scholarly journals Machine learning algorithms to predict 30-day readmission in patients with stroke: a prospective cohort study

2020 ◽  
Author(s):  
Yu-Ching Chen ◽  
Jo-Hsuan Chung ◽  
Yu-Jo Yeh ◽  
Hsiu-Fen Lin ◽  
Ching-Huang Lin ◽  
...  
Keyword(s):  
Machine Learning ◽  
Cox Regression ◽  
Learning Algorithms ◽  
External Validation ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Significant Variable ◽  
Ann Model ◽  
Stroke Patients ◽  
Forecasting Models

Abstract Background No studies have discussed machine learning algorithms to predict the risk of 30-day readmission in patients with stroke. The objective of the present study was to compare the accuracy of the artificial neural network (ANN), K nearest neighbor (KNN), support vector machine (SVM), naive Bayes classifier (NBC), and Cox regression (COX) models and to explore the significant factors in predicting 30-day readmission after stroke. Methods This study prospectively compared the accuracy of the models using clinical data for 1,476 patients with stroke treated in six hospitals between March, 2014 and September, 2019. A training dataset (n=1,033) was used for model development, a testing dataset (n=443) was used for internal validation, and a validating dataset (n=167) was used for external validation. A global sensitivity analysis was performed to compare the significance of the selected input variables. Results Of all forecasting models, the ANN model had the highest accuracy in predicting 30-day readmission after stroke and had the highest overall performance indices. According to the ANN model, 30-day readmission was significantly associated with post-acute care (PAC) program, patient attributes, clinical attributes, and functional status scores before re-habilitation (all P <0.05). Additionally, PAC program was the most significant variable affecting 30-day readmission, followed by nasogastric tube insertion, and stroke type ( P <0.05). Conclusions Comparisons of the five forecasting models indicated that the ANN model had the highest accuracy in predicting 30-day readmission in stroke patients. Before stroke patients are discharged from hospitalization, they should be counseled regarding their potential for recovery and other possible outcomes. These important predictors can also be used to educate candidates for stroke patients who underwent PAC rehabilitation with respect to the course of recovery and health outcomes.

scholarly journals Machine learning algorithms to identify cluster randomized trials from MEDLINE and EMBASE

2021 ◽  
Author(s):  
Ahmed A Al-Jaishi ◽  
Monica Taljaard ◽  
Melissa D Al-Jaishi ◽  
Sheikh S Abdullah ◽  
Lehana Thabane ◽  
...  
Keyword(s):  
Machine Learning ◽  
Randomized Trials ◽  
Learning Algorithms ◽  
External Validation ◽  
Machine Learning Algorithms ◽  
Bibliographic Databases ◽  
Support Vector ◽  
Cluster Randomized Trials ◽  
Ensemble Algorithm ◽  
Cluster Randomized

Abstract Background: Cluster randomized trials (CRTs) are becoming an increasingly important design. However, authors do not always adhere to requirements to explicitly identify the design as cluster randomized in titles and abstracts, making retrieval from bibliographic databases difficult. Machine learning algorithms may improve their identification and retrieval. Therefore, we aimed to develop machine learning algorithms that accurately determine whether a bibliographic citation is a CRT report. Methods: We trained, internally validated, and externally validated two convolutional neural networks and one support vector machines (SVM) algorithms to predict whether a citation is a CRT report or not. We exclusively used the information in an article citation, including the title, abstract, keywords, and subject headings. The algorithms' output was a probability from 0 to 1. We assessed algorithm performance using the area under the receiver operating characteristic (AUC) curves. Each algorithm's performance was evaluated individually and together as an ensemble. We randomly selected 5000 from 87,633 citations to train and internally validate our algorithms. Of the 5000 selected citations, 589 (12%) were confirmed CRT reports. We then externally validated our algorithms on an independent set of 1916 randomized trial citations, with 665 (35%) confirmed CRT reports. Results: In internal validation, the ensemble algorithm discriminated best for identifying CRT reports with an AUC of 98.6% (95% confidence interval: 97.8%, 99.4%), sensitivity of 97.7% (94.3%, 100%), and specificity of 85.0% (81.8%, 88.1%). In external validation, the ensemble algorithm had an AUC of 97.8 % (97.0%, 98.5%), sensitivity of 97.6% (96.4%, 98.6%), and specificity of 78.2% (75.9%, 80.4%)). All three individual algorithms performed well, but less so than the ensemble. Conclusions: We successfully developed high-performance algorithms that identified whether a citation was a CRT report with high sensitivity and moderately high specificity. We provide open-source software to facilitate the use of our algorithms in practice.

scholarly journals Prediction of Cardiac Mechanical Performance From Electrical Features During Ventricular Tachyarrhythmia Simulation Using Machine Learning Algorithms

