scholarly journals Allergenic Sensitization to pollen extracts in allergic patients. General “Calixto García” University Hospital, 2017.

2020 ◽  
Author(s):  
Belkis López González ◽  
Jorge Torres Concepción ◽  
Teresa Irene Rojas Flores ◽  
Mirta Àlvarez Castelló ◽  
Yaquelin Leyva Márquez ◽  
...  

Abstract Background: Nowadays, the allergic diseases are affecting the population at worldwide level and Cuba does not escape to this, inside the aeroallergens that trigger the crises we can find the pollens. The main goals of this study were to determine the allergenic sensitization to pollens in allergic patients and their relationship with the presence of allergic diseases.Methods: A cross-sectional descriptive observational study was performed in patients suffering from asthma, rhinitis, allergic rhino-conjunctivitis, atopic dermatitis and allergic conjunctivitis. All patients underwent an allergic clinical history and skin prick test with allergenic extracts of Helianthus annus, Cosmos bipinnatus, Cynodon dactylon, Quercus sp, Eucalyptus sp . Frequencies and percentages were determined for its analysis.Results: Thirty-three patients were studied. The average age was found in the third decade of life, with a predominance in women. More than half of the patients were sensitized to pollens and 24.24% of them were polysensitized; the most frequent pollen was the cynodon dactylon . The patients with rhinitis were the most sensitized with the pollens.Conclusions: There is sensitization to pollen in our patients.

Author(s):  
Montaha AL-Iede ◽  
Abdallah Al-Ani ◽  
Baraa Mafrachi ◽  
Dana Al-Khulaifat ◽  
Kamal Hassan ◽  
...  

Background: As the prevalence of allergic diseases is increasing all over the world, it is vital to identify the specific allergens which contribute to the development and persistence of such conditions. Objectives: This study aims to assess the prevalence of aeroallergen sensitization and, to evaluate the profile of skin prick test among atopic Jordanian children who are visiting Jordan University Hospital (JUH). Methods: A retrospective analysis of all Skin Prick Test (SPT) results of atopic children and adolescents aged (1.5-18 years) who were seen at the pediatrics clinics at JUH from January 2018 until December 2019. Results: Over two years, a total of 171 children (male: female ratio of 1.9) with a median age of 6.2 years (1.5-18) were subjected to SPT. One hundred and seven children (62.5%) were found to be sensitized to at least one of the ten aeroallergen extracts tested. The most common sensitizations were to olive pollen (45.6%), Mites Dermatophagoides Petronyssinus (42.0%), and Dog Dander (38.6%). The highest sensitization rate was among the age group 2-4 years (28.1%). The sensitization rates increased in conjunction with an increase in age in the first age groups (preschool and school-age groups). Conclusion: The study’s findings provide an understanding of the locally prevalent aeroallergens, yet a multi-center review would be more useful for creating an optimized SPT panel specific to the Jordanian pediatric population.


2018 ◽  
Vol 44 (1) ◽  
pp. 31-35 ◽  
Author(s):  
Martín Bedolla-Barajas ◽  
Norma Angélica Pulido-Guillén ◽  
Bolívar Vivar-Aburto ◽  
Jaime Morales-Romero ◽  
José Raúl Ortiz-Peregrina ◽  
...  

ABSTRACT Objective: To investigate whether there is an association between suicidal ideation (SI) and allergic diseases in adults. Methods: This was a comparative cross-sectional study involving individuals ranging from 20 to 50 years of age recruited from a university hospital in the city of Guadalajara, Mexico. We included patients with a confirmed diagnosis of allergic asthma, those with a confirmed diagnosis of allergic rhinitis, and healthy controls. All subjects completed the Beck Depression Inventory-II (BDI-II), which includes an item that evaluates the presence of suicidal thoughts or desires within the last two weeks, in order to identify SI. Results: The sample comprised 115 patients with allergic asthma, 111 patients with allergic rhinitis, and 96 healthy controls. The number of individuals identified with SI in the three groups were, respectively, 17 (14.8%), 13 (11.7%), and 8 (8.3%). Regarding the presence of SI, no statistically significant association was found in the allergic asthma group (OR = 1.98; 95% CI: 0.78-4.64; p = 0.154) or in the allergic rhinitis group (OR = 1.46; 95% CI: 0.58-3.68; p = 0.424) when they were compared with the control group. However, the presence of depression was associated with SI in the three groups: allergic asthma (OR = 12.36; 95% CI: 2.67-57.15; p = 0.001); allergic rhinitis (OR = 6.20; 95% CI: 1.66-23.14; p = 0.006); and control (OR = 21.0; 95% CI: 3.75-117.36; p < 0,001). Conclusions: In comparison with the control group, no association was found between SI and the groups with allergic diseases. In contrast, there was association between SI and depression in the three groups.


