scholarly journals A retrospective study on demographic profile and etiology of vitreous hemorrhage

2021 ◽  
Vol 7 (3) ◽  
pp. 583-586
Author(s):  
Amulya Padmini H M ◽  
Deeptha Vasudevan
Keyword(s):  
Socioeconomic Status ◽  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Low Socioeconomic Status ◽  
Rural Areas ◽  
Tertiary Care ◽  
Vitreous Hemorrhage ◽  
Vitreous Haemorrhage ◽  
Demographic Profile ◽  
Open Globe

Vitreous haemorrhage(VH) is due to blood leak from ruptured vessels into the vitreous cavity. It results in painless loss of vision. Visual acuity depends on degree and location of haemorrhage.To study the demographic profile and etiology of all patients with vitreous hemorrhage in tertiary care eye hospital.   Medical records of patients who presented with VH between Jan 2017 to July 2018 were retrospectively reviewed. A detailed analysis of records will be noted.    Out of 47 patients, 35 were males and 12 were females. Common age group affected were more than 60 years with 22 cases followed by that among 40 to 60 years involving 15 eyes. 46 cases were unilateral and 1 was bilateral. Majority of cases was noted from the rural areas with low socioeconomic status. Among the etiological causes proliferative diabetic retinopathy was the major cause (41.6%), followed by retinal vein occlusion (14.5%), rhegmatogenous retinal detachment(RRD) (12.5%), blunt trauma (10.41%) which was major cause among children presenting with vitreous haemorrhage, hypertension (4.16%), Eales disease (4.16%), AMD (4.16%), open globe injury (4.16%), retinal artery microaneurysm (2.08%), and PVD with tear (2.08%).Most common age groups affected were greater than 60 years. Among the 47 cases majority were males. 46 were unilateral and 1 was bilateral. More cases were from the rural areas having lower socioeconomic status. Among the etiological causes proliferative diabetic retinopathy formed the major cause.

Demographic Profile Associated With Malnutrition

2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Adnan Khalil ◽  
Shahid Bashir ◽  
Morad Yaser Al Mostafa
Keyword(s):  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Health Problem ◽  
Rural Areas ◽  
Sampling Technique ◽  
Questionnaire Data ◽  
Low Socioeconomic ◽  
Demographic Profile ◽  
Malnourished Children ◽  
One Year

Worldwide, malnutrition is the severe most health problem leading to the highest rate of disease andmortality among children less than 5 years of age. Objective: To find out the association betweenmalnutrition and demographic profile. Methods: 350 malnourished children were chosen by nonprobabilityconvenient sampling technique from Sir Ganga Ram Hospital, Lahore. Children wereassessed through pre-tested questionnaire. Data were analyzed by SPSS version 21.0. Results: 45%malnourished children were 1-3 years of age, majority of the children were females (52%), 89% childrenwere from rural areas, 82.6% children were from low socioeconomic status, 54.6% mothers wereuneducated, 50% malnourished children were not having their own house, 115 malnourished childrenwere having 3 or more siblings and 89 mothers were having less than one year of pregnancy gap.Conclusions: Low socioeconomic status, illiteracy of mothers, rural area, gap between pregnancy andfemale gender has been found to be linked with malnutrition in children below 5 years of age.

scholarly journals Identification of Diagnostic and Prognostic microRNAs for Recurrent Vitreous Hemorrhage in Patients with Proliferative Diabetic Retinopathy

2019 ◽  
Vol 8 (12) ◽  
pp. 2217 ◽  
Author(s):  
Parviz Mammadzada ◽  
Juliette Bayle ◽  
Johann Gudmundsson ◽  
Anders Kvanta ◽  
Helder André
Keyword(s):  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Vitreous Hemorrhage ◽  
Control Group ◽  
Ocular Tissues ◽  
Recurrent Hemorrhage ◽  
Pars Plana ◽  
And Control ◽  
Insight Into ◽  
Recurrent Vitreous Hemorrhage

MicroRNAs (miRNAs) can provide insight into the pathophysiological states of ocular tissues such as proliferative diabetic retinopathy (PDR). In this study, differences in miRNA expression in vitreous from PDR patients with and without incidence of recurrent vitreous hemorrhage (RVH) after the initial pars-plana vitrectomy (PPV) were analyzed, with the aim of identifying biomarkers for RVH. Fifty-four consented vitreous samples were analyzed from patients undergoing PPV for PDR, of which eighteen samples underwent a second surgery due to RVH. Ten of the sixty-six expressed miRNAs (miRNAs-19a, -20a, -22, -27a, -29a, -93, -126, -128, -130a, and -150) displayed divergences between the PDR vitreous groups and to the control. A significant increase in the miRNA-19a and -27a expression was determined in PDR patients undergoing PPV as compared to the controls. miRNA-20a and -93 were significantly upregulated in primary PPV vitreous samples of patients afflicted with RVH. Moreover, this observed upregulation was not significant between the non-RVH and control group, thus emphasizing the association with RVH incidence. miRNA-19a and -27a were detected as putative vitreous biomarkers for PDR, and elevated levels of miRNA-20a and -93 in vitreous with RVH suggest their biomarker potential for major PDR complications such as recurrent hemorrhage incidence.

