scholarly journals A comparative clinical study on the effect of virechana karma and panchtikta pancha prashritika basti karma in the management of prameha w.s.r. to type ii diabetes

2021 ◽  
Vol 7 (2) ◽  
pp. 89-97
Author(s):  
Rajeev Kumar Pandey ◽  
Santosh kumar Bhatted
Keyword(s):  
Clinical Study ◽  
Type Ii Diabetes ◽  
Sweet Taste ◽  
The Body ◽  
Group Comparison ◽  
Type Ii ◽  
Chronic Disorder ◽  
Comparative Clinical Study ◽  
Oral Hypoglycaemic Drugs ◽  
Excessive Quantity

is a chronic disorder of origin with the vitiation of various body elements like and Diabetes mellitus is similar to which is a subtype of Here the patient voids excessive quantity of urine having concordance with with sweet taste. Insulin and other oral hypoglycaemic drugs are associated with several side effects and they have limited role in preventing the complications like neuropathy, nephropathy, retinopathy etc. Hence an ideal therapy which corrects the basic pathology and prevents the progress of the disease and complications is the need of time. So The explained in Ayurveda seems to be an appropriate solution for the treatment of Prameha.Aacharya Charaka and Sushruta has advised for here accumulate in the lower part of the body owing to the incompetence of the The major factor involved in the of are the in general and in particular hence to remove the and to eliminate the from nearest root is best. is best to improve Agni and is the best treatment to correct Vata.The present clinical study was conducted to evaluate the efficacy of Virechana karma and Basti karma in 90 patients (equally distributed in three group) of diagnosed case of Madhumeha for periods of 3 month. Group comparison was done by ANNOVA test showed that the Virechana was found better to reduce FBS and PPP Basti was found better to reduce PPBS

scholarly journals Role of jalapan in the samprapti and vidhi vihit jalapan in the management of prameha w.s.r. to type-II diabetes mellitus

2020 ◽  
Vol 8 (03) ◽  
Author(s):  
Anjali A. Deshpande
Keyword(s):  
Diabetes Mellitus ◽  
Food Consumption ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
The Body ◽  
Type Ii ◽  
General Rules ◽  
Causative Factors ◽  
Comparative Clinical Study

Present era of urbanization,industrialization is responsible for the stresssful, sendentary lifestyle that makes a person more susceptible to Diabetes Mellitus.The misconceptions about food consumption,indiscriminate intake of liquids are the causative factors of lifestyle disorders like diabetes.Ayurveda is the science which explains scientific process and general rules for the consumption of food through the aaharvidhivisheshayatana and aaharvidhividhan.It also highlights the effect of proper food consumption and effect of  proper water intake on the body. An open labeled add on comparative clinical study was conducted in BSDT’s Ayurved hospital.Thirty diagnosed patients of type II Diabetes mellitus were randomly selected from the OPD of kayachikitsa and enrolled into two groups.Role of jalapan in the samprapti of prameha and vidhi vihit (as per rules described in samhita) jalapan along with the vyadhipratyanik chikitsa were assessed in the management of prameha with special reference to type II diabetes mellitus. Nidanparivarjana is an essential part in the management of disease. It is observed that there is an association between jalapan and prameha and vidhi vihit Jalapan plays an important role in the treatment of prameha.

scholarly journals Outcome of breast cancer patients regarding obesity and complications: Analysis of risk factors

2021 ◽  
Vol 68 (1) ◽  
pp. 77-86
Author(s):  
Iuliana Pantelimon ◽  
◽  
Laurentia Nicoleta Gales ◽  
Maria Daniela Tanasescu ◽  
Irina Nita ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Mass Index ◽  
Prognostic Factors ◽  
Disease Progression ◽  
Body Mass ◽  
Type Ii Diabetes ◽  
The Body ◽  
Proliferation Index ◽  
Her2 Overexpression ◽  
Type Ii

