Distribution of ABO and Rh types in North of Asir region in Saudi Arabia

Abstract Background and Objectives.This study was conducted to form a better understanding of the distribution of ABO and Rh types among the population of the north of Asir region in Saudi Arabia and compare the findings to similar studies that were carried out in other parts of the kingdom and the Middle East. Understanding the frequency of different blood types in different populations is imperative. Blood types are essential not only for transfusion therapy but also for the prediction of the outcome of different diseases. The study aims to establish an understanding of the blood group frequency among the residents of the north of Asir region, Saudi Arabia. Additionally, this study was conducted to compare the blood group frequency in the region to that in different parts of the Arabian Peninsula.Subjects and Methods This study was done throughout 1year from January 1, 2020, to December 31, 2020, using samples from 4142 voluntary subjects at the blood bank of King Abdullah hospital, Bisha. Commercially provided ABO and Rh antibodies were used for the standard blood grouping procedure. Results:Our findings have shown that O is the most prominent ABO blood group while AB was the least frequent. The frequency of A blood type was the second high followed by B blood group while positive Rh factor was more common than the negative. A Comparison of our findings to other studies from Saudi Arabia and nations in the Middle East was also discussed.Conclusion:O+ >A+ >B+ > O->AB+> A->B- > AB- is the order of blood groups frequency in our study for males, while in females the order was almost the same except for the last three blood types was as following: >A->B->AB+. AB- on the other hand, was completely absent in female donors. There are some similarities and differences between our findings and that of other studies from the kingdom and other countries. Knowing and understanding the distribution of ABO and Rh types is essential for creating better policies for transfusion interventions and blood banks managements.

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ABO and RHD blood types distribution of the patients treated in the Federal Center of Cardiovascular Surgery of Krasnoyarsk

Clinical Medicine (Russian Journal) ◽

10.18821/0023-2149-2016-94-5-353-355 ◽

2016 ◽

Vol 94 (5) ◽

pp. 353-355

Author(s):

Aleksnder A. Makovskiy ◽

A. A. Popov ◽

S. D. Gysev ◽

L. I. Barhatova

Keyword(s):

Cardiovascular Surgery ◽

Type A ◽

Blood Type ◽

Transfusion Therapy ◽

Blood Types ◽

The People ◽

Hospital Patients ◽

Abo Blood Type ◽

The Mean ◽

Group B

The knowledge of blood types frequency in hospital patients helps to plan and perform transfusion therapy at blood donor centers. The distribution of patients’ blood by ABO groups and RhD allows to more efficiently organize and use donor blood banks. The risk of a disease is related to genome composition and is inherited with an ABO blood type. Every person should know his (her) ABO blood type and RhD to enable early identification of the first symptoms of an illness. Materials and methods. This work is based on the study of 4831 blood samples from patients treated at the Center of Cardiovascular Surgery in 2013 (2885 (59,7%) men of the mean age 55 years and 1946 (40,3 %) women of the mean age 57 years). Results. Type A blood occurred most frequently (1787 or 37,0% samples) followed by group O (1625 or 33,6% samples). Samples of group B made up 1025 of the total (21,2%), AB blood group was found in 394 samples (8,2%). Conclusion. The blood types distribution of the ABO system in the patients treated at the Center of Cardiovascular Surgery was characterized by the following pattern: A > O > B > AB. Group A was identified in 37,0% of the patients. Its frequency is similar to that in the population of the western part of Russia and Moscow but different from that in the people living in nearby regions. The frequency of RhD system antigens is comparable in all regions of Russia. CcDEe, ccDEe, CcDee, CCDee are considered to be the most widespread phenotypes. The residents of the Krasnoyarsk region and some nearby regions having blood type A apply to the Center of Cardiovascular Surgery with cardiovascular disorders more frequently than those with others ABO blood types.

