scholarly journals The Association of Socio-Economic Factors, and Smoking Behavior With COPD Severity in an Industrial City of Iran

2021 ◽  
Author(s):  
Mohammadali Zohal ◽  
Sima Rafiei ◽  
Neda Esmailzadehha ◽  
Sanaz Jamshidi ◽  
Nafiseh Rastgoo
Keyword(s):  
Smoking Status ◽  
Care Center ◽  
Smoking Behavior ◽  
Chronic Obstructive Lung Disease ◽  
Respiratory Function Tests ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Factors Associated ◽  
Copd Patients ◽  
Wide Range

Socioeconomic and lifestyle factors are regarded as important influencing issues regarding a wide range of chronic diseases, including chronic obstructive pulmonary disease. This study aimed to explore the role of such factors as determinants of disease exacerbation among COPD patients. A cross-sectional study was conducted among 150 COPD patients who were referred to an outpatient respiratory care center in Qazvin, Iran, to undertake respiratory function tests from December 2017 to June 2018. Disease severity was determined by the Initiative for Chronic Obstructive Lung Disease (GOLD) index. Odds ratios were applied to find out factors associated with exacerbation. Study findings affirmed that within COPD severity groups, there were significant differences among patients in terms of educational level, smoking status, income, and occupation. Factors associated with severe COPD were found to be smoking (OR 3.6, 2.6-4.2), lower education (OR 1.4, 0.9-2.6), insufficient income (OR 2.3, 0.6-3.1), and unsupportive family (2.7, 1.5-3.6). Due to the obtained evidence about the effect of socioeconomic status on the prognosis of the disease, it is suggested that clinicians should also consider the nonclinical and social aspects associated with the disease in advancing patients' therapeutic procedures and management algorithms.

scholarly journals Sarcopenia in COPD: relationship with COPD severity and prognosis

2015 ◽  
Vol 41 (5) ◽  
pp. 415-421 ◽  
Author(s):  
Tatiana Munhoz da Rocha Lemos Costa ◽  
Fabio Marcelo Costa ◽  
Carolina Aguiar Moreira ◽  
Leda Maria Rabelo ◽  
César Luiz Boguszewski ◽  
...  
Keyword(s):  
Lean Mass ◽  
Smoking Status ◽  
Airflow Obstruction ◽  
Chronic Obstructive Lung Disease ◽  
The Body ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Skeletal Muscle Index ◽  
Gold Stage ◽  
Copd Patients

Objective: To evaluate the prevalence of sarcopenia in COPD patients, as well as to determine whether sarcopenia correlates with the severity and prognosis of COPD. Methods: A cross-sectional study with COPD patients followed at the pulmonary outpatient clinic of our institution. The patients underwent dual-energy X-ray absorptiometry. The diagnosis of sarcopenia was made on the basis of the skeletal muscle index, defined as appendicular lean mass/height2 only for low-weight subjects and adjusted for fat mass in normal/overweight subjects. Disease severity (COPD stage) was evaluated with the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. The degree of obstruction and prognosis were determined by the Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity (BODE) index. Results: We recruited 91 patients (50 females), with a mean age of 67.4 ± 8.7 years and a mean BMI of 25.8 ± 6.1 kg/m2. Sarcopenia was observed in 36 (39.6%) of the patients, with no differences related to gender, age, or smoking status. Sarcopenia was not associated with the GOLD stage or with FEV1 (used as an indicator of the degree of obstruction). The BMI, percentage of body fat, and total lean mass were lower in the patients with sarcopenia than in those without (p < 0.001). Sarcopenia was more prevalent among the patients in BODE quartile 3 or 4 than among those in BODE quartile 1 or 2 (p = 0.009). The multivariate analysis showed that the BODE quartile was significantly associated with sarcopenia, regardless of age, gender, smoking status, and GOLD stage. Conclusions: In COPD patients, sarcopenia appears to be associated with unfavorable changes in body composition and with a poor prognosis.

scholarly journals Classification of COPD patients and compliance to recommended treatment in Greece according to GOLD 2017 report: the RELICO study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Nikolaos Tzanakis ◽  
Nikolaos Koulouris ◽  
Katerina Dimakou ◽  
Konstantinos Gourgoulianis ◽  
Epameinondas Kosmas ◽  
...  
Keyword(s):  
Chronic Obstructive Lung Disease ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Medical Practitioners ◽  
Recommended Treatment ◽  
Copd Patients ◽  
Assessment Approach ◽  
Impaired Lung Function ◽  
Group B