Introduction. Breast cancer is the leading cause of cancer death in Romania. In the context in which the treatments available for this pathology have increased curability, the identification of negative prognostic factors involved in the evolution of this disease seems essential to improve the overall survival as well as the time to disease progression. Aim. The aim of this study is to identify the role of prognostic factors such as ki67 proliferation index, the presence of tumour estrogen receptors, HER2 overexpression, the presence of secondary determinations at diagnosis, the association of obesity and type II diabetes. Methods. 50 patients diagnosed with breast cancer treated in the Elias University Emergency Hospital Bucharest were retrospectively followed, for which the progression was documented at the time of elaboration of this study. Thus, a database was developed in which data were entered on age, body mass index, immunohistochemical characteristics of breast tumours, the presence/absence of metastases at diagnosis and the association of type II diabetes. Statistical calculations were performed to highlight a possible correlation between obesity (quantified by measuring body mass index) and tumour aggressiveness (quantified by ki67 proliferation index) as well as statistical evaluation of potential prognostic factors that would influence time, until the disease progresses. Results. Within this group, no correlation could be established between the presence of an increased body mass index and the value of the ki67 proliferation index (p = 0.38). The mean value of the body mass index for this group of unselected patients was 28.76 ± 4.81 (DS) most patients are therefore overweight or obese. The factors involved in the evolution of breast cancer that influenced the early progression of the disease were: the proliferation index ki67 (p <0.05), the presence of metastases at diagnosis (p < 0.0001) and the association of type II diabetes (p = 0.0085). The value of the body mass index did not influence the time to disease progression according to statistical calculations in this group probably due to the small number of normal weight patients included (p = 0.34).

Relationship between Netrin-1 Levels and Diabetes Mellitus Type 2

2021 ◽  
Vol 19 (10) ◽  
pp. 29-33
Author(s):  
Dr. Mohammed Abdulrazzaq Assi ◽  
Dr. Hanan Jasim Hammood ◽  
Zainab Mahdi Attia
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Diabetes Mellitus Type 2 ◽  
Fasting Blood Glucose ◽  
The Body ◽  
Blood Cholesterol ◽  
Control Group ◽  
Type Ii ◽  
Significant Drop

Objects: The study's purpose was to see if there was a link between netrin.1 and type II diabetes patients. Methodology: The present study carried out on (45) patients affected with diabetes mellitus from (120) persons were examined in the education of Diwaniyah hospital from 6th September to the 4th December 2020. The study includes measurement of the body mass index, fasting blood glucose level, HbA1c, lipid profile and level of netrin-1. Results: Our findings were revealed the netrin-1 level was significantly lower in the diabetes (1205.36±753.09) compared to control group (1477.79±700.26; P < 0.01). Our observations were appeared Significantly higher levels of blood cholesterol, TG, LDL, and VLDL-C and In diabetes individuals, there was a significant drop There was a 0.05 difference in HDL-C levels when compared to healthy controls. Conclusion: These findings indicate that low netrin1 concentration in serum are strongly linked to the occurrence of type II diabetes.

scholarly journals A Comparative Clinical Study to Evaluate the Efficacy of Guduchyadi Kashaya and Rajrukshadipachana Kashaya in the Management of Eka Kushta w.s.r to Psoriasis

2021 ◽  
pp. 1-9
Author(s):  
Moulika Markonda ◽  
Sowmya S.B
Keyword(s):  
Clinical Study ◽  
Skin Disease ◽  
Skin Diseases ◽  
The Body ◽  
Skin Infections ◽  
Curative Effect ◽  
Causative Factors ◽  
Comparative Clinical Study ◽  
Modern Treatment ◽  
Chronic Course