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Effect of Intraoperative Blood Transfusion On Treg And Foxp3 In Patients With Digestive Tract Malignancies And Different Abo Blood Types

10.21203/rs.3.rs-34071/v1 ◽

2020 ◽

Author(s):

Yajun Liu ◽

Junzhi Sun ◽

Yun Xia ◽

Michael R. Lyaker ◽

Jianshe Yu

Keyword(s):

Blood Transfusion ◽

Digestive Tract ◽

Blood Group ◽

Radical Resection ◽

Foxp3 Expression ◽

Blood Type ◽

Foxp3 Mrna ◽

Blood Types ◽

Significant Difference ◽

Group A

Abstract Background Blood transfusion can cause immunosuppression and lead to worse outcomes in patients with digestive tract malignancies; however, the specific mechanism behind this is not completely understood. One theory is that increased numbers of regulatory CD3 + CD4 + CD25 + FOXP3 + T cells (Tregs) and forkhead box protein-3 mRNA (FOXP3) expression in the blood after transfusion contribute to these outcomes. The effect of blood transfusion on immune function in patients with different ABO blood types is variable. This study investigates the effect of intraoperative blood transfusion on the number of Tregs and the expression of FOXP3 in the blood of patients with different ABO blood types and digestive tract malignancies. Methods Patients with digestive tract malignancies who underwent radical resection and received intraoperative blood transfusion were divided into four groups according to their blood types:blood group A, B, O and AB (n=20 ). Blood was collected before surgery, immediately after transfusion, 1 day after transfusion, and 5 days after transfusion. The number of Tregs was measured by flow cytometry. The expression of FOXP3 was detected by real time reverse transcription polymerase chain reaction (RT-PCR). Results There was no significant difference in the number of Tregs or expression of FOXP3 mRNA among patients with different blood types before surgery. However, the number of Tregs and the expression of FOXP3 increased after blood transfusion in all blood type groups. This increase was especially evident and statistically significant on the first day after blood transfusion when compared with measures obtained before the surgery. Measures returned to the preoperative level five days after surgery. There were significant differences in the increase of Tregs and expression of FOXP3 among patients with different blood types. The greatest increase was seen in patients with blood group B and the least in blood group A. Conclusions Intraoperative blood transfusion can lead to an increase in blood Tregs and FOXP3 expression in patients with digestive tract malignancies. Increases were greatest on the first day after surgery and differed among patients with different blood types. Increases were greatest in blood type B and least in blood type A.

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Wild Felids Blood Group System

Animals ◽

10.3390/ani11123533 ◽

2021 ◽

Vol 11 (12) ◽

pp. 3533

Author(s):

Ana Silvestre-Ferreira ◽

Josep Pastor

Keyword(s):

Blood Group ◽

Current Knowledge ◽

Type A ◽

Blood Groups ◽

Blood Type ◽

Blood Group System ◽

Domestic Cats ◽

Blood Types ◽

Wild Felids ◽

Wild Cats

Wild felids and domestic cats share the AB blood group. However, there have been few studies regarding the characterization and prevalence of the different blood types in wild animals. The erythrocyte membrane glycolipids of the wild cats correspond to the major disialoganglioside patterns observed in domestic cats. Like in domestic cats, type A blood seems to be the most common, although wild felid species seem to exhibit one single blood type. Of the species studied, the wild domestic cats, and the Panthera and ocelot lineages, all had type A blood; the Puma lineage showed almost exclusively type B blood. The prevalence of wild felids blood types show that there seems to be variation between species, but not within species, and no evidence of geographical variation has yet been found, showing apparently no genetic variability. The presence of alloantibodies has also been demonstrated, so the risk of life-threatening transfusion reactions due to mismatched transfusions and neonatal isoerythrolysis is a possibility. Like in other species, the recognition of wild felids blood groups is clinically relevant, as it can also be important in establishing phylogenetic relationships within the Felidae family. We will review the current knowledge on this topic and give insights into the wild felids blood groups potential for zoo transfusion medicine and phylogenetic studies in order to help support reintroduction projects and to preserve genetic diversity.

