scholarly journals THE EVALUATION OF EFFECT OF VARIOUS OUTCOMES OF KIDNEY TRANSPLANTATION SURGERY ON ECONOMIC COSTS UNDER TREATMENT OF KIDNEYS CHRONIC DISEASE

2019 ◽  
Vol 62 (2) ◽  
pp. 60-67
Author(s):  
I. A. Lakman ◽  
A. A. Khalikova ◽  
Alexey A. Korzhenevskiy
Keyword(s):  
Kidney Transplantation ◽  
Human Life ◽  
Positive Outcome ◽  
Economic Losses ◽  
Economic Costs ◽  
Actual Problem ◽  
Transplantation Surgery ◽  
Number Of Patients ◽  
Heavy Burden ◽  
The Given

The growth of number of patients suffering with chronic kidneys disease became a reverse side of increasing of population life-span during recent decades. The treatment of the given pathology places a heavy burden on state economics. Nowadays, the implementation of kidneys transplantation is the main and only one mode of treatment of this disease permitting both to prolong human life and to significantly ameliorate its quality. The actual problem is the evaluation of economic costs occurring under both successful and unsuccessful outcomes of transplantation. The last one results in returning patient to dialysis procedure. The assessment was applied to direct and indirect expenses of kidney transplantation surgery and post-operational monitoring of patient, including application of dialysis. The expenses of treatment of patient with chronic kidneys disease per one person made annually up to: 1 266 967,88 rubles using dialysis therapy; 1 665 110,19 rubles using transplantation with positive outcome; 2 922 078,07 rubles using transplantation with unsuccessful outcome. Besides, in case of unsuccessful outcome of transplantation total amount of economic losses increased more on 91 343,77 rubles annually at the expense of decreasing of tax levy and increasing of disability compensation.

scholarly journals THE SEPSIS-INDUCED ENCEPHALOPATHY

2018 ◽  
Vol 24 (2) ◽  
pp. 99-103
Author(s):  
Sofiya M. Rhalib ◽  
S. V Sviridov ◽  
I. V Vedenina ◽  
V. S Nekrasova
Keyword(s):  
Amino Acids ◽  
Metabolic Disorders ◽  
Aromatic Amino Acids ◽  
Diagnostic Techniques ◽  
Disorder Of Consciousness ◽  
Actual Problem ◽  
Consciousness Level ◽  
Number Of Patients ◽  
Sleep Deficiency ◽  
The Given

The article presents a review of publications concerning sepsis-induced encephalopathy. The sepsis-induced encephalopathy is a disorder of cognitive functions frequently occurring in sepsis without any relationship with inflammation central nervous system. This condition is an actual problem against the background of increasing of number of patients with infection and sepsis. The main pathophysiologic mechanism of sepsis-induced encephalopathy is considered derangement of hematoencephalic barrier and also increasing of concentration of aromatic amino acids. The clinical symptomatic of hematoencephalic barrier is characterized by disorder of consciousness level and also by disorders of sleep, deficiency of attention, delirium down to coma. To confirm diagnosis of sepsis-induced encephalopathy various diagnostic scales are applied and instrumental and laboratory diagnostic techniques. In treatment of the given pathology key positions are elimination of infection and correction of metabolic disorders.

FEATURES OF PSYCHO-EMOTIONAL STATUS IN TUBERCULOSIS PATIENTS

2021 ◽  
pp. 169-173
Author(s):  
Ольга Сергеевна Мартышова ◽  
Ольга Викторовна Великая ◽  
Наталья Сергеевна Петрова ◽  
Софья Алексеевна Корчагина
Keyword(s):  
Psychological Assessment ◽  
Emotional Reactions ◽  
Emotional Status ◽  
Behavioral Reactions ◽  
Actual Problem ◽  
Tuberculosis Patients ◽  
Number Of Patients ◽  
Heavy Burden ◽  
The Russian Federation ◽  
Early Detection And Prevention