In Ayurveda, all skin diseases have been described under the umbrella of Kushtha. Ekakusta is considered as the most commonest skin disease that can affect an individual. Acharya Charak has described the involvement of Vata-Kapha in Eka Kushtha. In the present study Eka kushtha is compared with psoriasis due to resemblance of signs symptoms and causative factors with it. Psoriasis is a papulosquamous disorder of the skin, characterized by sharply defined erythematosquamous lesions this illness exhibits a prompt response if treated carefully, left it may run a very chronic course extending into larger area of the body. Ayurveda focuses more on curative management than palliative management. The drug used in the treatment of Ayurveda does not have complications like modern treatment. Repeated Sodhana prevent the recurrence of the disease. Similarly various preparations have been advocated for the management of Psoriasis. The drugs used in this study are Guduchyadi Kashaya & Rajrukshadi Pachana Kashaya. Both the Kashayas are said to be effective in skin diseases. As per Yogaratnakara, Guduchyadhi Kwath has been mentioned as one of the drug having curative effect on all types of Kustha. Hence for present study the orally Guduchyadi Kwath is taken for EkaKustha treatment. The drugs in Guduchyadi Kwatha are Kusthaghana, Twachya, Swedal, Tridosh shamaka, as well as with Rasayan properties, which is beneficial to break down the pathogenesis of disease. As per Gadanigraha, as mentioned in Kayachikitsakhanda, Rajvrukshadipachana Kashaya is mentioned for the treatment of Ekakushtha. Ingredients in Rajvrukshadi Pachana Kashaya reduce Kapha dosha and most of them act on the skin. Kwatha dravyas are Rasadushtihara, Kaphapittahara, Deepana, Twachya, and also having antibacterial, antimicrobial, antiparasitic and anti-inflammatory properties, Hence, it is helpful for clearing the skin infections.

scholarly journals Evaluation of sweet taste sensitivity in type-II Diabetes Mellitus patients

2020 ◽  
pp. 10-12
Author(s):  
Z. Naveen Kumar ◽  
B.N.S. Gowri Kumari
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Sweet Taste ◽  
Cross Sectional Study ◽  
Taste Sensitivity ◽  
Diabetic Patients ◽  
Type Ii ◽  
Cross Sectional ◽  
The Mean

Background: The objective is to evaluate the sweet taste sensitivity among type-II diabetes mellitus patients. Methods:  This is a cross sectional study consisted of 227 subjects (127 type-II Diabetic patients & 100 non diabetic individuals) of both the genders and age matched. Sweet taste sensitivity tests were done using different concentrations of glucose solution and compared among the diabetic patients with FBS more than 180mg/dl and diabetic patients with FBS less than 180mg/dl and also compared among the diabetic patients and non diabetic individuals.  The final concentration at which patient was able to perceive the taste was recorded. statistical analysis was done using Student’s unpaired T test. P­values of < 0.05 were considered to be statistically significant. Results: The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245 mg/l and the mean of sweet taste sensitivity in the diabetic patients with FBS <180 mg/dl was 2249mg/l with P<0.001 which is significant. The mean of sweet taste sensitivity among diabetic patients with FBS >180 mg/dl was 6245mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l with P<0.01 which is significant. the mean of sweet taste sensitivity among diabetic patients with FBS <180 mg/dl was 2249 mg/l and the mean of sweet taste sensitivity in the non diabetic individuals was 1979mg/l  with P>0.05 which is not significant. Conclusion: In our study it was concluded that type-II Diabetes Mellitus patients have lesser sensitivity for the sweet taste. Loss of sensitivity leads to the increase in sugar consumption being the risk factor for worsening the disease.

