Characteristic of Poor Responder Patients and the success rate of biochemical pregnancy in the administration of adjuvant recombinant Luteinizing Hormones in Yasmin Clinic, Jakarta

KnE Medicine ◽  
2017 ◽  
Vol 1 (1) ◽  
pp. 193
Author(s):  
Devi Marischa ◽  
Gita Pratama ◽  
Mila Maidarti ◽  
Achmad K. Harzif ◽  
Budi Wiweko
Keyword(s):  
Success Rate ◽  
Poor Response ◽  
Poor Responder ◽  
Control Group ◽  
Cleavage Rate ◽  
Group Iii ◽  
Luteinizing Hormones ◽  
Biochemical Pregnancy ◽  
Significant Difference ◽  
Group Control Group

<p><strong>Introduction:</strong> Management for poor response patients is still a challenge for clinician engaged in Assisted Reproductive Technology. Various protocols have been proposed to improve the outcome for patients, though no RCT can provide the evidence based of success rate of one protocol among others.</p><p><strong>Objective:</strong> Our purpose is to find the basic data of poor responder patients in Yasmin Clinic, Jakarta and to assess the IVF cycle outcome after the addition of recombinant Luteinizing Hormones.</p><p><strong>Material and methods:</strong> This is a cohort retrospective study taken from medical records of IVF patients at Yasmin Clinic, Cipto Mangunkusumo Hospital between January 2012 to January 2015.</p><p><strong>Result :</strong>  Two hundreds and eighty-one poor response patients were selected for ART during January 2012 to January 2015, were divided into four main group. Control group received gonadotrophin protocol, while group II received additional recombinant Luteinizing hormones (rLH), Group III received additional Growth hormones (GH) and Group IV received additional rLH and GH both.</p><p><strong>Discussion:</strong> Our study demonstrated the follicle count, the oocyte count and the cleavage rate were statistically significant difference between control group and LH group. Where the oocyte count and follicle count were significantly higher, but the cleavage rate with LH showed negative correlation compare with control group.</p><strong>Conclusion : </strong>In this study we found that with adjuvant therapy with <em>recombinant Luteinizing Hormones, </em>produced higher follicles count and oocyte count.

Success Rate of Obturation of Root Canals by Different Techniques in Primary Molars: A Comparative Clinical Study

2020 ◽  
Vol 2 (1) ◽  
pp. 36-44
Author(s):  
Satyawan G. Damle ◽  
Ritika Bansal ◽  
Dhanashree D. Sakhare
Keyword(s):  
Success Rate ◽  
Study Groups ◽  
Primary Molars ◽  
Control Group ◽  
Second Primary ◽  
Chi Square ◽  
Exact Test ◽  
Root Canals ◽  
Significant Difference ◽  
Comparative Clinical Study

Objective: To compare the success rate of different obturation procedures in primary mandibular second molars clinically and also by digital radiovisiography. Methods: A total of 40 children aged between 4-8 years with deeply carious mandibular second primary molars indicated for single session pulpectomy were selected. Canals were obturated with Metapex. The 3 study groups (Endodontic plugger, Handheld lentulospiral, Navi Tip syringe) were compared with the control group (reamer) both clinically and radiovisiographically. The data collected were statistically analyzed using Pearson’s Chi-square and Fisher’s exact test. Results: The use of Navi tip syringe led to the least number of voids followed by Endodontic plugger and Reamer and the highest number of voids was reported with Lentulospiral. Navitip presented maximum number of optimally filled cases followed by Endodontic plugger and Lentulospiral and least number of optimally filled cases with reamer. However, there was no statistically significant difference (p>0.05) in any of the groups with clinical (pain and tenderness to percussion) and radiographic parameters (presence or absence of voids and length of obturation). Conclusion: Within the limitations of the present study, though the clinical outcome was statistically insignificant, Navitip syringe exhibited encouraging results and is a promising option for obturation in primary teeth.