2020 ◽  
Vol 11 ◽  
Author(s):  
Da Un Jeong ◽  
Ki Moo Lim
Keyword(s):  
Machine Learning ◽  
Stroke Volume ◽  
Mechanical Performance ◽  
Learning Algorithms ◽  
Ventricular Tachyarrhythmia ◽  
Predictive Performance ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Ann Model ◽  
Electrical Instability

In ventricular tachyarrhythmia, electrical instability features including action potential duration, dominant frequency, phase singularity, and filaments are associated with mechanical contractility. However, there are insufficient studies on estimated mechanical contractility based on electrical features during ventricular tachyarrhythmia using a stochastic model. In this study, we predicted cardiac mechanical performance from features of electrical instability during ventricular tachyarrhythmia simulation using machine learning algorithms, including support vector regression (SVR) and artificial neural network (ANN) models. We performed an electromechanical tachyarrhythmia simulation and extracted 12 electrical instability features and two mechanical properties, including stroke volume and the amplitude of myocardial tension (ampTens). We compared predictive performance according to kernel types of the SVR model and the number of hidden layers of the ANN model. In the SVR model, the prediction accuracies of stroke volume and ampTens were the highest when using the polynomial kernel and linear kernel, respectively. The predictive performance of the ANN model was better than that of the SVR model. The prediction accuracies were the highest when the ANN model consisted of three hidden layers. Accordingly, we propose the ANN model with three hidden layers as an optimal model for predicting cardiac mechanical contractility in ventricular tachyarrhythmia. The results of this study are expected to be used to indirectly estimate the hemodynamic response from the electrical cardiac map measured by the optical mapping system during cardiac surgery, as well as cardiac contractility under normal sinus rhythm conditions.

scholarly journals Systematic literature review of machine learning methods used in the analysis of real-world data for patient-provider decision making

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Alan Brnabic ◽  
Lisa M. Hess
Keyword(s):  
Machine Learning ◽  
Decision Making ◽  
Literature Review ◽  
Systematic Literature Review ◽  
Real World ◽  
Learning Algorithms ◽  
External Validation ◽  
Machine Learning Algorithms ◽  
Learning Methods ◽  
Machine Learning Methods

Abstract Background Machine learning is a broad term encompassing a number of methods that allow the investigator to learn from the data. These methods may permit large real-world databases to be more rapidly translated to applications to inform patient-provider decision making. Methods This systematic literature review was conducted to identify published observational research of employed machine learning to inform decision making at the patient-provider level. The search strategy was implemented and studies meeting eligibility criteria were evaluated by two independent reviewers. Relevant data related to study design, statistical methods and strengths and limitations were identified; study quality was assessed using a modified version of the Luo checklist. Results A total of 34 publications from January 2014 to September 2020 were identified and evaluated for this review. There were diverse methods, statistical packages and approaches used across identified studies. The most common methods included decision tree and random forest approaches. Most studies applied internal validation but only two conducted external validation. Most studies utilized one algorithm, and only eight studies applied multiple machine learning algorithms to the data. Seven items on the Luo checklist failed to be met by more than 50% of published studies. Conclusions A wide variety of approaches, algorithms, statistical software, and validation strategies were employed in the application of machine learning methods to inform patient-provider decision making. There is a need to ensure that multiple machine learning approaches are used, the model selection strategy is clearly defined, and both internal and external validation are necessary to be sure that decisions for patient care are being made with the highest quality evidence. Future work should routinely employ ensemble methods incorporating multiple machine learning algorithms.

scholarly journals Hierarchical Tactile Sensation Integration from Prosthetic Fingertips Enables Multi-Texture Surface Recognition

Sensors ◽  
2021 ◽  
Vol 21 (13) ◽  
pp. 4324
Author(s):  
Moaed A. Abd ◽  
Rudy Paul ◽  
Aparna Aravelli ◽  
Ou Bai ◽  
Leonel Lagos ◽  
...  
Keyword(s):  
Machine Learning ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Sliding Contact ◽  
Tactile Sensation ◽  
Support Vector ◽  
Textured Surfaces ◽  
K Nearest Neighbor ◽  
Tactile Sensors ◽  
Time Frequency

Multifunctional flexible tactile sensors could be useful to improve the control of prosthetic hands. To that end, highly stretchable liquid metal tactile sensors (LMS) were designed, manufactured via photolithography, and incorporated into the fingertips of a prosthetic hand. Three novel contributions were made with the LMS. First, individual fingertips were used to distinguish between different speeds of sliding contact with different surfaces. Second, differences in surface textures were reliably detected during sliding contact. Third, the capacity for hierarchical tactile sensor integration was demonstrated by using four LMS signals simultaneously to distinguish between ten complex multi-textured surfaces. Four different machine learning algorithms were compared for their successful classification capabilities: K-nearest neighbor (KNN), support vector machine (SVM), random forest (RF), and neural network (NN). The time-frequency features of the LMSs were extracted to train and test the machine learning algorithms. The NN generally performed the best at the speed and texture detection with a single finger and had a 99.2 ± 0.8% accuracy to distinguish between ten different multi-textured surfaces using four LMSs from four fingers simultaneously. The capability for hierarchical multi-finger tactile sensation integration could be useful to provide a higher level of intelligence for artificial hands.

