Maternal Anxiety, Depression, and Stress during Pregnancy and Neonatal Growth Indices at Birth

Maternal Age ◽

Emotional Health ◽

Longitudinal Survey ◽

Maternal Anxiety ◽

Growth Indices ◽

Younger Age ◽

Severity Of Depression ◽

Neonatal Growth ◽

Background: Anxiety, depression, and stress during the pregnancy period are usually overlooked in women despite their detrimental effects on the mother and infant. Studies have shown an increase in the risk of behavioral and psychological problems in an infant's life because of the mother's exposure to negative excitement and stress before childbirth. In the present study, we aimed to assess the effect of maternal anxiety, depression, and stress during pregnancy on neonatal growth indices at birth. Methods: This longitudinal survey was done on 102 pregnant women referred to the obstetrics clinic of Shahid Sadoughi Hospital of Yazd for prenatal care from September 2019 to March 2020. They were asked to fulfill two questionnaires related to the study. After delivery, the further information and growth indices of neonates were extracted by telephone. Results: Regardless of the severity of depression, anxiety, and stress, a significant relationship was found between maternal age and stress (P= 0.033), so in mothers with younger age, pregnancy stress was more. Moreover, the study showed a significant relationship between height and maternal anxiety (P = 0.018). Conclusion: Based on the findings of this study and due to the possible association of neonatal indices with maternal anxiety, depression, and stress during pregnancy, more attention to maternal emotional health seems necessary.

Stress, anxiety, depression and burnout in frontline health care workers during COVID-19 pandemic: a brief systematic review and new data from Russia

10.31234/osf.io/je3ch ◽

2021 ◽

Author(s):

Ekaterina Mosolova ◽

Dmitry Sosin ◽

Sergey Mosolov

Keyword(s):

Risk Factors ◽

Systematic Review ◽

Female Gender ◽

Assessment Tools ◽

Care Workers ◽

Younger Age ◽

Wide Range ◽

Associated Risk Factors ◽

Anxiety Depression ◽

The Impact

During the COVID-19 pandemic, healthcare workers (HCWs) have been subject to increased workload while also exposed to many psychosocial stressors. In a systematic review we analyze the impact that the pandemic has had on HCWs mental state and associated risk factors. Most studies reported high levels of depression and anxiety among HCWs worldwide, however, due to a wide range of assessment tools, cut-off scores, and number of frontline participants in the studies, results were difficult to compare. Our study is based on two online surveys of 2195 HCWs from different regions of Russia during spring and autumn epidemic outbreaks revealed the rates of anxiety, stress, depression, emotional exhaustion and depersonalization and perceived stress as 32.3%, 31.1%, 45.5%, 74.2%, 37.7% ,67.8%, respectively. Moreover, 2.4% of HCWs reported suicidal thoughts. The most common risk factors include: female gender, nurse as an occupation, younger age, working for over 6 months, chronic diseases, smoking, high working demands, lack of personal protective equipment, low salary, lack of social support, isolation from families, the fear of relatives getting infected. These results demonstrate the need for urgent supportive programs for HCWs fighting COVID-19 that fall into higher risk factors groups.

Anxiety, depression, fatigue, and headache burden in the pediatric hydrocephalus population

Journal of Neurosurgery Pediatrics ◽

10.3171/2020.4.peds19697 ◽

2020 ◽

Vol 26 (5) ◽

pp. 483-489 ◽

Cited By ~ 1

Author(s):

Kathrin Zimmerman ◽

Bobby May ◽

Katherine Barnes ◽

Anastasia Arynchyna ◽

Elizabeth N. Alford ◽

...

