scholarly journals Evaluation of the Clinical Characteristics of Dry Eye Secondary to Different Types of Liver Diseases

2021 ◽  
Author(s):  
Shang Li ◽  
Ao Li ◽  
Fang Ruan ◽  
Wei Zhang ◽  
Jie Chen ◽  
...  
Keyword(s):  
Dry Eye ◽  
Clinical Characteristics ◽  
Statistical Difference ◽  
Surface Damage ◽  
High Rate ◽  
Primary Biliary Cholangitis ◽  
Drug Induced ◽  
Different Types ◽  
Meibomian Glands ◽  
The Difference

Abstract PurposeComparing the clinical characteristics of dry eye secondary to primary biliary cholangitis (PBC), drug-induced liver injury (DILI) and viral hepatitis B(HBV) to evaluate the ocular surface damage caused by different types of liver diseases.Methods32 patients with secondary dry eye, included 10 cases of PBC, 10 cases of DILI and 12 cases of HBV. All patients were evaluated by SPEED questionnaire, corneal fluorescein staining(CFS), non-invasive tear breakup time(NIBUT), Schirmer I test(SIt), tear meniscus height test(TMH), the area of meibomian glands dropout(MG dropout) , partial blinking rate(PBR) and lipid layer thickness(LLT).ResultsCompared with DILI and HBV groups, PBC group had a lower SPEED questionnaire score, but the difference was not statistically significant (F=0.83, P=0.45); the CFS score was higher (c2=7.16,P=0.03), the PBR was higher (F=14.34, P=0.00), the SIt was lower (F=4.30,P=0.02), and the differences were statistically significant. The TMH of PBC and DILI groups was significantly lower than HBV group, and the difference was statistically significant (F=4.15, P=0.02). Compared with PBC group, the LLT of DILI group decreased, the difference was statistically significant (P=0.03). The NIBUT of three groups was lower than normal, but there was no statistical difference between groups (Ff=1.35,Pf=0.27;Fa=2.03,Pa=0.14).The area of meibomian glands dropout of three groups had mild to moderate defects, but there was no significant statistical difference between groups (F=0.32, P=0.73).ConclusionsThe PBC group was more prone to aqueous-deficient dry eye. The DILI group was more prone to obstructive meibomian gland dysfunction (MGD).The HBV group was more prone to non-obstructive MGD. The symptoms of dry eye in the PBC group are mild to moderate discomfort, but the degree of corneal damage is higher, indicating that the corneal sensitivity is reduced, which may be related to the high rate of partial blinking.

scholarly journals Analysis of Clinical Characteristics of Immune-Related Dry Eye

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Hua Wang ◽  
Ping-Bao Wang ◽  
Ting Chen ◽  
Jing Zou ◽  
Ya-Jia Li ◽  
...  
Keyword(s):  
Dry Eye ◽  
Lupus Erythematosus ◽  
Ocular Surface ◽  
Clinical Characteristics ◽  
Nerve Fibers ◽  
Immune System Diseases ◽  
Corneal Nerve ◽  
The Difference ◽  
Surface Inflammation ◽  
Ocular Surface Inflammation

Aim. To discuss the clinical characteristics of immune-related dry eye. Methods. Simple dry eye (SDE) group: we selected 224 patients of simple dry eye with no systemic lesions. Immune-related dry eye (IRDE) group: we selected 207 patients of dry eye complicated with immune system diseases, including 70 cases of Sjögren’s syndrome (SS), 72 cases of systemic lupus erythematosus (SLE), and 65 cases of rheumatoid arthritis (RA). The classification of all patients was performed. The difference between the two groups was compared, including age, gender, ocular surface fluorescein staining and inflammatory reaction, tear breakup time (TBUT), Shirmer I test, confocal microscopy scan, and dry eye grading. Results. Compared with the SDE group, the patients of IRDE group were younger (P<0.05). The female patients were significantly more than the male ones (P<0.05). Corneal staining counts and ocular surface inflammation were significantly increased (P<0.05). TBUT and Shirmer I test shortened significantly (P<0.05). Corneal nerve fibers were less, and the number of local lymphocyte was significant increased. The number of dry eye patients in the moderate or above IRDE group was significantly increased (P<0.05). Conclusions. The dry eye symptom and sign and ocular surface inflammation of IRDE were significantly more severe than those of the SDE.

scholarly journals Pemanfaatan Limbah Hasil Perikanan: Lem Ikan Berbahan Baku Sisik Ikan yang Berbeda

2018 ◽  
Vol 1 (2) ◽  
pp. 60
Author(s):  
Dea Kurnia Sari
Keyword(s):  
Water Content ◽  
Wood Surface ◽  
Nile Tilapia ◽  
Surface Damage ◽  
National Standard ◽  
Fish Scales ◽  
Randomized Design ◽  
Different Types ◽  
The Difference ◽  
Tilapia Scale