Abstract Background Chronic obstructive pulmonary disease (COPD) is a multifactorial clinical condition, characterized by chronic progressive (or worsening) respiratory symptoms, structural pulmonary abnormalities, and impaired lung function, and is often accompanied by multiple, clinically significant comorbid disorders. In 2017, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) issued a new report on COPD prevention, diagnosis and management, aiming at personalizing the maintenance therapeutic approach of the stable disease, based on the patients’ symptoms and history of exacerbations (ABCD assessment approach). Our objective was to evaluate the implementation of GOLD suggestions in everyday clinical practice in Greece. Methods This was a cross-sectional observational study. Sixty-five different variables (demographics, vital sign measurements, COPD-related medical history parameters, comorbidities, vaccination data, COPD severity based on spirometry measurements, COPD stage based on the ABCD assessment approach, COPD treatments) were collected from 3615 nation-wide COPD patients (Greece). Results The mean age at the time of initial COPD diagnosis was 63.8 (± 10.2). Almost 60% of the subjects were classified into group B, while the remaining patients were falling into groups A (18%) and D (21%), and only a small minority of patients belonged to Group C, according to the ABCD assessment approach. The compliance of respiratory physicians to the GOLD 2017 therapeutic suggestions is problematic, especially when it comes to COPD patients belonging to Group A. Conclusion Our data provide valuable information regarding the demographic and medical profile of COPD patients in Greece, the domains which the revised ABCD assessment approach may show some clinical significance on, and the necessity for medical practitioners dealing with COPD patients to adhere closer to international recommendations for the proper management of the disease.

scholarly journals Study of Factors Associated with Sarcopenia in COPD Patients

2021 ◽  
Vol 33 (1) ◽  
pp. 50-53
Author(s):  
Saleh Ahmed
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Bioelectrical Impedance ◽  
Chronic Obstructive ◽  
College Hospital ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Factors Associated ◽  
Copd Patients ◽  
Severe Copd

Introduction: Sarcopenia is frequently associated with chronic diseases such as chronic obstructive pulmonary disease (COPD). Sarcopenia can be classified as physical frailty where frailty is associated with adverse health outcomes. Sarcopenia was found to be associated with worsening lung function in male COPD patient. Objective was to find out the factors associated with sarcopenia in COPD patients. Materials & Methods: This was cross-sectional observational study was carried out Different Privet Medical in Chandpur and Chandpur Medical College Hospital, Chandpur. Patients diagnosed with COPD according to Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) guidelines were included in this study. Exclusion criteria were unstable cardiac disease, an exacerbation within the preceding 4 weeks, predominant neurological limitation to walking (eg, significant hemiplegia) or contraindication to bioelectrical impedance analysis (BIA) including an implanted pacemaker or defibrillator. All participants gave written informed consent. EWGSOP criteria were applied to outpatients with stable COPD. Results: In uniavariate analysis, age, moderate COPD, severe COPD, obesity, non-elective admission over the past 12 months, MMRC scale and MAP were significantly associated with sarcopenia. In multivariate analysis, age, moderate COPD, severe COPD, obesity and MMRC scale were significantly associated with sarcopenia. Conclusion: Prevalence of sarcopenia was 26%. Independent factors associated with sarcopenia Age (>70 years) years (adjusted odds ratio (AOR) 4.387. Sarcopenia affects about one-quarter of COPD patients. Age, severity of COPD, MMRC scale, and BMI status were the factors associated with sarcopenia. Medicine Today 2021 Vol.33(1): 50-53

scholarly journals Daily Activity Related Quality of Life in Chronic Obstructive Pulmonary Disease in Adults

2019 ◽  
Vol 3 (1) ◽  
pp. 10-23
Author(s):  
Ruhamah Yousaf ◽  
Muhammad Arif ◽  
Qudrat Ullah ◽  
Saima Rafique ◽  
Asif Hanif ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Daily Activity ◽  
Smoking Status ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients

Abstract: Background: The significant reason for anguish as well as incapacity is chronic obstructive pulmonary disease (COPD). Activities of daily living might be relentlessly curbed among patients with COPD and appraisal needs evaluation regarding influence of infirmity and detriments on day-to-day living. The primary objective was to know the daily activity associated quality of life in COPD adults. The secondary objective was to analyze demographical profile, such as gender and age of COPD subjects as well as evaluate the physical activity related breathlessness in COPD patients. Methodology: This study was executed at Gulab Devi Chest Hospital. We used cross sectional study design to collect the data. For collecting the statistics of 150 subjects aged 40-60 years of either gender Saint George’s Questionnaire was liable. It included the patient’s biodata, effect of COPD on physical activities and limitations in routine work. Results: The ages of 150 COPD patients selected were between 40 and 60 years. Patients were classified into two categories on the basis of disease severity according to GOLD criteria 71 (47.3%) were with moderate severity and 79 (52.7%) were with severe severity. 113 (75.3%) patients were smokers while 37 (24.7%) patients were non-smokers. 110 (73.3%) COPD patients were active smokers in comparison 40 (26.7%) COPD patients were passive smokers. COPD patients with current smoking status were 79 (52.7%) and with past smoking status were 71 (47.3%). 19 (12.7%) COPD patients felt breathlessness while sitting and lying. 53(35.3%) COPD patients felt breathless while getting washed or dressed. 85(56.7%) COPD patients felt breathless while walking around the home. 114 (96%) COPD patients discerned breathlessness while walking up a flight of stairs. 145 (96.7%) COPD patients had breathlessness while playing sports or games. 146 (97.3%) COPD patients experienced difficulty in breathing during activities like carrying load. 88 (58.7%) COPD patients discerned breathlessness during entertainment or recreation. 88 (58.7%) COPD patients discerned breathlessness during entertainment or recreation. 7 (4.7%) COPD patients felt breathlessness while moving from bed or chair. Conclusion: As with the progression of COPD impairment in activities become worse due to breathlessness causing decline in patient’s ability making them unable to complete their task to fulfill the needs of life and ultimately become bed bound due to shortness of breath.

scholarly journals The Influence of Smoking Status on Exhaled Breath Profiles in Asthma and COPD Patients

Molecules ◽  
2021 ◽  
Vol 26 (5) ◽  
pp. 1357
Author(s):  
Stefania Principe ◽  
Job J.M.H. van Bragt ◽  
Cristina Longo ◽  
Rianne de Vries ◽  
Peter J. Sterk ◽  
...  
Keyword(s):  
Smoking Status ◽  
Characteristic Curve ◽  
Cigarette Consumption ◽  
Chronic Obstructive ◽  
Exhaled Breath ◽  
Healthy Controls ◽  
Cross Sectional ◽  
Linear Discriminant ◽  
Copd Patients ◽  
Never Smokers

Breath analysis using eNose technology can be used to discriminate between asthma and COPD patients, but it remains unclear whether results are influenced by smoking status. We aim to study whether eNose can discriminate between ever- vs. never-smokers and smoking <24 vs. >24 h before the exhaled breath, and if smoking can be considered a confounder that influences eNose results. We performed a cross-sectional analysis in adults with asthma or chronic obstructive pulmonary disease (COPD), and healthy controls. Ever-smokers were defined as patients with current or past smoking habits. eNose measurements were performed by using the SpiroNose. The principal component (PC) described the eNose signals, and linear discriminant analysis determined if PCs classified ever-smokers vs. never-smokers and smoking <24 vs. >24 h. The area under the receiver–operator characteristic curve (AUC) assessed the accuracy of the models. We selected 593 ever-smokers (167 smoked <24 h before measurement) and 303 never-smokers and measured the exhaled breath profiles of discriminated ever- and never-smokers (AUC: 0.74; 95% CI: 0.66–0.81), and no cigarette consumption <24h (AUC 0.54, 95% CI: 0.43–0.65). In healthy controls, the eNose did not discriminate between ever or never-smokers (AUC 0.54; 95% CI: 0.49–0.60) and recent cigarette consumption (AUC 0.60; 95% CI: 0.50–0.69). The eNose could distinguish between ever and never-smokers in asthma and COPD patients, but not recent smokers. Recent smoking is not a confounding factor of eNose breath profiles.

scholarly journals Sarcopenia in chronic obstructive pulmonary disease: A study of prevalence and associated factors in the Southeast Asian population

2017 ◽  
Vol 15 (3) ◽  
pp. 250-257 ◽  
Author(s):  
Panita Limpawattana ◽  
Pratchaya Inthasuwan ◽  
Siraphong Putraveephong ◽  
Watchara Boonsawat ◽  
Daris Theerakulpisut ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Handgrip Strength ◽  
Systemic Disease ◽  
Adverse Outcomes ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Factors Associated ◽  
Copd Patients

