The Prevalence of Dermatophytosis and its Etiologic Agents in Clients of Mycology Laboratory of Yazd Central Laboratory in 2013-2018

Introduction: Dermatophytosis is one of the health problems that may spread from contaminated soil, pets, livestock, and infected humans. Although Tinea capitis is more prevalent in deprived areas, other forms of this disease were also reported in both urban and rural regions. In order to design appropriate strategies to control and treat diseases, the disease prevalence and its effective factors should be investigated. The aim of this study was to determine the prevalence rate of dermatophytosis and its etiologic agents in patients who referred to the mycology laboratory of Yazd Central Laboratory during 2013-2018. Methods: In this cross-sectional descriptive study, samples were collected from suspected dermatophytic lesions of patients who referred to the mycology section of Yazd Central Medical Laboratory during 2013-2018. After completing the demographic information questionnaire, samples were collected from the lesions and examined by direct microscopic culture examination. Moreover, additional tests were performed to determine the genus and species of the etiologic agents. Results: From 900 patients, 112 cases (12.5%) were positive regarding both direct smear and culture. The highest rate of infection was observed in the age group less than 10 years. The most common clinical forms were tinea corporis, capitis, cruris, manuum, pedis, and ungium, respectively. The most commonly isolated etiologic agents were Trichophyton mentagrophytes, Microsporum canis, Trichophyton rubrum, and Trichophyton verrucosum. Conclusion: Due to the lack of information about the current status of this disease in Yazd, periodical studies are recommended on dermatophytosis, their sources, and etiologic agents in order to take effective measures to control and prevent the disease.

Download Full-text

Current trends of antibiotic resistance among human skin infections causing bacteria; a cross-sectional study

Journal of Dermatology & Cosmetology ◽

10.15406/jdc.2021.05.00189 ◽

2021 ◽

Vol 5 (4) ◽

pp. 88-91

Author(s):

Muddasir Khan

Keyword(s):

Bacterial Species ◽

Treatment Strategies ◽

Cross Sectional Study ◽

Medical Laboratory ◽

Current Status ◽

Antibiotics Resistance ◽

Skin Infections ◽

Sectional Study ◽

Cross Sectional ◽

Klebsiella Spp

Objectives: To determine the current status of skin infections causing bacteria and their pattern of resistance to widely used antibiotics among the physician referred patients in district Peshawar, Pakistan. Materials and methods: A cross-sectional study of 164 pus samples from diseased patients, referred by physicians was done for a period from February 2020 to January 2021 at Department of Microbiology, Complex medical laboratory and Research center, Peshawar, Pakistan. Results: The bacterial growth were obtained in 88 pus samples. Among these isolated bacterial species Escherichia coli was the most prevalent pathogen, present in (46%), Staphylococcus aureus (39%), Proteus species (11%), Klebseilla species (2%) and Pseudomonas aerugenosa (2%), respectively. Among the tested antibiotics resistance wise E.coli was highly resistance to Ampicillin (92.5%), S. Aureus to Levofloxacin (91.1%), Proteus spp .to Doxycycline (90%), Klebsiella spp. to Meropenem (100%), Amoxicillin (100%) and P. aeruginosato Aztreonam (100%), Doxycycline (100%), respectively.Sensitivity wise E.coli was highly sensitive to Amikacin (90%), S. aureus to Meropenem (91.1%) and Doxycycline (91.1%),Proteus spp. to Meropenem (100%), Klebsiella spp. to Ciprofloxacin (100%), Cefotaxime (100%), Aztreonam (100%) and Doxycycline (100%), P. aeruginosa to Amikacin (100%), Meropenem(100%), Ciprofloxacin (100%), Gentamicin (100%), Cefotaxime (100%), Ceftriaxone (100%), Ampicillin (100%) and Cefotaxime (100%), respectively. Conclusion: The most prevalent skin infections causing bacteria was E.coli, followed by S. aureus, Proteus spp., Klebseilla spp. and P. aerugenosa, respectively. The antibiogram provides adequate knowledge of effective therapeutic agents for the treatment strategies of skin infections.