Profil Terapi Antidiabetes Oral Pada Pasien Diabetes Mellitus Tipe II Di Instalasi Rawat Jalan Rumah Sakit Anwar Medika

2021 ◽  
Vol 3 (2) ◽  
pp. 137-150
Author(s):  
Adinugraha Amarullah ◽  
◽  
Dwi Febriyani ◽  
Farida Anwari ◽  
Khurin In Wahyuni ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Prescription Drugs ◽  
Type Ii Diabetes ◽  
Data Retrieval ◽  
Nutritional Therapy ◽  
Type Ii Diabetes Mellitus ◽  
The Body ◽  
Type Ii ◽  
Antidiabetic Therapy ◽  
Data Collection Sheet

Diabetes Mellitus (DM) is a chronic condition because of the body cannot produce insulin normally or insulin cannot work effectively. This damage if chronic occurs will cause complications. In the province of East Java the prevalence of DM sufferers of 2.1% ranks 9th, and prevalence of DM in Sidoarjo is patients with a diagnosis of 3.6% of the total population of East Java. The purpose of this study was to look at the profile of oral antidiabetic therapy in type II diabetes mellitus patients in the outpatient installation of Anwar Medika Hospital. The sampling method used is non random sampling Data retrieval from 17 February to 30 April 2020 with a data collection sheet that has been validated. Management of DM patients consists of 4pillars that is education, nutritional therapy, physical activity and pharmacology. The study was conducted in an outpatient installation of Anwar Medika Hospital with 62 samples that fit the inclusion criteria. The results showed that most patients with type II diabetes mellitus were female, as many as 44 patients (70.96%) of 62 patients. Patients with type II diabetes mellitus who most went to Anwar Medika Hospital and got ADO prescription drugs were patients with an age range of 56-65 years as many as 24 patients (38.70%) of 62 patients. Most of the most commonly prescribed ADO drugs by doctors were Glimepirid 34 (91,89%) and combination of 2 kinds of drugs by 22 patients (88%) out of 62 patients. Most patients use more than 1 drug. It is therefore recommended that pharmacy installation officers at Anwar Medika Hospital can provide an understanding of DM, provide counseling related to medicines prescribed to patients and monitor the success of patient therapy. This research is worthy of ethics with numberNo.633/RSAM/VII/2020

Sweet taste and diet in type II diabetes

1996 ◽  
Vol 60 (1) ◽  
pp. 13-18 ◽  
Author(s):  
Beverly J. Tepper ◽  
Lisa M. Hartfiel ◽  
Stephen H. Schneider
Keyword(s):  
Type Ii Diabetes ◽  
Sweet Taste ◽  
Type Ii

scholarly journals Sex-based differences in hepatic and skeletal muscle triglyceride storage and metabolism

2019 ◽  
Vol 44 (8) ◽  
pp. 805-813 ◽  
Author(s):  
Kayleigh M. Beaudry ◽  
Michaela C. Devries
Keyword(s):  
Skeletal Muscle ◽  
Type Ii Diabetes ◽  
Messenger Rna ◽  
Liver Weight ◽  
The Body ◽  
Type Ii ◽  
Intramyocellular Lipids ◽  
Nonalcoholic Fatty Liver ◽  
The Metabolic Syndrome

Women and men store lipid differently within the body with men storing more fat in the android region and women storing more fat in the gynoid region. Fat is predominately stored in adipose tissue as triacylglycerides (TG); however, TG are also stored in other tissues including the liver and skeletal muscle. Excess hepatic TG storage, defined as a TG concentration >5% of liver weight and known as nonalcoholic fatty liver disease (NAFLD), is related to the metabolic syndrome. Similarly, elevated skeletal muscle TG, termed intramyocellular lipids (IMCL), are related to insulin resistance in obesity and type II diabetes. Men store more hepatic TG than women and, unsurprisingly, NAFLD is more prevalent in men than women. Women store more IMCL than men, yet type II diabetes risk is not greater, which is likely due to the manner in which women store TG within muscle. Sex-based differences in TG storage between men and women are underpinned by differences in messenger RNA expression, protein content, and enzyme activities of skeletal muscle and hepatic lipid metabolic pathways. Furthermore, women have a greater reliance on lipid during exercise because of upregulation of lipid oxidative pathways. The purpose of this review is to discuss the role of sex in mediating lipid storage and metabolism within skeletal muscle and the liver at rest and during exercise and its relationship with metabolic disease.

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