scholarly journals The Scale of Quantitative Assessment Adherence to Treatment «QAA-25»: Updating of Formulations, Constructive and Factor Validity and a Measure of Consent

2022 ◽  
Vol 17 (6) ◽  
pp. 845-852
Author(s):  
N. A. Nikolaev ◽  
Yu. P. Skirdenko ◽  
A. A. Balabanova ◽  
A. V. Gorbenko ◽  
K. A. Andreev ◽  
...  
Keyword(s):  
Construct Validity ◽  
Lifestyle Modification ◽  
High Reliability ◽  
Internal Validity ◽  
High Sensitivity ◽  
Cross Sectional Study ◽  
Adherence To Treatment ◽  
Cross Sectional ◽  
Adherence Assessment ◽  
Alternative Question

Aim: To update the definitions of selected questions of the "QAA-25" (quantitative adherence assessment) scale and evaluate it according to the criteria of validity and measure of agreement.Materials and Methods. In a descriptive cross-sectional study including 200 patients with coronary heart disease, adherence was determined using traditional and alternative versions of selected questions of the QAA-25 scale, followed by assessment of construct validity, factor validity, and measure of agreement.Results. Alternative question versions did not significantly affect test results, with 81% of respondents in the outpatient sample and 69% in the inpatient sample rating them as "more acceptable." The QAA-25 scale has good construct and internal validity (α – 0.818, αst – 0.832), with moderate agreement (κ – 0.562) and demonstrates high reliability of internal validity – when scale items are consistently excluded, α values remain in the 0.801-0.839 range.Conclusion. The QAA-25 scale with modified question definitions should be used instead of the previous version of the scale. Good construct validity and factor validity, sufficient measure of agreement and specificity, high sensitivity and reliability of the QAA-25 scale allow to recommend it as a tool for assessing adherence to drug therapy, medical support, lifestyle modification and integral adherence to treatment in scientific and clinical practice.

MO864PATIENT MEDICATION ADHERENCE ON HEMODIALYSIS

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Marwa Omrane ◽  
Amel Babchia ◽  
Raja Jaballah ◽  
Afef Mahersia ◽  
Olfa Saidane
Keyword(s):  
Side Effects ◽  
Cross Sectional Study ◽  
Chronic Hemodialysis ◽  
Therapeutic Education ◽  
Maintenance Hemodialysis ◽  
Adherence To Treatment ◽  
Cross Sectional ◽  
Adherence Assessment ◽  
The Mean ◽  
Stage Renal Disease

Abstract Background and Aims Non-adherence to treatment is a major problem in patients with end stage renal disease and contributes to the significant increase in morbidity, mortality and health costs. Method The objective of this work was to assess adherence to treatment prescriptions for hemodialysis patients and to identify the predictive factors of poor compliance. This is a cross-sectional study of 59 patients on chronic hemodialysis. Adherence to treatment was evaluated by the adherence assessment test. Results The mean age of our patients was 51.8 years, with an M/F sex ratio of 1.26. The socio-economic level was considered low in 83% of cases. The mean duration of hemodialysis was 81.6 months [6 months-252 months]. Causal nephropathy was dominated by vascular nephropathy (13 cases). Forty-two patients had high blood pressure. A total of 23.9% of patients were good observers, 59.5% had minimal compliance problems, and 16.7% were poor observers. Statistical analysis has shown that poor adherence to treatment is associated with male gender, low socioeconomic and intellectual level, the presence of comorbidities, increased medication, number of medications taken per day, and less knowledge of the pathology and risks as side effects of drugs. Conclusion Treatment adherence is unsatisfactory in our population of patients on maintenance hemodialysis. Therapeutic education targeting the expected benefit of the treatments, their mode of action, their side effects as well as a simplification of the intake would improve long-term adherence in patients.

scholarly journals Adherence to therapy, lifestyle modification and medical support of cardiovascular patients

2020 ◽  
Vol 19 (6) ◽  
pp. 2665
Author(s):  
S. S. Bunova ◽  
N. I. Zhernakova ◽  
Yu. P. Skirdenko ◽  
N. A. Nikolaev
Keyword(s):  
Lifestyle Modification ◽  
Ethics Committees ◽  
Good Clinical Practice ◽  
Cross Sectional Study ◽  
Medical Support ◽  
Cross Sectional ◽  
Cardiovascular Patients ◽  
Adherence Assessment ◽  
Patients With Heart Failure ◽  
To Receive

