scholarly journals Effect of smoking on vitamin C and MDA: a cross sectional comparative study

Author(s):  
Chandrashekar V. Kubihal ◽  
Hemalatha D. Naik

Background: Plasma gets exposed to the gases present in the smoke of the cigarette which leads to peroxidation. The ascorbic acid present in the body gets oxidized there is danger of derangement of lipid profile. The measure of malondialdehyde which is formed in lipid peroxidation reaction is indicative of oxidative stress. Oxidative stress seen among the smokers has been attributed to high MDA levels. Objective was to study the effect of smoking on vitamin C and MDA.Methods: Present study was cross sectional study. Two groups of subjects were compared. Out of 100 study subjects, 25 were non smokers and were kept in one group. Remaining 75 were smokers. These two groups were compared to find out how the smoking habit affects the MDA as well as vitamin C levels among them.Results: The levels of MDA were more in smokers compared to those who did not smoke and this difference was significant. The levels of vitamin C were less in smokers compared to those who did not smoke and this difference was significant (p<0.05). It was found that the MDA levels were significantly more among all degrees of smokers. It was less in smokers with mild degree compared to smokers with heavy or moderate degree. Level of vitamin C was more in non smokers compared to smokers. Mild degree of smokers had better levels of vitamin C compared to moderate degree of smokers.Conclusions: Smoking affects the vitamin C levels and MDA levels in the human body.

Author(s):  
Jubina Bency A. T. ◽  
Sarangi . ◽  
Sebastian Roy ◽  
Shalu Sara Mathew ◽  
Shamseena A. ◽  
...  

Background: Hearing loss is a cause of global concern. Percussionists are exposed to greater levels of continuous or intermittent noise than others. Little is known about the relationship between percussion activity and hearing impairment. The early detection of the same and subsequent management makes a significant reduction in the burden of health care services. The objective was to study the proportion of hearing impairment in percussionists in the district of Thrissur using an IOS based mobile application.Methods: A cross sectional study was done on percussionists from Thrissur district who has experience of more than five years and has no congenital or traumatic hearing loss. A predesigned semi structured questionnaire was given and hearing tests were done using a mobile application U hear in a sound proof setting to understand the current state of hearing ability amoung the percussionists.Results: A total of 39 subjects were involved in our study of which all were males. Mean age of our study population was 30.44+12.04. most of them were diagnosed with at least mild degree of hearing loss of one of the ear or both the ears. 15.4% of them had mild degree of hearing loss, 64.1% had moderate degree of hearing loss and 20.5% had severe hearing loss.Conclusions: The study shows percussionists are more exposed to sounds of various frequencies for longer duration, they are more prone to hearing loss. The study brought out that age is directly proportional to hearing loss, music induced hearing loss progress at a rate proportion to the work experience. 


2021 ◽  
Vol 9 (10) ◽  
pp. 2486-2489
Author(s):  
Kshirsagar Shubhangi Sureshkumar ◽  
Anjali D. Turale ◽  
Mangesh Hedau ◽  
Ashish Jaiswal

Ayurveda is the science of life. The main aim of Ayurveda is to maintain the health of a healthy person and to cure the diseased person. For the maintenance of the health of a healthy person, rasayan chikitsa is advised in Ayurve- da. Rasayan chikitsa is the separate branch of Ayurveda, which deals with various aspects of preventive health care. In today’s modern era, the incidence of lifestyle disorders like hypertension, obesity, diabetes mellitus and cardiovascular diseases increased, because of altered dietary and living patterns. Oxidative stress may be respon- sible for most of the diseases. Lack of dietary antioxidants supplements and generation of free radicals induces disease associated with oxidative stress. Oxidative stress is essentially an imbalance between the production of free radicals and the ability of the body to counteract or detoxify their harmful effects through neutralization by antioxidants. Free radicals contain unpaired electrons, and they are unstable and highly reactive. They donate or accept an electron from other molecules, therefore behaving as oxidants. An antioxidant is a stable molecule, enough to donate an electron to rampaging free radical and neutralize it, thus reducing its capacity to damage. Ac-cording to Ayurveda, Amalaki is the best rasayan, tridoshhar. As per modern science, it contains the largest amount of vitamin C (6oomg), and vitamin C has the best antioxidant property. Amalaki rasayan plays an im- portant role as an antioxidant and thus relives oxidative stress, thus helpful in the prevention of many diseases. Keywords: Rasayan, antioxidant, free radicals, Amalaki


