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2022 ◽  
Vol 1 (1) ◽  
pp. 46-48
Author(s):  
SRINIVAS

Most technology development engineers use traditional reliability engineering methods to calibrate the objective functions of their new systems to meet various marketing requirements. Quality is related to products and services to customer satisfaction. Cost reduction and quality improvement is vital to business. Therefore it is no surprise that both consumers and management are so obsessed with the term quality that a separate branch of quality engineering has been developed. Quite a few glorified terminologies have cropped up such as total quality management (TQM), Quality Function Development (QFD), ISO9000, Continuous quality improvement or KAIZEN, and more popularly six sigma design. These are management-oriented and rather incomprehensible to an average engineer. In contrast, Taguchi methods are easier to comprehend and adopt. They are also based on some common sense ideas. The management's interest was evoked owing to the claimed economic consequences of Taguchi methods of reduced cost with improved quality and consequent consumer satisfaction.


Author(s):  
R. M. Rakhimbayeva ◽  
M. K. Tuleubayeva ◽  
K. Zh. Beldibayeva ◽  
G. U. Makenova

The beginning of the global Covid–19 crisis in the world had a negative impact on the economies of various regions and countries, including the development of tourism as a separate branch of the national economy. International tourism experienced a serious downturn in 2020 and early 2021: due to the pandemic and lockdowns, the number of tourists dropped to 98 percent. The article analyzes the level of decline in global tourism, emerging around the world due to the Covid-19 crisis. In the course of the analysis, the author considers vulnerable areas of international tourism on the example of several associated groups. The analysis of the current state and development of international tourism used the method of partial abstraction to collect information and effectively search, group, process and summarize the necessary material. The study of the dynamics of three different economic indicators of the regions of Africa, America, Asia and the Pacific, Europe, the Middle East using a comparative method, including the direct impact of tourism on GDP, exports and international tourism, allows to establish causal relationships and identify and mitigate the problems of international tourism. In particular, it is known that vaccination is a relevant mechanism for solving the emerging underlying problems.


Author(s):  
Anna D. Bakina ◽  

This article discusses the problem of delimiting the notions of biblical lexical item and biblical phraseological unit within the framework of studying the formation and development of biblical phraseology as a separate branch of general phraseology. The author believes that biblical phraseology should to be considered as an independent research area due to the progressive development of the study of phraseology in general, as well as the growing interest among scholars in phraseology of biblical origin and pertinent research materials that have accumulated over the past two decades. To begin with, the paper specifies the status of the biblical phraseological unit as a phraseological unit. Further, the definitions of the above-mentioned notions are analysed and a typology of biblical lexical items and phraseological units of biblical origin is developed based on a review of scholarly works dealing with various aspects of biblical lexical items and biblical phraseological units. Examples of the use of biblical lexical items and biblical phraseological units in English and German texts are provided as illustrations. The research methods applied here include analysis and synthesis, generalization and hypotheticoinductive method; comparative, contextual, and classification methods, as well as analysis of definitions, phraseological identification, and phraseological analysis. The author concludes that biblical lexical item is a broader notion, which includes biblical phraseological units. Biblical lexical items are numerous and diverse in terms of composition and can be presented in the form of multi-level linguistic units (from a word to a sentence), while biblical phraseological units are structured as fixed expressions, from a phrase to a sentence. Thus, a biblical phraseological unit is defined as a fixed reproducible linguistic unit in the form of a phrase or a sentence, having integrity of nomination and integrity of meaning that is etymologically related to the Bible. It is emphasized that the specificity of phraseological units of biblical origin is manifested at the formal, content and functional levels.


2021 ◽  
Vol 25 (4) ◽  
pp. 791-813
Author(s):  
Elena V. Beliakovich

Administrative procedural law is full of numerous and varied procedural time limits which, as time-related categories, define the temporal boundaries of the administrative process and can act as an effective regulator of administrative procedural legal relations. The article examines the concept of time limit in administrative procedural law from the standpoint of integrativeness. It notes that the studied issue was not thoroughly elaborated in science, which appears to result from the young age of administrative procedural law as a separate branch. The research identifies substantial characteristics of the administrative procedural time limit. It reveals the temporal content of time limit in administrative procedural law. A conclusion is reached that the administrative procedural time limit results from the impact of temporal categories on the administrative procedural legal regulation when administrative cases are settled by a public administrative authority and a court. The administrative procedural time limit is recognised as a tool used for temporalizing the administrative process and aimed at ensuring the dynamism of administrative procedural activities through duration, speed, rhythm and cyclicity. The article identified the trend towards the legislative refinement of the administrative procedural time limits. In an integrative sense, the attributes inherent to the administrative procedural time limit reveal the versatility and rich inner content of the concept of time limit in administrative procedural law, which results from the legal synthesis of temporality and authoritative procedural activities of public administrative authorities and courts in settling administrative cases. The article proposed the definitions for the category of time limit in administrative procedural law both in a narrow and broad sense, as well as with an emphasis on the temporal side of the examined category.