Author(s):  
Nasrin Pazoki ◽  
Ali Ahmadi ◽  
Fatemeh Onsori ◽  
Mohsen Mosavi Khorshidi ◽  
Mahboubeh Mansori ◽  
...  

Background and Aims: Identification of different allergens is a major challenge in allergic diseases. Avoiding these allergens is known as one of the best types of treatment. The aim of this study is to determine the prevalence of aeroallergens and food allergens in patients with allergy by Skin Prick Test. Materials and Methods: A cross-sectional study was conducted on 255 patients with allergic diseases who had referred to the Khorshid Allergy and Immunology Clinic. Skin Prick Test was performed using 82 allergen extracts to determine the patients' sensitivity to food and aeroallergens. Results: One hundred percent of the patients were sensitive to at least one allergen. Allergy to food allergens and aeroallergens was 49% and 51 %, respectively. Most sensitivity to food allergens included hazelnut (26.27%), bananas (21.96%), egg yolk (21.56%) and wheat (20.39%). Among the aeroallergens, grass with a frequency of 87% and fungi with a frequency of 34% had the highest and lowest frequencies. Conclusion: Depending on the nutrition, cultural habits, environmental conditions, and life style, prevalence of the allergens in each area may be different. Therefore, early identification and avoidance from these allergens can be suggested.


2021 ◽  
Vol 19 (2) ◽  
Author(s):  
Youssef A. Alqahtani ◽  
Ayed A. Shati ◽  
Ahmad A. Alhanshani ◽  
Bayan M. Hanif ◽  
Eman S. Salem ◽  
...  

Background: Food allergy (FA) is increasingly recognized with the highest prevalence in preschool children; there has been a significant increase in hospital admissions for systemic allergic diseases with anaphylaxis and food allergies. Hospital admissions for food allergy were noticed to rise from 6 to 41 per million between 1990 and 2000 worldwide . The prevalence of food allergy is increasing over time with significant geographic variations. It is estimated to affect 6% of children in the United States (USA); according to a study conducted in Makkah, by AL Mokarmah, the prevalence of FA among children attending the well-baby clinic was 22.5% and in Riyadh is 6% among children who visit the allergy clinic at King Khalid University Hospital. FA in children is usually caused by milk (2.5%), egg (1.3%), peanut (0.8%), tree nuts (0.2%), fish (0.1%), as well as shellfish (0.1%), with an overall prevalence of 6%. Methods: In this cross-sectional study, a self-administered questionnaire was used in the data collection. After data were collected, they were entered in the Statistical Software IBM SPSS version 22. Descriptive and inferential statistics were obtained. Results: Out of 980 mothers, 49% were suffering from food allergy, while 28.6% of their children were suffering from food allergy. Shellfish was the most common cause of food allergy (38%). Conclusion: The management of FA in children is improving through the acquisition of new knowledge in diagnosis and treatment. Education of physicians and food-allergic patients about FA and its treatment is becoming recognized as an unmet need. Key words: Food allergy, mother, children, knowledge, prevalence, factors


PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257721
Author(s):  
Mayako Saito-Abe ◽  
Kiwako Yamamoto-Hanada ◽  
Kensuke Shoji ◽  
Miori Sato ◽  
Makoto Irahara ◽  
...  

