scholarly journals Multiple Mechanical Ventilation: historical review and cost analysis

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yina Faizully Quintero-Gamboa ◽  
Carlos Andrés Aguirre-Rodríguez ◽  
Aradeisy Ibarra-Picón ◽  
Edwin Rua-Ramírez ◽  
Edwin Gilberto Medina-Bejarano

In times of crisis in public health where the resources available in the hospital network are scarce and these must be used to the fullest, innovative ideas arise, which allow multiplying the use of existing resources, as artificial mechanical ventilators can be. These can be used in more than one patient, by attaching a device to distribute the mixture of air and oxygen from the ventilator being used simultaneously (multiple mechanical ventilation). This idea, although innovative, has generated controversy among the medical community, as many fear for the safety of their patients, because attaching such devices to the ventilator loses control over the mechanical ventilation variables of each patient and can only maintain general vigilance over the ventilator. These misgivings about the device have led several researchers to take on the task of verifying the reliability of this flow splitter connector. It is for this reason that this article presents a thorough review of the studies carried out on the subject and additionally shows an analysis of comparative costs between the acquisition of a mechanical ventilator and the flow division system.

2020 ◽  
Author(s):  
Uri Adrian Prync Flato ◽  
Patricia C. dos Santos ◽  
Fábio Manhoso ◽  
Fernanda Mesquita Serva ◽  
Jeferson Dias ◽  
...  

Abstract Background: The current need for pulmonary mechanical ventilation related to COVID-19 exceeds the ability of health systems worldwide to acquire and produce mechanical ventilators. The major cause of mortality in patients with this disease is hypoxemia secondary to an inflammatory storm in the lungs associated with thrombotic events. A partnership was established between the university and the private engineering and industrial automation sector to concept and design novel a low-cost emergency mechanical ventilator that could be rapidly available for use in emergency, transport or low-resource health care system, and attend the urgent demand of artificial respiratory system that is need worldwide. It was evaluated the viability of oxygenation and pulmonary ventilation with an emergency mechanical ventilation device called 10D-EMV in animal experiments. A two-stage sequential adaptive study was conducted in 10 sheep, divided into group I (PEEP valve close to the device) and group II (PEEP valve distal to the device). Each animal underwent mechanical ventilation for a total of 120 minutes. Results: The mean oxygenation in group I and group II were 368 mmHg and 366 mmHg, respectively, while the mean partial pressure of carbon dioxide was 58 mmHg and 48 mmHg. Conclusion: This study demonstrates the viability of the 10D device as a novel proposed emergency mechanical ventilator, in order to attend the pandemics demand. Further clinical studies in humans are needed to assess its safety and efficacy.


Author(s):  
Bilal A. Mateen ◽  
Harrison Wilde ◽  
John M. Dennis ◽  
Andrew Duncan ◽  
Nicholas J. Thomas ◽  
...  

