnios in pregnant women and fetomaternal outcome

Author(s):  
Garima Kumari

Background: Ultrasound assessment of amniotic fluid has significant implication in obstetric care and it has become an integral and important component of pregnancy assessment.Methods: A prospective study done in all pregnant women (n=30) who had been diagnosed with oligohydromnios (with AFI<8 by Phelan’s method) by ultrasonography will be attending in obstetric gynecology department SMS Medical College, Jaipur will be selected according to inclusion or exclusion criteria (as per sample size) after written informed consent.Results: Higher incidence of preterm delivery in the i.v. infusion group as compared to the amino acid group and difference was significant (p value <0.05). In amnioinfusion group 3 cases (20.0%) had LSCS and in i.v. infusion group 6 cases (40.0%) had delivered by LSCS. The distribution of delivery mode did not differ significantly across two intervention groups (p value >0.05). Significantly higher proportion of cases from amino acid group had larger birth weight and significantly higher proportion of cases from i.v. infusion group had smaller birth weight (p value <0.001).Conclusions: This study points towards the use of intravenous hydration and amnioinfusion in increasing the liquor in oligohydramnios associated with IUGR and proves useful in reducing perinatal morbidity and mortality.

2019 ◽  
Vol 15 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Harpriya Kaur ◽  
Delf Schmidt-Grimminger ◽  
Baojiang Chen ◽  
K.M. Monirul Islam ◽  
Steven W. Remmenga ◽  
...  

Background: Pregnancy may increase the risk of Human Papillomavirus (HPV) infection because of pregnancy induced immune suppression. The objective of this study was to use a large population-based dataset to estimate the prevalence of HPV infection and its association with adverse outcomes among pregnant women. Methods: We analyzed Pregnancy Risk Monitoring System data from 2004-2011 (N=26,085) to estimate the self-reported HPV infection. Survey logistic procedures were used to examine the relationship between HPV infection and adverse perinatal outcomes. Results: Approximately 1.4% of women were estimated to have HPV infection during their pregnancy. The prevalence of adverse outcomes in this sample was preterm birth (8.4%), preeclampsia (7.5%), low birth weight (6.3%) and premature rupture of membranes (2.8%). Compared to women without HPV infection, HPV infection positive women were much more likely to have had other infections such as chlamydia (9.23% vs. 2.12%, p-value <.0001), Group B Strep (21.7% vs. 10.04%, p-value <.0001), and herpes (7.17% vs. 1.07%, p-value <.0001). After adjusting for other risk factors including other infections, HPV infection was significantly associated with low birth weight (OR: 1.94, 95% CI: 1.14-3.30). Conclusion: The study indicated a potential association between HPV infection and low birth weight. Because pregnant women with HPV infection are at higher risk of other infections, future research may focus on the roles of co-infection in the development of adverse perinatal effects.


2021 ◽  
Vol 10 (4) ◽  
pp. 695 ◽  
Author(s):  
David Ramiro-Cortijo ◽  
María de la Calle ◽  
Andrea Gila-Díaz ◽  
Bernardo Moreno-Jiménez ◽  
Maria A. Martin-Cabrejas ◽  
...  

Cognitive maternal adaptation during pregnancy may influence biological variables, maternal psychological, and neonatal health. We hypothesized that pregnant women with numerous general resources and less negative emotions would have a better coping with a positive influence on neonatal birth weight and maternal psychological health. The study included 131 healthy pregnant women. A blood sample was obtained in the first trimester to assess biological variables (polyphenols, hematological and biochemical parameters). Psychological variables (negative affect, anxiety, optimism, resilience, family–work conflicts, pregnancy concerns, general resources, and life satisfaction) were evaluated at several time points along gestation, and birth weight was recorded. Hierarchical linear regression models were used to associate the above parameters with maternal psychological outcome at the end of gestation (depression, resilience, and optimism) and neonatal outcome (birth weight). Maternal depression was associated with leukocytes (β = 0.08 ± 0.03, p-value = 0.003), cholesterol (β = 0.01 ± 0.002, p-value = 0.026), and pregnancy concerns (β = 0.31 ± 0.09, p-value = 0.001). Maternal resilience was associated with leukocytes (β = −0.14 ± 0.09, p-value = 0.010) and life satisfaction (β = 0.82 ± 0.08, p-value = 0.001), and maternal optimism was associated with polyphenol levels (β = 0.002 ± 0.001, p-value = 0.018) and life satisfaction (β = 0.49 ± 0.04, p-value = 0.001). Birth weight was associated with maternal resilience (β = 370.2 ± 97.0, p-value = 0.001), red blood cells (β = 480.3 ± 144.4, p-value = 0.001), and life satisfaction (β = 423.3 ± 32.6, p-value = 0.001). We found associations between maternal psychological, blood variables, and birth weight and maternal depression. This study reveals the relevance of psychological health during pregnancy for maternal and neonatal outcome, and it emphasizes the need to consider it in preventive policies in the obstetric field.


