scholarly journals Correlation between Hemoglobin Reticulocytes and Ferritin in Chronic Kidney Disease Patients Undergoing Hemodialysis at PKU Bantul

2021 ◽  
Vol 17 (2) ◽  
pp. 133
Author(s):  
Muhammad Salman Shalahuddin ◽  
Linda Rosita

Abstract: As many as 7 – 12% of the world's population has chronic kidney disease (CKD). CKD patients can experience various complications, one of which is anemia. Anemia can cause a variety of cardiovascular complications in CKD patients. Enforcement of the diagnosis of anemia and its type is carried out by laboratory examination, among others by examination of reticulocytes-hemoglobin (ret-he) and iron status such as serum ferritin. Examination of these parameters can help in planning the right treatment for CKD patients who have anemia. The purpose of this study was to determine the relationship of Ret-he with ferritin levels in CKD patients undergoing hemodialysis at PKU Bantul Hospital. This study used cross-sectional method. The data source used was secondary data obtained from medical records and the Indonesian Renal Registry (IRR). Sampling research used consecutive sampling method. The analysis used univariate analysis which was frequency distribution table, and bivariate analysis. Univariate analysis obtained that average levels of ret-he from 50 subjects was 28.87 ± 3.75 pg and median serum ferritin levels were 118,1 (9,76 – 1615) mL. Bivariate analysis with pearson correlation test found a significant correlation between serum ret-he and ferritin levels (r = 0.498, p = 0.000).There was a significant correlation between he-ret levels and serum ferritin levels Keywords: chronic kidney disease, anemia, reticulocytes-hemoglobin, serum ferritin.

2021 ◽  
Vol 15 (2) ◽  
pp. 58
Author(s):  
Gilang Fitra Dininta ◽  
Dessy Hermawan ◽  
Ringgo Alfarisi ◽  
Achmad Farich

<em>Dengue hemorrhagic fever (DHF) case in Bandar Lampung City shows an increasing trend of cases. In 2014, the number of cases was 389 cases; by the end of 2018, it had increased to 1,114 cases. Climatic factors are thought to have contributed to the increase in cases. This study aims to determine the relationship between climate factors and the number of dengue cases in 2015-2019. The study used secondary data with a cross-sectional design. Data were obtained from the Bandar Lampung City Health Office and the Meteorology, Climatology, and Geophysics Agency (BMKG). Univariate analysis with Mean, Median, Minimum-Maximum. The Kolmogorov-Smirnov test was carried out to determine the normality of the data, followed by bivariate analysis with Pearson Correlation and Spearman's Rank. Multivariate analysis was performed with Linear Regression by considering the regression assumption. The study found that more dengue cases were in January, February, March. A negative correlation was shown between temperature and the incidence of DHF (r=-0.274; p-value=0.038), and a positive correlation with humidity (r=0.390; p-value=0.002), and rainfall (r=0.370; p-value= 0.005). Air humidity and rainfall affect the number of dengue cases, respectively 33.0% and 30.5%. The results of this study have provided evidence of a relationship between climate factors and cases of DHF. It is hoped that this can be an input for the prevention and control of dengue fever.</em>


Author(s):  
Agri Febria Sari ◽  
Rikarni Rikarni ◽  
Deswita Sari

Reticulocyte hemoglobin equivalent (RET-He) represents hemoglobin content in reticulocyte. Reticulocyte hemoglobin equivalent test can be used to asses iron status of chronic kidney disease (CKD). Iron deficiency happens in 40% CKD and could lead to anemia manifestation. Level of RET-He gives real-time assesment of iron availability for hemoglobin production and the level will getting lower when iron storage for erythropoiesis decreasing. Reticulocyte hemoglobin equivalent is more stabil than feritin and transferin saturation in assessing iron status. Aim of this study is to determine RET-He level in patients with CKD stage IV and V. This study is  a cross sectional descripstive study. Subjects were 96 CKD stage IV and V patients that met inclusion and exclusion criterias. Subjects conducted blood tests at Central Laboratory Installation Dr. M. Djamil Hospital Padang from July to September 2020. Examination of RET-He level was analyzed by Sysmex XN-1000 flowcytometry fluorescense method. Data was presented in frequency distribution table. The RET-He level below cutoff (<29,2 pg) indicates the need for iron suplementation therapy for CKD stage IV and V patients. Samples with RET-He level below cutoff were 48 (50%) and 48 (50%) were above cutoff.