Vestnik ◽  
2021 ◽  
pp. 224-227
Author(s):  
М.М. Махамбетчин

Изучение и совершенствование теории ошибок врачей всегда было важно, а сегодня это стало особенно актуальным. В статье указаны три разные позиции во врачебной среде в отношении ошибок врачей. Показаны последовательные изменения в уголовном кодексе в отношении «причинения вреда здоровью» и тенденция криминализации врачебных ошибок. Приводятся сравнение проблемы ошибок в западных странах и СНГ, и меры контроля ошибок. Аргументируется положение о том, что теория врачебных ошибок - отдельный раздел науки. Указаны причины отсутствия теории врачебных ошибок как отдельной науки. В статье перечислены основные положения разработанного варианта теории ошибок врачей. Studying and improving the theory of doctors' mistakes has always been important, and today it has become especially relevant. The article indicates three different positions in the medical environment regarding the mistakes of doctors. Consistent changes in the Criminal Code in relation to "harm to health" and the tendency to criminalize medical errors are shown. A comparison of the problem of errors in Western countries and the CIS, and error control measures are given. The position that the theory of medical errors is a separate branch of science is argued. The reasons for the absence of the theory of medical errors as a separate science are indicated. The article lists the main provisions of the developed version of the theory of doctors' errors.


Agronomy ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 2478
Author(s):  
Zhongyi Xie ◽  
Guo Wen ◽  
Yao Yang ◽  
Haiyan Wang ◽  
Jinying Wang ◽  
...  

Plant leaf morphology has a great impact on plant drought resistance, ornamental research and leaf yield. In this study, we identified a new gene in Nicotiana plumbaginifolia, NpFBA1, that causes leaf curl. The results show that the NpFBA1 protein contains only one unique F-box associated (FBA) domain and does not have an F-box conserved domain. Phylogenetic analysis placed this gene and other Nicotiana FBA genes on a separate branch, and the NpFBA1 protein localized to the nucleus and cytoplasm. The expression of NpFBA1 was induced by black shank pathogen (Phytophthora parasitica var. nicotianae) infection and treatment with salicylic acid (SA) and methyl jasmonate (MeJA). NpFBA1-overexpressing transgenic lines showed leaf curling and aging during the rosette phase. During the bolting period, the leaves were curly and rounded, and the plants were dwarfed. In addition, NpFBA1-overexpressing lines were more susceptible to disease than wild-type (WT) plants. Further studies revealed that overexpression of NpFBA1 significantly downregulated the expression of auxin response factors such as NtARF3 and the lignin synthesis genes NtPAL, NtC4H, NtCAD2, and NtCCR1 in the leaves. In conclusion, NpFBA1 may play a key role in regulating leaf development and the response to pathogen infection.


2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Song-Yi Ning ◽  
Ming-Ming Zhou ◽  
Jie Yang ◽  
Jian Zeng ◽  
Jia-Ping Wang

Abstract Background Rodents are widely distributed and are the natural reservoirs of a diverse group of zoonotic viruses. Thus, analyzing the viral diversity harbored by rodents could assist efforts to predict and reduce the risk of future emergence of zoonotic viral diseases. Rodents are commonly used in animal testing, particularly mice and rats. Experimental rats are important animal models, and a history of pathogenic infections in these animals will directly affect the animal trial results. The pathogenicity of Anellovirus (AV) remains poorly understood due to the lack of a suitable model cell line or animal to support the viral cycle. This study aimed to discover possible anelloviruses from the virome in feces of experimental rats by viral metagenomic technique. Methods Fecal samples were collected from 10 commercial SD rats and pooled into a sample pool and then subjected to libraries construction which was then sequenced on Illumina MiSeq platform. The sequenced reads were analyzed using viral metagenomic analysis pipeline and two novel anelloviruses (AVs) were identified from fecal sample of experimental rats. The prevalence of these two viruses was investigated by conventional PCR. Results The complete genomic sequence of these two AVs were determined and fully characterized, with strain name ratane153-zj1 and ratane153-zj2. The circular genomes of ratane153-zj1 and ratane153-zj2 are 2785 nt and 1930 nt in length, respectively, and both include three ORFs. Ratane153-zj1 closely clustered with members within the genus Wawtorquevirus and formed a separate branch based on the phylogenetic tree constructed over the amino acid sequence of ORF1 of the two AVs identified in this study and other related AVs. While the complete amino acid sequences of ORF1 of ratane153-zj2 (nt 335 to 1390) had the highest sequence identity with an unclassified AV (GenBank No. ATY37438) from Chinchilla lanigera, and they clustered with one AV (GenBank No. QYD02305) belonging to the genus Etatorquevirus from Lynx rufus. Conventional PCR with two sets of specific primers designed based on the two genomes, respectively, showed that they were detectable at a low frequency in cohorts of experimental rats. Conclusion Our study expanded the genome diversity of AVs and provided genetic background information of viruses existed in experimental rats.