Download Full-text

Dermatophyte agents in the city of São Paulo, from 1992 to 2002

Revista do Instituto de Medicina Tropical de São Paulo ◽

10.1590/s0036-46652003000500004 ◽

2003 ◽

Vol 45 (5) ◽

pp. 259-263 ◽

Cited By ~ 34

Author(s):

Patricia Augusta Vianna Chimelli ◽

Alexandre de Abreu Sofiatti ◽

Ricardo Spina Nunes ◽

Jose Eduardo da Costa Martins

Keyword(s):

Clinical Manifestations ◽

Trichophyton Mentagrophytes ◽

Sao Paulo ◽

Microsporum Canis ◽

Microsporum Gypseum ◽

São Paulo ◽

Epidermophyton Floccosum ◽

Etiologic Agents ◽

Clinical Variants ◽

The City

Dermatophytosis are superficial mycoses caused by fungi that can invade stratum corneum and keratinized tissues. In order to study the frequency of dermatophytes species and the clinical manifestations caused by these fungi, in São Paulo, SP, Brazil, the authors analyzed cultures isolated at the Mycology Laboratory from a selected population (15,300 out-patients of the Hospital das Clínicas, Department of Dermatology, Faculty of Medicine of University of São Paulo) from January 1992 to June 2002. The most prevalent dermatophyte was Trichophyton rubrum (48.7%), followed by Microsporum canis (20.9%), Trichophyton tonsurans (13.8%), Trichophyton mentagrophytes (9.7%), Epidermophyton floccosum (4.1%), and Microsporum gypseum (2.5%). These agents determined more than one clinical manifestation, i.e., tinea corporis (31.5%), tinea capitis (27.5%), tinea unguium (14.8%), tinea cruris (13.9%), tinea pedis (9.9%), and tinea manuum (1.9%). Clinical variants of dermatophytosis and their relationship to the etiologic agents were studied and the results were compared to those obtained in previous studies in other regions of Brazil and in other countries.

Download Full-text

Dermatophyte Profile in Patients with Dermatophytosis in Polyclinic Dermatology and Venerology of the General Hospital Dr. Ferdinand Lumbantobing Sibolga in 2019

Sumatera Medical Journal ◽

10.32734/sumej.v4i2.5602 ◽

2021 ◽

Vol 4 (2) ◽

Author(s):

May Iyasya Sarumpaet ◽

Dian Dwi Wahyuni

Keyword(s):

Trichophyton Rubrum ◽

Trichophyton Mentagrophytes ◽

Antifungal Drugs ◽

Tinea Corporis ◽

Observational Research ◽

Microsporum Canis ◽

Cross Sectional ◽

Superficial Skin ◽

Cross Sectional Design

Dermatophytosis is a superficial skin infection caused by dermatophytes that infected keratinous skin tissue, dermatophytes form molecules that bind to keratin as a source of nutrients in the formation of colonization. Dermatophytes that cause dermatophytosis are Tricophyton sp, Epidermophyton sp and Microsporum sp. To find out the Profile of dermatophytes in patients with dermatophytosis in the Polyclinic of Dermatology and Venerology Dr. Ferdinand Lumbantobing Sibolga in 2019 conducted observational research with cross sectional design. The sample of this study were 75 patients who were new patients and had not used antifungal drugs. This sample is then examined by examination of KOH and cultured and then identified by Scotch-tape Preparation in a microscope. The prevalence of dermatophytosis in this study was 23% of skin cases. The majority of dermatophytosis patients are women (52%), the most age group is 46-65 years (30.7%) and is most often found in housewives (24%). The dermatophytes species found were Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis with the most species Trichophyton rubrum (37.3%), which was then followed by Trichophyton mentagrophytes (16%). Tinea corporis, tinea cruris, tinea capitis, tinea pedis and tinea unguinum are dermatophytosis cases that were found in this study. It can be concluded that Trichophyton rubrum is the most common cause of dermatophytosis in Dr. Ferdinand Lumbantobing Sibolga with Tinea corporis is the most classified classification of dermatophytosis.