Keyword(s):

General Population ◽

Emotional Health ◽

Chronic Medical Condition ◽

Measurement Information ◽

Burden Of Headache ◽

Pediatric Hydrocephalus ◽

Patient Reported ◽

The Mean ◽

Moderate Range ◽

OBJECTIVEChildhood hydrocephalus is a common chronic medical condition. However, little is known about the burden of headache and psychological comorbidities in children living with hydrocephalus. The purpose of this study was to determine the prevalence and severity of these conditions among the pediatric hydrocephalus population.METHODSDuring routine neurosurgery clinic visits from July 2017 to February 2018, the authors administered four surveys to children ages 7 years and older: Pediatric Migraine Disability Assessment (PedMIDAS), Patient-Reported Outcomes Measurement Information System (PROMIS) Anxiety, PROMIS Depression, and PROMIS Fatigue. The PedMIDAS is an assessment of headache disability in pediatric and adolescent patients. The PROMIS measures are pediatric self-reported instruments to assess social and emotional health. PROMIS measures utilize T-scores (mean 50, SD 10) to compare anxiety, depression, and fatigue in specific populations to those in the US general population. Clinical and demographic data were collected from the medical record (hydrocephalus etiology, shunt infection, race, etc.) and tested for associations with survey measure scores.RESULTSForty children completed the PedMIDAS. Ten percent of them were in the severe headache range, 5% were in the moderate range, and 5% were in the mild range. There was a statistically significant association between undergoing a cluster of shunt operations and headache burden (p = 0.003).Forty children completed all three PROMIS measures. The mean anxiety score was 45.8 (SD 11.7), and 2.5% of children scored in the severe anxiety range, 17.5% in the moderate range, and 20% in the mild range. The mean depression score was 42.7 (SD 10.0), with 2.5% of children scoring in the severe depression range, 5% in the moderate range, and 12.5% in the mild range. The mean fatigue score was 45.1 (SD 16.4), with 15% percent of children scoring in the severe fatigue range, 10% in the moderate range, and 7.5% in the mild range. There were no statistically significant associations between child anxiety, depression, or fatigue and clinical or demographic variables.CONCLUSIONSChildren with hydrocephalus have an average burden of headache, anxiety, depression, and fatigue as compared to the general population overall. Having a cluster of shunt operations correlates with a higher headache burden, but no clinical or demographic variable is associated with anxiety, depression, or fatigue.

Hydrocephalus-related quality of life as assessed by children and their caregivers

Journal of Neurosurgery Pediatrics ◽

10.3171/2020.4.peds19660 ◽

2020 ◽

Vol 26 (4) ◽

pp. 353-363 ◽

Cited By ~ 1

Author(s):

Kathrin Zimmerman ◽

Bobby May ◽

Katherine Barnes ◽

Anastasia Arynchyna ◽

Elizabeth N. Alford ◽

...

Keyword(s):

Posttraumatic Stress ◽

Traumatic Stress ◽

Pediatric Patients ◽

Emotional Health ◽

Social Emotional ◽

Proxy Report ◽

Cognitive Health ◽

The Mean ◽

OBJECTIVEHydrocephalus is a chronic medical condition that has a significant impact on children and their caregivers. The objective of this study was to measure the quality of life (QOL) of children with hydrocephalus, as assessed by both caregivers and patients.METHODSPediatric patients with hydrocephalus and their caregivers were enrolled during routine neurosurgery clinic visits. The Hydrocephalus Outcomes Questionnaire (HOQ), a report of hydrocephalus-related QOL, was administered to both children with hydrocephalus (self-report) and their caregivers (proxy report about the child). Patients with hydrocephalus also completed measures of anxiety, depression, fatigue, traumatic stress, and headache. Caregivers completed a proxy report of child traumatic stress and a measure of caregiver burden. Demographic information was collected from administration of the Psychosocial Assessment Tool (version 2.0) and from the medical record. Child and caregiver HOQ scores were analyzed and correlated with clinical, demographic, and psychological variables.RESULTSThe mean overall HOQ score (parent assessment of child QOL) was 0.68. HOQ Physical Health, Social-Emotional Health, and Cognitive Health subscore averages were 0.69, 0.73, and 0.54, respectively. The mean overall child self-assessment (cHOQ) score was 0.77, with cHOQ Physical Health, Social-Emotional Health, and Cognitive Health subscore means of 0.84, 0.79, and 0.66, respectively. Thirty-nine dyads were analyzed, in which both a child with hydrocephalus and his or her caregiver completed the cHOQ and HOQ. There was a positive correlation between parent and child scores (p < 0.004 for all subscores). Child scores were consistently higher than parent scores. Variables that showed association with caregiver-assessed QOL in at least one domain included child age, etiology of hydrocephalus, and history of endoscopic third ventriculostomy. There was a significant negative relationship (rho −0.48 to −0.60) between child-reported cHOQ score and child-reported measures of posttraumatic stress, anxiety, depression, and fatigue. There was a similar significant relationship between caregiver report of child’s QOL (HOQ) and caregiver assessment of the child’s posttraumatic stress symptoms as well as their assessment of burden of care (rho = −0.59 and rho = −0.51, respectively). No relationship between parent-reported HOQ and child-reported psychosocial factors was significant. No clinical or demographic variables were associated with child self-assessed cHOQ.CONCLUSIONSPediatric patients with hydrocephalus consistently rate their own QOL higher than their caregivers do. Psychological factors such as anxiety and posttraumatic stress may be associated with lower QOL. These findings warrant further exploration.