Author(s):  
S. Karthikeyan Arasu ◽  
R. Dhivakar ◽  
J. Cibi Chakravarthi ◽  
M. Kausik ◽  
M. Arun Kumar

Background: Stress has become common among the working people in this era. This may lead to further dire psychological consequences such as anxiety, depression etc. India being the information technology (IT) hub with lakhs involved as IT Professionals, there is a need to assess prevalence of professional stress. Not many studies have been conducted regarding this research topic in urban areas. Hence, this study has been exclusively done in Coimbatore which is an urban area in which IT is still developing. Aim of the study was to assess the stress levels of IT professionals in a software company in urban Coimbatore, Tamil Nadu.Methods: Cross–Sectional Study based on a validated questionnaire based on professional life stress scale (PLSS).Results: Out of the 105 employees interviewed 68% were in mild degree of stress. The remaining 32% had moderate degree of stress and none of the participants had high degree of stress.Conclusions: India being a leading sector in IT, its development largely depends on its employees’ physical and mental health. Occupational stress (job stress/work stress) need to be kept harnessed and minimized to provide conducive work environment in the organization.


Author(s):  
AM Sohal Mahamud ◽  
Hassan Md Rizvi ◽  
Md Anisur Rahman ◽  
MZ Hossain

Aims: To assess the pattern of deep bite of orthodontic patients.Material and methods: In this cross sectional study, a total number of 200 sets of pretreatment study cast of patients selected from model store of Orthodontics Department in Dhaka Dental College & Hospital, Mirpur-14, Dhaka-1206, Bangladesh.Results: The study finding show the percentage distribution were as follows, 1% of the sample had open bite, 38.5 % of the sample had normal value of incisor overbite, while 60%patients showed varying values of deep bite. As far as the distribution of these 121 patients in different categories of deep bite is concerned. Maximum number of patients; 50% of these were having mild degree of deep bite while only6.5% showed moderate degree of deep bite and 3.5% showed full coverage of lower incisor crowns.Conclusion: The conclusion that can be drawn from this study is that the commonest overbite relationship in the Bangladeshi sample is the mild overbite (50% patients). Moderate and severe deep bite malocclusions are less prevalent but nearly of the same percentage distribution. In all categories of deep bite, female to male ratio was higher.Ban J Orthod & Dentofac Orthop, April 2014; Vol-4 (1-2), P.16-19


Author(s):  
Medha Mani Saxena ◽  
Ruchi Saxena

Background: Iron deficiency is the most common cause of anemia and is one of the leading risk factors for disability and death worldwide, affecting an estimated 2 billion people Methods: This was cross-sectional study. All the adolescent girls who were given consent to hemoglobin estimation were included in the study. Results: The prevalence of anemia among adolescent girls was found as73.6%. Out of 736 anemic girls, 536 girls were suffering from mild degree of anemia and 173 girls were having moderate degree of anemia. Only 27 girl was found severely anemic. Conclusion: The prevalence of anemia among adolescent girls is alarmingly high in India. Keywords: Prevalence, Anemia, Adolescent.


2021 ◽  
Author(s):  
Juliana de Alencar Fontes ◽  
Gabriel Praxedes Freire ◽  
Gabriel Nascimento ◽  
Pedro Antônio Pereira de Jesus

Background: Hyponatremia is the most common electrolyte disturbance in hospitalized patients and is associated with several unfavorable outcomes, as it promotes cerebral edema and consequent intracranial hypertension. As isn’t clear if there is a causal relationship or if it is only a marker of severity, we described and analyzed the association between sodium disorders, especially hyponatremia, with the severity level of the stroke and the functional condition of discharge of these patients. Methods: We did a cross-sectional study with patients admitted to a stroke unit of a reference hospital in Salvador-Ba between 11/2017 and 03/2020 included in the DISPASS cohort. We classify hyponatremia as serum sodium 145mEq / L. To analyze the association between the variables, Fisher’s exact test was performed. Results: We analyzed 399 patients whose mean age was 62. The mean sodium on admission was 138.2 mEq / L, with 56 patients (14%) with hyponatremia and 11 (3%) with hypernatremia. Among those who had sodium disorders at admission (67), 32 had moderate NIHSS, 24 severe / very severe NIHSS and 11 had mild NIHSS. X² = 2.48, p = 0.443. In addition, of these 67 patients, 13 were discharged and still needed help in daily activities and to walk (mRs 4), 15 were discharged restricted to bed (mRs 5) and 6 died during hospitalization (mRs 6). Therefore, of the 17% who had sodium disorder at admission, more than half had a poor functional outcome. Among those who had hyponatremia (56), 35.7% (20) had severe / very severe stroke, 46.4% (26) had a moderate degree, while only 10 had a mild degree. X² = 1.91, p = 0.53. Conclusions: Although the Fisher Test did not show a significant association (p> 0.05), the frequencies of patients with sodium disorders at admission and classified as having high stroke severity were presented with relevant values, so it is important to carry out further studies to investigate the relationship of these variables.