Download Full-text

Contrast-enhanced ultrasound of the abdominal aorta – current status and future perspectives

VASA ◽

10.1024/0301-1526/a000749 ◽

2019 ◽

Vol 48 (2) ◽

pp. 115-125 ◽

Cited By ~ 4

Author(s):

Xin Li ◽

Daniel Staub ◽

Vasileios Rafailidis ◽

Mohammed Al-Natour ◽

Sanjeeva Kalva ◽

...

Keyword(s):

Real Time ◽

Vascular Diseases ◽

Aneurysm Rupture ◽

Vasa Vasorum ◽

Current Status ◽

Contrast Enhanced Ultrasound ◽

Aortic Diseases ◽

Cross Sectional ◽

Vascular Abnormalities ◽

Contrast Enhanced

Abstract. Ultrasound has been established as an important diagnostic tool in assessing vascular abnormalities. Standard B-mode and Doppler techniques have inherent limitations with regards to detection of slow flow and small vasculature. Contrast-enhanced ultrasound (CEUS) is a complementary tool and is useful in assessing both the macro- and microvascular anatomy of the aorta. CEUS can also provide valuable physiological information in real-time scanning sessions due to the physical and safety profiles of the administered microbubbles. From a macrovascular perspective, CEUS has been used to characterize aortic aneurysm rupture, dissection and endoleaks post-EVAR repair. With regard to microvasculature CEUS enables imaging of adventitial vasa vasorum thereby assessing aortic inflammation processes, such as monitoring treatment response in chronic periaortitis. CEUS may have additional clinical utility since adventitial vasa vasorum has important implications in the pathogenesis of aortic diseases. In recent years, there have been an increasing number of studies comparing CEUS to cross-sectional imaging for aortic applications. For endoleak surveillance CEUS has been shown to be equal or in certain cases superior in comparison to CT angiography. The recent advancement of CEUS software along with the ongoing development of drug-eluting contrast microbubbles has allowed improved targeted detection and real-time ultrasound guided therapy for aortic vasa vasorum inflammation and neovascularization in animal models. Therefore, CEUS is uniquely suited to comprehensively assess and potentially treat aortic vascular diseases in the future.

Download Full-text

Psychological Resilience Provides No Independent Protection From Suicidal Risk

Crisis ◽

10.1027/0227-5910/a000364 ◽

2016 ◽

Vol 37 (2) ◽

pp. 130-139 ◽

Cited By ~ 9

Author(s):

Danica W. Y. Liu ◽

A. Kate Fairweather-Schmidt ◽

Richard Burns ◽

Rachel M. Roberts ◽

Kaarin J. Anstey

Keyword(s):

Risk Factors ◽

Well Being ◽

Current Status ◽

Psychological Resilience ◽

Cross Sectional ◽

Life Project ◽

Resilience Factors ◽

First Time

Abstract. Background: Little is known about the role of resilience in the likelihood of suicidal ideation (SI) over time. Aims: We examined the association between resilience and SI in a young-adult cohort over 4 years. Our objectives were to determine whether resilience was associated with SI at follow-up or, conversely, whether SI was associated with lowered resilience at follow-up. Method: Participants were selected from the Personality and Total Health (PATH) Through Life Project from Canberra and Queanbeyan, Australia, aged 28–32 years at the first time point and 32–36 at the second. Multinomial, linear, and binary regression analyses explored the association between resilience and SI over two time points. Models were adjusted for suicidality risk factors. Results: While unadjusted analyses identified associations between resilience and SI, these effects were fully explained by the inclusion of other suicidality risk factors. Conclusion: Despite strong cross-sectional associations, resilience and SI appear to be unrelated in a longitudinal context, once risk/resilience factors are controlled for. As independent indicators of psychological well-being, suicidality and resilience are essential if current status is to be captured. However, the addition of other factors (e.g., support, mastery) makes this association tenuous. Consequently, resilience per se may not be protective of SI.

