scholarly journals EXPERIMENTAL LOW ENERGY NANOSECOND LASEROTHERAPY AND MICROSURGERY OF MODELING PERIODONTITIS USING MORPHOLOGICAL ANALYSIS

2019 ◽  
Vol 15 (1) ◽  
pp. 80-86
Author(s):  
Андрей Чунихин ◽  
Andrey Chunihin ◽  
Эрнест Базикян ◽  
Ernest Bazikyan

Background. The problem of the treatment of periodontal disease is acute in modern dentistry. The multiplicity of etipathogenetic factors causing the development of periodontitis, malignations associated with the loss of teeth cause the search for new methods of complex therapy of periodontal diseases, including the inclusion of modern laser technologies. Purpose ― comparative assessment of the effect on the regeneration of periodontal tissues of nanosecond laser radiation with a wavelength of 1265 ± 5 nm of traditional photodynamic therapy using morphological and morphometric analysis in an in vivo experiment. Methodology. Modeling of periodontitis in experimental animals was performed using a ligature technique for 7 days. Treatment of periodontitis began with mechanical and drug treatment of pockets, then the animals were divided into three groups. In the first group, a new nanosecond laser device with a wavelength of 1265 ± 5 nm was used for treatment, the second used traditional photodynamic therapy using a chlorine E6 photosensitizer, in the third group until the end of treatment only drug therapy was used. On days 7, 14, 21, a visual assessment of the condition of periodontal tissues in experimental animals, morphological and morphometric analysis were performed. Results. On the 21st day of observation in the main group in the oral cavity, the periodontal regeneration process was completed, in the comparison group there are local pockets of shallow depth with granulation tissue. The morphological study showed that in the main group the number of full blood vessels in the field of view of the microscope at the later stages of treatment is 2.9 times higher than in the comparison group. Conclusions. The results of the study confirmed the need to include laser techniques in the complex therapy of periodontal diseases. The use of new laser technology of nanosecond laser therapy and microsurgery in the treatment of periodontal diseases contributes to shortening the procedure time, shortening the rehabilitation time, and stimulating vascular growth.

2018 ◽  
pp. 28-31
Author(s):  
A.V. Mandych

The abnormalities of maxillodental system take one of the leading places among diseases of the maxillofacial area. Thus, they are diagnosed more than in 50% cases among the younger population and in 30% cases among the adult population.   Most often, there are prerequisites for the incorrect position of individual teeth: anomalies are formed at the genetic level because of heredity of pathologies of size, amount, shape of teeth and size of the jaw bones of the facial skeleton. If the position of the teeth is incorrect, the periodontium retains the occlusal load of the functional injury. Therefore, the aim of our research was to study the prevalence of periodontal tissue diseases in young individuals on the background of crowded teeth. The material and research methods. The study was conducted on the base of Dental Center of Danylo Galytsky Lviv National Medical University during 2015−2017 years. 1146 people at the age from 18 to 44 years were examined. Every participant of research underwent general dental examination, as well as a special examination aimed at clarification of orthodontic treatment. The diagnosis of periodontal tissue diseases was made according to the classification of N. F. Danilevskyi and was determined using paraclinical indicators. The obtained results were worked out statistically using functions of MS Excel and Statistica 6. Results of the research and their discussion. The total number of the examined with orthodontic pathology was found on average in 77.24% of patients (885 people). At the same time, abnormalities of dental jaw system were not detected in about 261 (22.76%) of the examined. As a result of the conducted studies we found that among the examined without dental jaw abnormalities 38.89±.,32% of patients had intact periodontium, that was 1.6 times more for data in individuals with crowding − 23.73±2.00, p<0.01. At the same time, in patients of the main group the prevalence of periodontal tissue diseases was 1.2 times higher than in the examined of the comparative group (76.27±2.00% against 61.11±3.32%, respectively, p<0.01). It should be noted, that with the increase of the age of patients the prevalence of periodontal tissue diseases increased in both study groups, but in patients with crowded teeth this tendency was more pronounced. So, in the younger age group in patients with crowding the prevalence of periodontal diseases was 1.5 times higher in relation to the data of their peers from the comparison group (71.37±3.00% vs. 46.99±5.48%, p<0.01). In 27−35-year-old patients the prevalence of periodontal tissue diseases amounted to 72.38±4.03% of the examined of the main group and 65.62±5.94% of the examined of the comparison group, but the obtained data were not statistically significant, p>0.05. At the same time, in the patients of the main group aged 36−44 years the prevalence of periodontal tissue diseases was maximal and exceeded the value of their peers in the comparison group by 1.2 times (92.08±2.69% vs. 73.91±5.29%, respectively, p<0.01). The analysis of the obtained data allowed to assert that on average crowding of teeth on the upper jaw was found in 237 patients (52.55%) and on the lower jaw in 214 patients (47.45%). Thus, the maximum frequency of crowded teeth on the upper jaw was observed in the examined in the age range of 27−35 years, 60.16±4.41% of patients, with the minimum prevalence of this pathology in the youngest group (18−26 years), 49.34±4, 72%. The analysis of diagnostic structure of periodontal tissue diseases showed that inflammatory diseases of periodontal tissues (gingivitis, localized periodontitis) were found in patients with crowded teeth, on average 1.2 times more often than in patients without orthodontic pathology (42.42±1.88% vs. 36.33±3.54%, respectively, p<0.05). Conclusions. Thus, as a result of the conducted studies, higher prevalence of periodontal tissue diseases was proved in patients with crowding of teeth, which made progress in increasing the age of the examined than in patients without orthodontic pathology.