Fishery processing industry such as fillet fish and boneless milkfish which are increasing rapidly raises new problem, that is industrial waste which one of them is fish scales. Fish scales in the know contain collagen which can be used as adhesive or glue and can be one of the innovations for waste processing of scales. The purpose of this study was to determine the effect of different fish scales on quality of fish glue from three different types of fish scales. The material used in this study is the scales of fish Seabass (Lates calcarifer), nile tilapia (Oreochromis niloticus), and milkfish (Chanos chanos Forks), acetic acid, NaOH, and aquadest. The research method used is experimental laboratories using Completely Randomized Design with treatment of three different types of fish scales with three repetitions each. The results obtained were analyzed using the analysis of variance, stickiness value, wood surface damage, viscosity, pH and water content of fish glue. To know the difference between treatments, the data were analyzed with real honest difference analysis. The results of this study showed that fish scales differed significantly (P <0.05) on all analysis, but not pH of fish glue. Based on the results of this study that meets the Indonesian National Standard no. 06-6049-1999 on Quality Requirements of Polyvinyl Acetate Emulsion For Wood Working Adhesives, Seabass fish scales is the best fish glue with quality: stickiness value 8.64 N/mm2, 40.47 % wood surface damage, viscosity 7.68 poise, pH 4.80, and water content of 59.92 %. Keywords: Fish glue; Milkfish Scale; Nile Tilapia Scale; Seabass Scale

scholarly journals Function and Morphology of the Meibomian Glands Using a LipiView Interferometer in Rotating Shift Medical Staff

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Jing Zhang ◽  
Zhengzheng Wu ◽  
Liangnan Sun ◽  
Xin-hua Liu
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Medical Staff ◽  
Night Shift ◽  
Control Group ◽  
Ocular Surface Disease Index ◽  
Significant Difference ◽  
Speed Score ◽  
Meibomian Glands ◽  
The Difference

Purpose. To investigate the function and morphology of meibomian glands (MG) in night shift medical staff (MS). Methods. Sixty-two eyes of 31 patients in the MS group and 59 eyes of 31 patients in the control group were consecutively enrolled. All participants completed Ocular Surface Disease Index (OSDI) and Standard Patient Dry Eye Evaluation (SPEED) questionnaires for dry eye severity, as well as Schirmer I and tear break-up time (TBUT) tests. LipiView® II Ocular Surface Interferometer was used for lipid layer thickness (LLT), MG dropout, and partial blink (PB) rate tests. MG expression was measured with an MG evaluator. Results. The OSDI score in the MS group was 22.39 ± 13.42, which was significantly higher than that in the control group (9.87 ± 6.64 Z = −3.997, P=0.001). The SPEED score in the MS group was 7.94 ± 3.81, which was significantly higher than in the control group (3.65 ± 2.11, Z = −4.766, P=0.001). There was no significant difference in Schirmer I test between the MS group and control group (Z = −1.346, P=0.178). TBUT in MS group was significantly shorter than that in the control group (Z = −5.201, P=0.001). The mean LLT of the MS group was 55.02 ± 21.17 nm significantly thinner than that of the control group 72.76 ± 21.62 nm (Z = −4.482, P=0.001). MG loss occurred in 45.16% of affected eyes in the MS group and 16.13% of affected eyes in the control group, and the difference was statistically significant (χ2 = 14.352, P=0.001). MG yielding liquid secretion and MG yielding secretion score were significantly lower in the MS group than in the control group (Z = −3.641, P=0.001; Z = −3.146, P=0.001, resp.). There was a negative correlation between mean LLT and SPEED score (Spearman r = −0.363, P=0.045). Conclusions. Night shift MS had a higher incidence of MGD compared to day workers.

scholarly journals Twelfth Grade Kuwaiti Students’ Identification of Domain and Range in Graphical Representation of Function and the Meaning they Ascribe to them

2019 ◽  
Vol 13 (3) ◽  
pp. 576
Author(s):  
Amal H. Alajmi
Keyword(s):  
Statistical Difference ◽  
Graphical Representation ◽  
Tukey Test ◽  
Significant Difference ◽  
Common Practices ◽  
Different Types ◽  
Twelfth Grade ◽  
Range Of Functions ◽  
The Difference ◽  
Low Performance

