scholarly journals Study of treatment outcome of tuberculosis among HIV co-infected patients: a cross sectional study in Aurangabad city, Maharashtra

2017 ◽  
Vol 4 (12) ◽  
pp. 4466 ◽  
Author(s):  
Prashant D. Warkari ◽  
Mahavir P. Nakel ◽  
Swati M. Mahajan ◽  
Sangita A. Adchitre
Keyword(s):  
Treatment Outcome ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Rapid Progression ◽  
People Living With Hiv ◽  
Age Group ◽  
Sectional Study ◽  
Hiv Status ◽  
Cross Sectional ◽  
Important Conclusion

Background: Tuberculosis is the most common presenting illness among people living with HIV, including those who are taking anti-retroviral treatment. There were an estimated 1.2 million HIV positive new TB cases globally in 2014. Around 74% of these infected people live in sub-Saharan Africa. Aim and objectives were to study the treatment outcome of tuberculosis among HIV co-infected patients; to assess the outcome of TB treatment in TB patients with respect to their HIV status and to study the underlying factors influencing the outcome rates. Methods: A descriptive cross-sectional study was designed and conducted in Municipal Corporation area, Aurangabad. For this study, HIV co-infected patients registered at city Tuberculosis Centre, Aurangabad were noted and thus information only on TB-HIV status of patients was collected. Results: In this study majority of the study participants were in the age group between 35 and 49 years (45.98%); which is in the reproductive age group. HIV-TB co-infected in this region was mostly males (60.92%). Conclusions: Important conclusion of the study is that very few patients got cured off TB among TB-HIV co-infected patients. One of the reasons could be immunosuppression of HIV patients make them vulnerable for getting active TB and its rapid progression. All the rates i.e. death, default & transfer rate are all above the standard rate i.e. 5% as per RNTCP guidelines. 

scholarly journals Cross-sectional study of population-specific streptococcal antibody titres in Uganda

2020 ◽  
Vol 105 (9) ◽  
pp. 825-829 ◽  
Author(s):  
Emmy Okello ◽  
Meghna Murali ◽  
Joselyn Rwebembera ◽  
Jenifer Atala ◽  
Asha C Bowen ◽  
...  
Keyword(s):  
Normal Values ◽  
Cross Sectional Study ◽  
Capital City ◽  
Sub Saharan Africa ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Limit Values ◽  
Upper Limit ◽  
Antibody Titres

ObjectiveDespite substantial variation of streptococcal antibody titres among global populations, there is no data on normal values in sub-Saharan Africa. The objective of this study was to establish normal values for antistreptolysin O (ASO) and antideoxyribonuclease B (ADB) antibodies in Uganda.DesignThis was an observational cross-sectional study.SettingThis study was conducted at Mulago National Referral Hospital, which is located in the capital city, Kampala, and includes the Uganda Heart Institute.PatientsParticipants (aged 0–50 years) were recruited. Of 428 participants, 22 were excluded from analysis, and 183 (44.4%) of the remaining were children aged 5–15 years.Main outcome measuresASO was measured in-country by nephelometric technique. ADB samples were sent to Australia (PathWest) for analysis by enzyme inhibition assay: 80% upper limit values were established.ResultsThe median ASO titre in this age group was 220 IU/mL, with the 80th percentile value of 389 IU/mL. The median ADB titre in this age group was 375 IU/mL, with the 80th percentile value of 568 IU/mL.ConclusionsThe estimated Ugandan paediatric population standardised 80% upper-limit-of-normal ASO and ADB titres is higher than many global populations. Appropriateness of using population-specific antibody cutoffs is yet to be determined and has important implications for the sensitivity and specificity of rheumatic fever diagnosis.

scholarly journals COVID-19 Mortality in Women and Men in Sub-Saharan Africa: A Cross Sectional Study

2021 ◽  
Author(s):  
Jyoti Dalal ◽  
Isotta Triulzi ◽  
Ananthu James ◽  
Benedict Nguimbis ◽  
Gabriela Guizzo Dri ◽  
...  
Keyword(s):  
Public Health ◽  
Case Fatality ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Age Group ◽  
Sectional Study ◽  
Public Health Response ◽  
Cross Sectional ◽  
Credible Intervals ◽  
Sub Saharan