2021 ◽  
Author(s):  
◽  
Robert George Wear

<p>1. Abbreviated or direct development is described in Pilumnus novaezelandiae Filhol, 1886 and P. lumpinus Bennett, 1964 (Xanthidae, Pilumninae) from New Zealand. Embryonic development is separated into Nauplius, Metanauplius, and embryonic Zoea stages. In P. novaezelandiae, larvae hatch at a Megalopa stage and are retained beneath the pleon of the female crab. The Megalopa larva and first five juvenile crab stages are described. In P. lumpinus emergent larvae are advanced, much-modified, and non-natatory Zoeae which are not retained by the parent. The Zoea and Megalopa larvae of this species are described. Abbreviated development has little phylogenetic significance among Brachyura, and has probably evolved as a response to habitat requirements of adult crabs. 2. A brief account is given of the systematics and distribution of the New Zealand xanthid crabs Heterozius rotundifrons A. Milne Edwards, 1867, Ozius truncatus H. Milne Edwards, 1834, and of Heteropanope (Pilumnopeus) serratifrons (Kinahan, xanthid Brachyura and to the Megalopa larvae of Heterozius rotundifrons and Ozius truncatus. Notes are given on the seasonal breeding cycle of Heterozius rotundifrons, and the pre-Zoea larva, two Zoea larval stages, and the Megalopa larva reared in the laboratory are described. Ozius truncatus possesses a pre-Zoea larva, four Zoea larval stages, and a Megalopa larva. These have been reared and are described. A key is given for the separation of the Zoea larval stages. The pre-Zoea larva and first stage Zoea larva of Heteropanope Pilumnopeus serratifrons are described. There are probably four zoeal stages in the larval development of this species. 3. The characters of Zoea larvae of the family Xanthidae described up of the present time are critically analysed and considered in relation to the status of currently accepted adult genera and species, the generic groupings used by Monod (1956), and the generic composition of the subfamilies proposed by Balss (1957). Xanthid Zoea larvae fall into two natural groups of genera based on larval characters, the most important being the length of the antennal exopod in relation to that of the spinous process. The first group is equivalent to the subfamily Xanthinae as reconstituted by Balss (1957), but there is no larval evidence suggesting that the "Panopean" genera should be separated from the "Xanthian" genera as suggested by Monod (1956). A second natural group is formed by larvae of the subfamily Menippinae as in Balss (1932, 1957), the subfamily Pilumninae of Balss (1957), and the genus Geryon. Larvae of genera in the subfamily Trapeziinae Miers should be removed from the section Hyperolissa and included in this second natural group. Zoea larvae described from the genera Heteropanope and Pilumnopeus form a separate branch of the second group. Zoea larval evidence does not support Monod's (1956) separation of Eriphia from the "Menippian" group of genera. 4. The first stage Zoea larva Hemiplax hirtipes (Jacquinot, 1853) is described, and present knowledge concerning larvae of crabs of the family Ocypodidae is summarized discussed. No diagnostic character is common to all ocypodid Zoea larvae, but affinities are shown with those of the families Hymenosomidae, Pinnotheridae, and Grapsidae. 5. Pre-Zoea and first stage Zoea larvae hatched from the grapsid crabs Leptograpsus variegatus (Fabricius, 1793), Planes marinus Rathbun, 1915, Hemigrapsus crenulatus (H. Milne Edwards, 1837), H. edwardsi (Hilgendorf, 1882), Cyclograpsus lavauxi H. Milne Edwards, 1853, Helice crassa Dana, 1851, and Plagusia chabrus (Linnaeus, 1764) from New Zealand are described. A key is given for the separation of these larvae. Known Zoea larvae of the family Grapsidae show close affinities with those of the brachyrhynchous families Ocypodidae and Gecarcinidae, and fall into four groups based on larval characters. This system of larval classification agrees with the present arrangement of adult genera into subfamilies except for a division among larvae of the subfamilies Varuninae and Sesarminae. The length of larval life and larval dispersal probably has no bearing on the presence or absence of certain New Zealand species at the Chatham Islands.</p>


