scholarly journals Vascular Disaggregated Platelet Control in Newborn Piglets

2021 ◽  
Author(s):  
Elena S. Tkacheva

The balance of platelet and vascular functions clearly determines the functioning of primary hemostasis in the piglet’s body. This is of particular physiological importance at the beginning of piglet ontogenesis. The degree of functional readiness of platelets and blood vessels in piglets during the neonatal period determines the state of blood microcirculation in tissues and the activity of many functional mechanisms at this stage of development. The activity of the disaggregation properties of blood vessels, which significantly determines the intensity of anabolism and, ultimately, the productivity of animals, is particularly important at this age. This study examined 31 healthy newborn piglets. A decrease in the amount of peroxidation products was found in the blood of all animals due to an increase in the antioxidant potential of their plasma, which created conditions in newborn piglets for weak alteration of the vascular endothelium and its optimal synthetic activity. This led to an increase in the vascular control over the platelet aggregation activity, maintaining the optimal blood flow in microvessels from the beginning of individual development. Keywords: piglets, neonatal phase, blood vessels, platelets, aggregation, lipid peroxidation

2020 ◽  
Vol 17 ◽  
pp. 00163
Author(s):  
Elena V. Krapivina ◽  
Andrei L. Kryazhev

The deployment of the first stages of ontogenesis in all types of productive animals is determined by the change in hemostatic and rheological mechanisms. The status of these parameters strongly influences the deployment of heredity of an organism of any animal. The normal operation of the hemostasis during the neonatal strongly determines the rheological properties of blood, and therefore metabolism in the organs of young animals. Phase of neonatal calves and piglets is a serious stage of their development. Therein have the characteristic of hemostatic processes. The authors determined that during the first or second day of life in physically impaired calves and piglets develop physiologically unfavorable changes in haemostatic parameters, platelets, blood vessels and blood clotting. Emerging changes adversely affect the operation of their bodies and lead to total exclusion. The use of the drug gamavit enhances the weakened condition of newborn calves and piglets functionally acceptable reduce the activity of platelets and clotting of blood in a functionally justified the growth of the hemostatic capabilities of the vessels. It can be argued that injections of gamavit negate the existing dysfunction in hemostasis in physically weakened calves and piglets during the neonatal phase, increasing their adaptation and stimulating further growth and development of animals.


2019 ◽  
Vol 4 (2) ◽  
pp. 57-68
Author(s):  
Zatul Haefa ◽  
Hamdana ◽  
Amirullah

Elderly is the final stage of development in the human life cycle. In the elderly there is an anatomic decline and function of the organs. Decreased function of blood vessels can cause hypertension. Hypertension or high blood pressure is a condition where when the blood pressure in the blood vessels increases, the measurement results are 140/90 mmHg. One that affects the reduction in hypertension without drugs is exercise that is not too heavy on a regular basis such as hypertension gymnastics. Hypertension or elderly exercise is a form of aerobic exercise that is beneficial for the elderly. Regular elderly exercise can help maintain blood pressure balance. The purpose of this study was to determine the effect of hypertension exercise on reducing blood pressure in the elderly in the work area of ​​the Bontonyeleng Health Center. The design of this study used a pre-experimental research design (One-group pre-post test design) obtained a sample of 30 people by using a sampling technique that is Nonprobability sampling with incidental sampling approach. The results of the normality test show that the data are not distributed so that they do not meet the paired T test and an alternative test is used is the Wilcoxon test. P value obtained is 0,000 (p <0.05) on systolic and diastolic blood pressure, so Ho is rejected and Ha is accepted. It can be concluded that there is an effect of hypertension gymnastics on the decrease in systolic and diastolic blood pressure in the elderly in the work area of ​​the Bontonyeleng Health Center. And it is advisable to have information about hypertension and further increase the frequency of exercise in the elderly at least 2-3 times a week to get better results.


Author(s):  
Margaret H. Sanderson ◽  
S. Phyllis Steamer

The chick embryo exposed to lethal doses of ionizing radiations develops a fatal circulatory failure within a few hours. This report describes the blood vessels of the area pellucida (a part of the extra-embryonic membranes of the chick embryo) and the effect of 250 kVp x-radiation upon them.Three-day chick embryos, x-irradiated in ovo with 1000-1200 R, were fixed 1-2 hours after exposure. The area pellucida is a multi-layered membrane consisting of ectoderm, somatic and splanchnic mesoderm, and endoderm (Fig. 1). The vascular system arises from the splanchnic mesoderm. The walls of small and medium-sized vessels are composed of endothelial cells, an occasional pericyte and processes of adjacent mesenchyme cells. Types of vessels cannot be distinguished at this stage of development; a basement membrane is seen only in isolated areas. The wall appears double or triple-layered, but the endothelium is frequently less than 0.1 micron thick (Fig. 2). Endothelial cells contain a large complement of polyribosomes, mitochondria, rough and smooth endoplasmic reticulum, a Golgi complex, pinocytotic vesicles and several kinds of inclusion bodies. The nucleus has a well-defined nucleolus.


