scholarly journals Study on acute transfusion related adverse reactions in surgery department

2021 ◽  
Vol 9 (5) ◽  
pp. 1381
Author(s):  
Rejla Rahim ◽  
Sheela Varghese ◽  
Renu Thambi ◽  
M. S. Suma
Keyword(s):  
Blood Transfusion ◽  
Road Traffic ◽  
Blood Component ◽  
Allergic Reactions ◽  
Transfusion Medicine ◽  
Transfusion Reaction ◽  
Cross Sectional ◽  
Medicine Department ◽  
Life Saving ◽  
Surgery Department

Background: Blood transfusion is a routine life- saving medical intervention which is generally regarded as safe when done appropriately. Without blood transfusion, many medical and surgical conditions like anemia, road traffic accidents, obstetric hemorrhage, cardiothoracic surgeries are nearly impossible to manage. However, this life-saving procedure is often associated with adverse effects ranging from minor chills and rigors to life-threatening anaphylaxis. Incidence of transfusion reactions is estimated at 0.001% -10%. The knowledge about the adverse transfusion reaction (ATRs) will help in early identification, management, and prevention of adverse transfusion reactions.Methods: Descriptive cross-sectional study done in 1047 patients, admitted and received at least one unit of whole blood and blood components in the surgery department, Government Medical College, Kottayam during the study period. Information regarding the issue of blood component collected from the transfusion medicine department and the details of the reactions were collected from the patients, and the transfusion reaction workups were done in the transfusion medicine department. The collected data was analysed using Microsoft Excel sheets.Results: The frequency of acute transfusion reaction in this study is 1%. The majority of the reactions were seen with a packed PRBC transfusion. Febrile non-hemolytic transfusion accounted for 54.64% followed by allergic reactions (36.36%) and Transfusion associated cardiac overload (9%).Conclusions: The frequency of ATR in our study was 1%. Febrile non-hemolytic transfusion (FNHTR) and allergic reactions were common patterns followed by transfusion associated cardiac overload (TACO) seen.

scholarly journals Clinical Presentation of Nonhaemolytic Transfusion Reactions

1980 ◽  
Vol 8 (2) ◽  
pp. 125-131 ◽  
Author(s):  
Bryan Rush ◽  
Newton L. Y. Lee
Keyword(s):  
Differential Diagnosis ◽  
Blood Transfusion ◽  
Respiratory Distress ◽  
Hospital Stay ◽  
Clinical Presentation ◽  
Allergic Reactions ◽  
Red Cell ◽  
Transfusion Reaction ◽  
Cell Compatibility ◽  
Transfusion Reactions

Due to the sophistication of red cell compatibility testing, the majority of transfusion reactions are non-haemolytic in origin. This paper reviews the clinical presentation of these reactions, emphasising that blood transfusion reaction must always be considered in the differential diagnosis when a patient develops unexpected complications during his hospital stay. Fever, allergic reactions, respiratory distress, hypotension and jaundice may all be manifestations of a transfusion reaction.

scholarly journals Epidemiological study of animal bite victims and admission in general surgery department, in Southern Odisha: a cross sectional institutional study

2017 ◽  
Vol 4 (10) ◽  
pp. 3470 ◽  
Author(s):  
Sibaprashad Pattanayak ◽  
Tapan Kumar Malla ◽  
Bipin Kishore Bara ◽  
Manoj Kumar Behera
Keyword(s):  
General Surgery ◽  
Cross Sectional Study ◽  
Human Rabies ◽  
Cross Sectional ◽  
Medicine Department ◽  
Medical College ◽  
Recent Estimate ◽  
Animal Bites ◽  
One Year ◽  
Surgery Department