Aim. To study the quantitative parameters of adherence to lifestyle modification, medical support,  and therapy in patients with cardiovascular diseases (CVD).Material and methods. This cross-sectional study included 683 respondents: 168 patients  with hypertension  (HTN); 196 patients  with stable angina; 141 patients with atrial fibrillation (AF); 178 patients with heart failure (HF). We used N. A. Nikolaev  questionnaire  for adherence assessment. For all adherence parameters, the level ≤75% was regarded as insufficient. The study was carried out in accordance with Good Clinical Practice and Declaration ofHelsinki. The study protocol was approved by the Ethics Committees of all participating clinical centers. All patients signed written informed consent.Results. Approximately 1/3 of respondents agreed  to receive therapy. The adherence level was >75%. Patients with angina and AF were more likely to receive therapy. It turned out that that approximately 2/3 of patients  were not ready for medical support.  Patients  with angina were less ready for medical support, while those with HTN and HF hadhigher values of adherence. Adherence to lifestyle modification was owest among analyzed parameters. Only 18,5% of hypertensive patients, 25,5% of patients with angina, 26,2% of AF patients and 23,1% of patients with HF were ready to change the lifestyle.Conclusion. The study revealed a significant number (~2/3) of CVD patients with insufficient adherence, which specifies the need  to assess the effectiveness  of therapy and course of the disease  in conditions of low adherence and to develop individualized therapeutic strategies.

scholarly journals Potential adherence to treatment in gastroenterological patients

2021 ◽  
pp. 134-141
Author(s):  
A. V. Gorbenko ◽  
Yu. P. Skirdenko ◽  
N. A. Nikolaev ◽  
M. A. Livzan ◽  
K. A. Andreev ◽  
...  
Keyword(s):  
Rating Scale ◽  
Pain Syndrome ◽  
Cross Sectional Study ◽  
Adherence To Treatment ◽  
Open Label ◽  
Cross Sectional ◽  
Individual Level ◽  
Low Level ◽  
Adherence Assessment ◽  
Medium Level

Objective. To assess the level of potential adherence to treatment in patients with gastrointestinal syndromes.Material and Methods. The open-label, cross- sectional study included 264 respondents who underwent preventive examinations. To identify gastroenterological syndromes we used Gastrointestinal Simptom Rating Scale (GSRS) questionnaire, which allows assessing the presence and the intensity of diarrheal, dyspeptic, constipation, refl ux syndrome and abdominal pain syndrome. The study group includes respondents who, according to the results of the GSRS questionnaire, have at least one syndrome (from 2 or more points) (N = 140). The comparison group included participants without gastrointestinal syndromes (N = 124). The level of adherence was assessed using the Quantitative Adherence Assessment Questionnaire (QAA-25). A score of less than 50% corresponds to a low level of adherence; a score between 50% and 75% corresponds to a medium level of adherence. Of 75% and above is considered to be a high and suffi cient level of adherence in the respondent.Results. Absolutely all respondents demonstrated an insuffi cient level of adherence to both drug therapy and medical support and lifestyle modifi cations. One in ten study participants had an medium level of adherence. The other 90% of patients from all groups had a low level of compliance (less than 50%) in all three areas of treatment adherence.Conclusions. Participants in our study were potentially unprepared for adherence to treatment that is consistent with optimal protocols. This demonstrates the need to work with adherence, both using ways to increase adherence and using patientcentered approaches that take into account the individual level of adherence.