Reasons for and Management of Postvitrectomy Vitreous Hemorrhage in Proliferative Diabetic Retinopathy

2010 ◽  
Vol 35 (4) ◽  
pp. 308-313 ◽  
Author(s):  
Hua Yan ◽  
Jing Cui ◽  
Yingjuan Lu ◽  
Jinguo Yu ◽  
Song Chen ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Vitreous Hemorrhage

Endolaserless Vitrectomy With Intravitreal Aflibercept Injection for Proliferative Diabetic Retinopathy-Related Vitreous Hemorrhage (LASER LESS TRIAL)

2018 ◽  
Vol 2 (3) ◽  
pp. 127-137
Author(s):  
Dennis M. Marcus ◽  
Harinderjit Singh ◽  
Davis C. Starnes ◽  
Harveen Walia ◽  
Amina Farooq ◽  
...  
Keyword(s):  
Diabetic Retinopathy ◽  
Proliferative Diabetic Retinopathy ◽  
Vitreous Hemorrhage ◽  
Panretinal Photocoagulation ◽  
Short Term ◽  
Safety And Efficacy ◽  
Intravitreal Aflibercept ◽  
Central Subfield Thickness ◽  
Endothelial Growth Factor

Purpose: For proliferative diabetic retinopathy (PDR) eyes not requiring vitrectomy, Diabetic Retinopathy Clinical Research Protocol S and the CLARITY trial demonstrated better visual function and anatomical outcomes with less proliferative and diabetic macular edema consequences in the antivascular endothelial growth factor groups compared to the panretinal photocoagulation groups. Intravitreal aflibercept injection (IAI) may represent a useful therapy with vitrectomy for PDR-related vitreous hemorrhage (VH) as a viable alternative to intraoperative endolaser during vitrectomy. We will determine the safety and efficacy when aflibercept is used for PDR-related VH with endolaserless vitrectomy. Methods: Evaluation of endolaserless vitrectomy and 2 mg IAI for PDR-related VH. Eyes receive 1 preoperative and intraoperative IAI followed by randomization to a q8week group receiving 4 postoperative q4week IAI followed by q8week IAI or q16week group receiving 2 postoperative q4week IAI followed by q16week IAI. Main Outcome Measures: Herein, we present pooled safety and efficacy outcomes through 4 months. Results: Twenty-one of 24 eyes were randomized. Preoperative average visual acuity (VA) was 36 letters (20/200). At 4-month follow-up, 18 of 21 randomized eyes showed an average VA of 72 letters (20/40) with an average visual gain of 38 (range, 0-84 gain) letters. Average optical coherence tomography (OCT) central subfield thickness (CST) at 1-month postoperative follow-up was 311 µm. Average OCT CST at 4-month follow-up was 272 µm (average thinning of 38 µm). No significant short-term ocular or systemic adverse events were observed through 4 months. Conclusions: Endolaserless vitrectomy with IAI for PDR-related VH demonstrates short-term safety with significant VA improvement.

Nutritional anaemia in children in post supplementation era: A cross sectional study

2021 ◽  
Vol 12 (6) ◽  
pp. 44-49
Author(s):  
Rajesh Kumar ◽  
Manoj Kumar Singh ◽  
Vineet Kumar Singh ◽  
Pankaj Kumar ◽  
Sheo Pratap Singh ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Rural Areas ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Socioeconomic ◽  
Female Children ◽  
B12 Deficiency ◽  
Folate And Vitamin B12

Background: Nutritional anemia is still the primary cause of anemia despite of various nutritional programmes in developing countries. Aims and Objective: The present study was planned to asses Iron, Folate, and Vitamin B12 deficiency anaemia in developing countries. Materials and Methods: This cross-sectional study was conducted at a tertiary care centre in Agra in collaboration with Institute of Genomics and Integrative Biology, New Delhi. Admitted children of age 6 months to 14 years having signs and symptoms of anaemia were included in the study. Sample size calculated was 157. All the cases were subjected to CBC, GBP, serum iron, ferritin, folate and vitamin B12 level estimation. Results: Out of 672 children, 157 children with clinical feature of anaemia were enrolled in the study. Among these 157 children, 52.87% were male. Percent proportion of anaemia was highest among toddlers (27.39%) and lowest in adolescent (10.83%). The maximum cases were of urban area (65.6%) and middle socioeconomic status (47.13%). Most of the children were undernourished/underweight (60.4%). Mean iron level was significantly low in female children, children of rural areas, low socioeconomic status and malnutrition/underweight. Mixed iron, folate and B12 deficiency was found in 48.41%, 30.57% and 22.93% cases respectively. In 24.20% cases no deficiencies were found and were classified as anaemia due to some unspecified causes. Conclusion: Nutritional deficiency anaemia is contributing to a large proportion of anaemic patients. More intensified programmes are needed especially for female children, children of rural areas, low socioeconomic status and malnutrition/underweight.