2019 ◽  
Vol 50 (1) ◽  
pp. 72-80
Author(s):  
Mary Lynn Davis-Ajami ◽  
Jeffery C. Fink ◽  
Marianne Baernholdt ◽  
Jun Wu

Background: Adverse safety events (ASE) during hospitalization may contribute to renal decline or poor outcomes. Understanding factors contributing to ASE in chronic kidney disease (CKD) is limited. The objective is to compare differences and determine predictors of renal pertinent ASE in discharges for CKD. Method: A cross-sectional analysis of the National Inpatient Sample, Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality 2012 data. The study included adults age ≥18 years with discharge diagnosis for CKD stages 1–4, excluding cancer of the kidney and renal pelvis, renal transplant, end-stage renal disease. Predictors included study sample characteristics, including patient demographics, comorbidity, and hospitalization-related variables. Outcomes assessed included distribution of ASE (angioedema, confusion, muscle weakness or cramps, lower extremity edema (LEE), falls, hypoglycemia, nausea-vomiting-diarrhea (NVD), and skin rash), mean total charge per hospital event, and length-of-stay. The analytical approach used descriptive statistics (means and proportions) and bivariate analysis to compare differences (ASE versus none). Predictors of ASE were explored using multivariate logistic regression. Results: 10.3% of inpatient discharges for CKD showed an ASE. Mean charges (USD 48,072 vs. 46,996), days length-of-stay (6.8 vs. 5.7), number of diagnosis on record (6.8 vs. 5.7), geographical region (Midwest, and West), and type of hospital (rural) were significantly associated with ASE. Most common ASEs were confusion (18%), LEE (21.3%), and NVD (50.7%). Odds of ASE increased for age, female gender, rural hospitals, geographical region, and diagnosis for anemia, coagulopathies, depression, fluid and electrolyte disorders, neurological disorders, psychoses, and weight loss. Conclusions: We identified key factors that increase the risk of ASE in patients with CKD. Opportunities exist to reduce ASE in CKD.


2021 ◽  
Vol 16 (1) ◽  
pp. 14-22
Author(s):  
Urip Tri Wijayanti

Background: The use of modern contraceptives in Central Java tends to decrease while traditional methods are increasing. The purpose of this study was to determine the factors associated with the use of traditional contraceptives among currently married women aged 15-49 in Central Java Province. The factors discussed include the number of children born alive, wife's age, wife's education, wife's occupation, residence, and access/utilization of family planning information sources.Method: The research design was cross-sectional, used secondary data from the Central Java SKAP 2019. The total number of respondents was 2.088 married women aged 15-49 years and not currently pregnant. Data collected by interview using a structured questionnaire. Data analysis with univariate analysis and bivariate analysis using the chi-square statistical test with a significance level of 5%.Results: The research found that most respondents were ≥ 35 years old, having ≥ 2 children, having high education level (senior high school to higher education), not working, living in the cities, and able to use some media to find information about family planning. The related factors to the use of traditional contraceptive methods were education and residences. The number of live birth children, ages, jobs, and the use of media did not influence the use of the traditional contraceptive method.


2021 ◽  
Vol 8 (1) ◽  
pp. 146-151
Author(s):  
Virania Arvianti ◽  
◽  
Septian Septian ◽  
Aturut Yansen ◽  
◽  
...  

IntroductionAnemia is the most common occurrence in chronic kidney disease undergoing hemodialysis therapy. In the condition of chronic kidney disease, the decline in kidney function can occur slowly and chronically until the kidneys do not function at all. Hemodialysis is one of the therapies used to replaced kidney function. During hemodialysis, a decrease in hemoglobin levels often occurs, this is due to the disruption of the hormon erythropoietin. Objective:determine the differences in hemoglobin levels in patients with chronic kidney disease before and after hemodialysis at Bhayangkara TK. I Raden Said SukantoHospital. Method: The design of this research is cross sectional using secondary data and the sampling technique of this research was random sampling with a total of 133 patients. Result: The normality test was carried out first using the Kolmogorov-Smirnova test which showed the results were not normally distributed with a sig value of 0.001. the next test was the Wilcoxon test with a sig (2-tailed_ value of 0.002 with an average hemoglobin level of 8,81 g/dL before hemodialysis and 9,09 g/dL after hemodialysis. Conclusion:Based on the results of the study means that there is a significant difference in a patient with chronic kidney failure before and after hemodialysis.