Maternal prenatal anxiety and child brain-derived neurotrophic factor (BDNF) genotype: Effects on internalizing symptoms from 4 to 15 years of age

Development and Psychopathology ◽

10.1017/s095457941400100x ◽

2014 ◽

Vol 26 (4pt2) ◽

pp. 1255-1266 ◽

Cited By ~ 31

Author(s):

Kieran J. O'Donnell ◽

Vivette Glover ◽

Joanna D. Holbrook ◽

Thomas G. O'Connor

Keyword(s):

Neurotrophic Factor ◽

Internalizing Symptoms ◽

Brain Derived Neurotrophic Factor ◽

Maternal Anxiety ◽

Individual Vulnerability ◽

Prenatal Anxiety ◽

Parents And Children ◽

Gene Environment ◽

Strengths And Difficulties ◽

AbstractMultiple behavioral and health outcomes, including internalizing symptoms, may be predicted from prenatal maternal anxiety, depression, or stress. However, not all children are affected, and those that are can be affected in different ways. Here we test the hypothesis that the effects of prenatal anxiety are moderated by genetic variation in the child's brain-derived neurotrophic factor (BDNF) gene, using the Avon Longitudinal Study of Parents and Children population cohort. Internalizing symptoms were assessed from 4 to 13 years of age using the Strengths and Difficulties Questionnaire (n = 8,584); a clinical interview with the adolescents was conducted at age 15 years (n = 4,704). Obstetric and psychosocial risk and postnatal maternal symptoms were included as covariates. Results show that prenatal maternal anxiety predicted internalizing symptoms, including with the diagnostic assessment at 15 years. There was a main effect of two BDNF polymorphisms (rs6265 [val66met] and rs11030104) on internalizing symptoms up to age 13. There was also genetic moderation of the prenatal anxiety effect by different BDNF polymorphisms (rs11030121 and rs7124442), although significant effects were limited to preadolescence. The findings suggest a role for BDNF gene–environment interactions in individual vulnerability to the effects of prenatal anxiety on child internalizing symptoms.

Hubungan Pengetahuan dengan Kecemasan Ibu Pasca Imunisasi DPT Anaknya di Kelurahan Kolakaasi

Jurnal Surya Medika ◽

10.33084/jsm.v5i2.1292 ◽

2020 ◽

Vol 5 (2) ◽

pp. 65-74

Author(s):

Bangu Bangu ◽

Yuhanah Yuhanah

Keyword(s):

Infectious Diseases ◽

Maternal Anxiety ◽

Survey Method ◽

Test Results ◽

Immunization Programs ◽

Cross Sectional ◽

Knowledge Questionnaire ◽

Anxiety Levels ◽

The Government

Immunization is an injection of immunity against certain diseases. The disease is avoided by means of a complete basic immunization in infants before 1 year of age. A report from the section on eradicating infectious diseases in the Ministry of Health in Indonesia has decreased the number of people who can be prevented by immunization programs. The success of this program is the collaboration between the immunizers and Posyandu cadres supported by the government and awareness from the community. Ignorance of mothers about DPT immunization is a major cause of anxiety in mothers after DPT immunization in their children. The materials and methods used were knowledge questionnaire sheets and maternal anxiety levels. This type of research is an analytic survey. The survey method uses cross-sectional. The population was 183 mothers as respondents. The results obtained by knowledge of high category mothers while anxiety categories are low. Analysis of the data with the Spearman Rho technique, the results obtained were 0.658 significant. Towards 0.01. Test results get = 0,000 means there is a significant relationship between knowledge and anxiety. Conclusion: The higher the knowledge, the lower the anxiety level of mothers after immunizing the DPT to their children in the Kolakaasi Village.