Objective: To investigate differences of COVID-19 related mortality among women and men across sub-Saharan Africa (SSA) from the beginning of the pandemic. Design: A cross sectional study. Setting: Data from 20 member nations of the WHO African region until September 1, 2020. Participants: 69,580 cases of COVID-19, stratified by sex (men, n=43071; women, n=26509) and age (0-39 years, n=41682; 40-59 years, n=20757; 60+ years, n=7141). Main outcome measures: We computed the SSA- and country-specific case fatality rates (CFRs) and sex-specific CFR differences across various age groups, using a Bayesian approach. Results: A total of 1,656 (2.4% of total cases reported; 1656/69580) deaths were reported, with men accounting for 1168/1656 (70.5%) of total deaths. In SSA, women had a lower CFR than men (mean CFR<diff> = -0.9%; 95% credible intervals -1.1% to -0.6%). The mean CFR estimates increased with age, with the sex-specific CFR differences being significant among those aged 40 or more (40-59 age-group: mean CFR<diff> = -0.7%; 95% credible intervals -1.1% to -0.2%; 60+ age-group: mean CFR<diff> = -3.9%; 95% credible intervals -5.3% to -2.4%). At the country level, seven of the twenty SSA countries reported significantly lower CFRs among women than men overall. Moreover, corresponding to the age-specific datasets, significantly lower CFRs in women than men were observed in the 60+ age-group in seven countries and 40-59 age-group in one country. Conclusions: Sex and age are important predictors of COVID-19 mortality. Countries should prioritize the collection and use of sex-disaggregated data to understand the evolution of the pandemic. This is essential to design public health interventions and ensure that policies promote a gender sensitive public health response.

scholarly journals Epidemiology of childhood tuberculosis and factors associated with unsuccessful treatment outcomes in Tigray, Ethiopia: a ten-year retrospective cross sectional study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Gebremeskel Mirutse ◽  
Mingwang Fang ◽  
Alemayehu Bayray Kahsay ◽  
Xiao Ma
Keyword(s):  
Treatment Outcome ◽  
Treatment Outcomes ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Hiv Status ◽  
Cross Sectional ◽  
Factors Associated ◽  
The Past ◽  
Unsuccessful Treatment ◽  
Childhood Tb

Abstract Background Childhood TB is an indicator of a recent transmission of the disease in a community and it is estimated to constitute 15–20% of all TB cases in many of developing countries. However, only few studies which dominated by industrial countries were engaged to assess the situation. Therefore, this study was aimed to see epidemiology of childhood TB and factors associated with poor treatment outcome in developing country. Method Using retrospective cross-sectional study design; Socio-demographic and clinical data of children aged less than 15 years old, treated for all forms of TB in the past 10 years (2007–2016) was collected from randomly selected eight public hospitals of Tigray. Then, Univariate logistic regression and adjusted multivariate logistic regressions was done to identify variables which had association with unsuccessful treatment outcomes at P-value less than 0.05. Result In the past 10 years, a total of 13,345 Tuberculosis cases were observed. Of these, 1086 (8.1%) cases were children aged less than 15 years old. Sixty seven (6.2%) cases were smear positive. Among those that tested for HIV, 69 (8.3%) cases were TB/HIV co-infected. Of those with treatment outcome record 746 (88.7%) were successfully treated. Factors like being female (AOR, 1.79; 95% CI, 1.07–3.00), Age 0–5 years (AOR, 3.35; 95% CI, 2.11–5.33), Unknown HIV status (AOR, 2.44; 95% CI, 1.51–3.95) and pulmonary positive case (AOR, 2.56; 95% CI, 1.13–5.77), were more likely to have unsuccessful treatment outcome than their counterparts. Conclusion In Tigray 8.1% all TB cases were children age less than 15 years old. Childhood TB treatment outcome varied with sex, age and HIV status.