Author(s):  
Ida Ayu Devi Qirani ◽  
Winda Mulia Ningsih ◽  
Ratu Ayu Dewi Sartika

INTRODUCTION: Underweight is one of the most common forms of undernutrition suffered by children and has implications for both short and long term health problems. Characteristics of children, parents, and environment are factors affecting underweight in children, especially aged 24–59 months. OBJECTIVES: This study aimed to find out the dominant factors affecting underweight in children aged 24–59 months in Java Island. METHODS: This cross-sectional study used secondary data from Indonesia Family Life Survey (IFLS) 2014. There were 1,270 children aged 24–59 months who were involved in this study. We conducted univariate analysis, bivariate analysis using chi-square, and multivariate analysis using binary logistic regression. RESULTS: This study found that 20.2% of children in Java were underweight. Based on bivariate analysis, variables that significantly associated (p <  0.05) with underweight were low birth weight (LBW), acute respiratory infection (ARI), diarrhoea, frequency of eating milk and dairy products, parental education level, and underweight father. Furthermore, based on multivariate analysis, low consumption of milk and dairy products was the dominant factor in this study (OR = 1.80). CONCLUSION: Factors related to underweight can be used to determine appropriate prevention and treatment in community levels, such as by promoting a balanced nutrition program and healthy behaviour.


2020 ◽  
Vol 15 (3) ◽  
pp. 304
Author(s):  
Yuyun Tri Wulansari ◽  
Chatarina Umbul W

Chronic kidney disease is decreasing glomerular filtration rate of less than 15mL/minute which causes someone to undergo a hemodialysis therapy that replaces kidney function. The course of chronic kidney disease is progressive and irreversible and may cause psychological problems in hemodialysis patients such as depression. This study aimed to describe to what extent patients under hemodialysis treatment at Jemursari Hospital, Surabaya experience depression symptoms in patients. This study was descriptive research with a cross-sectional approach. The simple random sampling technique was performed to select 72 patients who had scheduled hemodialysis treatment and been qualified for the inclusion criteria. Data were then analyed using a univariate analysis in variable frequency distribution. The results show that patients with depression symptoms were mostly men as many as 31 people (43.1%), and the majority were aged 46-65 years as many as 24 people (49%).  The latest formal education in most respondents was high school (23.6%). There were 38 respondents (77.5%) who got married, and most respondents were unemployed (77.5%) and had undergone hemodialysis for more than 12 months (77.5%). This study concludes that the patients under hemodialysis treatment at the hospital experienced mild depression symptoms. Keyword: hemodialysis, depression, Beck Depression Inventory.


1970 ◽  
Vol 25 (3) ◽  
pp. 117-120 ◽  
Author(s):  
Md Mahbubur Rahman ◽  
Pradip Kumar Dutta ◽  
Mahmudul Hoque ◽  
Md Iftikher Hossain Han ◽  
Dhiman Banik ◽  
...  

This observational study was done on 52 cases of predialysis chronic kidney disease (CKD) patients with chronic anaemia. The aim of the study was to determine the tissue iron status, comparison of the tissue iron with serum iron profile and justification of giving iron in chronic kidney disease (CKD) patients on the basis of serum iron profile. Bone marrow iron stain was done in each case and compared with the serum iron profile. The mean age of the patients was 46.8 ± 12.6 years and the mean haemoglobin and serum creatinine levels of the study population were 9.36 ± 2.13 gm/dl and 8.0 ± 4.2 mg/dl respectively. Stainable iron deposits were present in 40 (77%) cases. The mean serum ferritin and transferin saturation (TSAT) of the 52 cases were found to be 412.9 ng/ml and 28.3% and that for the 12 iron deficient cases were 101.8 ng/ml and 23.8%. Over all normal (>100ng/ml <500ng/ml), increased (>500ng/ml) or low (>100 ng/ml) serum ferritin was found in 28 and 15 and nine cases respectively. On the other hand, normal (>20% >50%) and low (>20%) TSAT were found in 31 and 12 cases, and high TSAT (>50%) in only nine cases. Out of the 12 cases having no evidence of stainable iron in the marrow low serum ferritin and low TSAT were found in eight (66.6%) and six (50%) cases, and high TSAT and either normal or high serum ferritin in six (50%) & four (33.3%) cases respectively. Low TSAT was also found in six (15%) cases of those having iron deposits in the marrow. It is, therefore, concluded that absence of stainable iron in the bone marrow is a better evidence of iron depletion than the serum iron profile and that serum ferritin and TSAT correlate less well with the bone marrow iron status in patient with chronic kidney disease. (J Bangladesh Coll Phys Surg 2007; 25 : 117-120)