Целью работы стало изучение особенностей психоэмоционального статуса больных туберкулезом. По данным ВОЗ треть населения земного шара инфицировано микобактериями туберкулеза. Ежегодно заболевают туберкулезом 10 млн. человек, умирают от туберкулеза 1.2 млн. В настоящее время в результате проведения мероприятий по раннему выявлению и профилактике, эпидемиологическая ситуация по туберкулезу в России улучшается. Но Российская Федерация все еще входит в число 18 стран с тяжелым бременем по туберкулезу, продолжается увеличиваться количество больных с МЛУ и ШЛУ - туберкулезом во всем мире. Актуальной проблемой фтизиатрической практики является психологическая оценка больного туберкулезом своего же состояния, от этого напрямую зависит желание проходить курс лечения. У пациентов с установленным диагнозом- туберкулез, отмечаются специфические эмоциональные реакции на заболевание, часто выступающие как психотравмирующий фактор, вплоть до развития пограничных психических нарушений. Известно, что восприятие заболевания, а так же формирование внутренней картины болезни в итоге приводит к расстройству адаптации и формированию новых поведенческих реакций, от которых зависит эффективность лечения и реабилитации. Закономерности формирования картины болезни, а также различные типы психического реагирования человека на своё заболевание сочетаются в клинике со специфическими особенностями психического состояния пациентов, характером реагирования на ее течение, успешность лечения и, как следствие, исход The aim of the work was to study the peculiarities of the psychoemotional status of patients with tuberculosis. According to who, a third of the world's population is infected with Mycobacterium tuberculosis. Every year, 10 million people get sick with tuberculosis, 1.2 million die from tuberculosis. Currently, as a result of measures for early detection and prevention, the epidemiological situation of tuberculosis in Russia is improving. But the Russian Federation is still among the 18 countries with a heavy burden of tuberculosis, and the number of patients with MDR and XDR - TB worldwide continues to increase. An actual problem of phthisiological practice is the psychological assessment of a patient with tuberculosis of his own condition, the desire to undergo treatment directly depends on this. In patients with an established diagnosis of tuberculosis, specific emotional reactions to the disease are noted, often acting as a psychotraumatic factor, up to the development of borderline mental disorders. It is known that the perception of the disease, as well as the formation of an internal picture of the disease, eventually leads to a disorder of adaptation and the formation of new behavioral reactions on which the effectiveness of treatment and rehabilitation depends. Regularities of formation of the clinical picture, as well as various types of mental response of a person with their disease combined in the clinic with the specific features of the mental state of patients, the nature of response to its current, successful treatment and, as a consequence, the outcome

SEISMIC RISK AND RESILIENCE ASSESSMENT OF INDUSTRIAL FACILITIES: CASE STUDY ON A BLACK CARBON PLANT

2020 ◽  
Author(s):  
George Karagiannakis
Keyword(s):  
Seismic Risk ◽  
Numerical Models ◽  
Fragility Curves ◽  
Human Life ◽  
Mitigation Strategies ◽  
Economic Losses ◽  
Risk And Resilience ◽  
Industrial Plants ◽  
Plant Equipment

This paper deals with state of the art risk and resilience calculations for industrial plants. Resilience is a top priority issue on the agenda of societies due to climate change and the all-time demand for human life safety and financial robustness. Industrial plants are highly complex systems containing a considerable number of equipment such as steel storage tanks, pipe rack-piping systems, and other installations. Loss Of Containment (LOC) scenarios triggered by past earthquakes due to failure on critical components were followed by severe repercussions on the community, long recovery times and great economic losses. Hence, facility planners and emergency managers should be aware of possible seismic damages and should have already established recovery plans to maximize the resilience and minimize the losses. Seismic risk assessment is the first step of resilience calculations, as it establishes possible damage scenarios. In order to have an accurate risk analysis, the plant equipment vulnerability must be assessed; this is made feasible either from fragility databases in the literature that refer to customized equipment or through numerical calculations. Two different approaches to fragility assessment will be discussed in this paper: (i) code-based Fragility Curves (FCs); and (ii) fragility curves based on numerical models. A carbon black process plant is used as a case study in order to display the influence of various fragility curve realizations taking their effects on risk and resilience calculations into account. Additionally, a new way of representing the total resilience of industrial installations is proposed. More precisely, all possible scenarios will be endowed with their weighted recovery curves (according to their probability of occurrence) and summed together. The result is a concise graph that can help stakeholders to identify critical plant equipment and make decisions on seismic mitigation strategies for plant safety and efficiency. Finally, possible mitigation strategies, like structural health monitoring and metamaterial-based seismic shields are addressed, in order to show how future developments may enhance plant resilience. The work presented hereafter represents a highly condensed application of the research done during the XP-RESILIENCE project, while more detailed information is available on the project website https://r.unitn.it/en/dicam/xp-resilience.

scholarly journals COVID-19—Importance for Patients on the Waiting List and after Kidney Transplantation—A Single Center Evaluation in 2020–2021