Effect of Silver Nitrate Application on the Success of Endoscopic Dacryocystorhinostomy

2021 ◽  
pp. 194589242110427
Author(s):  
Yaser S. Çetin ◽  
Ramazan Akın ◽  
Ufuk Düzenli ◽  
Mahfuz Turan ◽  
Nazım Bozan
Keyword(s):  
Silver Nitrate ◽  
Success Rate ◽  
Postoperative Period ◽  
Revision Surgery ◽  
Granuloma Formation ◽  
Stent Insertion ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Silicone Stent

Objectives To compare the clinical outcomes of patients undergoing additional procedures in endoscopic endonasal dacryocystorhinostomy (End-DCR) surgery and discuss the factors affecting the success of End-DCR surgery in light of relevant literature. Methods The study included 155 patients who underwent End-DCR surgery in our clinic due to epiphora. This was a prospective randomized, single-blind, controlled trial. Group I (control) included 54 patients who did not undergo silicone stent insertion or silver nitrate application, group II included 51 patients who underwent silicone stent insertion only, and group III included 50 patients who underwent silver nitrate application only. Statistical analysis was performed on follow-up data regarding anatomic and functional success rates. Results Revision surgery was performed in 16 patients who developed persistent epiphora in the postoperative period, including 6 in group I, 7 in group II, and 3 in group III ( P = .4). The most common reason for revision surgery was stenosis of the neo-ostium ( n = 8), followed by granulation tissue formation ( n = 5) and synechia formation ( n = 3). Granuloma formation was the most common postoperative complication, and a significant difference was found among the groups with regard to granuloma formation ( P = .04). At postoperative month 12, the functional success rate was estimated to be 88%, 86%, and 94%, and the anatomic success rate was estimated to be 94%, 92%, and 96% in groups I, II, and III, respectively, with no significant difference, found among the 3 groups with regard to both rates ( P = .79 and P = .76, respectively). Conclusion The results indicated that stenting and silver nitrate application did not affect surgical success. Our preliminary results on silver nitrate cauterization showed that it is an effective, inexpensive, and practical method to reduce granulation formation in the postoperative period.

Impact of supplementing commercial rabbit pellets with fresh Moringa oleifera leaves on semen characteristics in rabbit bucks under tropical climate in Trinidad

2021 ◽  
Author(s):  
Krishna Mohan Kumar
Keyword(s):  
Sperm Motility ◽  
Moringa Oleifera ◽  
Sperm Count ◽  
Control Group ◽  
Computer Assisted ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Moringa Oleifera Leaves ◽  
The Impact

Objective This study aimed to evaluate the impact of the dietary supplement of Moringa oleifera leaves (MOL) on semen quality and characteristics in rabbits. Methods Eighteen (n=18) breeding bucks of New Zealand white, of similar age group, were used for the study. Three feeding regimes, (i) 100% commercial rabbit pellets (CRP)-Group I (ii) 90% CRP + 10% fresh MOL on a dry matter (DM) basis – Group II and (iii) 80% CRP + 20% fresh MOL on a DM basis – Group III, were adopted and the trial continued for 21 days. After adaptation to the diet, semen was collected from each buck and subjected to evaluation using a computer-assisted semen analyser. Results In Group III, the sperm count, normal sperm morphology, and sperm motility increased (52.0%) in comparison with the control (Group I; 50.1%). The inclusion of 20% Moringa oliefera in the diet (Group III) caused a significant increase (P<0.05) in semen concentration (Control =136.2 M/mL; Group III=297.2 M/mL). There was no significant difference (P>0.05) in sperm motility and semen volume among the groups. Conclusion The results suggest that supplementing commercial rabbit pellets with 20% fresh Moringa oliefera leaves on a DM basis can improve the quality and characteristics of semen in breeding bucks.

scholarly journals Effects of nano mineral-supplemented diet on sow productivity

2019 ◽  
Vol 41 (4) ◽  
Author(s):  
Hoang Nghia Son
Keyword(s):  
Birth Weight ◽  
Reproductive Performance ◽  
Metal Content ◽  
Mineral Content ◽  
Control Group ◽  
Average Weight ◽  
Group Iii ◽  
Newborn Piglets ◽  
Group I ◽  
Significant Difference