Download Full-text

Anaesthesiology in China: A cross-sectional survey of the current status of anaesthesiology departments

The Lancet Regional Health - Western Pacific ◽

10.1016/j.lanwpc.2021.100166 ◽

2021 ◽

Vol 12 ◽

pp. 100166

Author(s):

Changsheng Zhang ◽

Shengshu Wang ◽

Hange Li ◽

Fan Su ◽

Yuguang Huang ◽

...

Keyword(s):

Current Status ◽

Cross Sectional Survey ◽

Cross Sectional

Download Full-text

The effects of disease-related knowledge on illness perception and psychological status of patients with COVID-19 in Hunan, China

Disaster Medicine and Public Health Preparedness ◽

10.1017/dmp.2021.33 ◽

2021 ◽

pp. 1-30

Author(s):

Man Ye ◽

Shi-hao Chen ◽

Xu-ting Li ◽

Jin Huang ◽

Ran-ran Mei ◽

...

Keyword(s):

Low Income ◽

Illness Perception ◽

Self Care ◽

The Elderly ◽

Diagnosis And Treatment ◽

Psychological Status ◽

Current Status ◽

Average Score ◽

Future Health ◽

Cross Sectional

Abstract OBJECTIVE: To assess the current status of disease-related knowledge and to analyze the relationship among the general condition, illness perception, and psychological status of patients with COVID-19. METHODS: A hospital-based cross-sectional study was conducted on 118 patients using convenience sampling. The general questionnaire, disease-related knowledge questionnaire of COVID-19, Revised Illness Perception Questionnaire (IPQ-R), and Profile of Mood States (POMS) were used to measure the current status of participants. RESULTS: The overall average score of the disease-related knowledge of patients with COVID-19 was (79.19 ± 14.25), the self-care situation was positively correlated with knowledge of prevention and control (r=0.265, P=0.004) and total score of disease-related knowledge (r= 0.206, P= 0.025); the degree of anxiety was negatively correlated with the knowledge of diagnosis and treatment (r= -0.182, P= 0.049). The score of disease-related knowledge was negatively correlated with negative cognition (volatility, consequences, emotional statements) and negative emotions (tension, fatigue, depression) (P<0.05); positively correlated with positive cognition (disease coherence) and positive emotion (self-esteem) (P<0.05). CONCLUSION It was recommended that we should pay more attention to the elderly and low-income groups, and increase the knowledge about diagnosis and treatment of COVID-19 and self-care in the future health education for patients.

Download Full-text

Monitoring, implementation and reporting of interventions in a selection of trials assessing exercise therapy for the management of shoulder subacromial pain: a cross-sectional investigation

BMJ Open ◽

10.1136/bmjopen-2020-044462 ◽

2021 ◽

Vol 11 (2) ◽

pp. e044462

Author(s):

Daniel C Ribeiro ◽

Kate Spiers ◽

Laura Thomas ◽

Kiriffi Leilua ◽

Matthew Wilkes ◽

...

Keyword(s):

Manual Therapy ◽

Exercise Intervention ◽

Cochrane Review ◽

Health Behavior Change ◽

Cross Sectional ◽

Treatment Delivery ◽

Lack Of Information ◽

Intervention Trials ◽

Intervention Description ◽

Selection Of

ObjectivesTo review the reporting of monitoring and implementation of interventions in a selection of trials that assessed the effectiveness of manual therapy and exercise in the management of shoulder subacromial pain.DesignA review of trials assessing the effectiveness of manual therapy and exercise in the management of patients with shoulder subacromial pain.MethodsWe included in our review a selection of 10 trials that were included in a Cochrane review and compared manual therapy and exercise intervention with another intervention. Trials were assessed independently by two reviewers using two checklists: the Template for Intervention Description and Replication (TIDieR) and the Health Behavior Change Consortium treatment fidelity (National Institutes of Health Behaviour Change Consortium/NIHBCC).ResultsTIDieR overall scores for individual trials ranged from 11.1% to 45% and fidelity scores ranged from 7% to 50%. On average, trials scored the following within each domain of NIHBCC: study design 51%; training of providers 8%; treatment delivery 15%; treatment receipt 14% and treatment enactment 2.5%.ConclusionsLittle information about the monitoring, implementation and reporting of interventions was provided by trials and that is a barrier for implementing or replicating these interventions. The lack of information regarding the implementation of interventions needs to be taken into account when assessing whether effectiveness of interventions was impacted by their design or due to deviations from the protocol within trials.