Author(s):  
Rini Mayasari

ABSTRAK WHO memperkirakan diseluruh dunia angka abortus dengan persentase 14-15%. Angka kematian ibu di indonesia tercatat 395/100.000 kelahiran hidup. Penyebab kematian ibu ini salah satunya adalah abortus. Angka kematian ibu akibat abortus yaitu 1,6. Tujuan penelitian ini adalah untuk mengetahui hubungan antara umur dan paritas dengan kejadian abortus inkomplit di RSUD Raden Mattaher Jambi Tahun 2018.Desain penelitian ini menggunakan metode desain penelitian kuantitatif dengan pendekatan cross sectional dimana variabel independen (umur dan paritas) dan variabel dependen (kejadian abortus inkomplit). Populasi dalam penelitian adalah seluruh ibu hamil yang mengalami abortus di RSUD Raden Mattaher Jambi dari bulan Januari sampai dengan bulan November tahun 2018 berjumlah 75 orang dengan dengan sampel penelitian sebanyak 75 orang dengan teknik sampel adalah total populasi, pengumpulan data menggunkan data sekunder. Analisa data yang digunakan adalah analisa univariat menggunakan distribusi frekuensi dan analisa bivariat menggunakan uji Chi-square melalui sistem komputerisasi.Berdasarkan hasil analisa bivariat dengan menggunkan uji statistik Chi-square didapatkan p value pada variabel umur (0,000) dan paritas (0,000) berarti lebih kecil dari α = 0,05. Kesimpulan dari penelitian ini adalah bahwa ada hubungan yang bermakna antara umur dan paritas dengan kejadian abortus inkomplit di RSUD Raden Mattaher Jambi Tahun 2018. Kata Kunci : Kejadian abortus Inkomplit, umur dan paritas   ABSTRACT WHO estimates worldwide abortion rates with a percentage of 14-15%. There are 395 of the mother mortality rate from 100.000 of life birth. One of the cause of mother is abortion. The number of the deaths 1,6 %. The objective of this reseacrh is to know the relationship between age and parity with the incomplete abortion in Regional Public Hospital Raden Mattaher Jambi in 2018. The design of this research uses quantitative research design method with cross sectional approach. The variables are independent ( age and parity) and dependent (incomplete abortion). The population in this research is all of the abortion pregnant women in Regional Public Hospital Raden Mattaher Jambi from January to November 2018 are 75 people with the research samples are 74 people with sample technique called total population. The colleting data is used secondary data. Data analysis is used univariate analysis used frequency distribution and bivariate analysis used uji Chi-square through computerization system. Based on the bivariate analysis with Chi-square concluded p value to age variable (0,001) and parity (0,000) means it is smaller than α = 0,05. The conclusion of this research is to show that there is the meaningful relationship between age and parity and incomplete abortion in Regional Public Hospital Raden Mattaher in 2018. Keywords: The Incomplete Abortion, The Age, and The Parity       


2020 ◽  
Vol 26 (4) ◽  
pp. 183-190
Author(s):  
Theresia Avila Kurnia ◽  
Yanny Trisyani ◽  
Ayu Prawesti

Background: This quantitative study aimed to analyse the relationship between knowledge and nurses' self-confidence (or self-efficacy) in applying palliative care (PC) in the intensive care unit (ICU). This study was a correlational study with a cross-sectional approach. The sampling technique used was total sampling, and the sample included all nurses who were actively working at the general hospital in Bandung, West Java, Indonesia, during the study. There were 127 people in total. Data were collected using questionnaires. The Pearson correlation test was used for bivariate analysis. The results of univariate analysis showed that the majority of respondents had high self-confidence but had less knowledge related to PC in the ICU. Based on the results of the bivariate analysis, there was a significant relationship between knowledge and self-confidence variables. The results showed that a high number of respondents had less knowledge in implementing PC in the ICU. Therefore, familiarisation sessions and training related to this are needed, focusing on nurses' beliefs in their abilities.


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