This study aimed to evaluate the effects of nano mineral-supplemented diet on sow productivity. The data were estimated by several parameters consisting of piglet live ratio at newborn stage and weaning stage, piglet weight at newborn stage and weaning stage, metal content in piglet livers. The results showed that live ratio of newborn piglets in group III was highest (93.44 ± 2.83%) comparing with other groups. However, there was no significant difference of live ratio in piglets at weaning stage between nano mineral-supplemented groups with control. The birth weight of piglets in nano mineral-supplemented groups was similar to control group. The birth weight of piglets in nano mineral-supplemented groups was ranged from 1,361.61 ± 47.37 grams (group II) to 1,410.48 ± 44.28 grams (group I). However, the average weight of weaned pigs in groups III and IV was higher than other groups (6,772.92 ± 105.47 grams and 6,818.87 ± 89.59 grams). Moreover, the amount of Fe, Cu, Zn, Mn in piglet liver from nano mineral-supplemented groups have been found to be lower than those in control group. These results revealed that the supplement of nano minerals for sows promoted the reproductive performance of sows and reduced mineral content in the liver of piglets. 

Urinary Claudin-1 Level as a Marker of Podocyte Injury in Patients with Proteinuria

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M E Nasser ◽  
S M Shawky ◽  
E A M Sanad
Keyword(s):  
Wide Spectrum ◽  
Cell Junction ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Podocyte Injury ◽  
Group Iii ◽  
Group I ◽  
Significant Difference ◽  
Diaphragm Cell ◽  
Control Study

Abstract Background The biology of claudins is a rapidly evolving field, and many intriguing questions remain unanswered. Although it had been assumed that the reason there are ≥24 isoforms of claudin is that each one has distinct permeability properties. The nephron displays a wide spectrum of claudins, whose distribution varies in each tubular segment. In diabetic nephropathy and glomerulonephritis the gene expression of claudin-1, is markedly upregulated in the podocyte, accompanied by a tighter filtration slit diaphragm (cell-cell junction made by the glomerular podocytes) and the appearance of TJ-like structures between the foot processes causing further podocytes injury and proteinuria. Aim of the work to assess urinary claudin -1 level as a marker of podocyte injury in patients with proteinuria. Patients and Methods it is a case control study which was conducted upon 90 subjects who were divided into three groups: group I included 30 patients with type II DM, group II included 30 patients with glomerulonephritis and group III had 30 healthy subjects as controls. Urinary claudin-1 level was measured by Enzyme linked Immunosorbent Assay (ELISA) Results In this study, we found that urinary claudin-1 level was significantly higher in diabetics group and GN group than in control group. In comparison between GN group and diabetic group, we found that urinary claudin-1 level was higher in GN group than in diabetics group but with no statistically significant difference between the two groups. Conclusion urinary claudin-1 level was significantly higher in diabetics and GN group and has positive correlation with uACR. So it can be used as marker of podocytes injury and proteinuria

The Role of sFas in the Immune Escape Mechanism and Progression of Cancer Larynx

2009 ◽  
Vol 2 ◽  
pp. CMENT.S2565
Author(s):  
Amr A El Badry ◽  
Ismail Elmofty ◽  
Amira Helmy
Keyword(s):  
Serum Level ◽  
Buffy Coat ◽  
Control Group ◽  
Group Iii ◽  
Soluble Fas ◽  
Group I ◽  
Significant Difference ◽  
Cancer Larynx ◽  
The Mean ◽  
Group Ii