This research investigated twelfth grade students' performance in identification of domain and range of functions in a graphical representation. The study focused on four types of functions: polynomial, trigonometry, piecewise and discontinuous. The study also aimed to identify the meaning that students gave for the domain and range and how they identified them. To collect the data two instruments were used: a test and an interview. A sample of 216 students participated in the study. The results showed a low performance in identifying domain and range for functions in graphical representation. The T-test indicated a statistical difference in students’ performance in domain and range in favor of domain. The results indicated a statistically significant difference in students' performance among the different types of function. Tukey test showed that the difference was in favor of polynomial against the other types of function. Also there was a significant difference between trigonometry and piecewise items in favor of trigonometry. The interviews revealed that students’ meaning and common practices in identifying the domain and range reflected misunderstandings. Some of them highlighted that the domain is the x-axis and y-axis or the x-intercept and y- intercept. Others considered that the curve as the domain or the range.

scholarly journals Dry eye disease and its treatment in women over 45 years

2021 ◽  
Vol 21 (2) ◽  
pp. 103-107
Author(s):  
E.A. Drozdova ◽  
◽  
V.E. Balan ◽  
Keyword(s):  
Dry Eye ◽  
Tear Film ◽  
Meibomian Gland ◽  
Dry Eye Disease ◽  
High Rate ◽  
Eye Disease ◽  
Lipid Layer ◽  
Age Related ◽  
Meibomian Glands ◽  
Nano Emulsion

Epidemiological studies demonstrate an increase in age-related prevalence of dry eye disease (DED) and its higher occurrence in women. In addition to age-related alterations of structures producing tear film, the reduction of androgen levels and other regulating hormones is important for DED development. The role of estrogens and progesterone in the regulation of lacrimal and meibomian gland activity is still disputable. Additional factors of DED development in women are a high rate of comorbidities affecting gland functions, use of cosmetics and cosmetic procedures, contact lens wearing. The results are partial atrophy of meibomian glands, changes in the quality and amount of their secret, increased tear evaporation. Cationic nano-emulsion that addresses the deficiency and stabilize the lipid layer, increases water content, and reduces tear osmolarity is recommended for DED in women. Keywords: dry eye disease, tear film, meibomian glands, postmenopausal, lipid layer, tear osmolarity, artificial tears, cationic nano-emulsion. For citation: Drozdova E.A., Balan V.E. Dry eye disease and its treatment in women over 45 years. Russian Journal of Clinical Ophthalmology. 2021;21(2):103–107. DOI: 10.32364/2311-7729-2021-21-2-103-107.

Peritoneal Fluid and Plasma Fibrinolytic Activity in Women with Pelvic Inflammatory Disease

1992 ◽  
Vol 68 (02) ◽  
pp. 102-105 ◽  
Author(s):  
P J Dörr ◽  
E J P Brommer ◽  
G Dooijewaard ◽  
H M Vemer
Keyword(s):  
Pelvic Inflammatory Disease ◽  
Inflammatory Disease ◽  
Peritoneal Fluid ◽  
Fibrinolytic Activity ◽  
Degradation Products ◽  
Adhesion Formation ◽  
High Rate ◽  
Control Group ◽  
The Difference ◽  
Fibrinolytic Parameters

SummaryPrevious studies have shown that the fibrinolytic activity of peritoneum is depressed in local inflammation. We measured fibrinolytic parameters in peritoneal fluid and in plasma of 10 women with pelvic inflammatory disease (PID). Nine women, in whom laparoscopy for sterilisation was performed, served as a control group.In the peritoneal fluid of women with PID, PAI-Ag, t-PA-Ag and u-PA-Ag were many times higher than in the control group. In contrast to the antigens which may be present in inert complexes, the potentially active compounds, measured as t-PA activity and plasmin-activable scu-PA, were not significantly different in the two groups, and in none of the samples was the active enzyme tcu-PA detectable. Nevertheless, the mean peritoneal fluid TDP and FbDP concentrations were about twenty times higher in the PID group than in the control group. In plasma of PID patients, none of the parameters except u-PA-Ag differed from those in the control group. The difference between control and patient plasma u-PA-Ag was statistically significant, but too small to attach any relevance to the observation.Our data suggest that, in contrast to the classical concept of decreased fibrinolytic activity as a cause of adhesion formation, intraperitoneal fibrinolysis is enhanced in peritoneal inflammation through stimulation of the local production of t-PA and u-PA. Despite concomitant production of PAI, fibrinolysis occurs at a high rate, resulting in high levels of fibrin degradation products. Since this activated fibrinolysis does not meet the demand, therapeutic enhancement should be considered to prevent adhesions.