Background The relationship between allergic individuals and their responsiveness to routine vaccines has rarely been investigated. This study examined whether the seroprevalence of measles antibody differed between children with and without allergic diseases in the general pediatric population. Methods The cross-sectional study was performed within a prospective general birth cohort (a pilot study of the Japan Environment & Children’s Pilot Study [JECS]) of children aged 8 years. The clinical history of allergic diseases, measles, and the concentration of measles immunoglobulin G titers in serum enzyme immunoassay were examined. Fisher’s exact tests were used to assess the relationships between the allergic characteristics of the children and their measles antibody positivity rates. Results This study included 162 children. Any allergic disease was reported in 75 (46.3%). The measles antibody positivity rate was 94.7% among children with any allergic diseases and 92.0% among children without allergic diseases. Our results revealed no differences in measles antibody seropositivity between children with allergies and controls. Conclusions Children with allergies mount and maintain a comparable immune response to the measles vaccine.


2014 ◽  
Vol 54 (1) ◽  
pp. 52
Author(s):  
Schenny Regina Lubis ◽  
Lily Lrsa ◽  
Rita Evalina ◽  
Supriatmo Supriatmo ◽  
M. Sjabaroeddin

Background Allergic diseases cause an increasingly largeburden in developed countries and in urban areas of middleincomecountries . Paras itic infections may induce allergicresponses in humans, particularly soil-transmitted helminth(STH) infections that are prevalent in childhood in developingcountries. Although soil-transmitted helminth infec tions havebeen associated with lower prevalence of allergen skin testreactivity, study outcomes remain inconclusive.Objective To analyze for an association between STH infectionsand skin prick test reactivity in children.Methods We conducted a cross-sectional study in August 2009among primary school students aged 7- 12 years, at SecanggangSubdistrict, Langkat District, North Sumatera Province. Sixtyeight children were recruited in this study consisted of 34 childrenwith STH infections and the other 34 children without any STHinfection. Soil-transmitted helminth infections were determinedby Kato-Katz stool examination s. All subjects underwent skinprick tests for seven allergens. Results were con sidered to bepositive if wheal diameters 2: 3 mm and negative when whealdiameters < 3 mm. Data was an alysed by Chi-square test.Results Stool examinations revealed that the most commoninfec tion was T. trichiura (18/34 subjects), followed by mixedinfections (T. trichiura and A lumbricoides; 12/34 subjects), andA. lumbricoides (4134 subjects). There was a significant associationbetween STH infections and negative skin prick test (P= 0.002).In addition, there were significant associations with negative skinprick tests for each helminth type: A. lumbricoides (P=0.001) ,T. trichiura (P=0.01) and mixed infection (P = 0.006). Severeinfection intensity was also significantly associated with negativeskin prick tests (P=0.031) .Conclusion Children with STH infections tend to have negativeskin prick test results.


2012 ◽  
Vol 20 (6) ◽  
pp. 1072-1080 ◽  
Author(s):  
Daniela Cavalcante de Negri ◽  
Ariane Ferreira Machado Avelar ◽  
Solange Andreoni ◽  
Mavilde da Luz Gonçalvez Pedreira

OBJECTIVE: To identify predisposing factors for peripheral intravenous puncture failure in children. METHODS: Cross-sectional cohort study conducted with 335 children in a pediatric ward of a university hospital after approval of the ethics committee. The Wald Chi-squared, Prevalence Ratio (PR) and backward procedure (p≤0.05) tests were applied. RESULTS: Success of peripheral intravenous puncture was obtained in 300 (89.5%) children and failure in 35 (10.4%). The failure rates were significantly influenced by: presence of clinical history of difficult venous access, malnourishment, previous use of peripherally inserted central venous catheter, previous use of central venous catheter, and history of phlebitis or infiltration. In the multivariate model, being malnourished and having previously been submitted to central venous catheterization were the predisposing factors for the failure. CONCLUSION: The failure rate of 10.4% is similar to that identified in analogous studies and was influenced by characteristics of the children and intravenous therapy. In association with this, malnutrition and previous use of a central venous catheter were the most important variables influencing increase in peripheral intravenous puncture failure.


