InterCellar enables interactive analysis and exploration of cell−cell communication in single-cell transcriptomic data

Deciphering cell−cell communication is a key step in understanding the physiology and pathology of multicellular systems. Recent advances in single-cell transcriptomics have contributed to unraveling the cellular composition of tissues and enabled the development of computational algorithms to predict cellular communication mediated by ligand−receptor interactions. Despite the existence of various tools capable of inferring cell−cell interactions from single-cell RNA sequencing data, the analysis and interpretation of the biological signals often require deep computational expertize. Here we present InterCellar, an interactive platform empowering lab-scientists to analyze and explore predicted cell−cell communication without requiring programming skills. InterCellar guides the biological interpretation through customized analysis steps, multiple visualization options, and the possibility to link biological pathways to ligand−receptor interactions. Alongside convenient data exploration features, InterCellar implements data-driven analyses including the possibility to compare cell−cell communication from multiple conditions. By analyzing COVID-19 and melanoma cell−cell interactions, we show that InterCellar resolves data-driven patterns of communication and highlights molecular signals through the integration of biological functions and pathways. We believe our user-friendly, interactive platform will help streamline the analysis of cell−cell communication and facilitate hypothesis generation in diverse biological systems.

Analysis of Language Errors in the “Larise” Magazine Article at SMP Negeri 8 Surakarta

This study aims to analyze language errors and their interpretations at the level of syntax, morphology, and Indonesian Spelling System as well as to increase knowledge and insight about how to write properly and correctly according to the language rules that have been regulated in the KBBI and PUEBI. This research uses descriptive qualitative research method. The data in this study are in the form of words (not numbers) sourced from Larise magazine in an article entitled "Philosophy of Kidungan Jawa "Ana Kidung Rumeksa ing Wengi" published on Sunday, October 11, 2020. The data collection technique in this study is a note-taking technique, namely: by reading Larise magazine as a data source. The analysis used in this study is an interactive analysis which includes the steps of a) data collection, b) error identification, c) error explanation, d) error classification, and e) error evaluation. In this study, an analysis of errors in writing rules was carried out at the level of syntax, morphology, and accuracy in the use of Indonesian Spelling (EBI). Errors at the syntactic level are in the form of errors in the use of effective sentences, errors at the morphological level are affixation errors, and errors related to Indonesian spelling include errors in using punctuation marks, using capital letters, using standard words, using prepositions, and using particles

Pola Pembinaan Prestasi Olahraga Beladiri Wushu Koni Kabupaten Semarang Di Masa Pandemi Covid 19

The purpose of this study is to describe the pattern of fostering the sports achievement of wushu martial arts in the KONI Kabupaten Semarang during the Covid 19 pandemic. This study uses descriptive qualitative methods. Sources of data in this study consisted of athletes, coaches, and administrators of the KONI Kabupaten Semarang. The data collection technique is an interview technique. The data analysis technique used an interactive analysis model. The results showed that the pattern of fostering the sports achievement of the KONI Kabupaten Semarang uses a talent scouting system, which means the process of scouting the talents of athletes from the recruitment stage to the final stage of coaching. The spirit of training and the athletes' efforts to achieve optimal performance are supported by the quality of the coaches which are already good, because all coaches have coach certification, and the training programs provided are in the good category. The management organization in good criteria is seen from the attention of the administrators to the athletes, and the management of Wushu martial arts. The facilities and infrastructure owned are included in the criteria both in terms of the completeness and quality of the existing facilities and infrastructure. Funding for the implementation of Wushu martial arts performance coaching is included in the criteria both seen from the source of funding and how to allocate funds for the coaching process. The conclusion obtained is that the pattern of fostering wushu martial sports achievements at the KONI Kabupaten Semarang is running well, has been programmed, tiered, and sustainable.