2020 ◽  
Vol 17 ◽  
pp. 00166
Author(s):  
Elena S. Tkacheva

The important element in the functioning of hemostasis in the body of a piglet is platelet aggregation activity. The degree of its severity in piglets largely controls the functional state of primary hemostasis and the severity of microcirculation in their tissues, determining the formation of many functional mechanisms. The aggregation activity of platelets in early ontogenesis significantly determines the growth and development of the animal in the future and ultimately the level of its productivity. The examination of 36 healthy piglets of milk nutrition showed a decrease in the content of peroxidation products in their blood as a result of increased activity of their antioxidant potential in plasma. This led to their weak platelet alteration, contributing to their optimal aggregation activity. In piglets during the phase of milk feeding, a gradual increase in the aggregation properties of platelets is noted, regulating blood flow in vessels of the smallest caliber.


1930 ◽  
Vol 52 (1) ◽  
pp. 81-87 ◽  
Author(s):  
A. E. Cohn ◽  
Fritz Lange

On the basis of the anatomical studies presented the following inferences or conclusions are drawn. 1. In the course of development there appear in the vascular membranes of chick embryos arterial vessels of all calibers, namely, capillaries, small arteries with 2 or 3 cell layers, and large arteries formed of endothelium, longitudinal and circular layers of muscle and adventitia. 2. In none of the stages are elastic fibers developed. Only in the most central portion of the umbilical artery, in that portion namely which is to be regarded as belonging to the embryo, are elastic fibers discoverable. 3. The structure of capillaries is histologically the same at all stages. The small arteries of embryos 10 days old resemble histologically those of 18. At no stage of development are appearances of degeneration nor of fat to be found in arteries. When the physiological results of our investigations are compared with the anatomical ones the following comments may be made. In respect to Paragraph 1 of the anatomical results we may remark that when we study the different forms of the wall of arterial vessels the most delicate vessels consisting of single cells exhibit the greatest irritability. Those which are built of 3 to 4 muscle layers are less irritable. Stouter vessels appearing for the first time at 10 days of incubation require stronger stimuli to bring about the same reaction. In respect to Paragraph 2 of the anatomical results we may make this comment. The absence of elastic fibers in all arteries of the embryonic membranes throughout the period of their development is important in defining a physiological property of the larger vessels. The medium and larger vessels, beginning with the 4th day of incubation, contract differently from normal adult human arteries. In the contracted state they appear in cross section not as small replicas of larger circular structures, but take on a new form. During the course of contraction they become flat and appear band-like as would a garden hose when it is compressed by a weight. In examining a vessel so contracted one sees on rotating the vessel either a broad side or a narrow one. It is for this reason that such arteries appear alternately narrow as a line or broad as a band. It is not until the narrow artery is elevated with a hook that its uniform band-like nature becomes evident. The absence of elastic tissue, the presence of which in all probability is mainly responsible for the usual shape of arteries on cross section, permits one to see how the phenomenon which has been described may come about. Concerning Paragraph 3 of the anatomical conclusions we have this to say. According to the histological investigation a stage of degeneration is wanting in the blood vessels of the embryonic membrane in a sense in which one is accustomed to see such changes in other blood vessel systems during the course of life. On the day of hatching the constituent cells and fibers of the arteries of all calibers are anatomically the same as in their early development. These vessels do not die as the result of aging: The nutrient fluid ceases to flow because of contraction of the umbilical vessels. The blood vessels die in complete possession of their physiological irritability and anatomical integrity. The unaltered irritability of blood vessels of the same caliber at all ages is consonant with their unaltered anatomical structure.