Download Full-text

Obstetric Violence in Spain (Part III): Healthcare Professionals, Times and Areas

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18073359 ◽

2021 ◽

Vol 18 (7) ◽

pp. 3359

Author(s):

Desirée Mena-Tudela ◽

Susana Iglesias-Casás ◽

Víctor Manuel González-Chordá ◽

María Jesús Valero-Chillerón ◽

Laura Andreu-Pejó ◽

...

Keyword(s):

Public Health ◽

Primary Care ◽

Informed Consent ◽

Healthcare Professionals ◽

Public Health Problem ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Lack Of Information ◽

Obstetric Violence

Background: Obstetric violence is a worldwide public health problem, which seems greater in Spain. As no studies were found that identify the most representative healthcare professionals, times, and areas involved in obstetric violence, the objective of this work was to study at what time of maternity, with which professionals, and in what areas women identified obstetric violence. Methods: This descriptive, retrospective, and cross-sectional study was performed from January 2018 to June 2019. The main variables were the area (hospital, primary care, both), the time (pregnancy, birth, puerperium), and the professionals attending to women. Results: Our sample comprised 17,541 participants. The area identified with the most obstetric violence for the different studied variables was hospitals. Women identified more obstetric violence at time of birth. Findings such as lack of information and informed consent (74.2%), and criticism of infantile behavior and treatment (87.6%), stood out. The main identified healthcare professionals were midwives and gynecologists, and “other” professionals repeatedly appeared. Conclusions: Having identified the professionals, times, and areas of most obstetric violence in Spain, it seems necessary to reflect on not only the Spanish National Health System’s structure and management but also on healthcare professionals’ training.

Download Full-text

Relevance of monitoring transmural disease activity in patients with Crohn’s disease: current status and future perspectives

Therapeutic Advances in Gastroenterology ◽

10.1177/17562848211006672 ◽

2021 ◽

Vol 14 ◽

pp. 175628482110066

Author(s):

Rune Wilkens ◽

Kerri L. Novak ◽

Christian Maaser ◽

Remo Panaccione ◽

Torsten Kucharzik

Keyword(s):

Crohn’S Disease ◽

Crohn's Disease ◽

Disease Activity ◽

Symptom Control ◽

Current Status ◽

Clinical Relapse ◽

Cross Sectional ◽

Treatment Targets ◽

Endoscopic Remission ◽

Transmural Inflammation

Treatment targets of inflammatory bowel diseases (IBD), ulcerative colitis (UC) and Crohn’s disease (CD) have evolved over the last decade. Goals of therapy consisting of symptom control and steroid sparing have shifted to control of disease activity with endoscopic remission being an important endpoint. Unfortunately, this requires ileocolonoscopy, an invasive procedure. Biomarkers [C-reactive protein (CRP) and fecal calprotectin (FCP)] have emerged as surrogates for endoscopic remission and disease activity, but also have limitations. Despite this evolution, we must not lose sight that CD involves transmural inflammation, not fully appreciated with ileocolonoscopy. Therefore, transmural assessment of disease activity by cross-sectional imaging, in particular with magnetic resonance enterography (MRE) and intestinal ultrasonography (IUS), is vital to fully understand disease control. Bowel-wall thickness (BWT) is the cornerstone in assessment of transmural inflammation and BWT normalization, with or without bloodflow normalization, the key element demonstrating resolution of transmural inflammation, namely transmural healing (TH) or transmural remission (TR). In small studies, achievement of TR has been associated with improved long-term clinical outcomes, including reduced hospitalization, surgery, escalation of treatment, and a decrease in clinical relapse over endoscopic remission alone. This review will focus on the existing literature investigating the concept of TR or residual transmural disease and its relation to other existing treatment targets. Current data suggest that TR may be the next logical step in the evolution of treatment targets.

Download Full-text