Background: Human rabies continues to be endemic in India and according to recent estimate 20,000 persons die of this disease every year. Hence this study was conducted to know the prevalence and pattern of animal bites during last one year and to determine the rate of admission in Department of Surgery.Methods: This study was conducted in the casualty, Department of Community Medicine, Department of Surgery at M. K. C. G. Medical College, Odisha, India between 1st April 2016 - March 31st, 2017. It was a cross sectional study, where convenient sampling method was used. The sample size was 6242 subjects, above 1year age group selected randomly within last 1 year. The socio demographic characteristics, epidemiological and rate of admission in surgery department were studied.Results: It was found that during last one year, out of 6242 animal bite cases, majority of them were bitten by dogs 4785 (76.66%). It was found that 5617 (90%) are category III bite, 548 (8.78%) are category II bites, 77 (1.23%) are category I bite. Parts of body bitten by animals were limbs 5828 (93.37%), face 312 (5%), back 52 (0.83%). Out of 6242 cases, 348 (5.5%) cases were admitted in General Surgery Department.Conclusions: The prevalence of dog bite was found to be more and was of category III in nature and part of body affected were mostly limbs. Prevalence of bite was nearly equal among male and female. Around 5% of the total animal bite cases required admission in Department of Surgery.  

scholarly journals Study on ABO & Rhesus Blood Groups in Rajshahi Medical College Hospital

1970 ◽  
Vol 17 (1) ◽  
pp. 38-40
Author(s):  
MM Hossain ◽  
SFM Khyirul Ataturk ◽  
ARM Saifuddin Ekram ◽  
M Abul Kalam
Keyword(s):  
Blood Transfusion ◽  
Blood Groups ◽  
Medical College Hospital ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Medicine Department ◽  
Medical College ◽  
Group A ◽  
Group B

About fifty two thousand admitted patients in different wards & cabins of Rajshahi Medical College Hospital are grouped in the Transfusion Medicine Department for the purpose of blood transfusion during the period of July/ 1997 to June/2000. It is found that out of 51966 patients, 16928 (32.38%) are group B, 16704(32.15%) are group O 13005 (25.02%) are group A, & 5329 (10.25%) are group AB, Among those patients, 50141 (96.51%) are Rh D positive, 1828(3.49%) are negative.   doi: 10.3329/taj.v17i1.3488 TAJ 2004; 17(1) : 38-40

scholarly journals Audit of clinical-laboratory practices in haematology and blood transfusion at Muhimbili National Hospital in Tanzania

2012 ◽  
Vol 14 (4) ◽  
Author(s):  
Abel N. Makubi ◽  
Collins Meda ◽  
Alex Magesa ◽  
Peter Minja ◽  
Juliana Mlalasi ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Health Care Services ◽  
Clinical Laboratory ◽  
Donor Selection ◽  
National Standard ◽  
Blood Component ◽  
Muhimbili National Hospital ◽  
National Guidelines ◽  
National Hospital ◽  
Cross Sectional

In Tanzania, there is paucity of data for monitoring laboratory medicine including haematology. This therefore calls for audits of practices in haematology and blood transfusion in order to provide appraise practice and devise strategies that would result in improved quality of health care services.  This descriptive cross-sectional study which audited laboratory practice in haematology and blood transfusion at Muhimbili National Hospital (MNH) aimed at assessing the  pre-analytical stage of laboratory investigations including laboratory request forms and handling specimen processing in the haematology laboratory and assessing the chain from donor selection, blood component processing  to administration of blood during transfusion. A national standard checklist was used to audit the laboratory request forms (LRF), phlebotomists’ practices on handling and assessing the from donor selection to administration of blood during transfusion. Both interview and observations were used. A total of 195 LRF were audited and 100% of had incomplete information such as patients’ identification numbers, time sample ordered, reason for request, summary of clinical assessment and differential diagnoses. The labelling of specimens was poorly done by phlebotomists/clinicians in 82% of the specimens. Also 65% (132/202) of the blood samples delivered in the haematology laboratory did not contain the recommended volume of blood. There was no laboratory request form specific for ordering blood and there were no guidelines for indication of blood transfusion in the wards/clinics. The blood transfusion laboratory section was not participating in external quality assessment and the hospital transfusion committee was not in operation. It is recommended that a referral hospital like MNH should have a transfusion committee to provide an active forum to facilitate communication between those involved with transfusion, monitor, coordinate and audit blood transfusion practices as per national guidelines.