This work assess serum levels of soluble Fas form (sFas) in patients with different stages of laryngeal squamous cell carcinoma(LSCC) to investigate its prognostic significance. We correlate its levels with the morphological changes of peripheral blood cells via buffy coat examinatin. The study population included 70 patients clinically diagnosed and pathohistologically confirmed LSCC in addition to 20 healthy controls. According to TNM classification 33(47.1%) patients were in stage I (group I) and 24(34.3%) in stage II (group II), 13(18.5%) in stage III (group III). The results revealed that the mean serum level of sFas (pg/ml) in the control group was 51.2, in group I was 66.33, in group II was 81.33 and in group III was 112.45. Statistical analysis of the mean of sFas by ELISA test in the patients' groups in comparison to the control revealed a significant increase of both group II and III in comparison to the control group (P < 0.01) but there was no significant difference (P > 0.05) between group I in comparison to either the control or group II. There was a significant difference (P < 0.05) between group I in comparison to group III. LM examination revealed massive extent of the apoptotic cells in group III when compared to both group I and group II. EM examination of the buffy coat revealed apoptotic changes, mainly in the peripheral blood mononuclear cells (PBMNCs), represented by surface membrane ruffles and blebs with clumped nuclear chromatin and vacuolated cytoplasm. In conclusion, this study may help us to better understand one of the escape mechanisms in cancer larynx. This mechanism is represented by the significant increase in both the serum level of sFas and the morphological apoptotic changes that detected in PBMNCs. Soluble Fas may contribute to the progression of laryngeal cancer. It can be used as an attractive target for anticancer therapy and may be considered as a marker of disease progression and poor prognosis in laryngeal cancer.

scholarly journals Serum Hepcidin Level as a Marker of Iron Status in Children with Cystic Fibrosis

2018 ◽  
Vol 2018 ◽  
pp. 1-8
Author(s):  
Monika Kałużna-Czyż ◽  
Urszula Grzybowska-Chlebowczyk ◽  
Halina Woś ◽  
Sabina Więcek
Keyword(s):  
Cystic Fibrosis ◽  
Iron Status ◽  
Full Blood Count ◽  
Control Group ◽  
Hepcidin Level ◽  
Significant Difference ◽  
Serum Hepcidin ◽  
Liver Markers ◽  
Group Control Group ◽  
Active Inflammation

Introduction. Iron deficiency is common in patients with cystic fibrosis. Conventional iron status markers are often abnormal in patients with CF, reflecting inflammation and/or infection, rather than actual iron stores. The aim was to evaluate serum hepcidin levels against selected iron status markers, assuming that hepcidin may be a more sensitive indicator of iron management in patients with active inflammation, such as those with CF. Material and Methods. 46 children with cystic fibrosis and 31 healthy controls were enrolled. Hepcidin concentration was evaluated, along with the following other blood assays: full blood count, Fe, ferritin, transferrin, TIBC, liver markers, and CRP. Results. Higher ferritin and CRP levels as well as lower TIBC levels significantly predicted hepcidin levels in the study group, control group, and the entire sample. There was no significant difference in hepcidin levels between the patients and controls. Children with exacerbations had significantly higher hepcidin levels than those with stable disease. These findings support the serum hepcidin level as useful in assessing iron status in children with cystic fibrosis. It may also be useful in early detection and monitoring of treatment of exacerbations.

scholarly journals The Effect of Kelulut Honey on Fasting Blood Glucose and Metabolic Parameters in Patients with Impaired Fasting Glucose

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Mohd Radzniwan Rashid ◽  
Khairun Nain Nor Aripin ◽  
Fathima Begum Syed Mohideen ◽  
Nizam Baharom ◽  
Khairani Omar ◽  
...  
Keyword(s):  
Impaired Fasting Glucose ◽  
Fasting Glucose ◽  
Low Density Lipoprotein ◽  
Fasting Blood Glucose ◽  
Daily Intake ◽  
Density Lipoprotein ◽  
Metabolic Parameters ◽  
Control Group ◽  
Significant Difference ◽  
Group Control Group

Background. Impaired fasting glucose (IFG) poses a higher risk of diabetes. Honey has been reported to improve metabolic abnormalities including lowering hyperglycemia. This study is sought at determining the effect of Malaysian Kelulut honey (KH) on fasting glucose levels and metabolic parameters in IFG patients. Methods. This quasi-experimental intervention study of 30-day duration was conducted among 60 adult patients with IFG. They were allocated into taking 30 g/day KH group (experimental group, n=30) and not taking KH group (control group, n=30). Body mass index (BMI), waist circumference, blood pressure (BP), fasting glucose, and lipid profile levels (total cholesterol, triglyceride, high-density lipoprotein, and low-density lipoprotein) were measured before and after treatment. Results. There was no significant difference in all measured variables at day 30 compared to day 1 within both groups. Similarly, all measured variables neither at day 1 nor at day 30 had shown a statistically significant difference between the groups. Conclusions. Daily intake of 30 g KH for 30 days resulted in insignificant effect on fasting glucose, fasting lipid profiles, and other metabolic parameters in patients with IFG. Further studies that employ longer study duration are needed to ascertain the finding.