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ABO Blood Groups and the Risk of Venous Thromboembolism (VTE) Among Saudi Patients at a Tertiary Care Hospital in Riyadh

Blood ◽

10.1182/blood-2019-128050 ◽

2019 ◽

Vol 134 (Supplement_1) ◽

pp. 4926-4926

Author(s):

Ghaydaa Juma Kullab ◽

Abdul Rehman Z. Zaidi ◽

Sultan Albaqmi ◽

Haya Alajlan ◽

Mohammed Abdullah Alsheef

Keyword(s):

Venous Thromboembolism ◽

Blood Group ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Blood Groups ◽

Blood Type ◽

Care Hospital ◽

Abo Blood Groups ◽

Blood Types ◽

Obesity Status

Background: ABO blood types are scientifically proved to be associated with the risk of venous thromboembolism (VTE), but data is lacking in the Saudi population. Aims: We aimed to investigate the association between ABO blood types and VTE, to explore potential interactions between ABO blood type with sex and obesity status. Methods: This was a retrospective study with a total of 998 patients, who were admitted with venous thromboembolism at our tertiary care hospital, between January 2010 and January 2018. Demographic and clinical data were collected. We used chi-square tests to assess the association between ABO blood group and the development of VTE. It was decided that the test will be considered significant if the p-value is <0.05. Results: Out of 998 VTE patients, 506 of patients were excluded, because their ABO blood group was not tested. Therefore, 492 patients were qualified as study subjects, of whom 66% of patients had DVT, 23% of patients had pulmonary embolism. Most of them had provoked VTE. Female patients constituted the majority of the study subjects (82.5%). Sample distribution appeared that O blood group was present in 34.1% of all VTE patients, while non-O-blood groups were present in 66% of them. Overall, there was a non-significant difference between VTE in patients with non-O blood type compared to O blood type (p=0.268). Conclusions: Non-O-blood groups (A, B, AB) are the most common blood types in Saudi patients with VTE. There is no statistically significant association between ABO blood groups, gender, and obesity status. Disclosures No relevant conflicts of interest to declare.

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ABO blood group and the risk of breast cancer: Multicenter, case-control, observational study.

Journal of Clinical Oncology ◽

10.1200/jco.2012.30.15_suppl.1572 ◽

2012 ◽

Vol 30 (15_suppl) ◽

pp. 1572-1572

Author(s):

Yuksel Urun ◽

Tulay Koru-Sengul ◽

Kadri Altundag ◽

Gungor Utkan ◽

Handan Onur ◽

...

Keyword(s):

Breast Cancer ◽

Prognostic Factors ◽

Blood Group ◽

Blood Groups ◽

Blood Type ◽

Abo Blood Group ◽

Abo Blood Groups ◽

Blood Types ◽

Abo Blood Type

1572 Background: The role of genetic factors in the development of cancer is widely accepted. ABO blood type is an inherited characteristic and previous studies have observed an association between ABO blood group and risk of certain malignancies, including pancreatic and gastric cancer. The data on the role of ABO blood group and Rh factor in breast cancer is inconclusive. Methods: All patients who had breast cancer (BC) and treated between 2000-2010 at the Departments of Medical Oncology of both Ankara and Hacettepe Universities (Ankara, Turkey) with defined ABO blood type and Rh factor were included in our retrospective reviews of tumor registry records. A group of volunteer healthy women donors of Turkish Red Crescent between 2004-2011 were identified as a control group, without any matching factors. The relationship of ABO blood types and Rh factor with various prognostic factors such as age at diagnosis, menopausal status, family history of breast cancer, and ER/PR/HER2 status were evaluated from 1740 BC patients. We compared the distributions of ABO blood types, Rh factors among 1740 patients and 204,553 healthy controls. Among BC patients, differences between each of aforementioned ABO blood groups and Rh factors with respect to various prognostic factors were explored, respectively. Results: Overall distributions of ABO blood groups as well as Rh factor were comparable between patients (44% A, 8% AB, 16% B, 32% O, 88% Rh+) and controls (41% A, 8% AB, 16% B, 35% O, 87% Rh+). However, there were statistically significant differences between patients and controls with respect to A vs. nonA (p=0.019) and marginal significance (p=0.051) for O vs. nonO. Among patients, there were statistically significant differences between A and nonA with respect to HER2 (p=0.0421), M stage (p=0.0447), T stage (p=0.0020). Only T stage (p=0.0337) were significantly different between O vs nonO. Grade (p=0.0227) and M stage (p=0.0107) were significantly different between Rh factors. Conclusions: In our study sample, ABO blood type was statistically significantly associated with breast cancer. Additional studies are necessary to determine the mechanisms by which ABO blood type may influence the risk of breast cancer.