Early Detection of Neurological Disorders Using Machine Learning Systems - Advances in Medical Technologies and Clinical Practice ◽

Linguistic Markers in Individuals With Symptoms of Depression in Bi-Multilingual Context

10.4018/978-1-5225-8567-1.ch012 ◽

2019 ◽

pp. 216-240

Author(s):

Anbu Savekar ◽

Shashikanta Tarai ◽

Moksha Singh

Keyword(s):

Mental Illness ◽

Emotional Health ◽

Psychological Process ◽

Function Words ◽

Linguistic Markers ◽

Symptoms Of Depression ◽

Stigma Of Mental Illness ◽

Verbal Content ◽

Linguistic Behavior ◽

Depression has been identified as the most prevalent mental disorder worldwide. Due to the stigma of mental illness, the population remains unidentified, undiagnosed, and untreated. Various studies have been carried out to detect and track depression following symptoms of dichotomous thinking, absolutist thinking, linguistic markers, and linguistic behavior. However, there is little study focused on the linguistic behavior of bilingual and multilingual with anxiety and depression. This chapter aims to identify the bi-multilingual linguistic markers by analyzing the recorded verbal content of depressive discourse resulting from life situations and stressors causing anxiety, depression, and suicidal ideation. Different contextual domains of word usage, content words, function words (pronouns), and negative valance words have been identified as indicators of psychological process affecting cognitive behavior, emotional health, and mental illness. These findings are discussed within the framework of Beck's model of depression to support the linguistic connection to mental illness-depression.

Assessment of family function impact on depression severity among infertile women attending a teaching hospital in South-South Nigeria

Future Science OA ◽

10.2144/fsoa-2020-0033 ◽

2020 ◽

Vol 6 (8) ◽

pp. FSO595

Author(s):

Alex A Adelosoye ◽

Olumuyiwa J Fasipe ◽

Elihu I Medunoye ◽

Onyekachukwu C Adelosoye ◽

Elisha O Sunday

Keyword(s):

Teaching Hospital ◽

Severe Depression ◽

Family Dysfunction ◽

University Teaching ◽

Depression Severity ◽

Family Function ◽

Severity Of Depression ◽

Husband Support ◽

The Impact

Aim: Family function and husband support can impact depression severity in women with infertility disorder. The aim of this study was to assess the impact of family function and husband support on depression severity among women with infertility disorder at the fertility clinics of a University Teaching Hospital, South-South, Nigeria. Methodology: A cross-sectional descriptive study was carried out among 341 female respondents attending the University of Benin Teaching Hospital fertility clinics over a 3-month period, using a semistructured interviewer administered questionnaire. Data obtained were analyzed. Result: Respondents mean age was 36 ± 5.3 years. The overall prevalence for depression in this study was 42.5% with a breakdown of 64.2%, 30.4% and 5.4% of these depressed participants having mild, moderate and severe depression, respectively. Family dysfunction had a statistically significant relationship with severity of depression in women with infertility (p < 0.001). A statistically significant relationship was established between poor husband support and the severity of depression (p < 0.001). Conclusion: Depression is highly prevalent among women with infertility disorder, severe depression was associated with family dysfunction. Good family function would reduce the severity of depression.

Comparison of Perception of Pregnancy Risk of Nulliparous Women of Advanced Maternal Age and Younger Age

Journal of Midwifery & Women s Health ◽

10.1111/j.1542-2011.2012.00188.x ◽

2012 ◽

Vol 57 (5) ◽

pp. 445-453 ◽

Cited By ~ 31

Author(s):

Hamideh Bayrampour ◽

Maureen Heaman ◽

Karen A. Duncan ◽

Suzanne Tough

Keyword(s):

Maternal Age ◽

Advanced Maternal Age ◽

Pregnancy Risk ◽

Nulliparous Women ◽

Younger Age

Mother-Infant Emotion Regulation at Three Months: The Role of Maternal Anxiety, Depression and Parenting Stress

Psychopathology ◽

10.1159/000446811 ◽

2016 ◽

Vol 49 (4) ◽

pp. 285-294 ◽

Cited By ~ 26

Author(s):

Cristina Riva Crugnola ◽

Elena Ierardi ◽

Valentino Ferro ◽

Marcello Gallucci ◽

Cinzia Parodi ◽

...