2021 ◽  
Author(s):  
◽  
Robert George Wear

<p>1. Abbreviated or direct development is described in Pilumnus novaezelandiae Filhol, 1886 and P. lumpinus Bennett, 1964 (Xanthidae, Pilumninae) from New Zealand. Embryonic development is separated into Nauplius, Metanauplius, and embryonic Zoea stages. In P. novaezelandiae, larvae hatch at a Megalopa stage and are retained beneath the pleon of the female crab. The Megalopa larva and first five juvenile crab stages are described. In P. lumpinus emergent larvae are advanced, much-modified, and non-natatory Zoeae which are not retained by the parent. The Zoea and Megalopa larvae of this species are described. Abbreviated development has little phylogenetic significance among Brachyura, and has probably evolved as a response to habitat requirements of adult crabs. 2. A brief account is given of the systematics and distribution of the New Zealand xanthid crabs Heterozius rotundifrons A. Milne Edwards, 1867, Ozius truncatus H. Milne Edwards, 1834, and of Heteropanope (Pilumnopeus) serratifrons (Kinahan, xanthid Brachyura and to the Megalopa larvae of Heterozius rotundifrons and Ozius truncatus. Notes are given on the seasonal breeding cycle of Heterozius rotundifrons, and the pre-Zoea larva, two Zoea larval stages, and the Megalopa larva reared in the laboratory are described. Ozius truncatus possesses a pre-Zoea larva, four Zoea larval stages, and a Megalopa larva. These have been reared and are described. A key is given for the separation of the Zoea larval stages. The pre-Zoea larva and first stage Zoea larva of Heteropanope Pilumnopeus serratifrons are described. There are probably four zoeal stages in the larval development of this species. 3. The characters of Zoea larvae of the family Xanthidae described up of the present time are critically analysed and considered in relation to the status of currently accepted adult genera and species, the generic groupings used by Monod (1956), and the generic composition of the subfamilies proposed by Balss (1957). Xanthid Zoea larvae fall into two natural groups of genera based on larval characters, the most important being the length of the antennal exopod in relation to that of the spinous process. The first group is equivalent to the subfamily Xanthinae as reconstituted by Balss (1957), but there is no larval evidence suggesting that the "Panopean" genera should be separated from the "Xanthian" genera as suggested by Monod (1956). A second natural group is formed by larvae of the subfamily Menippinae as in Balss (1932, 1957), the subfamily Pilumninae of Balss (1957), and the genus Geryon. Larvae of genera in the subfamily Trapeziinae Miers should be removed from the section Hyperolissa and included in this second natural group. Zoea larvae described from the genera Heteropanope and Pilumnopeus form a separate branch of the second group. Zoea larval evidence does not support Monod's (1956) separation of Eriphia from the "Menippian" group of genera. 4. The first stage Zoea larva Hemiplax hirtipes (Jacquinot, 1853) is described, and present knowledge concerning larvae of crabs of the family Ocypodidae is summarized discussed. No diagnostic character is common to all ocypodid Zoea larvae, but affinities are shown with those of the families Hymenosomidae, Pinnotheridae, and Grapsidae. 5. Pre-Zoea and first stage Zoea larvae hatched from the grapsid crabs Leptograpsus variegatus (Fabricius, 1793), Planes marinus Rathbun, 1915, Hemigrapsus crenulatus (H. Milne Edwards, 1837), H. edwardsi (Hilgendorf, 1882), Cyclograpsus lavauxi H. Milne Edwards, 1853, Helice crassa Dana, 1851, and Plagusia chabrus (Linnaeus, 1764) from New Zealand are described. A key is given for the separation of these larvae. Known Zoea larvae of the family Grapsidae show close affinities with those of the brachyrhynchous families Ocypodidae and Gecarcinidae, and fall into four groups based on larval characters. This system of larval classification agrees with the present arrangement of adult genera into subfamilies except for a division among larvae of the subfamilies Varuninae and Sesarminae. The length of larval life and larval dispersal probably has no bearing on the presence or absence of certain New Zealand species at the Chatham Islands.</p>


2021 ◽  
Vol 900 (1) ◽  
pp. 012037
Author(s):  
L Rudl

Abstract As part of property management, there is a constant increase in operating costs, whether they are new or old buildings. The amount of costs and their growth is related, among other things, to the use of space, the provision of services, the optimization of the working environment and the optimal functionality of the technological parts of the property. In the case of large properties or building complexes, it is therefore a separate branch of Facility Management. As part of the ongoing digitization in the field of construction, the development and implementation of facility management for the subsequent management of the building is also accelerating. There is currently several commercially available software that can be used as an effective tool for organizing, planning, and improving facility processes. The main goal of the work is to conduct a survey of existing and available software for facility management (CAFM) in the market environment of the Czech Republic and compare its functions, working environment in relation to the possibility of use in the construction company environment.


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