AbstractBackgroundNon-pharmacological interventions were introduced based on modelling studies which suggested that the English National Health Service (NHS) would be overwhelmed by the COVID-19 pandemic. In this study, we describe the pattern of bed occupancy across England during the first wave of the pandemic, January 31st to June 5th 2020.MethodsBed availability and occupancy data was extracted from daily reports submitted by all English secondary care providers, between 27-Mar and 5-June. Two thresholds for ‘safe occupancy’ were utilized (85% as per Royal College of Emergency Medicine and 92% as per NHS Improvement).FindingsAt peak availability, there were 2711 additional beds compatible with mechanical ventilation across England, reflecting a 53% increase in capacity, and occupancy never exceeded 62%. A consequence of the repurposing of beds meant that at the trough, there were 8·7% (8,508) fewer general and acute (G&A) beds across England, but occupancy never exceeded 72%. The closest to (surge) capacity that any trust in England reached was 99·8% for general and acute beds. For beds compatible with mechanical ventilation there were 326 trust-days (3·7%) spent above 85% of surge capacity, and 154 trust-days (1·8%) spent above 92%. 23 trusts spent a cumulative 81 days at 100% saturation of their surge ventilator bed capacity (median number of days per trust = 1 [range: 1 to 17]). However, only 3 STPs (aggregates of geographically co-located trusts) reached 100% saturation of their mechanical ventilation beds.InterpretationThroughout the first wave of the pandemic, an adequate supply of all bed-types existed at a national level. Due to an unequal distribution of bed utilization, many trusts spent a significant period operating above ‘safe-occupancy’ thresholds, despite substantial capacity in geographically co-located trusts; a key operational issue to address in preparing for a potential second wave.FundingThis study received no funding.Research In ContextEvidence Before This StudyWe identified information sources describing COVID-19 related bed and mechanical ventilator demand modelling, as well as bed occupancy during the first wave of the pandemic by performing regular searches of MedRxiv, PubMed and Google, using the terms ‘COVID-19’, ‘mechanical ventilators’, ‘bed occupancy’, ‘England’, ‘UK’, ‘demand’, and ‘non-pharmacological interventions (NPIs)’, until June 20th, 2020. Two UK-specific studies were found that modelled the demand for mechanical ventilators, one of which incorporated sensitivity analysis based on the introduction of NPIs and found that their effects might prevent the healthcare system being overwhelmed. Separately, several news reports were found pertaining to a single hospital that reached ventilator capacity in England during the first wave of the pandemic, however, no single authoritative source was identified detailing impact across all hospital sites in England.Added Value of This StudyThis national study of hospital-level bed occupancy in England provides unique and timely insight into bed-specific resource utilization during the first wave of the COVID-19 pandemic, nationally, and by specific (geographically defined) health footprints. We found evidence of an unequal distribution of resource utilization across England. Although occupancy of beds compatible with mechanical ventilation never exceeded 62% at the national level, 52 (30%) hospitals across England reached 100% saturation at some point during the first wave of the pandemic. Close examination of the geospatial data revealed that in the vast majority of circumstances there was relief capacity in geographically co-located hospitals. Over the first wave it was theoretically possible to markedly reduce (by 95.1%) the number of hospitals at 100% saturation of their mechanical ventilator bed capacity by redistributing patients to nearby hospitals.Implications Of All The Available EvidenceNow-casting using routinely collected administrative data presents a robust approach to rapidly evaluate the effectiveness of national policies introduced to prevent a healthcare system being overwhelmed in the context of a pandemic illness. Early investment in operational field hospital and an independent sector network may yield more overtly positive results in the winter, when G&A occupancy-levels regularly exceed 92% in England, however, during the first wave of the pandemic they were under-utilized. Moreover, in the context of the non-pharmacological interventions utilized during the first wave of COVID-19, demand for beds and mechanical ventilators was much lower than initially predicted, but despite this many trust spent a significant period of time operating above ‘safe-occupancy’ thresholds. This finding demonstrates that it is vital that future demand (prediction) models reflect the nuances of local variation within a healthcare system. Failure to incorporate such geographical variation can misrepresent the likelihood of surpassing availability thresholds by averaging out over regions with relatively lower demand, and presents a key operational issue for policymakers to address in preparing for a potential second wave.


2010 ◽  
Vol 4 (3) ◽  
pp. 199-206 ◽  
Author(s):  
Lewis Rubinson ◽  
Frances Vaughn ◽  
Steve Nelson ◽  
Sam Giordano ◽  
Tom Kallstrom ◽  
...  