2021 ◽  
Vol 4 (1) ◽  
pp. 85-88
Author(s):  
Dr. K Pavan Kumar ◽  
Dr. RSV Srikrishna ◽  
Dr. Indira Pavan ◽  
Dr. M Surendranath ◽  
Dr. Major Nagaraju

2021 ◽  
Author(s):  
Yang Yie Sio ◽  
Sze Lei Pang ◽  
Yee-How Say ◽  
Keng Foo Teh ◽  
Yi Ru Wong ◽  
...  

AbstractFungal spores and conidia are the major components of total airspora in the tropical Asia environment, and their sensitization patterns are often associated with allergic diseases such as asthma, allergic rhinitis (AR), and atopic dermatitis. Hence, we recruited a cross-sectional cohort of 9223 Singapore/Malaysia Chinese adults and assessed their sensitization against Curvularia lunata allergen using the skin prick test approach. A subset of this cohort (n = 254) was also screened for specific Immunoglobulin E (sIgE) titers against a panel of 11 fungal allergens. We found significant association of Curvularia lunata sensitization with the risk of asthma (OR = 1.66, 95% CI: 1.17–2.33; p = 0.00391) and AR (OR = 1.69, 95% CI: 1.18–2.41; p = 0.00396). Among asthmatic patients (n = 1680), Curvularia lunata sensitization also increased frequencies of wheezing symptoms (OR = 1.81, 95% CI: 1.05–2.96; p = 0.0239), general practitioner/specialist visits (OR = 2.37, 95% CI: 1.13–4.61; p = 0.0157), and other asthma-related exacerbation events (OR = 2.14, 95% CI: 1.04–4.10; p = 0.0289). In our serum cohort, sensitization to Aspergillus spp. was the most common fungal sensitization, with 23.6% (n = 60) had a class 3 and above sensitization (positive sensitization; sIgE titers of > 3.5 kU/L) against this allergen. Increasing sIgE titer against Aspergillus spp. was also correlated with increased AR risk and AR-related symptoms. In conclusion, our findings emphasize an important role of fungal sensitization in the manifestations of asthma and AR in the Southeast Asian Chinese population.


2016 ◽  
Vol 56 (4) ◽  
pp. 221
Author(s):  
Afnita Lestary ◽  
Lily Irsa ◽  
Tiangsa Sembiring ◽  
Rita Evalina ◽  
Meiviliani Sinaga

Background Prevalence of atopy, allergic diseases, and obesity are increasing. Atopy is an individu and/or familial tendency to sensitization in response to ordinary exposure to allergens. Obesity is defined as body mass index (BMI) greater or equal to 95 percentile. Research on association of BMI with atopy and allergic diseases in children were limited, with inconclusive results. Objective To assess association of BMI with atopy and allergic diseases in chidren.Methods A cross-sectional was conducted in school children aged 6-12 years in Lhokseumawe City, Aceh, June 2012. Children were assessed for BMI, skin prick test, and  International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Statistical analyses included Chi-square, Fisher exact, and logistic regression.Results Children consisted of 137 (85.6%) normoweight, 12 (7.5%) overweight, and 11 (6.9%) obesity. Skin prick test results were positive in 44 (27.5%) and negative in 116 (72.5%) subjects. Allergic manifestations were allergic rhinitis (AR) 17 (10.6%), bronchial asthma 6 (3.8%), and atopic dermatitis (AD) 3 (1.9%). There was significant association of obesity with atopy, compared with normoweight (OR=3.78; 95%CI 1.08 to 13.19; P=0.037), but no significant association found when family history of atopy also assesed. There was significant association of obesity with bronchial asthma (OR=9.92; 95%CI 1.46 to 67.18; P=0.004) and AR (OR=6.49; 95%CI 1.64 to 25.66; P=0.015), compared with normoweight. Significant association of overweight with atopy and allergic disease was not found.Conclusion Obesity significantly associates with atopy, bronchial asthma, and AR, but overweight and normoweight  do not.  


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