Keyword(s):

Emotion Regulation ◽

Parenting Stress ◽

Maternal Anxiety ◽

Timing of the Initiation of Hydroxyurea and Hematologic Outcomes in Patients with Sickle Cell Disease (SCD)

Blood ◽

10.1182/blood.v120.21.1004.1004 ◽

2012 ◽

Vol 120 (21) ◽

pp. 1004-1004

Author(s):

Shaina Willen ◽

Nirmish Shah ◽

Courtney Thornburg ◽

Jennifer Rothman

Keyword(s):

Sickle Cell Disease ◽

Sickle Cell ◽

Medical Center ◽

Fetal Hemoglobin ◽

Clinical Severity ◽

Cell Disease ◽

Younger Age ◽

The Mean

Abstract Abstract 1004 Hydroxyurea (HU) is approved for use in adults with Sickle Cell Disease (SCD) and increases the production of fetal hemoglobin (HbF). Increased HbF is associated with decreased clinical severity in adults and children with SCD, such as decreased numbers of vaso-occlusive events, transfusions, and hospitalizations. Higher HbF at initiation of HU is predictive of HbF response, but association between age of hydroxyurea initiation and HbF response has not been investigated. We hypothesize that starting hydroxyurea at an early age may improve hematological and clinical response. In order to determine if younger age at hydroxyurea initiation affects the percentage of HbF achieved with hydroxyurea, we conducted a retrospective cohort study. We identified subjects enrolled in the Duke University Medical Center Comprehensive Sickle Cell program who initiated hydroxyurea when they were less than 17.99 years of age and were prescribed hydroxyurea for at least six months. The following data were abstracted from the medical record between December 1996 and April 2011: age, hemoglobin, percentage HbF, and mean corpuscular volume (MCV) at start of HU and at maximum tolerated dose (MTD) of HU therapy. The correlation coefficient and p-values for various parameters were calculated. Seventy-three patients (41 males and 32 females) were included in the analysis. The mean age at hydroxyurea initiation was 5.5 years (1.2–14.1). The mean hydroxyurea dose at MTD was 28.6 ± 3.2 mg/kg/day. At initiation, the mean hemoglobin was 8.2 ± 1.2 g/dL, the mean MCV was 83±7.4 fl and mean HbF was 10 ± 5.7%. At MTD, the mean hemoglobin was 9.4 ± 1.1 g/dL, the mean MCV was 99 ± 11.1 fl, and the mean HbF was 21.7 ± 9.4%. As expected, at MTD, an elevated MCV was correlated with elevated fetal hemoglobin (r2= 0.19, p= 0.0001) [Table 1]. There was a statistically significant relationship between the age at HU initiation and the HbF at MTD (r2= 0.08, p= 0.015) [Figure 1] as well as the age at HU initiation and the hemoglobin at MTD (r2= 0.19, p= 0.016). The relationship between the age at starting HU and the overall change in HbF (DHbF) was not statistically significant (r2= 0.01, p= 0.41). There was not a statistically significant relationship between age at HU initiation and the MTD of HU (r2= 0.003, p= 0.61). The 6 patients started on HU at age less than 2 years (mean 1.5 ± 0.3 years) maintained a mean elevated HbF of 19.1 ± 5% at last documented follow-up with follow-up ranging from 1.4–13 year of uninterrupted hydroxyurea use. Starting hydroxyurea therapy at a younger age appears to improve HbF response as measured at MTD, although there is variability in the level of fetal hemoglobin attained. There is not an association seen with the DHbF or dose at MTD and age at hydroxyurea initiation. In summary, starting hydroxyurea at a younger age, when HbF is >20%, leads to persistence of HbF production and overall improvement in hematological efficacy. This was not simply the result of achieving MTD at a younger age before physiologic decline of HbF. Disclosures: Off Label Use: Hydroxyurea for complications of sickle cell disease in pediatrics. Shah:Eisai: Research Funding; Adventrx: Consultancy.