Immune-Related lncRNAs to Construct Novel Signature for Predicting Prognosis in Gastric Cancer
Abstract Background: Long non coding RNAs (lncRNAs) have many functions, including immune response. The signal irlncRNAs with no requirement of specific expression level seems to be valuable in predicting the prognosis of patients with gastric cancer (GC). Results: Our results suggested that immune related lncRNA signaling is of great value in predicting prognosis, and it may be possible to measure the response to immunotherapy. This feature may guide the choice of immunotherapy for GC. Conclusion: Immune-related lncRNA signals show independent prognostic significance in GC. These results of this research could predict the prognosis of GC patients without detecting specific expression level of lncRNA, providing a possible method for predicting the survival of GC patients, and providing a potential lncRNA target for immunotherapy.