scholarly journals A Study of Frequency and Pattern of Adverse Transfusion Reactions at a Blood Bank in a Tertiary Care Hospital: Towards Hemovigilance

2020 ◽  
Vol 7 (12) ◽  
pp. A576-581
Author(s):  
Suzaan Shajil ◽  
Deepa Sowkur Anandarama Adiga ◽  
Debarshi Saha ◽  
Shrijeet Chakraborty ◽  
Ranjitha Rao
Keyword(s):  
Tertiary Care ◽  
Transfusion Practice ◽  
Blood Bank ◽  
Common Symptom ◽  
Allergic Reactions ◽  
Care Hospital ◽  
Transfusion Reaction ◽  
Surgical Emergencies ◽  
Life Saving ◽  
Transfusion Reactions

Background: Adequate and safe transfusion facility of blood and its components is necessary as blood transfusions are a part of life saving measures in medical and surgical emergencies. However, transfusion practice could result in non-fatal to fatal adverse transfusion reactions (ATR). Therefore, it is important to identify various adverse reactions so that steps can be taken to minimize such reactions and ensure safer transfusion being carried out. Methods: All ATRs reported to the blood bank from January 2013 to December 2016 were reviewed and analysed. The frequency of ATRs and its association with various component types were assessed. Result: During the study period, a total of 199106 units of blood were issued from the blood bank out of which there was an incidence of 77 (0.12%) transfusion reactions. Chills/rigors was the most common symptom (27.3%) of the symptomatic cases followed by pruritis (23.4%) Majority of the transfusion reaction were non haemolytic, 76 (98.7%) cases. One case was of haemolytic transfusion reaction. Among the non-haemolytic transfusion reactions, febrile non haemolytic transfusion reaction (FNHTR) constituted 28 (36.4%) and allergic reactions constituted 41(53.2%). Other transfusion reactions including hypotensive transfusion reaction (HTR), 1 (1.3%) case and transfusion associated dyspnoea (TAD), 6 (7.8%) cases were also seen. The frequency of ATRs was highest with packed red cells (PC) being 75.3% and least with platelet concentrate (PLTC) being 11.7%. Conclusion: The frequency of ATRs in our blood bank was found to be on a lower scale when compared to that of most of the similar studies. Allergic reactions and FNHTR were the most common ATRs seen, introduction of leukoreduction filters would help reduce FNHTRs.

scholarly journals Importance of haemovigilance and reports on transfusion reaction in blood component therapy

2012 ◽  
Vol 65 (1-2) ◽  
pp. 50-53 ◽  
Author(s):  
Jasmina Grujic ◽  
Zdravko Gulan ◽  
Zorana Budakov
Keyword(s):  
Blood Transfusion ◽  
Fresh Frozen Plasma ◽  
Blood Component ◽  
Safe Procedure ◽  
Transfusion Reaction ◽  
Blood Components ◽  
Blood Component Therapy ◽  
Fresh Frozen ◽  
Novi Sad ◽  
Transfusion Reactions

Introduction. Application of blood and blood components throughout decades is very successful and mostly safe procedure in patients? therapy. However, it may lead to unfavourable effects, such as transfusion reactions. Material and Methods. In the period from 2000 to 2009, 180 transfusion reactions were reported at the Department of Clinical Transfusion of the Service for Blood Transfusion of Vojvodina in Novi Sad. The aetiology of transfusion reactions was determined by examining pretransfusion and post-transfusion sample of patient?s blood and by examining the unit of blood component that induced reaction. Results. Out of 180 reported transfusion reactions, 98 (54.4%) were febrile non-haemolytic transfusion reactions, 69 (38.3%) allergic reactions and 2 (1.11%) haemolytic reactions. Blood components that caused most of transfusion reactions were erythrocytes (62.4%), fresh frozen plasma (11.2%) and platelets (14.4%). All patients underwent multiple transfusions. Discussion. The fact that only 0.13% transfusion reactions were reported, compared with data from literature (2-15%), points to the lack of regular reporting of transfusion reactions, as well as the fact that there is only one report of delayed transfusion reaction. Conclusions. To improve and make blood transfusion safer it is necessary to respect all pre-transfusion procedures, constant follow up of blood transfusion must be done and patients with diagnosed non-haemolytic transfusion reaction should be given leukocyte reduced blood components.