Pathogens ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 429
Author(s):  
Simone C. Boedecker ◽  
Pascal Klimpke ◽  
Daniel Kraus ◽  
Stefan Runkel ◽  
Peter R. Galle ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
Waiting List ◽  
Smoking History ◽  
Immunocompromised Patients ◽  
Dialysis Patients ◽  
Vaccination Programs ◽  
Mild Disease ◽  
Probability Of Survival ◽  
Number Of Patients ◽  
Immunosuppressed Patients

(1) Background: Dialysis patients and recipients of a kidney allograft are at high risk for infection with SARS-CoV-2. It has been shown that the development of potent neutralizing humoral immunity against SARS CoV-2 leads to an increased probability of survival. However, the question of whether immunocompromised patients develop antibodies has not yet been sufficiently investigated; (2) Methods: SARS-CoV-2 antibodies were examined in hemodialysis patients on the waiting list for kidney transplantation as well as patients after kidney transplantation. Patients were interviewed about symptoms and comorbidities, BMI, and smoking history; (3) Results: SARS-CoV-2 antibodies were found in 16 out of 259 patients (6%). The trend of infections here reflects the general course of infection in Germany with a peak in November/December of 2020. Remarkably, patients on the waiting list experienced only mild disease. In contrast, transplanted patients had to be hospitalized but recovered rapidly from COVID-19. Most interesting is that all immunosuppressed patients developed antibodies against SARS-CoV-2 after infection; (4) Conclusions: Even with extensive hygiene concepts, an above-average number of patients were infected with SARS-CoV-2 during the second wave of infections in Germany. Because SARS-CoV-2 infection triggered the formation of antibodies even in these immunocompromised patients, we expect vaccination to be effective in this group of patients. Thus, dialysis patients and patients after kidney transplantation should be given high priority in vaccination programs.

scholarly journals Continuous exposure to ambient air pollution and chronic diseases: prevalence, burden, and economic costs

2020 ◽  
Vol 35 (4) ◽  
pp. 379-399
Author(s):  
Seyed M. Karimi ◽  
Ali Maziyaki ◽  
Samaneh Ahmadian Moghadam ◽  
Mahtab Jafarkhani ◽  
Hamid Zarei ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Air Pollution ◽  
Chronic Diseases ◽  
Ambient Air ◽  
Ambient Air Pollution ◽  
Economic Losses ◽  
Continuous Exposure ◽  
Economic Costs ◽  
Unit Change ◽  
Data Limitations

AbstractStudies that assess the connection between the prevalence of chronic diseases and continuous exposure to air pollution are scarce in developing countries, mainly due to data limitations. Largely overcoming data limitations, this study aimed to investigate the association between the likelihood of reporting a set of chronic diseases (diabetes, cancer, stroke and myocardial infarction, asthma, and hypertension) and continuous exposure to carbon monoxide (CO), nitrogen dioxide (NO2), ozone (O3), and coarse particulate matter (PM10). Using the estimated associations, the disease burden and economic costs of continuous exposure to air pollutants were also approximated. A 2011 Health Equity Assessment and Response Tool survey from Tehran, Iran, was used in the main analyses. A sample of 67,049 individuals who had not changed their place of residence for at least 2 years before the survey and reported all relevant socioeconomic information was selected. The individuals were assigned with the average monthly air pollutant levels of the nearest of 16 air quality monitors during the 2 years leading to the survey. Both single- and multi-pollutant analyses were conducted. The country’s annual household surveys from 2002 to 2011 were used to calculate the associated economic losses. The single-pollutant analysis showed that a one-unit increase in monthly CO (ppm), NO2 (ppb), O3 (ppb), and PM10 (μg/m3) during the 2 years was associated with 751 [confidence interval (CI): 512–990], 18 (CI: 12–24), 46 (CI: −27–120), and 24 (CI: 13–35) more reported chronic diseases in 100,000, respectively. The disease-specific analyses showed that a unit change in average monthly CO was associated with 329, 321, 232, and 129 more reported cases of diabetes, hypertension, stroke and myocardial infarction, and asthma in 100,000, respectively. The measured associations were greater in samples with older individuals. Also, a unit change in average monthly O3 was associated with 21 (in 100,000) more reported cases of asthma. The multi-pollutant analyses confirmed the results from single-pollutant analyses. The supplementary analyses showed that a one-unit decrease in monthly CO level could have been associated with about 208 (CI: 147–275) years of life gained or 15.195 (CI: 10.296–20.094) thousand US dollars (USD) in life-time labor market income gained per 100,000 30-plus-year-old Tehranis.