2020 ◽  
Vol 16 (2) ◽  
pp. 53-58
Author(s):  
Karen Karakov ◽  
Emilia Khachaturyan ◽  
Marat Uzdenov ◽  
Laura Uzdenoba ◽  
Nelli Vanchenko ◽  
...  

Subject. The article presents the data of a comparative analysis of the traditional method of treating chronic generalized periodontitis of mild to moderate severity and with the use of periodontal dressings in combination with an antibacterial photodynamic system. The goal is to study the effectiveness of the methodology of complex therapy for the treatment of periodontal diseases using periodontal dressings and antibacterial photodynamic therapy. Methodology. We observed 120 patients with inflammatory periodontal diseases aged 18 to 55 years (men ― 52, women ― 68), who were divided into the control and main groups. In the control group, treatment was carried out according to the traditional scheme of drug therapy, in the main ― according to the method of complex therapy. The treatment regimen according to this technique included the use of periodontal dressings and an antibacterial photodynamic therapy system: photosynthesis was applied to the affected area of the periodontal pocket, after which the pathogenic microorganisms were stained for 1-3 minutes, then the liquid was thoroughly washed from the periodontal pockets and the laser affected the affected area for 60 seconds. Results. The proposed treatment regimen using an antibacterial photodynamic system in combination with periodontal dressings allows to achieve a pronounced and prolonged anti-inflammatory effect in periodontal tissues without local and systemic use of antibiotics, reduces treatment time for mild periodontitis by 29, average ― by 57 %, reduces the likelihood recurrence, lengthens the duration of remission. Findings. The use of complex treatment of periodontitis of mild to moderate severity allows the method to accelerate the restoration of periodontal tissues, relieve inflammation, saturate the tissues with oxygen, reduce the rate of relapse by 2.6 times and reduce the duration of relapse of this disease within 24 months. Our data allow us to implement this treatment regimen in practical healthcare.


2021 ◽  
Vol 1 (38) ◽  
pp. 58-60
Author(s):  
A. V. Ivaschenko ◽  
A. E. Yablokov ◽  
I. N. Kolganov ◽  
M. V. Shcherbakov ◽  
I. V. Bazhutova ◽  
...  

Relevance. Before starting the therapeutic treatment of various periodontal diseases, it should be clearly understood that a high-quality treatment is possible only with complex therapy, excluding local irritating adverse factors in the oral cavity, elimination of inflammatory processes in the periodontal tissues, as well as violations of its function. One of the main tasks of the treatment of periodontal diseases is the preservation of the dentition with a single functional system.Purpose – to assess the use of the drug Kollapan in tooth extraction and treatment of periodontitis.Materials and methods. The clinical observation group consisted of 40 patients aged 19 to 65 years. The gender ratio was 3 : 2 (60% men, 40% women). The largest percentage of patients (65%) came to the clinic with complex tooth extraction. The remaining 35% – with generalized periodontitis of moderate and mild severity.Results. Clinical observation showed that in the first group of patients, whose therapy included the use of Collapan, after a complex tooth extraction, physiological healing of the hole was observed, the disappearance of inflammation within 24–36 hours after the surgery


Author(s):  
Sultanshina A.R. ◽  
Kabirova M.F. ◽  
Bashirova T.V.