Suicidal Death Autopsy Analysis at Dhaka Medical College

1970 ◽  
Vol 40 (1) ◽  
pp. 18-21 ◽  
Author(s):  
MN Hossain ◽  
Z Rahman ◽  
S Akhter
Keyword(s):  
Forensic Medicine ◽  
Causes Of Death ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Medical College ◽  
Autopsy Report ◽  
Common Causes ◽  
Suicidal Death

A cross sectional study was carried out at the department of Forensic Medicine in Dhaka Medical College during the period of January 2008 to December 2009. Data were collected from 3rd copy of the post mortem reports which were preserved in the department of Forensic Medicine with the verbal consent of the doctors who performed autopsy report. During this period total 5114 autopsies were conducted. Out of this 970 cases (19%) were suicidal in nature. It was noticed that all suicidal deaths occurred from 10 years to all age group respectively, but top amongst age group of suicidal deaths occurred in between 21 to 30 years of people. Suicidal deaths are more common in female than male. Suicidal deaths due to hanging is highest, next common causes of death due to organophosphorus compund poisoning. Suicidal deaths by hanging is more in female than male but in poisoning cases male are more lvictimised than female. Objectives of our study are to see the occurrence and methods of suicidal death. DOI: http://dx.doi.org/10.3329/bmj.v40i1.9957 BMJ 2011; 40(1): 18-21

End Organ Damage in Hypertensive Geriatric Age Group: A Cross Sectional Study

2017 ◽  
Vol 1 (3) ◽  
pp. 10-16
Author(s):  
Prakashkumar Kyada ◽  
Kunal Jadhav ◽  
T. K. Biswas ◽  
Varshil Mehta ◽  
Sojib Bin Zaman
Keyword(s):  
Ventricular Hypertrophy ◽  
Organ Damage ◽  
Cross Sectional Study ◽  
Left Ventricular ◽  
Age Group ◽  
Sectional Study ◽  
Isolated Systolic Hypertension ◽  
Cross Sectional ◽  
End Organ Damage ◽  
Common Risk Factors

Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Keywords:  Hypertension,  Isolated Systolic Hypertension, Dyslipidemia.

HIGH PREVALENCE OF MALNUTRITON AND WORM INFECTION AMONG VAN KIEU AND PAKOH CHILDREN AGED 12-36 MONTHS IN DAKRONG DISTRICT, QUANG TRI PROVINCE

2012 ◽  
pp. 129-134
Author(s):  
Thi Lan Tran ◽  
Thi Huong Le ◽  
Xuan Ninh Nguyen
Keyword(s):  
Cross Sectional Study ◽  
Age Group ◽  
Infection Status ◽  
Sectional Study ◽  
Group Recommendation ◽  
Related Factors ◽  
Normal Children ◽  
Cross Sectional ◽  
High Prevalence ◽  
Very High

Objectives: Assess the nutritional status, worm infection status and some related factors among children aged 12-36 months of Dakrong district, Quang Tri province. Subject and method: A cross sectional study was carried out in 2010, in 680 children aged 12-36 months in 4 communes of Dakrong district, Quang Tri province. Results: The malnutrition rate was 55.0% for underweight, 66.5% for stunting and 16.2% for wasting. The prevalence of malnutrition increases by age group. The prevalence of worm infection was 31.6%, the highest prevalence was belong to Ascaris infection (24.6%), followed by Hookworm and Trichuris (6.5% and 6.2%, respectively). The prevalence of worm infection among children under two is very high (27.0%). The prevalence of worm infection was distributed quite equally between the malnutrition children group and normal children group. Recommendation: Early deworming forchildren from 12 months should be considered as important strategy against the malnutrition of children in Dakrong district, Quang Tri province

Prevalence of COVID-19-like Symptoms among People Living with HIV, and Using Antiretroviral Therapy for Prevention and Treatment

2020 ◽  
Vol 18 (5) ◽  
pp. 373-380 ◽  
Author(s):  
SeyedAhmad SeyedAlinaghi ◽  
Maryam Ghadimi ◽  
Mahboubeh Hajiabdolbaghi ◽  
Mehrnaz Rasoolinejad ◽  
Ladan Abbasian ◽  
...  
Keyword(s):  
Respiratory Symptoms ◽  
Antiretroviral Treatment ◽  
Clinical Symptoms ◽  
Cross Sectional Study ◽  
People Living With Hiv ◽  
Shortness Of Breath ◽  
Sectional Study ◽  
Limited Data ◽  
Cross Sectional ◽  
Living With Hiv