Poor person and areal socioeconomic status is associated with increased diabetic retinopathy and visual impairment incidence and progression

2020 ◽  
pp. bjophthalmol-2020-316430
Author(s):  
Jin Rong Low ◽  
Alfred Tau Liang Gan ◽  
Eva K Fenwick ◽  
Preeti Gupta ◽  
Tien Y Wong ◽  
...  
Keyword(s):  
Socioeconomic Status ◽  
Diabetic Retinopathy ◽  
Visual Impairment ◽  
Low Socioeconomic Status ◽  
Low Income ◽  
Vision Loss ◽  
Population Based ◽  
Housing Type ◽  
Incidence Risk

BackgroundTo investigate the longitudinal associations between person-level and area-level socioeconomic status (PLSES and ALSES, respectively) with diabetic retinopathy (DR) and visual impairment (VI) in Asians with diabetes mellitus (DM).MethodsIn this population-based cohort study, we included 468 (39.4%) Malays and 721 (60.6%) Indians with DM, with a mean age (SD) of 58.9 (9.1) years; 50.6% were female and the mean follow-up duration was 6.2 (0.9) years. Individual PLSES parameters (education, monthly income and housing type) were quantified using questionnaires. ALSES was assessed using the Socioeconomic Disadvantage Index derived from Singapore’s 2010 areal census (higher scores indicate greater disadvantage). Incident DR and VI were defined as absent at baseline but present at follow-up, while DR and VI progression were defined as a ≥1 step increase in severity category at follow-up. Modified Poisson regression analysis was used to determine the associations of PLSES and ALSES with incidence and progression of DR and VI, adjusting for relevant confounders.ResultsIn multivariable models, per SD increase in ALSES score was associated with greater DR incidence (risk ratio (95% CI) 1.27 (1.13 to 1.44)), DR progression (1.10 (1.00 to 1.20)) and VI incidence (1.10 (1.04 to 1.16)), while lower PLSES variables were associated with increased DR (low income: 1.68 (1.21 to 2.34)) and VI (low income: 1.44 (1.13 to 1.83); ≤4 room housing: 2.00 (1.57 to 2.54)) incidence.ConclusionsWe found that both PLSES and ALSES variables were independently associated with DR incidence, progression and associated vision loss in Asians. Novel intervention strategies targeted at low socioeconomic status communities to decrease rates of DR and VI are warranted.

scholarly journals Socioeconomic status and survival among older adults with dementia and depression

2014 ◽  
Vol 204 (6) ◽  
pp. 436-440 ◽  
Author(s):  
Ruoling Chen ◽  
Zhi Hu ◽  
Li Wei ◽  
Kenneth Wilson
Keyword(s):  
Older Adults ◽  
Socioeconomic Status ◽  
Low Socioeconomic Status ◽  
Rural Areas ◽  
Urban Areas ◽  
Computer Assisted ◽  
Late Life Depression ◽  
People With Dementia ◽  
Risk Of Mortality ◽  
The Impact

BackgroundPeople from lower socioeconomic groups have a higher risk of mortality. The impact of low socioeconomic status on survival among older adults with dementia and depression remains unclear.AimsTo investigate the association between socioeconomic status and mortality in people with dementia and late-life depression in China.MethodUsing Geriatric Mental Status – Automated Geriatric Examination for Computer Assisted Taxonomy (GMS-AGECAT) we interviewed 2978 people aged ⩾60 years in Anhui, China. We characterised baseline socioeconomic status and risk factors and diagnosed 223 people with dementia and 128 with depression. All-cause mortality was followed up over 5.6 years.ResultsIndividuals with dementia living in rural areas had a three times greater risk of mortality (multivariate adjusted hazard ratio (HR) = 2.96, 95% CI 1.45–6.04) than those in urban areas, and for those with depression the HR was 4.15 (95% CI 1.59–10.83). There were similar mortality rates when comparing people with dementia with lowv.high levels of education, occupation and income, but individuals with depression with lowv.high levels had non-significant increases in mortality of 11%, 50% and 55% respectively.ConclusionsOlder adults with dementia and depression living in rural China had a significantly higher risk of mortality than urban counterparts. Interventions should be implemented in rural areas to tackle survival inequality in dementia and depression.

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