STUDY ON CLINICAL CHARACTERISTICS AND RESULT OF TREATMENT BENIGN VOCAL CORD TUMOR WITH RIGID LARYNGEAL ENDOSCOPIC SURGERY

2012 ◽  
pp. 58-65
Author(s):  
Duy Thai Truong ◽  
Van Dung Phan ◽  
Tu The Nguyen
Keyword(s):  
Vocal Cord ◽  
Endoscopic Surgery ◽  
Clinical Characteristics ◽  
University Hospital ◽  
High Rate ◽  
Treatment Rate ◽  
Reinke’S Edema ◽  
Vocal Nodules ◽  
A Prospective Study

Objective: Study on clinical characteristics and result of treatment benign vocal cord tumor with suspensive laryngeal endoscopic surgery. Materials and Methods: A prospective study was undertaken in 43 patients who had benign vocal cord tumor and performed a suspensive laryngeal endoscopic surgery at ENT Dept. of Hue University Hospital, from 3/2010 to 5/2011. Results: The most common was group was 31 - 45 (44.2%). There was no difference of gender. Moderate hoarness was 67.4%. Classification of benign laryngeal tumor: vocal nodules (13 cases), vocal cyst (18 cases), vocal polyp (10 cases) and Reinke’s edema (2 cases). The successful treatment rate of vocal benign tumor was 88.4%. Conclusions: Suspensive laryngeal endoscopic surgery was the best method to cure benign vocal cord tumor. The surgeon had a clear operative field, easy manoeuver, high rate of cure and less complication.

scholarly journals Anticoagulant treatment satisfaction with warfarin and direct oral anticoagulants for venous thromboembolism

2021 ◽  
Author(s):  
Margaret C. Fang ◽  
Alan S. Go ◽  
Priya A. Prasad ◽  
Jin-Wen Hsu ◽  
Dongjie Fan ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Treatment Satisfaction ◽  
Clinical Characteristics ◽  
Oral Anticoagulants ◽  
Direct Oral Anticoagulants ◽  
Treatment Options ◽  
Laboratory Monitoring ◽  
Routine Laboratory ◽  
Anticoagulant Treatment ◽  
The Difference

AbstractTreatment options for patients with venous thromboembolism (VTE) include warfarin and direct oral anticoagulants (DOACs). Although DOACs are easier to administer than warfarin and do not require routine laboratory monitoring, few studies have directly assessed whether patients are more satisfied with DOACs. We surveyed adults from two large integrated health systems taking DOACs or warfarin for incident VTE occurring between January 1, 2015 and June 30, 2018. Treatment satisfaction was assessed using the validated Anti-Clot Treatment Scale (ACTS), divided into the ACTS Burdens and ACTS Benefits scores; higher scores indicate greater satisfaction. Mean treatment satisfaction was compared using multivariable linear regression, adjusting for patient demographic and clinical characteristics. The effect size of the difference in means was calculated using a Cohen’s d (0.20 is considered a small effect and ≥ 0.80 is considered large). We surveyed 2217 patients, 969 taking DOACs and 1248 taking warfarin at the time of survey. Thirty-one point five percent of the cohort was aged ≥ 75 years and 43.1% were women. DOAC users were on average more satisfied with anticoagulant treatment, with higher adjusted mean ACTS Burdens (50.18 v. 48.01, p < 0.0001) and ACTS Benefits scores (10.21 v. 9.84, p = 0.046) for DOACs vs. warfarin, respectively. The magnitude of the difference was small (Cohen’s d of 0.29 for ACTS Burdens and 0.12 for ACTS Benefits). Patients taking DOACs for venous thromboembolism were on average more satisfied with anticoagulant treatment than were warfarin users, although the magnitude of the difference was small.

scholarly journals Investigation of Color Reproduction on Linen Fabrics when Printing with Mimaki TX400-1800D Inkjet with Pigment TP250 Dyes

Coatings ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 354
Author(s):  
Tim Tofan ◽  
Rimantas Stonkus ◽  
Raimondas Jasevičius
Keyword(s):  
Mechanical Properties ◽  
Color Reproduction ◽  
Related Effect ◽  
Color Characteristics ◽  
Fabric Density ◽  
Different Types ◽  
The Difference ◽  
Printing Parameters ◽  
Linen Fabric

The aim of this research is to investigate related effect of dyeability to linen textiles related to different printing parameters. The study investigated the change in color characteristics when printing on linen fabrics with an inkjet MIMAKI Tx400-1800D printer with pigmented TP 250 inks. The dependence of color reproduction on linen fabrics on the number of print head passes, number of ink layers to be coated, linen fabric density, and different types of linen fabric was investigated. All this affects the quality of print and its mechanical properties. The change in color characteristics on different types of linen fabrics was determined experimentally. We determine at which print settings the most accurate color reproduction can be achieved on different linen fabrics. The difference between the highest and the lowest possible number of head passages was investigated. The possibilities of reproducing different linen fabric colors were determined.

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