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Frequencies of feline blood types in Hungary

Acta Veterinaria Hungarica ◽

10.1556/004.49.2001.4.1 ◽

2001 ◽

Vol 49 (4) ◽

pp. 369-375 ◽

Cited By ~ 13

Author(s):

Nóra Bagdi ◽

Melinda Magdus ◽

E. Leidinger ◽

Judith Leidinger ◽

K. Vörös

Keyword(s):

Blood Transfusion ◽

Blood Group ◽

Diagnostic Method ◽

Type A ◽

Blood Groups ◽

Blood Type ◽

Type B ◽

Blood Types ◽

Type Ab ◽

Transfusion Reactions

Feline blood group determination is done as a routine diagnostic method in numerous countries. Blood transfusion reactions and feline neonatal isoerythrolysis (FNI) can be avoided with the identification of different feline blood groups. The present study is the first investigation in Hungary during which 100 cats have been examined from all over the country. These cats were out of six breeds: European domestic shorthair, Persian mix, Persian, Abyssinian, Siamese and British shorthair. In the Hungarian feline population European domestic shorthair are most common but other breeds also occur. European domestic shorthair, Persian mix, Abyssinian, Siamese and British shorthair individuals all belonged to blood type A (100%). Blood type B was found very rarely and only in Persian cats. One-third of the Persian cats were categorised into blood type B, whilst type AB was not found during the study.

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Relation of ABO Blood Groups to the Plaque Characteristic of Coronary Atherosclerosis

BioMed Research International ◽

10.1155/2017/2674726 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 5

Author(s):

Xingtao Huang ◽

Yongpeng Zou ◽

Lulu Li ◽

Shuyuan Chen ◽

Jingbo Hou ◽

...

Keyword(s):

Blood Group ◽

Plaque Rupture ◽

Morphological Characteristics ◽

Coronary Plaque ◽

Blood Groups ◽

Blood Type ◽

Abo Blood Groups ◽

Blood Types ◽

Coronary Syndrome ◽

Fibrous Cap

The ABO blood types related to morphological characteristics of atherosclerosis plaque are not clear. We aimed to evaluate the relationship between ABO blood groups and the coronary plaque characteristic. We retrospectively identified the target lesions in 392 acute coronary syndrome patients who underwent optical coherence tomography examination before stenting. Subjects were divided into different groups according to different blood types. The fibrous cap thickness was significantly thicker in O type compared with non-O type (0.075±0.033 mm versus0.061±0.024,p<0.001). Meanwhile, the incidence of thin-cap fibroatheroma was also significantly higher in O type compared with non-O type (51.0% versus 71.5%,p<0.001). The O type showed a significantly larger minimum lumen area[1.26 (0.82, 2.13) versus 1.05 (0.67, 1.82),p=0.020]and minimum lumen diameter[1.03 (0.74, 1.31) versus 0.95 (0.66, 1.25),p=0.039]compared with non-O type. There were no differences found in incidence of lipid plaque, plaque rupture, and thrombus between different blood type groups even between O type and non-O type group (p>0.05). The plaques of O type blood group were exhibited more stably compared with non-O type blood group. Moreover, the non-O type blood group have more serious coronary artery stenosis than O type blood group.