2020 ◽  
Vol 1 (1) ◽  
pp. 16
Author(s):  
Hatijar Hatijar

Low birth weight babies are babies born with a weight less than 2500 grams. LBW (low birth weight) affects the high mortality rate in infants and is at risk of experiencing obstacles in growth and development. LBW is generally caused due to lack of nutrition and nutritional needs from mother to fetus while pregnant women aged less than 20 years and more than 35 years have the risk of giving birth to LBW. The purpose of this study is to determine the risk factors that cause LBW based on maternal age and nutritional status. The research method used was observational with a cross sectional study approach. The sampling technique was random sampling at the Regional Haji Makassar General Hospital in the January to July 2015 period with a total sample of 65 people. Analysis using the Chi Square Test. The results showed that there was a relationship between maternal age, nutritional status of LBW with a value (p value = 0.00 <α = 0.05). Maternal age and nutritional status are factors that influence low birth weight where the results of the study indicate that there is a relationship between maternal age and nutritional status on the incidence of low birth weight. To reduce the incidence of low birth weight, it is necessary to increase counseling about the causes of low birth weight babies by health workers, especially midwives to pregnant women to prevent the risk of low birth weight birth.


1979 ◽  
Vol 32 (1) ◽  
pp. 21 ◽  
Author(s):  
H Stunzi ◽  
DD Perrin ◽  
T Teitei ◽  
RLN Harris

Complex formation of the biologically active amino acid L-mimosine [α-amino-β-(3-hydroxy-4-oxo-1,4-dihydropyridin-1-yl)propanoic acid (1)], mimosinic acid (2), mimosine methyl ether (9) and 3-hydroxy-1-methylpyridin-4(1H)-one (4) with Cu2+, Zn2+, Cd2+ and Pb2+ was studied. Stability constants were determined by potentiometric titration in 0.15M KNOB3 as inert electrolyte at 37�. In the monomeric complexes formed by the mimosine derivatives, metal binding by the hydroxypyridone moiety was favoured relative to the amino acid group. With mimosine, dimeric complexes were major species. Under physiological conditions, mimosine binds copper and zinc ions more strongly than do simpler amino acids.


2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Xincun Zhang ◽  
Fan Yue ◽  
Hui Li ◽  
Yan Huang ◽  
Yi Zhang ◽  
...  

We systematically investigated the reversibility, time lapse, and oxygenation-deoxygenation properties of 15 naturalα-amino acid–Co(II) complexes through UV-vis spectrophotometer, polarographic oxygen electrode, and DFT calculations, respectively, to explore the relationship between the coordinating structure and reversible oxygenation ofα-amino acid–Co(II) complexes. Results revealed that theα-amino acid structure plays a key role in the reversible oxygenation properties of these complexes. The specific configuration of theα-amino acid group affects theeg1electron of Co(II) transfer to theπ⁎orbit of O2; this phenomenon also favors the reversible formation and dissociation of Co–O2bond when O2coordinates with Co(II) complexes. Therefore, the co-coordination of amino and carboxyl groups is a determinant of Co complexes to absorb O2reversibly. The group adjacent to theα-amino acid unit evidently influences the dioxygen affinity and antioxidation ability of the complexes. The presence of amino (or imino) and hydroxy groups adjacent to theα-amino acid group increases the oxygenation-deoxygenation rate and the number of reversible cycles. Our findings demonstrate a new mechanism to develop reversible oxygenation complexes and to reveal the oxygenation of oxygen carriers.


2020 ◽  
Author(s):  
Lila Otani ◽  
Hiroki Nishi ◽  
Ayaka Koyama ◽  
Yuta Akasaka ◽  
Yusuke Taguchi ◽  
...  

Abstract Background Dietary protein deficiency and amino acid uimbalance cause hepatic fat accumulation. We previously demonstrated that only arginine deficiency as well as total amino acid deficiency in a diet caused significant hepatic triglyceride (TG) accumulation in young Wistar rats. In this study, we explored the mechanisms of this fatty liver formation using these two models. Methods A low-total-amino acid diet (equivalent to 5% protein) and a low-arginine diet (solely the arginine content alone is as low as the low-total-amino acid diet) to the rats for 2 weeks. Results There was substantially greater hepatic TG accumulation in the low-arginine group than in the low-total-amino acid group. The low-total-amino-acid diet potentiated insulin signals in the liver and enhanced de novo lipogenesis. By contrast, the low-arginine diet inhibited hepatic very-low-density lipoprotein secretion, without affecting hepatic insulin signaling and lipogenesis. Conclusions We conclude that, although the arginine intake of the low-arginine group was as low as that of the low-total-amino-acid group, these two diets developed a fatty liver via completely different mechanisms. The potentiation of insulin signaling and resultant increases in fatty acid synthesis seem to drive the effects of a low-protein diet, whereas lower VLDL secretion may be the main causes of low-arginine diet-induced TG accumulation in the liver.