Pembelajaran Masa Pandemi pada Anak Masyarakat Petani Pedalaman di Aceh Selatan

This study aims to determine the community's response to the pandemic and learning practices during the pandemic for the children of rural farmers in South Aceh. This study uses a qualitative approach with a descriptive model. Data obtained from observations, interviews, and relevant literature studies, then analyzed the data, researchers will use interactive analysis techniques. The results of this study indicate that 1) The public's perception of risk for a pandemic is low, but the community continues to respond well to this pandemic, namely complying with health protocols by using masks when going out to public places. 2) Learning activities for children from rural farming communities in Kluet Tengah continued as usual. Like other schools that adhere to the education bureaucracy, schools in rural areas also implement health protocols and shorten teaching and learning time in class, even though the community in the school environment considers pandemics to be a natural reality.AbstrakPenelitian ini bertujuan untuk mengetahui respons masyarakat terhadap pandemi dan praktik pembelajaran masa pandemi pada anak petani pedalaman Aceh Selatan. Penelitian ini menggunakan pendekatan kualitatif dengan model deskriptif. Data diperoleh dari hasil observasi, wawancara, dan studi literatur yang relevan, kemudian dianalisis data, peneliti akan menggunakan teknik analisis interaktif. Hasil penelitian ini menunjukkan bahwa 1) Persepsi risiko masyarakat terhadap pandemi tergolong rendah, namun masyarakat tetap merespons pandemi ini dengan baik yaitu mematuhi protokol kesehatan dengan menggunakan masker ketika keluar menuju ke tempat-tempat umum. 2) Kegiatan pembelajaran anak-anak masyarakat petani pedalaman yang ada di Kluet Tengah berlangsung seperti biasa. Sebagaimana sekolah lainnya yang patuh pada birokrasi pendidikan, maka sekolah di pedalaman juga menerapkan protokol kesehatan dan mempersingkat waktu belajar mengajar di dalam kelas, meskipun masyarakat dilingkungan sekolah tersebut menganggap pandemi sebagai realitas yang biasa.

Keefektivan Pembelajaran Secara Online Terhadap Perkembangan Fisik Motorik Anak

The problem in this research is that in the online learning process the teachercannot monitor the physical development of the child's motor skills, because children studyat home and at home, the children cannot freely leave the house to play or go recreation.As a result, many parents think that playing cellphones is the main solution. The purposeof this study was to determine the effectiveness of online learning on motoric physicaldevelopment. The benefits of this research are expected to provide insight, boththeoretically and practically, for researchers in accordance with the focus of the researchbeing carried out. This research is a descriptive study, while the research information is asource of reference as well as previous research. Data collection was carried out by meansof observation, interview and documentation techniques. The instrument used by theresearcher was a physical motor indicator. Data analysts use an interactive analysis modelby collecting data, reducing data, presenting data, and drawing conclusions. The results ofresearch on children's physical motor development during online learning have decreased.

Online Learning Problems in the Covid-19 Pandemic for English Education Students

During the Covid-19 pandemic, the teaching and learning process through an online system is one option that can deal with barriers to the teaching and learning process directly to avoid the spread of the virus. This study intends to analyze students’responses to the problems they face during the Covid-19 pandemic and how students deal with online learning during the pandemic. The background of this research is the experience of students with the problems they face during distance learning or online due to Covid-19 which requires students to follow government rules, namely doing distance learning or online. The informants or respondents in this study were several students majoring in . The data collected by the researcher was based on online interviews conducted with 15 students The data analysis used interactive analysis technique by Miles Hubberman. The researcher arranges several questions that must be asked of the participants to obtain the required information. In the online teaching and learning process during the covid-19 pandemic, various problems experienced by students are as follows, the most dominant problem when carrying out online learning is the limited internet network, especially for students who live in rural areas.

EVALUASI PEMBINAAN TIM FUTSAL SMP NEGERI 4 PAKEM DAERAH ISTIMEWA YOGYAKARTA

ABSTRAKPenelitian ini bertujuan untuk mengevaluasi pembinaan tim futsal SMP Negeri 4 Pakem Daerah Istimewa Yogyakarta. Evaluasi dilakukan untuk mengetahui keefektifan pembinaan tim futsal SMP Negeri 4 Pakem. Jenis penelitian yang digunakan adalah penelitian evaluasi dengan menggunakan model CIPP. Pendekatan yang digunakan dalam penelitian ini yaitu pendekatan kualitatif dengan model analisis interaktif dari Miles Huberman. Teknik pengumpulan data menggunakan metode wawancara, observasi, dan dokumentasi. Subjek penelitian adalah 3 orang yang terdiri dari pengurus, pelatih, dan atlet dari SMP Negeri 4 Pakem. Hasil penelitian menunjukkan bahwa pembinaan tim futsal SMP Negeri 4 Pakem pada evaluasi context masuk kategori cukup. Evaluasi input pada pelaksanaan program pembinaan tim futsal SMP Negeri di Kabupaten Sleman Daerah Istimewa Yogyakarta masuk kategori baik. Evaluasi process pada pelaksananaan tim futsal SMP N 4 Pakem masuk kategori cukup. Evaluasi product pada pembinaan tim futsal SMP N 4 Pakem Daerah Istimewa Yogyakarta masuk kategori cukup.Kata Kunci: evaluasi, pembinaan, tim futsal.ABSTRACTThis study aimed to evaluate the development of futsal teams in SMP N 4 Pakem, Yogyakarta Special Region. The evaluation was carried out to find out its effectiveness. This was an evaluation research study using the CPP model. The approach used in the study was a qualitative approach with an interactive analysis model from Miles and Huberman. The data were collected through interviews, observations, and documentation. The research subjects were 3 people consisting of administrators, coaches, and athletes from SMPN 4 Pakem.The results of the study show that the development of the State Junior High School futsal team in SMP N 4 Pakem in the results of the context are moderate. The results of the input evaluation on the implementation of the development program are good. The results of the process evaluation on the implementation of the development program are moderate. The product evaluation on the development program are moderateKeywords: evaluation, development, futsal team

