scholarly journals Paediatric Eyelid Lesions- A Report of 20 Cases

2020 ◽  
Vol 7 (10) ◽  
pp. A509-513
Author(s):  
Pragati Sathe ◽  
Ankita Asthana
Keyword(s):  
Histopathological Examination ◽  
Wide Spectrum ◽  
Tertiary Hospital ◽  
Malignant Neoplasms ◽  
Institutional Ethics ◽  
Eyelid Swelling ◽  
Benign Nature ◽  
Upper Lid ◽  
The Common ◽  
Eyelid Lesions

Background: Eyelid lesions are one of the commonest lesions encountered by ophthalmologists in their clinical practice. They could be classified in various ways such as neoplastic or non-neoplastic; congenital or acquired. The common benign conditions affecting the eyelid include cysts like dermoid, epidermoid and epithelial cysts, inflammatory lesions, melanocytic nevi and papilloma. Ignorance about the benign nature of the lesion may lead to increased debility. The purpose of this study is to contribute information to the literature on various eyelid lesions and their incidence as found in a tertiary hospital. Methods: This is a retrospective observational study of surgically excised eyelid lesions in patients below 12 years of age. The study was conducted after obtaining permission from the Institutional Ethics Committee. Result: Out of 20 lesions, 15 cases belonged to the non-neoplastic category while five cases were neoplastic in nature. Cystic lesions predominated in the non-neoplastic category (11 out of 15 cases). The remaining four cases in the non-neoplastic category included three cases of infective etiology and one case of developmental etiology. There were no malignant neoplasms found in our study. The common presenting feature was that of eyelid swelling. Highest incidence of eyelid lesions was in the upper lid (14 of 20 cases, i.e. 66.66%). Conclusion:  It is necessary to subject every lesion of the eyelid to histopathological examination. Sometimes, clinically benign lesions turn out to be malignancies which entails a wider surgery later. This study points out to the wide spectrum of lesions that can afflict the eyelid. 

scholarly journals Lesions of pinna in a tertiary care hospital in Dakshina Kannada

Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 560-564
Author(s):  
D. Deviprasad ◽  
Meera N. Khadilkar ◽  
U. Anand Kini ◽  
Suja Sreedharan ◽  
Shenoy S. Vijendra
Keyword(s):  
Soft Tissue ◽  
Tertiary Care Hospital ◽  
Histopathological Examination ◽  
Wide Spectrum ◽  
Tertiary Care ◽  
Surgical Excision ◽  
Epidermal Cyst ◽  
Care Hospital ◽  
Institutional Ethics ◽  
Seborrhoeic Keratosis

Introduction and Aim: Most of the lesions affecting pinna are cutaneous conditions. Those arising from the cartilage are extremely rare, whereas those from the soft tissue like vascular, stromal and adnexal components are relatively common. The present study aims at analysing the proportion, types, and categories of lesions affecting the pinna. Methods: Following institutional ethics committee approval, a retrospective analysis of medical records of 40 patients who underwent surgical excision of pinna lesions from 2006 to 2018 was conducted at a tertiary care hospital in Dakshina Kannada, India. Lesions were grouped as benign adnexal, benign soft tissue, malignant lesions, and infection/inflammation. Results: Median age was 47.5 years and mode was 59 years. There were thirty (75%) males and ten (25%) females. The commonest lesions included epidermal cyst (25%), followed by seborrhoeic keratosis (17.5%), and squamous cell carcinoma (10%). Conclusion: A wide spectrum of entities affecting the pinna were encountered in the present study. Superficial cystic lesions are the most frequent type found in pinna and are amenable to simple excision. Benign neoplasms require surgical intervention; malignancy is also to be kept in mind while making a clinical diagnosis, necessitating wide clearance with or without neck dissection. Early intervention and confirmation of diagnosis by histopathological examination helps not only in successful management but also in preventing disfigurement and psychosocial complications.

scholarly journals Histopathological Analysis of Endometrial Biopsy in Gandaki Medical College Teaching Hospital, Pokhara, Nepal