ABSTRACTObjective: The supply and distribution of mechanical ventilation capacity is of profound importance for planning for severe public health emergencies. However, the capability of US health systems to provide mechanical ventilation for children and adults remains poorly quantified. The objective of this study was to determine the quantity of adult and pediatric mechanical ventilators at US acute care hospitals.Methods: A total of 5752 US acute care hospitals included in the 2007 American Hospital Association database were surveyed. We measured the quantities of mechanical ventilators and their features.Results: Responding to the survey were 4305 (74.8%) hospitals, which accounted for 83.8% of US intensive care unit beds. Of the 52 118 full-feature mechanical ventilators owned by respondent hospitals, 24 204 (46.4%) are pediatric/neonatal capable. Accounting for nonrespondents, we estimate that there are 62 188 full-feature mechanical ventilators owned by US acute care hospitals. The median number of full-feature mechanical ventilators per 100 000 population for individual states is 19.7 (interquartile ratio 17.2–23.1), ranging from 11.9 to 77.6. The median number of pediatric-capable device full-feature mechanical ventilators per 100 000 population younger than 14 years old is 52.3 (interquartile ratio 43.1–63.9) and the range across states is 22.1 to 206.2. In addition, respondent hospitals reported owning 82 755 ventilators other than full-feature mechanical ventilators; we estimate that there are 98 738 devices other than full-feature ventilators at all of the US acute care hospitals.Conclusions: The number of mechanical ventilators per US population exceeds those reported by other developed countries, but there is wide variation across states in the population-adjusted supply. There are considerably more pediatric-capable ventilators than there are for adults only on a population-adjusted basis.(Disaster Med Public Health Preparedness. 2010;4:199-206)


1987 ◽  
Vol 8 (5) ◽  
pp. 200-203 ◽  
Author(s):  
Theresa A. Goularte ◽  
Marie Manning ◽  
Donald E. Craven

AbstractWe evaluated levels of bacterial colonization in the humidifying cascade reservoirs of 466 mechanical ventilators; 326 reservoirs were cultured after 24 hours and 140 were cultured after 48 hours of continuous mechanical ventilation. Bacterial colonization was absent in 284 (87.1%) of the humidifier reservoirs sampled at 24 hours and 125 (89.3%) of the reservoirs cultured at 48 hours. Levels of bacterial colonization in the remaining humidifiers were low (<100 organisms/mL). The median temperature recorded in the reservoir fluid of 30 different ventilators was 50°C (range 40° to 60°C). In vitro seeding of reservoir fluid at 50°C with 106 organisms/mL of four different species of nosocomial gram-negative bacilli and Staphylococcus aureus demonstrated rapid killing of all five strains over a 6-hour incubation period, and no significant bacterial aerosols were detected. Rates and levels of bacteria in heated humidifier reservoirs are low and nosocomial pathogens survive poorly at the median reservoir temperature of 50°C. We conclude that the heated humidifier reservoir on a mechanical ventilator is an unlikely source of colonization or bacterial aerosols, and therefore it can be changed every 48 hours with the ventilator tubing.


Author(s):  
Blánaid Daly ◽  
Paul Batchelor ◽  
Elizabeth Treasure ◽  
Richard Watt

Public health is a key concern of modern dental practitioners as they continue to play a vital role in the health of populations across the world. The second edition of Essential Dental Public Health identifies the links between clinical practice and public health with a strong emphasis on evidence-based medicine. Fully revised and updated for a second edition, this textbook is split into four parts covering all the need-to-know aspects of the subject: the principles of dental public health, oral epidemiology, prevention and oral health promotion, and the governance and organization of health services. Essential Dental Public Health is an ideal introduction to the field for dentistry undergraduates, as well as being a helpful reference for postgraduates and practitioners.