2021 ◽  
Author(s):  
Devdatt Pitale

Abstract Introduction: Nutrition during pregnancy plays an important role for an optimum outcome of pregnancy. Women may be malnourished even before they become pregnant and this may further adversely affect the pregnancy. Maternal undernutrition can lead to poor intrauterine growth and low weight of the baby at birth. Moreover, the leading causes for maternal deaths like hemorrhage and infection are related directly or indirectly to nutrition. Aim of the Study: To study the impact of existing food habits on pregnancy outcome in a south Indian population. Materials and Methods: This prospective study was conducted at a tertiary health care and research institute in India. From the antenatal clinic, 350 women who satisfied the following inclusion and exclusion criteria were admitted to the study. Results: The majority of pregnant women belonged to the age group of 21-25 yrs (47%) followed by the 26-30 yrs age group (40%).The number of teenage pregnancies was 30 (8%) whereas 5% of pregnant women belong the age group of 31-35 yrs.83% of the study population belonged to the low socioeconomic class. Majority of the babies (66%) had the birth weight in the range of 2.5-2.9 kgs. 29 % of babies had birth weight in the range of 3-3.5 kgs. There was a significant association (p value < 0.05) between the socioeconomic status of the mother, parity and her calorie intake. The present study found a statistically significant association between the maternal nutritional status, the birth weight of the baby and the need for NICU admission (p value < 0.05). Conclusion: Maternal food habits have an impact on the pregnancy outcome. Maternal food habits are influenced by many factors like socioeconomic status, parity, social food taboos and pregnancy itself. The pregnancy outcomes like birth weight, need for NICU admission and postnatal complications are influenced by maternal nutritional status.


2021 ◽  
Vol 7 (4) ◽  
pp. 818-823
Author(s):  
Muhammad Subaim ◽  
Lidya Ariyanti

Background : Infant mortality occurs in perinatal insanction (0 - 6 days), followed by death in neonatal indancy (7 – 28 days) and infant time (>28 days-<1year). The cause of death of perinatal babies in Lampung Province in 2013 was caused by asphyxia by 37.14% and the largest neonatal death was caused by BBLR by 28.18%.Purpose : Known correlation of weight gain of mothers while pregnant with the results of baby birth weight in Ambon Market Bandar Lampung Year 2019Methods: Quantitative research type, analytical survey research design with cross sectional approach. The population of 108 pregnant women based on the slovin formula was obtained by a sample of 85 respondents, sampling techniques using simple random sampling.Analyze univariate data and bivariate statistical tests using chi squaretest.Result : From 85 respondents obtained 51 respondents (60.0%) experienced normal weight gain, 34 respondents (40.0%) abnormal weight gain, 58 respondents (68.2%) with normal infant birth weight category, 27 respondents (31.8%) with the weight category of babies born abnormally. Conclusion : Statistical test results using chi square test are obtained p-value = 0.001 (< 0.05) which means there is a correlation of increase in maternal weight while pregnant with the results of baby birth weight in Ambon Market Bandar Lampung City Year 2019. Suggestion Pregnant women can maintain nutritional status from the beginning of the trimester to the end of the trimester through regular consumption of nutrients and energy according to the needs of the condition of the pregnant woman. Keywords : BB Enhancement, Pregnant Women, Baby Birth Weight ABSTRAK Pendahuluan: Kematian bayi terjadi pada masa bayi perinatal (0 - 6 hari), diikuti kematian pada masa bayi neonatal (7 – 28 hari) dan masa bayi (>28 hari-<1tahun). Penyebab kematian bayi perinatal Provinsi Lampung tahun  2013 disebabkan  karena  asfiksia  sebesar 37,14% dan kematian neonatal terbesar disebabkan BBLR sebesar28,18%.Tujuan:Diketahui korelasi peningkatan berat badan ibu saat hamil dengan hasil berat badan lahir bayi di Pasar Ambon Kota Bandar Lampung Tahun 2019.Metode: Jenis penelitian kuantitatif, rancangan penelitian Survei Analitik dengan pendekatan crosssectional. Populasi 108 ibu hamil berdasarkan rumus slovin didapat sampel sebanyak 85 responden, teknik sampling menggunakan simple random sampling. Analisa data univariat dan bivariat, uji statistik menggunakan uji chisquare.Hasil: Dari 85 responden didapat 51 responden (60,0%) mengalami peningkatan berat badan normal, 34 responden (40,0%) mengalami peningkatan berat badan tidak normal, 58 responden (68,2%) dengan kategori berat lahir bayi normal, 27 responden (31,8%) dengan kategori berat bayi lahir tidak normal.Kesimpulan: Hasil uji statistik menggunakan uji chi square didapat nilai p-value = 0,001 (<0.05) yang artinya terdapat korelasi peningkatan berat badan ibu saat hamil dengan hasil berat badan lahir bayi di Pasar Ambon Kota Bandar Lampung Tahun 2019.Saran ibu hamil dapat menjaga status gizi mulai dari awal trimester hingga akhir trimester melalui konsumsi zat gizi dan energi yang teratur sesuai dengan kebutuhan kondisi ibuhamil. Kata Kunci :Peningkatan BB, Ibu Hamil, Berat Badan Lahir Bayi 


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