scholarly journals Emerging cases of mucormycosis in post Covid-19 disease patients

2021 ◽  
Vol 8 (3) ◽  
pp. 219-223
Author(s):  
Sonu S Ahirwar

Mucormycosis (MC) is a serious threat in this covid-19 pandemic situation; cases of MC continue to increases as post covid-19 disease affliction in India. It is a life-threatening disease that happens due to black mold. Mucormycosis is described as a potentially lethal infection amongst immune-compromised (IC) hosts, particularly in those with diabetes, leukemia, and lymphoma. Mortality rate of MC just doubles in IC host, delayed diagnosis increase the rate of mortality. Mucormycosis is difficult to diagnose which affects outcomes and results in a poor prognosis. The main objective of the study was to detect MC in the clinical species received during or post covid-19 treatment in our laboratory.Basic microbiological methods such as gram stain and KOH smear were used for the detection of MC in the received clinical specimen and morphology was seen in the microscope. The is a cross-sectional observational study conducted in our microbiology laboratory for one month periods during May 15, 2021 to June 15, 2021 in a tertiary care hospital of central India. During study period our microbiology lab received n=35 suspected clinical specimens from N= 27 post covid-19 patients for MC diagnosis over one month period. Out of n=35 specimens, n=8 specimens (obtained from N=5 patients) were positive for MC by gram and KOH smear method and we saw filamentous fungi by conventional microscopic method. The present study concluded that the cases of life threatening MC increase day by day in central India as post complication of covid-19 disease.

Author(s):  
Shyam Govind Rathoriya ◽  
Ankit Kumar Jain ◽  
Kavita A. Shinde

<p class="abstract"><strong>Background:</strong> Dermatophytoses are the infection of keratinized tissues such as the epidermis, hair, and nails caused by a group of closely related filamentous fungi known as dermatophytes.</p><p class="abstract"><strong>Methods:</strong> It was a hospital based cross-sectional study. A total number of 150 clinically diagnosed cases of skin, hair and nail infections were randomly selected from all the age groups and of both the sexes, attending Dermatology Outpatient department of CMCH, Bhopal from January 2016-December 2017.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of total 150 subjects, most common clinical type of dermatophytosis, identified in our study, was tinea corporis in 53 (35.3%) subjects followed by tinea cruris in 34 (22.6%) subjects. 134 (89.3%) subjects were tested positive by direct microscopy (KOH mount) and 69 (46.0%) by culture. Highest KOH mount positivity was seen in patient suffering from tinea corporis (94.3%) followed by tinea cruris (94.1%). Culture positivity was highest with tinea corporis (54.7%) followed by tinea lesions on more than one site (47.3%) and tinea cruris (47.0%). In our study, total 69 culture positive samples were isolated and the most common species isolated was T. rubrum in 41 (59.42%) cases.</p><p><strong>Conclusions:</strong> The present study gives valuable insight regarding clinical and mycological pattern of superficial fungal infections in this region as well as shows the importance of mycological examination of dermatophytosis samples for planning effective management. </p>


2019 ◽  
Vol 6 (7) ◽  
pp. 2533
Author(s):  
Ramanuj Mukherjee ◽  
Vaibhav Agarwal ◽  
Arup Mohanta ◽  
Gouri Mukhopadhyay ◽  
Sudipta Samanta

Background: Being one of the most commonly performed surgery in the modern era, post-operative complications following laparoscopic cholecystectomy deserve special mention. Though not very life threatening, they are quite common. Considering these aspects, this study aims to identify them and possibly a potential remedy for decreasing the incidence in the future.Methods: This is a retrospective, institution-based, observational and cross-sectional analysis conducted in R.G. KAR Medical College and Hospital over 5 years on 1000 patients undergoing surgery. Here we intend to observe the adverse events following laparoscopic cholecystectomy in the post-operative period.Results: Most of the complications were seen in the age group greater than 40 years(63%) followed by the age group 30-40 years (26%).Adverse events were much more common in females (85%) followed by males (15%). The symptoms appeared mostly during 3-7 days post operatively (57%) followed by 20% within the first 6 hours. Non-specific abdominal pain (28%) was the most common adverse event followed by port-site infection in 16.5% cases.Conclusions: Proper pre-anaesthetic check-up with proper instrument handling with proper caution and before closing confirmation of proper placement of clip and no other unintentional injury anywhere can decrease the post-operative complication.