Chronic obstructive pulmonary disease (COPD) has been described as a systemic disease. Sarcopenia is one of the systemic effects that is related to several adverse outcomes. The objectives of this study were to estimate the prevalence of sarcopenia and to determine the factors associated with sarcopenia in COPD patients in Southeast Asia. This was a cross-sectional study of COPD patients who attended a COPD clinic from May 2015 to December 2016. Baseline characteristics were collected and dual-energy X-ray absorptiometry was used to measure skeletal muscle mass. Handgrip strength was used to assess muscle strength, and as a measurement of physical performance, the 6-min walk distance was used. One hundred and twenty-one participants were recruited. Most of them were men (92.6%). Prevalence of sarcopenia was 24% (29 cases). Independent factors associated with sarcopenia were age ≥ 75 years (adjusted odds ratio (AOR) 13.3, severity of COPD (AOR 19.2 and 13.4 for moderate and severe COPD), Modified Medical Research Council (MMRC) scale (AOD 1.9), and obesity (AOR 0.04). Sarcopenia affects about one-quarter of COPD patients. Age, severity of COPD, MMRC scale, and BMI status were the factors associated with sarcopenia.

scholarly journals Faktor-Faktor yang Mempengaruhi Kualitas Hidup Pasien Penyakit Paru Obstruksi Kronis (PPOK)

2018 ◽  
Vol 34 (2) ◽  
pp. 62
Author(s):  
Putri Tiara Rosha ◽  
Fatwa Sari Tetra Dewi
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Smoking Status ◽  
Medication Management ◽  
Current Smoker ◽  
Normal Weight ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Factors Associated

Factors associated with quality of life among patients with chronic obstructive pulmonary diseasePurposeThis study is conducted to examine factors associated with quality of life among patients with the chronic obstructive pulmonary disease.MethodsThis study was a cross-sectional study involving 146 patients from Muhammadiyah and Temanggung hospital. The quality of life was measured using clinical questionnaire. The independent variables were body mass index, smoking status, severity level, hypertension, diabetes mellitus, and depression. Data were analyzed using Chi-Square and Poisson regression.ResultsThe majority of patients aged 67 years (36.3%) are male (61%), had normal weight (55.5%) and quitted smoking for 0-5 years (20.6%). Spirometry shows that almost half (40,4%) patients are at the moderate level. The highest proportion of comorbidities are hypertension (34.2%), depression (32.9%) and diabetes mellitus (6.2%). There are 28.1% patients who had a poor quality of life. Multivariate analysis shows that current smoker, very severe level of the disease and depression related to the quality of life.ConclusionCurrent smoker, very severe level of the disease and depression could lead to a worse quality of life. Medication management programs should encourage patients to stop smoking. The development of interventions focusing on depression is also needed.

scholarly journals Prevalence and risk factors for COPD in farmers: a cross-sectional controlled study

2015 ◽  
Vol 47 (1) ◽  
pp. 95-103 ◽  
Author(s):  
Alicia Guillien ◽  
Marc Puyraveau ◽  
Thibaud Soumagne ◽  
Stéphanie Guillot ◽  
Fabrice Rannou ◽  
...  
Keyword(s):  
Smoking Status ◽  
Chronic Obstructive Lung Disease ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Controlled Study ◽  
Chronic Obstructive ◽  
Tobacco Exposure ◽  
Cross Sectional ◽  
Obstructive Pulmonary Disease ◽  
Cattle Breeders

There are conflicting data regarding the magnitude and determinants of chronic obstructive pulmonary disease (COPD) risk in farmers.In a cross-sectional study of 917 nonfarming working controls and 3787 farmers aged 40–75 years, we assessed respiratory symptoms, tobacco exposure, job history (without direct exposure measurement) and lung function. COPD was defined by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criterion (post-bronchodilator forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) <0.70) and by the Quanjer reference equation (post-bronchodilator FEV1/FVC <lower limit of normal (LLN)).The prevalence (95% CI) of COPD according to the GOLD criterion was 5.1% (4.4–5.8%) and 2.9% (1.8–4.0%) in farmers and controls, respectively (p=0.005), and 3.1% (2.5–3.6%) and 1.5% (0.7–2.3%), respectively, for the LLN criterion (p<0.01). For both COPD criteria after adjustment for age, sex and smoking status, COPD prevalence was similar in controls and crop farmers. Compared to controls, four job categories had a higher prevalence of COPD according to the GOLD criterion, namely, cattle breeders, swine breeders, poultry breeders and breeders of two or more livestock types. Among cattle breeders, only those from Franche-Comté had higher prevalence of COPD according to both GOLD and LLN criteria.The prevalence of COPD in farmers is higher than in nonfarming working controls, and depends on the farming activity, the region and the criterion used to define COPD.