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Distribution of ABO blood group in children with acute leukemias

Journal of Health Sciences ◽

10.17532/jhsci.2012.41 ◽

2012 ◽

Vol 2 (3) ◽

pp. 220-223

Author(s):

Meliha Sakić

Keyword(s):

Acute Leukemia ◽

Blood Group ◽

Blood Type ◽

Abo Blood Group ◽

Type B ◽

Acute Leukemias ◽

Blood Types ◽

Number Of Children ◽

Pediatric Clinic ◽

Type Ab

Introduction: This study is the fi rst study about the distribution ABO blood types at children with acute leukemia in Federation of Bosnia and Herzegovina. The aim of the study is to point out distribution of blood type groups at children with acute leukemia (AL)Methods: The number of children in this study was the following: 145 children with acute leukemia and 27 of children with acute myeloblastic leukemia (AML). All of the children were treated at Hemato- Oncology Unitof Pediatric Clinic in Sarajevo, in the period January 2000 until December 2010. Age of children was between 1 month and 15 years.Results: The results showed that different blood types were registered in 93. 1% of children who got ill and treated from acute leukemia for the mentioned period. At 6. 9 % of children, none of the blood types wereregistered. It was noticed that 40.9 % children who have registered blood type O, 37% blood type A,16% blood type B and 6.5% blood type AB had AL, too. It has been observed that children with following bloodtypes had AML: O, 47.8%, A, 47.7% and AB, 30.4%.Conclusion: Signifi cance ABO types distribution was confi rmed for children with ALL, p<0, 05. The analysis of the distribution of ABO types based on gender showed that signifi cance was confi rmed at females with both ALL and AML (p<0.05).

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Mission to the Near East

International Review of the Red Cross ◽

10.1017/s0020860400013590 ◽

1964 ◽

Vol 4 (36) ◽

pp. 134-134

Keyword(s):

Saudi Arabia ◽

Middle East ◽

Near East ◽

Vice President ◽

International Committee ◽

Red Cross ◽

Field Hospital ◽

The North

The Vice-President of the International Committee of the Red Cross, Mr. Samuel Gonard, returned on February 10 to Geneva, after a four week tour in the Middle East. He visited the ICRC delegations in Saudi Arabia and in the Yemen and in particular inspected the field hospital at Uqhd in the North of the Yemen, where wounded and sick victims of the war from both sides are cared for.

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Using red blood cell genomics in transfusion medicine

Hematology ◽

10.1182/asheducation-2015.1.168 ◽

2015 ◽

Vol 2015 (1) ◽

pp. 168-176 ◽

Cited By ~ 4

Author(s):

Jill M. Johnsen

Keyword(s):

Next Generation Sequencing ◽

Blood Group ◽

Clinical Laboratory ◽

Clinical Problem ◽

Blood Type ◽

Blood Group Antigens ◽

Next Generation ◽

Blood Typing ◽

Blood Types ◽

Generation Sequencing

Abstract Blood types (blood group antigens) are heritable polymorphic antigenic molecules on the surface of blood cells. These were amongst the first human Mendelian traits identified, and the genetic basis of nearly all of the hundreds of blood types is known. Clinical laboratory methods have proven useful to identify selected blood group gene variants, and use of genetic blood type information is becoming widespread. However, the breadth and complexity of clinically relevant blood group genetic variation poses challenges. With recent advances in next-generation sequencing technologies, a more comprehensive DNA sequence-based genetic blood typing approach is now feasible. This chapter introduces the practitioner to high-resolution genetic blood typing beginning with an overview of the genetics of blood group antigens, the clinical problem of allosensitization, current blood type testing methods, and then discussion of next-generation sequencing and its application to the problem of genetic blood typing.

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