scholarly journals High-resolution analysis of 1 day extreme precipitation in Sicily

2015 ◽  
Vol 15 (10) ◽  
pp. 2347-2358 ◽  
Author(s):  
M. Maugeri ◽  
M. Brunetti ◽  
M. Garzoglio ◽  
C. Simolo
Keyword(s):  
High Resolution ◽  
Extreme Precipitation ◽  
Human Life ◽  
Extreme Value Distribution ◽  
Generalized Extreme Value Distribution ◽  
Return Level ◽  
Regional Frequency Analysis ◽  
Economic Losses ◽  
Data Set ◽  
High Quantiles

Abstract. Sicily, a major Mediterranean island, has experienced several exceptional precipitation episodes and floods during the last century, with serious damage to human life and the environment. Long-term, rational planning of urban development is indispensable to protect the population and to avoid huge economic losses in the future. This requires a thorough knowledge of the distributional features of extreme precipitation over the complex territory of Sicily. In this study, we perform a detailed investigation of observed 1 day precipitation extremes and their frequency distribution, based on a dense data set of high-quality, homogenized station records in 1921–2005. We estimate very high quantiles (return levels) corresponding to 10-, 50- and 100-year return periods, as predicted by a generalized extreme value distribution. Return level estimates are produced on a regular high-resolution grid (30 arcsec) using a variant of regional frequency analysis combined with regression techniques. Results clearly reflect the complexity of this region, and show the high vulnerability of its eastern and northeastern parts as those prone to the most intense and potentially damaging events.

Ice jam mitigation

1990 ◽  
Vol 17 (5) ◽  
pp. 675-685 ◽  
Author(s):  
Harold S. Belore ◽  
Brian C. Burrell ◽  
Spyros Beltaos
Keyword(s):  
Key Words ◽  
Carrying Capacity ◽  
Flood Control ◽  
Human Life ◽  
Water Levels ◽  
Economic Losses ◽  
River Ice ◽  
Ice Jams ◽  
Ice Jam ◽  
Ice Breakup

In Canada, flooding due to the rise in water levels upstream of an ice jam, or the temporary exceedance of the flow and ice-carrying capacity of a channel upon release of an ice jam, has resulted in the loss of human life and extensive economic losses. Ice jam mitigation is a component of river ice management which includes all activities carried out to prevent or remove ice jams, or to reduce the damages that may result from an ice jam event. This paper presents a brief overview of measures to mitigate the damaging effects of ice jams and contains a discussion on their application to Canadian rivers. Key words: controlled ice breakup, flood control, ice jams, ice management, river ice.

scholarly journals Consulta de enfermagem no pré e pós-operatório de transplante renal: faz a diferença?

2009 ◽  
Vol 3 (2) ◽  
pp. 237
Author(s):  
Adriana Valongo Zani ◽  
Giovana Paz ◽  
Glaucimara Boniotti
Keyword(s):  
Renal Failure ◽  
Kidney Transplantation ◽  
Data Collection ◽  
Kidney Transplant ◽  
Professional Practice ◽  
Thematic Analysis ◽  
Descriptive Study ◽  
Qualitative Approach ◽  
Number Of Patients ◽  
Random Draw