scholarly journals EFFECTS OF TRAINING SIDE HOP OVER BARRIER WITH DUMBELL AND HEXAGON WITH DUMBELL ON LEG STRENGTH AND LEG POWER

2018 ◽  
Vol 2 (2) ◽  
pp. 46
Author(s):  
Nur Akbari ◽  
Oce Wiriawan ◽  
Nining Widyah Kusnanik
Keyword(s):  
Control Group ◽  
Percentage Increase ◽  
Design Data ◽  
Group Iii ◽  
Strength Group ◽  
Leg Strength ◽  
Group I ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Group Ii

This study was conducted at 45 students of SMAN 1 Cerme with aged between 15-16 years old. Students were  divided into 3 groups. the type of research used quantitative with quasi-experimental approach. Instruments of this study were test of leg strength and leg power using Leg Dynamometer and  Jump MD. The research design used matching only design. Data was anlyzed using ANOVA. The results of the  research was found that training program side hop over  barrier with dumbell and hexagon with  dumbbell significantly increase at leg strength and leg power (Sig. 0.000 <α = 0.05). Group I, Group II and Group III had significant difference (Sig. 0.000 α = 0.005). Percentage increase in leg strength group 1 of 1,80% and leg  power of 15,49%. Percentage increase in leg strength group II of  1,68% and a power of 14,27% and whereas in the control group increase in leg strength was 1.67% power at 12.32%.It can be concluded that There was an increase in leg strength and leg power in each group after the training was given. In addition, there were differences among the three groups effects seen improved in leg strength and leg power through ANOVA, where the training side hop over barrier with dumbbell and hexagon with dumbell had increased in leg strength and leg   power. But side hop over barrier with dumbbell had more significant increased than hexagon with dumbbell. Key words: Side hop over with barrier dumbell,  hexagon with dumbell, leg strength and leg power.

scholarly journals Acute Effects of Static and Dynamic Stretching on Jump Performance of Volleyball Players

2021 ◽  
Vol 4 (3) ◽  
Author(s):  
Yasemin Arı ◽  
◽  
Ozan Sever ◽  
Aslıhan Arslangörür ◽  
Asım Tunçel ◽  
...  
Keyword(s):  
Rank Test ◽  
Control Group ◽  
Static Stretching ◽  
Acute Effects ◽  
Jump Performance ◽  
Dynamic Stretching ◽  
Friedman Analysis ◽  
Significant Difference ◽  
Volleyball Players ◽  
Group Control Group

The aim of this study is to examine the acute effects of different stretching methods on jump performance of volleyball players. 11 female volleyball players (age: 24.36 ± 5.10 years; height: 177.81 ± 7.30 cm; weight: 68.17 ± 11.69 kg; body mass index (BMI): 21.46 ± 2.56 kg.m-2; sports age: 12.72 ± 5.31 years) have participated voluntarily in this study. The players have applied three different stretching protocols such as control (no stretching), static and dynamic stretching on non-consecutive days. The protocols have included 5 minutes general warm-up, 1 minute rest, 30-second stretch program for each muscle group (control group not included), 1 minute rest and countermovement jump (CMJ), squat jump (SJ) and standing long jump (SLJ) tests. Friedman analysis has been used for data analysis. Wilcoxon Signed Rank Test has been implemented in order to determine the difference among groups. At the end of the study, a significant difference has been found between control and dynamic stretching groups with regard to static stretching groups in view of CMJ and SJ performance findings (p <0.05). It has been found that there is a statistically significant difference in the test averages of dynamic stretching group compared to static stretching group in view of SLJ performance findings (p <0.05). This study shows that static stretching practices reduce the jumping performance of the players. As a result, it can be suggested that trainers should use dynamic stretching methods before the trainings on jumping properties containing explosive movements.

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