scholarly journals Seroprevalence and Trend of HBV, HCV, and HIV Infections among Blood Donors of Fars Province, Iran (2006-2018)

2020 ◽  
Vol 30 (3) ◽  
Author(s):  
Mojtaba Azadbakht ◽  
Masoud Torabi Ardakani ◽  
Marziyeh Delirakbariazar ◽  
Leila Kasraian ◽  
Azad Khaledi ◽  
...  
Keyword(s):  
Blood Transfusion ◽  
Blood Donors ◽  
Hiv Infections ◽  
Cross Sectional Study ◽  
Fars Province ◽  
Chi Square ◽  
Cross Sectional ◽  
Life Saving ◽  
Chi Square Test ◽  
Chisquare Test

BACKGROUND: Blood transfusion is a life-saving procedure; millions of lives are saved each year. However, blood transfusions are associated with certain risks that can lead to adverse consequences. This study aimed to survey the prevalence and trend of hepatitis B virus (HBV), hepatitis C virus (HCV), and Human immunodeficiency virus (HIV) among blood donors of Fars province, Iran (2006-2018).METHODS: This retrospective cross-sectional study was conducted by reviewing the records of the blood transfusion organization of Fars province. A total of 1952478 blood units were screened for transfusion-transmitted infections (TTIs). Then, data were entered into SPSS software (Negare. version 25). Chi-square test was used to compare the sof TTIs among blood donors. Chisquare test for trend was used to analyze the variations in trends of TTIs during this period. Finally, p-values less than 0.05 were considered statistically significant. GraphPad Prism software was used for the depiction of the graphs.RESULTS: Among the 1952478 blood donations within the 13-years, 4479(0.229 %) of donors were HBsAg, HCV Ab, and HIV Ag-Ab positive. The seroprevalence of HBV, HCV, and HIV was 2684(0.137%), 1703(0.087 %), and 92(0.0047%), respectively.CONCLUSION: The current study showed that the overall prevalence of TTIs among blood donors was low and had a descending trend over the years of study.

scholarly journals Identification of Risk Factors Characteristics of Transfusion Reaction

2020 ◽  
Vol 26 (3) ◽  
Author(s):  
Eko Putri Rahajeng ◽  
Raehana Samad ◽  
Rachmawati Muhiddin
Keyword(s):  
Risk Factors ◽  
Blood Transfusion ◽  
Disease Diagnosis ◽  
Careful Consideration ◽  
Blood Component ◽  
Transfusion Reaction ◽  
History Of ◽  
Age Range ◽  
Descriptive Method ◽  
Transfusion Reactions

Blood transfusion is an important part of health care. A blood transfusion can be carried out after careful consideration of its risks and benefits. One of the important considerations for blood transfusion is adverse transfusion reaction. Several risk factors for a transfusion reaction are age, gender, repeated transfusion, disease diagnosis, type of blood component, and blood incompatibility. This research is a descriptive study performed at Blood Bank Dr. Wahidin Sudirohusodo Hospital, Makassar, from January to December 2017. The subjects were all patients reported to have an acute transfusion, totaling 104 subjects. The descriptive method was carried out by the calculation of frequency distribution. From January to December 2017, 104 patients with transfusion reactions were obtained, predominantly were male (53.8%), with the lowest age range of ≥ 60 years (27.9%), packed red cell as the most found blood components (82.4%), a history of previous transfusion reactions (72.1%), and a diagnosis of malignancy (53.9%). The history of repeated transfusions is the most common risk factor compared to age, gender, blood component, and patient diagnosis.

scholarly journals The Distribution of Abo and Rhesus Blood Groups Among Blood Donor Attending Transfusion Medicine Department of Dhaka Medical College Hospital in 2014