Analisis Faktor Determinan yang berhubungan dengan Kepatuhan Rekomendasi Modifikasi Gaya Hidup Pasien Hipertensi

2020 ◽  
Vol 7 (2) ◽  
pp. 256-263
Author(s):  
Abdul Qodir
Keyword(s):  
Blood Pressure ◽  
Lifestyle Modification ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
Lifestyle Modifications ◽  
Chi Square ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Consecutive Sampling ◽  
Knowledge Practice

Penatalaksanaan farmakologis dan non farmakologis dipercaya dapat mengontrol tekanan darah dan mencegah komplikasi, tetapi banyak pasien hipertensi tekanan darahnya tidak terkontrol. Hal tersebut dikarenakan kepatuhan yang buruk dalam melaksanakan rekomendasi gaya hidup. Penelitian ini bertujuan untuk menganalisis determinan faktor yang berhungan dengan kepatuhan melaksanakan rekomendasi modifikasi gaya hidup. Penelitian ini menggunakan metode cross-sectional di pukesmas dinoyo Kota Malang tahun 2019. Teknik pengambilan sampel menggunakan Consecutive Sampling. Kuesioner yang digunakan meliputi : karakteristik demografi, pengetahuan dan rekomendasi mofifikasi gaya hidup pasien hipertensi. Hubungan antara rekomendasi modifikasi gaya hidup dengan variabel independen dianalisis menggunakan uji chi square dan analisis regresi logistik. 140 pasien hipertensi berpartisipasi dalam penelitian ini (60 laki-laki, 80 wanita). Prevalensi kepatuhan adalah 28,6 %. Tingkat pengetahuan berhubungan signifikan  dengan kepatuhan melaksanakan rekomendasi gaya hidup (p=0,00). Jenis kelamin, usia, dan tingkat pendidikan tidak mempunyai hubungan signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup (p= 0,06; p=0,21; p=0,87). Pengetahuan mempunyai hubungan yang signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup. Management of pharmacological and non-pharmacological is believed to control blood pressure and prevent complications,  but many hypertensive patients have uncontrolled blood pressure. This is due to poor adherence to recommended lifestyle modifications. This study was aimed to determine the factors associated with adherence to recommended lifestyle modifications of hypertensive patients. A cross-sectional study was conducted in Pukesmas Dinoyo Malang in 2019. Consecutive Sampling was used to select study subjects. The questionnaire included information about demographic characteristics, knowledge, practice of lifestyle-modification measures. Associations between adherence to lifestyle modification and independent variables were analyzed using chi square and multivariate logistic regression analysis. 140 hypertensive patients participated in the study (60 men, 80 women). The prevalence of adherence was 28.6%. The level of knowledge was significant associated with adherence to recommended lifestyle modifications (p = 0.00). Genders , age, and educational level were no significant associated with to recommended lifestyle modifications (p= 0.06; p=0.21; p=0.87). Knowledge was significant associated with adherence to recommended lifestyle modifications of hypertensive patients.

scholarly journals Examination of Construct Validity and Criterion-Related Validity of the German Motor Test in Egyptian Schoolchildren

2021 ◽  
Vol 18 (16) ◽  
pp. 8341
Author(s):  
Osama Abdelkarim ◽  
Julian Fritsch ◽  
Darko Jekauc ◽  
Klaus Bös
Keyword(s):  
Construct Validity ◽  
Physical Fitness ◽  
Large Scale ◽  
Body Height ◽  
Cross Sectional Study ◽  
Latent Factors ◽  
Cross Sectional ◽  
First Order ◽  
Motor Test ◽  
Health Related

Physical fitness is an indicator for children’s public health status. Therefore, the aim of this study was to examine the construct validity and the criterion-related validity of the German motor test (GMT) in Egyptian schoolchildren. A cross-sectional study was conducted with a total of 931 children aged 6 to 11 years (age: 9.1 ± 1.7 years) with 484 (52%) males and 447 (48%) females in grades one to five in Assiut city. The children’s physical fitness data were collected using GMT. GMT is designed to measure five health-related physical fitness components including speed, strength, coordination, endurance, and flexibility of children aged 6 to 18 years. The anthropometric data were collected based on three indicators: body height, body weight, and BMI. A confirmatory factor analysis was conducted with IBM SPSS AMOS 26.0 using full-information maximum likelihood. The results indicated an adequate fit (χ2 = 112.3, df = 20; p < 0.01; CFI = 0.956; RMSEA = 0.07). The χ2-statistic showed significant results, and the values for CFI and RMSEA showed a good fit. All loadings of the manifest variables on the first-order latent factors as well as loadings of the first-order latent factors on the second-order superordinate factor were significant. The results also showed strong construct validity in the components of conditioning abilities and moderate construct validity in the components of coordinative abilities. GMT proved to be a valid method and could be widely used on large-scale studies for health-related fitness monitoring in the Egyptian population.