Machine Learning Models for Finger Bend Evaluation using Implemented Low cost Flex Sensor

2021 ◽  
Vol 9 (VI) ◽  
pp. 3605-3611
Author(s):  
Pratyush Kaware
Keyword(s):  
Machine Learning ◽  
Support Vector Machine ◽  
Low Cost ◽  
Learning Algorithms ◽  
Cost Effective ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Learning Models ◽  
Machine Learning Models

In this paper a cost-effective sensor has been implemented to read finger bend signals, by attaching the sensor to a finger, so as to classify them based on the degree of bent as well as the joint about which the finger was being bent. This was done by testing with various machine learning algorithms to get the most accurate and consistent classifier. Finally, we found that Support Vector Machine was the best algorithm suited to classify our data, using we were able predict live state of a finger, i.e., the degree of bent and the joints involved. The live voltage values from the sensor were transmitted using a NodeMCU micro-controller which were converted to digital and uploaded on a database for analysis.

scholarly journals Heart disease prediction using machine learning techniques : a survey

2018 ◽  
Vol 7 (2.8) ◽  
pp. 684 ◽  
Author(s):  
V V. Ramalingam ◽  
Ayantan Dandapath ◽  
M Karthik Raja
Keyword(s):  
Machine Learning ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Complex Data ◽  
Learning Techniques ◽  
Vector Machines ◽  
Supervised Learning Algorithms ◽  
Life Threatening

Heart related diseases or Cardiovascular Diseases (CVDs) are the main reason for a huge number of death in the world over the last few decades and has emerged as the most life-threatening disease, not only in India but in the whole world. So, there is a need of reliable, accurate and feasible system to diagnose such diseases in time for proper treatment. Machine Learning algorithms and techniques have been applied to various medical datasets to automate the analysis of large and complex data. Many researchers, in recent times, have been using several machine learning techniques to help the health care industry and the professionals in the diagnosis of heart related diseases. This paper presents a survey of various models based on such algorithms and techniques andanalyze their performance. Models based on supervised learning algorithms such as Support Vector Machines (SVM), K-Nearest Neighbour (KNN), NaïveBayes, Decision Trees (DT), Random Forest (RF) and ensemble models are found very popular among the researchers.

scholarly journals Feature Selection and Comparison of Machine Learning Algorithms in Classification of Grazing and Rumination Behaviour in Sheep

Sensors ◽  
2018 ◽  
Vol 18 (10) ◽  
pp. 3532 ◽  
Author(s):  
Nicola Mansbridge ◽  
Jurgen Mitsch ◽  
Nicola Bollard ◽  
Keith Ellis ◽  
Giuliana Miguel-Pacheco ◽  
...  
Keyword(s):  
Machine Learning ◽  
Random Forest ◽  
Time Budget ◽  
Learning Algorithms ◽  
Eating Behaviour ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Optimum Number ◽  
Eating Behaviours ◽  
Adaptive Boosting

Grazing and ruminating are the most important behaviours for ruminants, as they spend most of their daily time budget performing these. Continuous surveillance of eating behaviour is an important means for monitoring ruminant health, productivity and welfare. However, surveillance performed by human operators is prone to human variance, time-consuming and costly, especially on animals kept at pasture or free-ranging. The use of sensors to automatically acquire data, and software to classify and identify behaviours, offers significant potential in addressing such issues. In this work, data collected from sheep by means of an accelerometer/gyroscope sensor attached to the ear and collar, sampled at 16 Hz, were used to develop classifiers for grazing and ruminating behaviour using various machine learning algorithms: random forest (RF), support vector machine (SVM), k nearest neighbour (kNN) and adaptive boosting (Adaboost). Multiple features extracted from the signals were ranked on their importance for classification. Several performance indicators were considered when comparing classifiers as a function of algorithm used, sensor localisation and number of used features. Random forest yielded the highest overall accuracies: 92% for collar and 91% for ear. Gyroscope-based features were shown to have the greatest relative importance for eating behaviours. The optimum number of feature characteristics to be incorporated into the model was 39, from both ear and collar data. The findings suggest that one can successfully classify eating behaviours in sheep with very high accuracy; this could be used to develop a device for automatic monitoring of feed intake in the sheep sector to monitor health and welfare.

scholarly journals A Comparative Analysis of Machine Learning Algorithms Modeled from Machine Vision-Based Lettuce Growth Stage Classification in Smart Aquaponics