With diabetes, there is a violation of the microvasculature, a violation of the immune status, an increase in destructive processes in the bone tissue, which leads to the development and / or intensification of pathological processes. In the oral cavity, the most frequently diagnosed inflammatory periodontal diseases, chronic injuries of the oral mucosa (COP), recurrent aphthous stomatitis, COP candidiasis. The aim of our study was to study the dental status of patients with type 2 diabetes mellitus. Materials and Methods: A descriptive evaluative epidemiologically controlled, non-randomized study was conducted to determine the effect of type 2 diabetes on dental status. The main group (“case”) consisted of 68 patients with type 2 diabetes in the compensation phase (IA) and 56 patients in the subcompensation phase (IB). The comparison group included 60 patients without somatic pathology. All patients underwent a comprehensive dental examination, bacteriological and microscopic examination to identify fungi of the genus Candida. Results: in patients with subcompensated form of type 2 diabetes, there was an increase in the frequency of complaints of plaque on the tongue, burning sensation in the COP, dryness and changes in taste. Periodontal indices indicate that the patients of the main group have a high prevalence of inflammatory and destructive processes in the periodontal tissues (indices of PMA, KPI, Mullemann indices) with poor oral hygiene (OHI-S = 3.5 ± 0.4), which confirms the Friedman criterion (χ2 = 116.27; p = 0.0000) based on the calculation of Kendall's concordance coefficient (0.743). The diagnosis of oral mucosa candidiasis was confirmed in 74.6% of patients in the main group by bacteriological examination.


2020 ◽  
Vol 73 (3) ◽  
pp. 517-520
Author(s):  
Anastasia I. Furdychko ◽  
Marta P. Ilchyshyn ◽  
Irena R. Fedun ◽  
Adriana Ya. Barylyak ◽  
Oksana M. Slaba ◽  
...  

The aim: To study the effect of drug addiction and smoking on the status of periodontal tissues in patients with hepatobiliary pathology. Materials and methods: 58 smokers, 63 drug addicts with hepatobiliary pathology were examined and 92 persons of comparison group (with inflammatory periodontal diseases affected by hepatobiliary pathology, without addiction). Examination of patients included determination of iodine number by Svrakov, S-L and Stallard hygiene indices, PMA index and index PBI. Results: The results of examination of smokers are worse in patients with cirrhosis than in patients with chronic toxic hepatitis and non-alcoholic steatohepatitis and also the results of these two groups was significantly worse than that of the comparison group (iodine number by Svrakov – 1,4 times and 1,3 times higher, PMA index – 1,7 times and 1,4 times worse, in accordance). The results of the study showed that drug addicts patients are worse values in patients with cirrhosis than in patients with chronic toxic hepatitis and non-alcoholic steatohepatitis and also the results of these two groups was significantly worse than that of the comparison group (iodine number by Svrakov – 1,5 times and 1,4 times higher, PMA index – 1,7 times and 1,5 times worse, in accordance). Conclusions: Presence of hepatobiliary pathology in smokers and drug addicts increases the risk of periodontal diseases.


2021 ◽  
Vol 106 (2) ◽  
pp. 28-35
Author(s):  
V. Batig ◽  
◽  
O. Tokar ◽  
I. Burdenyuk ◽  
◽  
...  

Goal. Improving the scheme of treatment and prevention of periodontal diseases in workers of the woodworking industry of Chernivtsi region, who in the process of professional activity have long-term contact with unfavorable factors of the production environment. Materials and methods. 70 workers of the woodworking industry with diagnosed chronic generalized periodontitis of the I degree were treated (35 people – the main group (A); 35 people – comparison group (B)), age – from 25 to 45 years. To compare the results of laboratory studies, an additional survey of 25 healthy individuals of the same age with an intact periodontium were conducted. They formed the control group (C). Clinical examination of patients was performed according to standart methods: subjective (complaints, medical history, life history) and objective (examination, periodontal indices, determination of the level of gingival attachment). Laboratory methods of research included determination of urease and lysozyme activity in saliva, degree of dysbiosis of oral cavity. As maintenance therapy, patients of the main group were prescribed the proposed composition DEPE. Results. After the treatment, a significant improvement in the hygienic status of patients in both groups was observed, but difference between groups A and B in the indicators of oral hygiene after treatment was no statistically significant (pA2–B2 > 0.05). There was a significant improvement in periodontal indices after treatment in patients of both groups (PMA index according to C. Parma, bleeding index according to Muhlemann in Cowell I. modification, Russell periodontal index, PSR-test), but the indicators in patients of the main group were significantly better – pA2–B2 < 0.05. In patients of the main group (A) the level of attachment loss decreased by 1.83 times, comparison group (B) – by 1.71 times. The difference in levels of attachment loss after treatment between groups A and B is statistically significant (pA2–B2 < 0.05). The activity of the enzyme urease in patients of the main group (A) and comparison group (B) after treatment was significantly reduced (pA1–A2 < 0.001, pB1–B2 < 0.001), but only in the main group it reached the level in the control group (C) (pA2–C > 0.05). The level of lysozyme after treatment was significantly increased in patients of both observation groups (pA1–A2 < 0.001, pB1–B2 < 0.001), and reached the level of lysozyme in patients of the control group (C) (pA2–C > 0.05, pB2–C > 0.05). The degree of oral dysbiosis in patients of the main group (A) was significantly reduced by 5.43 times (pA1–A2 < 0.001), and its difference from the degree of dysbiosis in patients of the control group (C) is statistically insignificant (pA2–C > 0.05 ). The degree of oral dysbiosis in patients of the comparison group (B) was significantly reduced by 3.04 times (pB1–B2 < 0.001), but still remained significantly different from oral dysbiosis in patients of the control group (C) (pB2–C < 0.05). Conclusion. The proposed pharmacological composition DEPE is an effective antiseptic solution and can be used in the phase of maintenance therapy to improve the treatment and prevention of periodontal disease in workers of woodworking industry. Key words: decamethoxine, propolis, ethonium, generalized periodontitis, woodworking industry.