Background: COVID-19 has spread globally with remarkable speed, and currently, there is limited data available exploring any aspect of the intersection between HIV and SARSCoV- 2 co-infection. Objective: To estimate the prevalence of clinical symptoms associated with COVID-19 among people living with HIV (PLWH) in Tehran, Iran. Design: Cross-sectional study. Methods: A total of 200 PLWH were recruited through the positive club via sampling, and completed the symptom-based questionnaire for COVID-19, which was delivered by trained peers. Results: Of 200 participants, respiratory symptoms, including cough, sputum, and shortness of breath, were the most prevalent among participants, but only one person developed symptoms collectively suggested COVID-19 and sought treatments. Conclusions: It appears that existing infection with HIV or receiving antiretroviral treatment (ART) might reduce the susceptibility to the infection with SARS-CoV-2 or decrease the severity of the infection acquired. Further research is needed to understand causal mechanisms.

Perfil Epidemiológico de Pacientes Renais Crônicos em Tratamento Conservador em um Hospital Escola do Sul de Minas/ Epidemiological Profile of Chronic Renal Failure Patients on Conservative Treatment in a Hospital in Southern School of Minas

1970 ◽  
Vol 4 (4) ◽  
pp. 49-60
Author(s):  
Camila Dorilêo Negretti ◽  
Pablo Girardeli Mendonça Mesquita ◽  
Nilo César do Vale Baracho
Keyword(s):  
Diabetes Mellitus ◽  
Conservative Treatment ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Control Programs ◽  
Keywords Epidemiology ◽  
Epidemiological Profile ◽  
Grade Iii

Objetivo: Determinar o perfil epidemiológico dos pacientes com Doença Renal Crônica em tratamento conservador no ambulatório do Hospital Escola de Itajubá. Materiais e Métodos: Estudo descritivo, de corte transversal, de abordagem quantitativa. Realizado com 171 pacientes atendidos em tratamento conservador no ambulatório de nefrologia no período de janeiro de 2012 a dezembro de 2013. A coleta objetivou caracterizar idade, sexo, raça, estado civil e procedência. Também foram avaliados dados do primeiro atendimento como: valores de ureia e creatinina, o grau de DRC, a etiologia e o número de retorno. Resultados: Dos doentes renais crônicos avaliados, 50,3% eram do sexo masculino, 88% da raça branca, 54,4% casados e a maioria (70,8%) possuía faixa etária prevalente >60 anos. A maioria dos atendidos, 98,5% pertence a microrregião de referência. Quanto a dados de primeira consulta, o diabetes mellitus foi a principal etiologia (38%). Os valores de ureia e creatinina acima da referência preconizada foi observado na maioria dos pacientes e o grau III de DRC em 31% dos casos. O número médio de retornos após a primeira consulta foi de três retornos em 25,13% dos pacientes. Conclusão: A pesquisa permitiu o conhecimento do perfil epidemiológico dos portadores de DRC em tratamento conservador. Os achados reforçam a necessidade de implementação de políticas voltadas para promoção e prevenção à saúde com divulgação de mais programas de controle para minimizar o surgimento de novos casos da DRC. Palavras-chave: Epidemiologia. Doença Renal Crônica. Tratamento. ABSTRACT.Objective: Determine the epidemiological profile of patients with Chronic Kidney Disease (CKD) on conservative treatment at the Hospital Escola de Itajubá. Materials and Methods: A retrospective, descriptive, cross-sectional study of quantitative approach. It was conducted with 171 patients who were treated in conservative treatment at the nephrology clinic from January 2012 to December 2013. The collection aimed to characterize age, sex, race, marital status and origin. We also evaluated data from the first service as: urea and creatinine values, the degree of CKD the etiology and the number of return. Results: Among the chronic renal patients evaluated, 50.3% were male, 88% Caucasian, 54.4% were married and the majority (70.8%) was the most prevalent age group> 60 years. Most of the patients 98.5% belong to micro region of reference. As the first appointment data, diabetes mellitus was the major cause (38%). The urea and creatinine values above the recommended reference was observed in the majority of patients and the DRC grade III in 31% of cases. The average number of returns after the fisrt visit was three return in 25.13% of patients. Conclusion: The research gave us the knowledge of the epidemiological profile of patients with CKD on dialysis. The findings reinforce the need to implement policies for health promotion and prevention with more disclosure of control programs to minimize the appearance of new cases of CKD. Keywords: Epidemiology. Chronic Kidney Disease.Treatment.

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