Lifestyle modification adherence among patients attending diabetes clinics in selected hospitals in Remo zone Ogun State, Nigeria

2021 ◽  
Vol 4 (1) ◽  
pp. 23-32
Author(s):  
Adebayo Akadri ◽  
Omobolanle Akadri
Keyword(s):  
Logistic Regression ◽  
Lifestyle Modification ◽  
Exercise Adherence ◽  
Cross Sectional Study ◽  
Dietary Recommendations ◽  
Enabling Factors ◽  
Cross Sectional ◽  
Adherence To Diet ◽  
Ogun State ◽  
Diet And Exercise

Objective: Lifestyle modification is an essential component of self-management of diabetes mellitus. This study assessed adherence to diet and exercise recommendations and elucidated the factors that influence adherence in patients living with diabetes. Method: A cross-sectional study involving 300 patients attending diabetes clinics in some selected hospitals in Ogun State, Nigeria. Structured questionnaires were used to obtain information on the socio-demographic characteristics, and PRECEDE factors of lifestyle-modification adherence in the study participants. Pearson’s correlation and Chi-square test were used to assess the association between the variables, while binary logistic regression was used to determine the predictors of adherence to dietary recommendations. Results: The mean age of the study respondents was 62.7 years. The proportion of respondents who adhered to dietary and exercise recommendations were 87.8% and 45.6% respectively. There were no statistically significant linear relationships between scores for each PRECEDE factor and scores for adherence to diet and exercise. Respondents’ age, body mass index, and duration of illness had a statistically significant association with adherence to diet (P< 0.001, P=0.021, and P=0.041 respectively). On logistic regression analysis, participants 60 years and older had a higher likelihood of adhering to dietary modification than younger participants [AOR=2.6, P < 0.001]. Conclusion: The adherence of patients living with diabetes to dietary recommendations was satisfactory while adherence to exercise recommendations was very poor. There is a need for health care workers, especially at the primary and secondary levels to implement strategies that will enhance reinforcing and enabling factors for exercise adherence.

Compliance and Adherence to Treatment in Hypertensive Patients in different Tertiary Care Hospitals in Lahore

2021 ◽  
Vol 15 (8) ◽  
pp. 1858-1860
Author(s):  
Junaid Mushtaq ◽  
Israr-Ul- Haq ◽  
Waqas Mahmood ◽  
Mujtaba H. Siddiqui ◽  
Atiq Ahmad ◽  
...  
Keyword(s):  
Medical Center ◽  
Tertiary Care ◽  
Educational Status ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Adherence To Treatment ◽  
Cross Sectional ◽  
Hypertensive Patients ◽  
Hospital Doctors ◽  
Tertiary Care Hospitals

Aim: To determine the factors that affect compliance and adherence to medications of hypertensive patients visiting OPD clinics. Study design: Descriptive-cross sectional study. Place and duration of study: Department of Medicine, Unit 1, Lahore General Hospital, Doctors Hospital & Medical Center and Farooq Hospital Lahore from 1st January 2019 to 31st December 2019. Methodology: One hundred and sixty five patients with hypertension were handed over questionnaire socio-demographic, compliance and adherence were recorded. Results: Patients who maintained BP charting were only 13(7.9%) and those without BP charting were 152(92.1%). Patients taking regular medications were only 20(12.1%). Forgetfulness in taking medications was found in 47.3% of patients. 20.6% of patients were unable to purchase medicines because of financial reasons. Thirty two patients (19.4%) thought that they should not take medicines as they were not having any symptoms. Conclusion: Major causes of non-adherence were expense of medications, lack of symptoms, lack of money, forgetfulness, lack of awareness due to poor educational status and nature of job. Keywords: Compliance, Adherence, Medications, Hypertension, Forgetfulness

scholarly journals Serum paraoxonase-1 activity is associated with light to moderate alcohol consumption: the PREVEND cohort study