ABSTRACTObjective: to describe the patient’s knowledge with chronic renal failure submitted to kidney transplantation on the importance of consultation with nursing for his treatment. Methodology: this is about an exploratory-descriptive study from qualitative approach. The data collection was from January to December 2007. The sample consisted of 36 patients undergoing kidney transplant from a total of 400. For the choice of the patients was a random draw simple daily. For data collection was used a questionnaire consisting of 11 questions concerning the information about the kidney transplant. For organization of the results was used thematic analysis proposed by Minayo. Results: as for nursing consultation for a significant number of patients claiming to be of importance to them, since they make them safer, take your questions and will be better targeted.  Conclusion: confirming the effectiveness of professional practice of nurses in the monitoring of renal patients who is subject to renal transplantation. Descriptors: nursing; kidney transplantation; chronic renal failure.RESUMOObjetivo: descrever o conhecimento do paciente portador de insuficiência renal crônica submetido a transplante renal referente à importância da consulta de enfermagem para seu tratamento. Metodologia: tratou-se de um estudo descritivo-exploratório com abordagem qualitativa. O período de coleta foi de janeiro a dezembro de 2007. A amostra foi constituída por 36 pacientes submetidos a transplante renal de um total de 400. Para a escolha dos pacientes foi realizado um sorteio aleatório simples diário. Para a coleta de dados foi utilizado um questionário composto por 11 perguntas referentes as informações sobre o transplante renal. Para organização dos resultados foi utilizada a análise temática proposta por Minayo. Resultados: quanto à consulta de enfermagem um número significativo de pacientes afirmam ser de importância aos mesmos, uma vez que os tornam mais seguros, tiram suas dúvidas e  serão melhor orientados. Conclusão: estes dados vêm a confirmar a eficácia da atuação profissional do enfermeiro no acompanhamento dos pacientes renais que se submeterão ao transplante renal. Descritores: enfermagem; transplante renal; insuficiência renal crônica.RESUMENObjetivo: describir el conocimiento del paciente portador de insuficiência renal crónica sometido a transplante renal, referente a la importáncia de la consulta de enfermería para su tratamiento. Metodologia: studio exploratório y descriptivo con abordaje cualitativa. El período de recogida fue de enero a diciembre de 2007. La muestra consistió de 36 pacientes sometidos a trasplante de riñón de un total de 400. Para la elección de los pacientes fue de un sorteo aleatorio simple diario. Para la recogida de datos se utilizó un cuestionario de 11 preguntas relativas a la información sobre el trasplante de riñón. Para la organización de los resultados se utilizó el análisis temático propuesto por Minayo. Resultados: cuanto a consulta de enfermeria, un número significativo de pacientes, afirma ser de importância a los mismos, una vez que los hacen mas seguros, disipan sus dudas y serán mejor orientados. Conclusión: lo que confirma la eficácia de la actuación profesional del enfermero, en el acompañamiento de los pacientes renales que se sometieron al transplante renal. Descriptores: enfermería; transplante renal; insuficiéncia renal crónica.

FC 117TIME TRENDS IN PROBABILITY OF STARTING HOME DIALYSIS OVER A 20 YEAR PERIOD: A DUTCH REGISTRY STUDY

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Anna Bonenkamp ◽  
Tiny Hoekstra ◽  
Marc Hemmelder ◽  
Anita Van Eck van der Sluijs ◽  
Alferso C Abrahams ◽  
...  
Keyword(s):  
Kidney Transplantation ◽  
The Netherlands ◽  
Risk Model ◽  
The Elderly ◽  
Dialysis Patients ◽  
Dialysis Treatment ◽  
Home Dialysis ◽  
System Utilization ◽  
Number Of Patients ◽  
Kidney Transplantations

Abstract Background and Aims A growing number of patients suffers from End Stage Kidney Disease(ESKD), causing a logistical and economic burden to the healthcare system. Utilization of home dialysis is low in many countries worldwide, although home dialysis has several advantages including higher quality of life and possibly lower costs. The aim of this study is to explore time trends in the use of home dialysis in the Netherlands. Method Anonymized registry data from the Dutch Renal Registry (RENINE) were used for this study. All dialysis episodes of adult patients who started dialysis treatment between 1997 through 2016 in the Netherlands were included, including those who previously underwent kidney transplantation. Dialysis episodes shorter than 90 days were excluded. The probability of starting home dialysis between 1997 through 2016 was evaluated in time periods of 5 years, using logistic regression analysis. Home dialysis was defined as start with peritoneal dialysis or home haemodialysis, or transfer to either within 2 years after dialysis start. A logistic multilevel model was used to adjust for clustering at patient level. The cumulative incidence function of start of home dialysis in incident patients was estimated with a competing risk model with recovery of kidney function, kidney transplantations, and all-cause mortality as competing events. All analyses were stratified for age categories at dialysis start: 20-44 years, 45-64 years, 65-74 years and ≥75 years. Results A total of 33,340 dialysis episodes in 31,569 patients were evaluated. Between 1997 and 2016, mean age at start of dialysis treatment increased from 62.5±14.0 to 65.5±14.5 years in in-centre haemodialysis patients, whereas it increased from 51.9±15.1 to 62.5±14.6 years in home dialysis patients. In patients < 65 years, the probability of starting home dialysis was significantly lower during each 5-year period compared to the previous period, and kidney transplantation occurred more often. In patients ≥ 65 years, incidence of home dialysis remained constant, whereas mortality decreased. Conclusion In patients < 65 years, the overall probability of starting home dialysis declined consistently over the past 20 years. The age of home dialysis patients increased more rapidly than that of in-centre dialysis patients, implying that pre-dialysis education and organization of home dialysis must be adapted to the needs of the elderly patient. These developments have a significant impact on the organisation of home dialysis for patients with ESKD.

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