Preparation and Self-Efficacy of Science Student Teachers to Teach in English

The aim of this study was to examine the preparation of science student teachers before teaching in English, and to determine their self-efficacy in teaching in English. Data were collected using the triangulation method, through questionnaires, interviews, and documentation studies on student teacher practicum portfolios. This was a descriptive qualitative study and data were analyzed using the interactive analysis method of Miles and Huberman (1984) which has three components of analysis, namely data reduction, data presentation, and drawing conclusions or verification. The results showed that there were 6 preparations made by science student teachers before teaching in English: 1) determine the topic of the material being taught and look for the material; 2) study the subject matter in depth; 3) compile lesson plans in English; 4) prepare tools and materials for teaching including handouts, props, demonstrations, and science practicum; 5) search for common terminology in science related to the topic being taught; 6) practice teaching science in English, namely doing teaching exercises in English. The results also showed that the science student teachers’ level of self-efficacy in teaching science in English varied from low to high: 45.8% had high self-efficacy levels; 39.5% had moderate levels; and 9.0% had low self-efficacy. Keywords: self-efficacy, science student teacher, teaching preparation, readiness

Community Response to Village Information System (SID) in Basic Services In East Lombok Regency

This study aims to determine the public's response to use SID as a medium for basic social services, SID as a source of information, and SID as a community medium. This research can provide information about the readiness of the community to face the 4.0 revolution era, especially people in rural areas. If the community is ready and accustomed to using SID as a basic social service center and the other hand, managing resources continue to increase their capacity both in human resources and infrastructure, then SID can become a reliable database and can provide basic social services one-stop service in the village. This study used a qualitative descriptive method, data collecting on informants was carried out using in-depth interviews, direct observation, sampling techniques, documentation, and FGD. Then simultaneously carried out data analysis with interactive analysis methods. Key informants were the Village Head and SID Managers in Rarang Selatan and Kalijaga Timur Villages; as well as informants from village residents as many as 50 informants each 25 informants per village (consisting of elements of teachers, students, agricultural extension workers, heads of farmer groups, farmers, heads of farmer groups, Posyandu cadres, hamlet heads, housewives, traders). The results showed that the public response to SID as a service medium was positive, as a source of information was positive, and as a community medium was positive. This is shown by the behavior of the community using SID intensively, participating in disseminating the existence of SID, inviting villagers to take advantage of SID, even taking part in providing information (filling in content) to be conveyed to the community (especially village communities) through SID.Keywords: Response, Village Information System (SID), resources, community media, basic social services

Service Innovation for Route Permits and Public Transport Operations Permits through Si Pintar Solo at the Surakarta City Department of Transportation

Innovation is one way to restructure public services that are integrated with information technology. Starting from the existence of public transportation in the city of Surakarta that is no longer extending due to the revitalization of public transportation, the lack of network and route permits optimization and manual public transport permit services seem convoluted, slow and take a lot of time. The Surakarta City Department of Transportation created ‘Si Pintar Solo’ innovation, which is the the Solo Route and Operation Licensing Information System. This study aims to identify and understand the implementation of the Si Pintar Solo innovation by using the innovation theory according to Rogers (2003). This is a descriptive qualitative research, with primary data, such as interviews and secondary data from related documents. The sample selected by purposive sampling. The data validity used source triangulation. The data analyzed using interactive analysis. The results showed that the implementation of the Si Pintar Solo innovation described in each of the innovation attribute criteria, such as simplifying and accelerating services because it is supported by adequate facilities and infrastructure, according to community needs. Licensing is conducted online which does not require coming to the Surakarta City Department of Transportation office and is integrated with the e-Uji service. In addition, it could monitor the licensing process and the result of licensing data is stored in the database. However, there are obstacles, such as signal limitedness and the users’ quandary about innovations involving technology.