2018 ◽  
Vol 108 (6) ◽  
pp. 1283-1290 ◽  
Author(s):  
Eke G Gruppen ◽  
Stephan J L Bakker ◽  
Richard W James ◽  
Robin P F Dullaart
Keyword(s):  
Alcohol Consumption ◽  
Linear Regression Analysis ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
High Sensitivity ◽  
Population Based ◽  
Cross Sectional Study ◽  
Paraoxonase 1 ◽  
Phenyl Acetate ◽  
Cross Sectional

ABSTRACT Background Paraoxonase-1 (PON-1) is a high-density lipoprotein (HDL)-associated enzyme with antioxidative properties, which may protect against the development of cardiovascular disease. Alcohol consumption increases HDL cholesterol, but the extent to which alcohol consumption gives rise to higher serum PON-1 activity is uncertain. Objective In a population-based study, we determined the relation of serum PON-1 activity with alcohol consumption when taking account of HDL cholesterol and apolipoprotein A-I (apoA-I), its major apolipoprotein. Design A cross-sectional study was performed in 8224 participants of the Prevention of Renal and Vascular End-Stage Disease (PREVEND) cohort. Alcohol consumption was categorized as 1) no/rarely (25.3%); 2) 0.1–10 g/d (49.3%); 3) 10–30 g/d (20.1%); and 4) >30 g/d (5.2%) with 1 drink equivalent to 10 g alcohol. Serum PON-1 activity was measured as its arylesterase activity (phenyl acetate as substrate). Results Median serum PON-1 activity was 50.8, 53.1, 54.4, and 55.7 U/L in the 4 categories of alcohol consumption, respectively (P < 0.001). Its increase paralleled the increments in HDL cholesterol and apoA-I. Notably, there was no further increase in PON-1 activity, HDL cholesterol, and apoA-I when alcohol consumption was increased from 10–30 g/d to >30 g/d. Multivariable linear regression analysis demonstrated that PON-1 activity was related to alcohol consumption independently from clinical covariates, high sensitivity C-reactive protein, and lipid concentrations, including HDL cholesterol (P < 0.001 for each category of alcohol consumption with no alcohol consumption as the reference category). Notably, as inferred from standardized β-coefficients, there was no difference in PON-1 activity between 10–30 g alcohol/d and >30 g alcohol/d. Conclusions Alcohol consumption is associated with an increase in serum PON-1 activity, but its effect seems to reach a plateau with alcohol consumption of 10–30 g/d.

scholarly journals How to Evaluate Digital Leadership: A Cross-sectional Study

2021 ◽  
Author(s):  
Kevin Claassen ◽  
Dominique Rodil Dos Anjos ◽  
Jan Kettschau ◽  
Horst Christoph Broding
Keyword(s):  
Construct Validity ◽  
Online Survey ◽  
Leadership Skills ◽  
Principal Component ◽  
Cross Sectional Study ◽  
Working Environment ◽  
Cross Sectional ◽  
One Dimensional ◽  
Leadership Competence ◽  
Transformation Processes

Abstract Background: With the increasing digitalization of the working environment, the demands on managers are changing fundamentally to the point of an emerging field of research in digital leadership. Municipal administrations are particularly affected by the digital transformation processes. Therefore, a score to measure the construct of digital leadership competence in the context of virtual-based workstation was developed and tested.Methods: Based of an online survey with n = 546 employees at virtual-based workstations in municipal administrations in 2020, the instrument is tested regarding selectivity (coefficients), dimensionality (principal component analysis), homogeneity (inter-product-moment correlations), reliability (Cronbach's α) and construct validity (correlation with general leadership skills).Results: The instrument can be considered selective, one-dimensional, homogeneous, reliable and constructively valid in the sense of the formulated hypotheses. By integrating the employees‘ perspective, the instrument aims to be one of the first of its kind to initiate a scientific further discourse. Among other things, the categorization of the co-determination component as either traditional or digital leadership can be discussed.Conclusions: The developed instrument for measuring digital leadership performs well concerning the aspects of discriminatory power, one-dimensionality, homogeneity, reliability as well as construct validity. It aims to induce further research and a scientific discourse on the topic of health-oriented leadership within the world of work 4.0.

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