2019 ◽  
Vol 26 (1) ◽  
pp. 40-48
Author(s):  
M. I. Shved ◽  
O. A. Prokopovych

The aim – to improve the existing therapeutic programs for patients with myocardial infarction (MI) by differentiated approach to therapy depending on the presence or absence of liver dysfunction. Materials and methods. 149 patients with acute MI were included to the study – 114 (76.5 %) men and 35 (23.5 %) women of average age 59.9±1.0 years. A comparative clinical-laboratory and instrumental examination was performed in these groups: 107 patients with MI with functional liver disorders (main group) and 42 patients with MI without functional liver disorders (comparison group). For the study of intracardiac hemodynamics, echocardiography was performed in B-mode. 52 patients of main group and 22 patients of comparison group received standard treatment for MI (ACE-inhibitors, β-blockers, clopidogrel and acetylsalicylic acid, anticoagulant therapy, statins). The other 55 patients of main group and 20 patients of comparison group received modified treatment with the addition of the antioxidant bioflavonoid – quercetin to the standard scheme. Results and discussion. In the initial condition of patients of main group there are more pronounced violations of central and peripheral hemodynamics which cause the disorders of protein synthesis, detoxification, energetic dysfunction of liver and lipid metabolism. At the same time there is an excessive activation of lipid peroxidation, suppressed activity of enzymes of the antioxidant protection system, deepening of pathological processes in the heart and in the liver. Inclusion of bioflavonoid quercetin to the complex therapy of patients with myocardial infarction provided the improvement of hemodynamic parameters – increased EF by 22.89 % and elimination of diastolic dysfunction, which were accompanied by normalization of clinical and laboratory parameters of liver function disorders – normalization of levels of bilirubin and ALT, GGT, ALP on 14-th day and reduction of LDL-level by 25.61 % after 3 weeks was marked. Conclusions. Introduction of bioflavonoid quercetin to the complex therapy of patients with MI provided improvement of hemodynamic parameters and restoration of oxidation-reduction equilibrium, reduction of clinical and laboratory manifestations of liver dysfunction and contributed to a significant decrease in the frequency of MI complications development. Restoration of parameters of cardiac hemodynamics, metabolic processes and liver functions provides a significant reduction in the rate of development of acute heart failure by 63.9 %, early post-infarction angina by 22.2 %, rhythm and conduction disorders by 43.6 %.


Author(s):  
O. V. Shvets ◽  
Tatiana V. Gaivoronskaya ◽  
E. E. Esaulenko ◽  
N. I. Bykova

Aim. This study aims to increase the efficiency of the wound process in patients with odontogenic phlegmons of the maxillofacial region by using energotropic and antioxidant agents. Material and methods. The clinical study included 42 patients with odontogenic phlegmons of the maxillofacial region. The patients were divided into two groups: comparison group (patients received traditional treatment) and main group (patients received treatment with Cytoflavin in the treatment regimen). Results. In the main group, the appearance of the first granulations occurred 2.1 times faster (on average on the 3rd day) in comparison with the granulation tissue in patients of the comparison group. Signs of edge epithelialization of wounds appeared almost 3 days earlier (on average on the 6th day) in the main group than in the comparison group; on the 7th day, secondary sutures were already applied, which was 1.6 times faster than the same parameter group 2, clearly suggesting the acceleration of reparative processes. Conclusion. The dynamics of clinical manifestations indicates the comparative effectiveness of using Cytoflavin as part of complex therapy. This finding is confirmed by the accelerated terms of wound healing, the appearance of granulations, epithelialization of the wound edges, and the imposition of secondary sutures.