2016 ◽  
Vol 24 (1) ◽  
pp. 53-56
Author(s):  
Shanaz Karim ◽  
Md Mazharul Hoque ◽  
Ehteshamul Hoque ◽  
Hussne Ara Begum ◽  
Syeda Masooma Rahman ◽  
...  
Keyword(s):  
Blood Group ◽  
Blood Donor ◽  
Blood Donors ◽  
Blood Groups ◽  
Medical College Hospital ◽  
Transfusion Medicine ◽  
College Hospital ◽  
Cross Sectional ◽  
Medicine Department ◽  
Medical College

Objective: This study was aimed to identify the distribution patterns of ABO and Rh-D blood group among the blood donor attending at transfusion medicine department DMCHin order to promote social awareness and safe blood transfusion among the population.Method: It was a cross sectional study conducted in the Department of Transfusion Medicine, Dhaka Medical College Hospital, Dhaka, from January to December 2014. After proper ethical consideration, a total of 39,512 blood donors were included in this study. They were selected irrespective of age and sex by systematic random sampling. ABO and Rh-D blood groups were determined by the antigen antibody agglutination test in our blood bank by standard tile techniques.Results: Among 39,512 blood donors male blood donors were 31,602(79.98%), female blood donors were 7,910(20.01%).14,817(37.5%) blood donor were identified as having blood group B, while 12,565 (31.8%) were blood group O, 8614( 21.80%) and3516( 8.9% )were blood group A and AB respectively. Rh-D positive were 38,247(96.79%) and Rh-D negative were 1,265(3.2%).J Dhaka Medical College, Vol. 24, No.1, April, 2015, Page 53-56

scholarly journals Assessment of recipients’ characteristics, transfusion appropriateness, and utilization pattern of blood and blood products in Jimma Medical Center, Jimma, Ethiopia

PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250623
Author(s):  
Tufa Feyisa ◽  
Girum Tesfaye Kiya ◽  
Wondimagegn Adissu Maleko
Keyword(s):  
Blood Transfusion ◽  
Whole Blood ◽  
Medical Center ◽  
Reproductive Age ◽  
Blood Type ◽  
Blood Component ◽  
Service Improvement ◽  
Total Blood ◽  
Cross Sectional ◽  
Blood Utilization

Background As blood transfusion remains life-saving and is being frequently prescribed, a greater number of its practice is unnecessary or inappropriate. This important clinical intervention is reported as one of the five overused medical treatments, with gross over-ordering and whole blood transfusions as the sole component being common in developing countries. Study of recipient’s demographics, clinical conditions, appropriate blood utilization, and continuous clinical audits for quality assurance and service improvement plan are important factors to this practice. This study was designed to assess the recipient’s characteristics, blood type distributions, appropriateness of blood transfusion, and utilization practice of the big medical center. Methods Institution based cross-sectional study was conducted from February 1 to June 30, 2018. Data were collected using a structured data collection format prepared for this study. All transfusion prescriptions were followed from requisition up to completion. Patient’s age, sex, requesting departments, hemodynamics, number and component of units requested and issued, and units transfused were collected. Transfusion appropriateness was assessed by a criterion-based method while blood utilization was calculated. Results A total of 545 units of blood for 425 patients were cross-matched of the 809 units of total blood prescribed. The mean and median age of transfused individuals was found to be 27.47 ±15.28 years and 26 years respectively, and 65.4% females most in reproductive age groups. O and A Rhesus-positive blood types were the two major blood groups observed. Overall 82.1% of transfusions were appropriate; while only 27.8% of patients received appropriate components as 96.5% of individuals received a whole blood transfusion. Significant blood utilization was recorded with a C/T ratio of 1.05, TP% of 100%, and TI of 1.23. Conclusion Much of the transfusion recipients were relatively young aged and females, most in the reproductive age group. Although whole blood was used as a sole component, significant blood transfusion utilization and appropriateness were recorded; while appropriate component transfusion was recorded to be significantly low. Local transfusion guidelines and appropriate component preparation and utilization are required to improve the sub-optimal blood component transfusion practice.

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