Author(s):  
A. Yu. Perevaryukha

The article discusses the approach to modeling of metamorphoses in the development of a number of species in the context of their influence on the success of long-term trends of population dynamics. Changes in survival during early ontogenesis, controlled by important factor – the rate of individual development in a competing group of individuals, can cause unexpected degradation of population with a small excess fishing impact. The theory of nonlinear efficiency of reproduction leads us to the hypothesis that two different nonlinear effects are controlled by similar mechanisms. For insects such fluctuations in survival during metamorphosis can start another process - the rapid outbreak of pests, where actual formalization of the impact of parasites on the first stage of development, depending on the initial concentration of clutches, but limited resources is taken into account at a finishing. The method has been for submission to decline of generations on the basis of dynamic overriding differential equations with discrete-continuous structure of time. To extend the previously proposed model for the formation of generations is formed computing structure for the account mortality depending on the level of competition, complete with trigger functional and a new scheme describing the changes the growth rate for the example of the Caspian Sea sturgeon in three ecological and physiological stages of development. The new model has a non-trivial possibilities parametrically modification of behavior regimes. The coexistence of alternative cycles is explained by the increase in adaptive interspecies differences.


2018 ◽  
Vol 9 (2) ◽  
pp. 237-243 ◽  
Author(s):  
A. G. Lapirov ◽  
E. A. Belyakov ◽  
O. A. Lebedeva

Lobelia dortmanna L. is one of the few rare, slowly growing relic plants occupying areas of the littoral zone of water bodies with low nutrient content and subject to wave action. Even in such difficult conditions, this plant successfully passes its entire life cycle, actively blossoms and fruits. That is why the peculiar features of the individual development of this plant in various geographical conditions is a matter of great interest. For the first time, this study considers in detail the ontogeny of the genet of L. dortmanna in oligotrophic lakes of Tver oblast. Detailed characteristics of the following age stages of individuals are given: resting seeds, seedlings, juvenile, young and adult vegetative, latent generative, middle-aged and old generative and quasisenile plants. It is shown that the transition to the juvenile age stage occurs at the end of the first year of life, the virginile age stage lasts two years, and the generative stage of development occurs in the fourth year of life. The change in the growth pattern of the rosette main shoot of Lobelia, from orthotropic to anisotropic, occurs in the second year of life. The establishment and further development of the generative organs of the plant and associated change in the growth of the main shoot from monopodial to simpodial occurs in the fourth year of life. At the same time, the branching of the main shoot begins by formation in the axils of the uppermost assimilating leaves (the last in front of the apical inflorescence) – 1–2 lateral rosette shoots. These are future ramets (vegetative diasporas), which ensure, in the future, the vegetative reproduction of the individual and spread to new territories. Taking into account that in lakes of Tver oblast, Lobelia groupings form dense aggregated clusters on the bottom, the transition of individuals to a quasisenile age state (in the fifth year of life) enables them to rejuvenate and survive after the death of the maternal shoot. The formation and further development of rosette lateral shoots allows the plant to re-occupy the territory via vegetative or seed propagation. Complete morphological disintegration (vegetative reproduction) occurs in the fifth year of life. The genets’ ontogeny is completed by the formation of a compact clone from the detached lateral rosette shoots.


1991 ◽  
Vol 121 (7) ◽  
pp. 1099-1108 ◽  
Author(s):  
Douglas G. Burrin ◽  
Teresa A. Davis ◽  
Marta L. Fiorotto ◽  
Peter J. Reeds

2021 ◽  
Author(s):  
Elena S. Tkacheva ◽  
Ilya N. Medvedev

Modern pig farming is a significant sector of modern agriculture in many countries. The attractiveness of its products is associated with their excellent taste and economic affordability. The intensive development of pig breeding considers the latest achievements in the field of pig biology during their early ontogenesis. Optimal functioning of hemostasis in growing piglets relies on platelet activity. Its low severity during the phase of milk and vegetable nutrition provides them with the optimal functional state of primary hemostasis, the success of microcirculation in the internal organs, and sufficient activity of all functional and biochemical processes. In the blood of healthy piglets during the phase of dairy and plant nutrition, a decrease in the number of peroxidation products was noted due to an increase in the level of antioxidant protection of their plasma. This minimized their platelet and vascular wall alteration and provided optimal platelet-vascular interactions. This study shows that the gradual increase in the platelet aggregation that develops in piglets at this age is functionally balanced by the increase in the disaggregation properties of blood vessels and creates conditions for optimal blood flow in small-caliber vessels. Keywords: piglets, phase of dairy and plant nutrition, platelets, aggregation, disaggregation, early ontogenesis


2020 ◽  
Author(s):  
Miguel A. Gama Sosa ◽  
Rita De Gasperi ◽  
Gissel M. Perez ◽  
Patrick R. Hof ◽  
Gregory A. Elder

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