Author(s):  
T.V. Budina ◽  
E.G. Margaryan ◽  
A.G. Ovsienko

Systemic diseases of the body, including obstructive sleep apnea (OSA), play an essential role in the pathogenesis of chronic generalized periodontitis. The main dental symptom of OSA is dry mouth due to oral breathing, which is a significant risk factor for periodontal disease. Purpose. Сlinical and laboratory assessment of periodontal tissues in patients with obstructive sleep apnea. Material and methods. The subjects of our study were patients from 35 to 65 years old. In total, 40 patients with obstructive sleep apnea syndrome and 30 patients who made up the comparison group were examined. Patients with obstructive sleep apnea syndrome were divided into three groups according to the severity of apnea. The first group included patients of women and men with mild apnea, the second group of men and women with moderate apnea, and the third with severe obstructive sleep apnea. Gum bleeding was assessed by the Mulleman-Cowell index, the degree of inflammation in the gum using the papillary-marginal-alveolar index (PMA). The hygiene index was evaluated by Quigle-Hein as modified by Tureski. Results. The hygienic condition of the oral cavity in patients with obstructive sleep apnea was rated as “unsatisfactory”. In the structure of the distribution of periodontal diseases in patients with obstructive sleep apnea, periodontitis of moderate severity prevails, while in the comparison group - periodontitis of mild severity. We also observed a correlation between the severity of apnea and the values of periodontal indices. Index data for mild severity and the data of the comparison group practically did not differ. While in severe apnea, the indices were much higher (average Muhlemann-Cowell index — 1.59±0.3, РМА — 57.49±0.87%) than the comparison group (average Muhlemann-Cowell index — 1.25±0.1, РМА — 38.84±0.93%). When assessing the qualitative composition of the oral microflora by PCR of patients with apnea, a higher number of P. gingivalis and A. Actinomycetemcomitans was revealed compared with the comparison group (p <0.02). Conclusions. According to the results of the dental examination, the prevalence of inflammatory periodontal diseases in patients with obstructive sleep apnea is higher than in the comparison group. The data obtained indicate a more severe periodontal disease in patients with obstructive sleep apnea compared with the comparison group.


2021 ◽  
Vol 38 (6) ◽  
pp. 83-93
Author(s):  
N. B. Astashina ◽  
E. P. Rogozhnikova ◽  
A. S. Arutyunov ◽  
N. N. Malginov ◽  
S. V. Kazakov

Relevance. The relevance of the study is dictated by the high prevalence of periodontal disease among young people and by the need to search for new approaches to periodontitis treatment in order to increase the effectiveness of treatment at early stages of pathological process. Objective. To evaluate the effectiveness of complex treatment of chronic generalized periodontitis (CGP) of mild severity using a removable splinting construction made according to the author's technique. Materials and methods. At the orthopedic stage of the complex treatment of mild CGP, splinting constructions were used for 47 young patients: in the main group (n = 16) the authors treatment and preventive splint, in the first comparison group (n = 15) a removable metal splint, in the second comparison group (n = 16) a fixed adhesive fiber splint. Periodontal hemodynamics was assessed using ultrasound Doppler analysis 1, 6 and 12 months after the therapeutic measures and tooth immobilization. To identify the possible negative impact of the treatment on the quality of life (QOL) in patients with splint constructions, we used the OHIP-14-Ru questionnaire; the follow-up period was 1.3, 6, and 12 months. Results. Dental immobilization contributed to the improvement of blood flow in the periodontal tissues in the short and long term follow-up, so after 12 months: Vam in the main group increased by 39,8 % and amounted to 0,397 0,004 cm / s, in patients of the comparison groups Vam was 0,329 0,006 cm / s and 0,335 0,003 cm / s, respectively, that is 15,4 % and 18,4 % higher compared with the figures before treatment. The quality of life index for patients using splinting constructions made according to the author's technique, by the OHIP-14-Ru questionnaire was assessed as good 1 year after (3.46 0.59). Conclusions. The use of the proposed original orthopedic design in a complex plan for mild periodontitis treatment helps to improve regional blood circulation and stabilize the pathological process.


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