scholarly journals COPD, metabolic syndrome, respiratory symptoms, and functional incapacity in smokers, ex-smokers, and never-smokers aged 40-59 in Almaty, Kazakhstan: a cross-sectional study

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 688
Author(s):  
Baurzhan Zhussupov ◽  
Almaz Sharman ◽  
Dana Sharman
Keyword(s):  
Metabolic Syndrome ◽  
Respiratory Symptoms ◽  
Smoking Status ◽  
Smoking Behavior ◽  
Cross Sectional Study ◽  
Chronic Obstructive ◽  
Sectional Study ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
Never Smokers

Background: No study has reported the relationship between smoking status with chronic obstructive pulmonary diseases (COPD) and metabolic syndrome (MetS) in Kazakhstan. The aim of this study was to assess the associations between health outcomes, including COPD, MetS, respiratory symptoms, and functional incapacity, with the cigarette smoking status. Methods: The cross-sectional study recruited 500 smokers, 200 ex-smokers, and 200 never-smokers aged 40-59 in Almaty, Kazakhstan. Questions assessed socio-demographic, clinical characteristics, and smoking behavior. Blood glucose and lipid profiles were determined after overnight fasting. COPD was defined according to the GOLD 2017 statement. Respiratory symptoms and functional incapacity were assessed by the COPD Assessment Test (CAT) and 6-min walk test (6MWT), respectively. Logistic regression models were used to assess the associations. Results: The prevalence of COPD among smokers, ex-smokers and never-smokers were 5.5%, 3.0% and 3.0%, respectively. Respiratory symptoms based on CAT were more prevalent among smokers (42.8%) as compared to ex-smokers (42.8% vs 17.0%; aOR 3.43, 95% CI 2.25–5.23) and never-smokers (42.8% vs 12.5%; aOR 5.44, 95% CI 3.42–8.65). Current smokers were more likely to walk less than 450 meters during 6MWT as compared to never-smokers (16.5% vs 5.0%; aOR 3.72, 95% CI 1.86–7.44). No significant association was found between the smoking status with COPD and MetS.  Conclusions: Respiratory symptoms are common among the current smokers, even if most of them had preserved pulmonary function defined by spirometry.

scholarly journals The Prevalence of Diabetes Mellitus in COPD Patients with Severe and Very Severe Stage of the Disease

2016 ◽  
Vol 4 (2) ◽  
pp. 253-258 ◽  
Author(s):  
Jagoda Stojkovikj ◽  
Beti Zafirova-Ivanovska ◽  
Biserka Kaeva ◽  
Sasha Anastasova ◽  
Irena Angelovska ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Smoking Status ◽  
Severe Disease ◽  
Chronic Obstructive ◽  
Cross Sectional ◽  
Severe Stage ◽  
Copd Patients ◽  
Severe Group ◽  
Prevalence Of Diabetes Mellitus ◽  
Severe Copd

AIM: The aim of the study was to investigate the prevalence of diabetes mellitus in privies diagnosed chronic obstructive pulmonary disease (COPD) patients with severe and very severe disease, which ware stable.METHODS: We investigated 100 subjects, all of them smokers, with smoking status >10 years. They were stratified in two groups. It was clinical, randomized, cross sectional study. Besides demographic parameters, functional parameters, BMI, cholesterol, LDL and HDL, and the level of blood sugar was measured. RESULTS: The prevalence of diabetes mellitus in our survey in total number of COPD patients with severe and very severe stage was 21%. In the very severe group were recorded significantly higher average values of glycaemia compared with severe group (7.67 ± 3.7 vs. 5.62 ± 0.9, p = 0.018). In the group with severe COPD, it was not confirmed any factor with significant predictive effect on the values of glycaemia. As independent significant factors that affect blood glucose in a group of very severe COPD were confirmed cholesterol (p <0.0001) and HDL (p = 0.018). CONCLUSION: These results suggest that the presence of the COPD in patients itself is a factor that results in the clinical presentation of diabetes mellitus Type 2.

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