2017 ◽  
Vol 4 (6) ◽  
pp. 1918
Author(s):  
Palachandra A. ◽  
Shashank R. ◽  
Sreelatha C. Y.

Background: Appendicitis is among the most common abdominal conditions requiring admission to emergency surgery departments. It has a life time risk of 6%. Untreated appendicitis may be complicated with development of gangrene or perforation, resulting in high morbidity and mortality rates in almost all age groups. The frequency of appendicitis may show variation by population, age, sex, socioeconomic status, and race. The objective of this study was to know the influence of some demographic factors on perforated appendicitis in a tertiary care hospital.Methods: A descriptive cross sectional was done in a teaching hospital which is a referral center. All the acute appendicitis cases admitted to the hospital between January 2015 to December 2016 were included in the study. A total of 532 acute appendicitis cases were diagnosed based on pathological features and were allocated to either the perforated or non-perforated appendicitis groups.Results: In our study total 532 cases were operated for appendicitis. Among that 294 (56%) were males and 238 (44%) were females with a ratio of 1.27:1.00. The mean age was 26.8±13.2 among non -perforated cases and 22.4±12.3 among perforated cases. In present study, maximum cases were in the age group 21-30 years and perforation was more among >50 years age group (23.3%).Conclusions: Perforation was higher among >50 years age group and in the patients from rural area which was found to be statistically significant. The reasons can be misdiagnosis, delayed diagnosis, financial and transportation problems.


Author(s):  
Vijay Kansara ◽  
Disha Vaja ◽  
Ajesh Desai

Background: Maternal near miss is said to have occurred when women presented with life threatening complication during pregnancy, child birth and within 42 days after delivery, but survive by chance or good institutional care. For identifying near-miss cases five-factor scoring system was used. In 2009 WHO working group has standardized the criteria for selecting these cases. Because maternal mortality is a rare event, it is important to study maternal near-miss as a complement to evaluate and improve the quality of obstetric care. Thus, the study was conducted with the aim of assessing the incidence and causes of maternal near-miss.Methods: A facility-based cross-sectional study was conducted in the department of obstetrics and gynecology in GMERS medical college and hospital, Sola, Ahmedabad from January 1, 2019 to August 31, 2019. All maternal near-miss cases admitted to the hospital during the study period were recruited. World Health Organization criteria were used to identify maternal near-miss cases. The number of maternal near-miss cases over one year per 1000 live births occurring during the same year was calculated to determine the incidence of maternal near-miss. Underlying and contributing causes of maternal near-miss were documented from each participant’s record.Results: During the period of study, 3235 deliveries were done at the institution while 16 cases of near-miss were identified. The prevalence of near-miss case in this study was 0.5%. Near-miss per 1000 delivery was 5%. Maternal death to near miss ratio was 1:2.67. The leading causes of maternal near miss were hypertensive disorders (62%) and haemorrhage (32%) The morbidity was high in un-booked cases.Conclusions: Maternal near miss is good alternative indicator of health care system. Efforts made toward improvement in the management of life-threatening obstetric complications could reduce the occurrence of maternal near-miss problems that occur during hospitalization.


2017 ◽  
Vol 15 (2) ◽  
pp. 6-9
Author(s):  
Husneyara Haque ◽  
Kalpana Kumari Thapa

Introduction: Eclampsia is an acute and life-threatening complication of pregnancy associated with elevated maternal and fetal morbidity and mortality. This study was done with the aim to evaluate the maternal and fetal outcome in eclampsia patients and to observe various factors affecting its occurrence and outcome. Methods: A retrospective cross-sectional hospital based study carried out in Nepalgunj Medical College, Nepalgunj from January 2015 to December 2016. Details and data obtained from maternity register were analysed. All patients with eclampsia were included and fetomaternal outcomes measured in terms of complications. Simple descriptive statistical method was applied for analysis. Result: Out of 6056 pregnant women, 46 had eclampsia with the incidence of 7.59 per 1000 deliveries. 58.7% of study population belonged to age group of 21-30 years followed by 36.96% from age less than 20 years. 78.26% cases were unbooked. 73.91% eclamptic patients were primi gravida and 60.87% had gestational age less than 37 weeks. Half of pregnancies with eclampsia underwent ceasarian for delivery and 30.44% required ICU care. One third women developed eclampsia related complications and 2(4.35%) died. Common complications were atonic postpartum heamorrhage (15.21%), psychosis (8.71%) acute renal failure (4.35%). 60.86% newborn were preterm and 56.52% were low birth weight. In 50% newborn, Apgar score at 5 minutes was less than 7. Fetal death was 10.85%. Conclusion: Eclampsia continues to be one of the prime etiological factors for maternal and fetal morbidity and mortality. Therefore early recognition and proper management are vital to tackle this challenge.