2020 ◽  
Vol 11 (9) ◽  
pp. 442-449 ◽  
Author(s):  
Sandy C. Lauguico ◽  
◽  
Ronnie S. Concepcion II ◽  
Jonnel D. Alejandrino ◽  
Rogelio Ruzcko Tobias ◽  
...  
Keyword(s):  
Machine Learning ◽  
Comparative Analysis ◽  
Machine Vision ◽  
Nearest Neighbor ◽  
Learning Algorithms ◽  
Machine Learning Algorithms ◽  
Support Vector ◽  
Urban Farming ◽  
K Nearest Neighbor ◽  
Lettuce Growth

The arising problem on food scarcity drives the innovation of urban farming. One of the methods in urban farming is the smart aquaponics. However, for a smart aquaponics to yield crops successfully, it needs intensive monitoring, control, and automation. An efficient way of implementing this is the utilization of vision systems and machine learning algorithms to optimize the capabilities of the farming technique. To realize this, a comparative analysis of three machine learning estimators: Logistic Regression (LR), K-Nearest Neighbor (KNN), and Linear Support Vector Machine (L-SVM) was conducted. This was done by modeling each algorithm from the machine vision-feature extracted images of lettuce which were raised in a smart aquaponics setup. Each of the model was optimized to increase cross and hold-out validations. The results showed that KNN having the tuned hyperparameters of n_neighbors=24, weights='distance', algorithm='auto', leaf_size = 10 was the most effective model for the given dataset, yielding a cross-validation mean accuracy of 87.06% and a classification accuracy of 91.67%.

scholarly journals Automatic Grading of Stroke Symptoms for Rapid Assessment Using Optimized Machine Learning and 4-Limb Kinematics: Clinical Validation Study (Preprint)

2020 ◽  
Author(s):  
Eunjeong Park ◽  
Kijeong Lee ◽  
Taehwa Han ◽  
Hyo Suk Nam
Keyword(s):  
Machine Learning ◽  
Medical Staff ◽  
Machine Learning Algorithms ◽  
Training Data ◽  
Support Vector ◽  
Grading System ◽  
Operating Characteristics ◽  
Stroke Patients ◽  
Motor Weakness ◽  
Automatic Grading

BACKGROUND Subtle abnormal motor signs are indications of serious neurological diseases. Although neurological deficits require fast initiation of treatment in a restricted time, it is difficult for nonspecialists to detect and objectively assess the symptoms. In the clinical environment, diagnoses and decisions are based on clinical grading methods, including the National Institutes of Health Stroke Scale (NIHSS) score or the Medical Research Council (MRC) score, which have been used to measure motor weakness. Objective grading in various environments is necessitated for consistent agreement among patients, caregivers, paramedics, and medical staff to facilitate rapid diagnoses and dispatches to appropriate medical centers. OBJECTIVE In this study, we aimed to develop an autonomous grading system for stroke patients. We investigated the feasibility of our new system to assess motor weakness and grade NIHSS and MRC scores of 4 limbs, similar to the clinical examinations performed by medical staff. METHODS We implemented an automatic grading system composed of a measuring unit with wearable sensors and a grading unit with optimized machine learning. Inertial sensors were attached to measure subtle weaknesses caused by paralysis of upper and lower limbs. We collected 60 instances of data with kinematic features of motor disorders from neurological examination and demographic information of stroke patients with NIHSS 0 or 1 and MRC 7, 8, or 9 grades in a stroke unit. Training data with 240 instances were generated using a synthetic minority oversampling technique to complement the imbalanced number of data between classes and low number of training data. We trained 2 representative machine learning algorithms, an ensemble and a support vector machine (SVM), to implement auto-NIHSS and auto-MRC grading. The optimized algorithms performed a 5-fold cross-validation and were searched by Bayes optimization in 30 trials. The trained model was tested with the 60 original hold-out instances for performance evaluation in accuracy, sensitivity, specificity, and area under the receiver operating characteristics curve (AUC). RESULTS The proposed system can grade NIHSS scores with an accuracy of 83.3% and an AUC of 0.912 using an optimized ensemble algorithm, and it can grade with an accuracy of 80.0% and an AUC of 0.860 using an optimized SVM algorithm. The auto-MRC grading achieved an accuracy of 76.7% and a mean AUC of 0.870 in SVM classification and an accuracy of 78.3% and a mean AUC of 0.877 in ensemble classification. CONCLUSIONS The automatic grading system quantifies proximal weakness in real time and assesses symptoms through automatic grading. The pilot outcomes demonstrated the feasibility of remote monitoring of motor weakness caused by stroke. The system can facilitate consistent grading with instant assessment and expedite dispatches to appropriate hospitals and treatment initiation by sharing auto-MRC and auto-NIHSS scores between prehospital and hospital responses as an objective observation.

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