2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Kwabena Nsiah ◽  
Bernard Bahaah ◽  
Bright Oppong Afranie ◽  
Simon Koffie ◽  
Emmanuel Akowuah ◽  
...  

Introduction. Malaria is a leading cause of mortality among children below 5 years in Ghana. Its parasites are known to cause the degradation of hemoglobin, resulting in the production of reactive oxygen species and hence oxidant stress. Therefore, this study was carried out to compare the levels of oxidative stress between children with complicated and uncomplicated malaria infection in Kumasi, Ghana. Method. Subjects were recruited from hospitals in the Kumasi Metropolis. This was a cross-sectional study, involving 17 complicated malaria subjects, 51 uncomplicated malaria subjects, and 15 nonparasitemic subjects. The rapid diagnostic test (RDT) was used to determine presence or absence of falciparum malaria among the study participants. Blood samples from subjects were used to determine hemoglobin, malondialdehyde (MDA), and vitamin C levels. Results. Majority of the subjects (67.5%) were within the age of 0-5 years. The mean age (±SD) of uncomplicated malaria subjects was 4.32 (±2.81) years, while that of complicated malaria was 4.27 (±2.96). Mean levels of HB decreased significantly in the following order: control subjects > uncomplicated malaria subjects > complicated malaria subjects (p<0.0001). Mean levels of MDA were significantly lower in control subjects compared to complicated malaria subjects (4.62±1.85 versus 6.68±0.70, p=0.0008) and also lowered in uncomplicated malaria subjects compared to complicated malaria (4.50±1.58 versus 6.68±0.70, p<0.0001). There was a statistically significant reduced mean level of vitamin C (p=0.036) in the following order: control subjects > uncomplicated malaria > complicated malaria subjects. However, for the complicated malaria cases, there were significantly higher mean vitamin C levels in females than in males (p<0.001). Conclusion. Malaria progression increases MDA levels and decreases the ascorbate (vitamin C) and hemoglobin levels. It is recommended that future studies should investigate changes in other antioxidant vitamins, like vitamins A and E.


Author(s):  
Shakti Krishan Rajguru ◽  
Jasraj Bohra

Background: This study to find out the prevalence of diabetic retinopathy (DR) among diabetic children with type 1 DM treated with insulin. Methods: This is a cross-sectional study conducted on 50 children with type 1 DM from 1 to 14  years of age. All patients were subjected to full fundus examination and were then classified according to its results into patients with DR and patients without DR. Results: A total of 6 (12.0%) patients were found to have DR. 5 patients had retinopathy in one eye and 1 patients had retinopathy in both eyes. Thus, the total number of eyes with retinopathy was 7 of 100 screened eyes (7.00% of all eyes). Most eyes with retinopathy had a mild degree of NPDR, as it was present in 6 eyes. The other 1eyes had moderate degree of retinopathy Conclusion: The prevalence of DR was 12.0% among all studied patients and 7.00% among all studied eyes. The grade of retinopathy was directly related to the duration of DM, fasting blood glucose, and glycosylated hemoglobin levels. Keywords: DM, DR, Hb1Ac


2020 ◽  
Vol 8 (2) ◽  
pp. 147-154
Author(s):  
Andi Hikma Padaunga ◽  
Sitti Mukarramah

Background: Anemia in pregnancy is one of the conditions where the hemoglobin level is lower than the normal level, which is <11 g /dl. The nutritional adequacy rate of pregnant women have a role in the process of anemia. Diversity in food consumption have an important role in helping to increase iron substance absorption in the body. Objective: To determine the relationship of iron substance and vitamin C adequacy rates with the incidence of anemia in third trimester pregnant women. Methods: This study is observational research with a cross sectional study approach. Sampling by using simple random sampling method for 47 subjects pregnant women of third trimester was determined by using the Lemeshow formula. Data analysis using Chi-Square test.


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