2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
T Ha ◽  
B Kemp ◽  
M Wallace

Abstract Background University education in Australia and internationally involves teaching diverse students: in terms of age, life experience, previous degrees completed, and level of English competency. In Australia the Bachelors of Public Health (BPH) at The University of Wollongong, epidemiology is a core subject. It aims to equip students with the knowledge and skills needed to design, critique and interpret studies that investigate why different populations experience different health outcomes. A student-centred learning strategy; Hybrid Team Based Learning and Personalised Education teaching strategy (HTBL-PE) was created to maximise academic success. Each phase has a distinct purpose based on learning theories (e.g. TBL, Bloom's taxonomy and Vygotsky). HTBL-PE aims to systematically build students abilities; strengthen self-confidence and belief, by teaching the way students learn and harnessing the capabilities of the team to strengthen the individual. Objectives HTBL-PE was evaluated in spring 2019 in the BPH, where their experiences at the beginning and end of semester were measured. Results In total 73 out of 84 enrolled students provided data at both time-points (87%). At the end of the semester, the vast majority of students indicated their interest in epidemiology had increased (93%), critical thinking had improved (92%), and confidence as independent learners had increased (86%). Outcomes did not differ significantly by gender or across learning styles. More than two thirds of students had already applied learnings from this subject in other settings (67%). Students' final mark for this subject was significantly higher than their Weighted Average Mark (WAM) prior to the semester (+17.4, p &lt; 0.001). Average scores for the subject were &gt; 84/100 with a &lt; 0.5% failure rate. Conclusions HTBL-PE has positive learning outcomes; low failure rates, increased confidence in learning and themselves, increased interest in epidemiology and high overall scores in the subject. Key messages An effective new innovative teaching strategy resulted in a subject average score &gt; 84/100 and &lt;0.5% failure rate. The vast majority of students reported increased confidence as independent lifelong learners, critical thinking, confidence in epidemiology (knowledge, skills, and attitudes) and themselves.


Actuators ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 51
Author(s):  
Jozef Živčák ◽  
Michal Kelemen ◽  
Ivan Virgala ◽  
Peter Marcinko ◽  
Peter Tuleja ◽  
...  

COVID-19 was first identified in December 2019 in Wuhan, China. It mainly affects the respiratory system and can lead to the death of the patient. The motivation for this study was the current pandemic situation and general deficiency of emergency mechanical ventilators. The paper presents the development of a mechanical ventilator and its control algorithm. The main feature of the developed mechanical ventilator is AmbuBag compressed by a pneumatic actuator. The control algorithm is based on an adaptive neuro-fuzzy inference system (ANFIS), which integrates both neural networks and fuzzy logic principles. Mechanical design and hardware design are presented in the paper. Subsequently, there is a description of the process of data collecting and training of the fuzzy controller. The paper also presents a simulation model for verification of the designed control approach. The experimental results provide the verification of the designed control system. The novelty of the paper is, on the one hand, an implementation of the ANFIS controller for AmbuBag pressure control, with a description of training process. On other hand, the paper presents a novel design of a mechanical ventilator, with a detailed description of the hardware and control system. The last contribution of the paper lies in the mathematical and experimental description of AmbuBag for ventilation purposes.


PEDIATRICS ◽  
1991 ◽  
Vol 88 (6) ◽  
pp. 1233-1237
Author(s):  
Lewis H. Margolis

How physicians respond to the promotional activities of the pharmaceutical industry is the subject of ongoing debate and controversy. This paper postulates that the acceptance of gifts in virtually any form violates fundamental duties of the physician of nonmaleficence, fidelity, justice, and self-improvement. The medical community must articulate this position clearly, and it should act accordingly.


PEDIATRICS ◽  
1991 ◽  
Vol 87 (4) ◽  
pp. 565-567
Author(s):  
A. CHARLES BRYAN ◽  
ALISON B. FROESE

Mechanical ventilators have only two functions: to provide a flux to eliminate carbon dioxide from those who will not or cannot breathe and to establish an adequate gas-exchanging volume to reduce shunting. The concept of volume recruitment to reduce shunting goes back at least to Mead and Collier in 1959,1 who showed that without periodic inflations there was a progressive fall in compliance during prolonged mechanical ventilation. Much of the subsequent history of mechanical ventilation in acute lung disease has really been the search for better methods of volume recruitment. The lung has to be inflated past the pressure at which atelectatic lung begins to open and be maintained above its closing pressure (that pressure below which alveoli and airways start to close again).


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