Author(s):  
Rupali A. Patle ◽  
Ashok R. Jadhao ◽  
Priya B. Dhengre ◽  
Manjusha A. Dhoble

Background: The covid pandemic started from Hubei, Wuhan in December 2020 then covered many other countries including India. Understanding the demographic and clinical characteristics of deceased COVID-19 patients could inform public health interventions focusing on preventing mortality due to COVID-19. The present study was done with the objective of studying the socio-demographic and clinical profile of deceased patients with coronavirus disease.Methods: This is a hospital based cross-sectional study on 1190 deceased patients of coronavirus disease in a tertiary care hospital of central India which is a dedicated covid hospital from 11 March 2020 to 28 February 2021. Socio-demographic and clinical characteristics of deceased patients were recorded.Results: Overall case fatality rate was 13.24%. Maximum number of deaths occurred in the month of August 2020 and September 2020 were 372 (31.26%) and 477 (40.08%). It was higher in the males 791 (66.47%) as compared to females 399 (33.53%), but the difference was not significant. The most common symptom was fever on hospitalization 924 (77.65%), followed by generalized weakness 771 (64.79%). 352 (29.58%) patients died within 24 hours of the admission to hospital. Hypertension and type 2 diabetes mellitus were the most prevalent morbidity in 557 (46.80%) and 357 (30.00%). It was found that 232 (19.50%) deceased patients had oxygen saturation less than 50% on admission.Conclusions: Higher age and presence of co-morbidities at the time of admission were significantly associated with mortality.


Author(s):  
Devendra Chikara

Objective: To investigate the clinical profile of patients with allergic rhinitis in Central India. Material and Methods: Tertiary care hospital patients attending the E.N.T. OPD have been taken into account. The history of all sampled patients and the clinical evaluation were detailed and 800 cases were included in this study. Statistical Analysis: They were articulated in terms of plain proportion. Results: The majorities of patients are under the age of 30 years and are in the third decade of life. It was observed that the proportion of blockers was much higher than sneezers and runners. Most of the predisposing factors were seasonal and house dust. Conclusion: Allergic rhinitis can affect the physical, psychological and social aspects as well as the productivity of the job. There is an important need to raise awareness of different types of illness, including prevention, in the community. Keywords: allergic rhinitis, central India, sneezers.


Author(s):  
Priyal H. Tolani ◽  
Sarita K. Wadhva

Background: The emergence of tobacco related diseases is a burgeoning public health problem. Every year, more than 8 million people die from tobacco use worldwide. It is one of the major causes of death and disease in India and accounts for nearly 1.35 million deaths every year. India is also the second largest consumer and producer of tobacco. There is an urgent need to curb tobacco use and reduce the associated morbidities and mortalities. The present study was the first step in the process of generating strategies to control the use of tobacco by estimating the prevalence and pattern of tobacco use in an urban community.Methods: Study was conducted in the field practice area of an urban health training center of a tertiary care hospital. House to house survey was done. Houses were selected by systemic random sampling. All the people above 15 years of age were included in the study, with total subjects interviewed being 590.Results: 371 (62.88%) study subjects were males and 219 (37.19%) were females. The prevalence of tobacco consumption was found to be 34.06%, 28.81% used smokeless form of tobacco and 3.39% were smokers. About 1.86% consumed both forms of tobacco.Conclusions: Prevalence of tobacco consumption particularly of smokeless form was quite high. Identification of high-risk group and their pattern of tobacco consumption is crucial in developing innovative and effective strategies to curb the tobacco epidemic in India.


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