2019 ◽  
Vol 12 (1) ◽  
pp. 25-30
Author(s):  
B Parajuli ◽  
G Pun ◽  
S Ranabhat ◽  
S Poudel
Keyword(s):  
Histopathological Examination ◽  
Hydatidiform Mole ◽  
College Teaching ◽  
Histopathological Diagnosis ◽  
Age Group ◽  
Medical College ◽  
Dilatation And Curettage ◽  
Partial Mole ◽  
Proliferative Endometrium ◽  
The Common

Objective: To study the spectrum of histopathological diagnosis of endometrial lesions and their distribution according to age. Methods: All the endometrium samples obtained by the procedure of dilatation and curettage and hysterectomy sent for histopathological examination at Pathology Department of Gandaki Medical College Teaching Hospital, Pokhara, Nepal. The study duration was total 12 months ranging from July 2016 to June 2017. All the endometrial samples were processed, sectioned at 4 - 6 μm and stained with routine H & E stain. Patient’s data including age, sex, procedure of the biopsy taken and histopathological diagnosis were noted. A pathologist, using Olympus microscope, reported the slides. Cases were reviewed by a second pathologist whenever necessary. Results: A total of 128 cases were studied. The most common histopathological diagnosis was proliferative endometrium (28.9%) followed by disorder proliferative endometrium (15.65%). Most of the patients were in age group 36 - 45 years comprising 32.03%. Hydatidiform mole comprised of 7.03% and among Hydatidiform mole, partial mole was more common. Dilatation and curettage (82.8%) was the common procedure in compare to hysterectomy for the evaluation of endometrial lesions. Conclusions: In this study, we observed a variety of endometrial lesions. Most of them are benign; among benign, proliferative endometrium was the common histopathological diagnosis followed by disorder proliferative endometrium. Most common presenting age group was found to be at 36 - 45 years. In evaluation of hydatidiform mole, partial mole was more frequent in compare to complete mole. Conventional dilatation and curettage is the preferred method in developing countries with limited resource to screen endometrial lesion and therefore biopsy should be sent for histopathological examination. Thus histopathological examination of routinely stained hematoxylin and eosin is readily available and widely accepted standard technique for evaluation of the endometrial lesions.

Decrease in proven ventriculitis by reducing the frequency of cerebrospinal fluid sampling from extraventricular drains

2011 ◽  
Vol 115 (5) ◽  
pp. 1040-1046 ◽  
Author(s):  
Teresa A. Williams ◽  
Gavin D. Leslie ◽  
Geoffrey J. Dobb ◽  
Brigit Roberts ◽  
Peter Vernon van Heerden
Keyword(s):  
Head Injuries ◽  
Tertiary Hospital ◽  
Sampling Frequency ◽  
Apache Ii Score ◽  
Optimum Frequency ◽  
Clinical Indicators ◽  
Historical Comparison ◽  
Institutional Ethics ◽  
Daily Sampling ◽  
Definition Of

Object Ventriculitis associated with extraventricular drains (EVD) increases rates of morbidity and mortality as well as costs. Surveillance samples of CSF are taken routinely from EVD, but there is no consensus on the optimum frequency of sampling. The goal of this study was to assess whether the incidence of ventriculitis changed when CSF sampling frequency was reduced once every 3 days. Methods After receiving institutional ethics committee approval for their project, the authors compared a prospective sample of EVD-treated patients (admitted 2008–2009) and a historical comparison group (admitted 2005–2007) at two tertiary hospital ICUs. A broad definition of ventriculitis included suspected ventriculitis (that is, treated with antibiotics for ventriculitis) and proven ventriculitis (positive CSF culture). Adult ICU patients with no preexisting neurological infection were enrolled in the study. After staff was provided with an education package, sampling of CSF was changed from daily to once every 3 days. All other management of the EVD remained unchanged. More frequent sampling was permitted if clinically indicated during the third daily sampling phase. Results Two hundred seven patients were recruited during the daily sampling phase and 176 patients when sampling was reduced to once every 3 days. The Acute Physiology and Chronic Health Evaluation (APACHE) II score was lower for the daily sampling group than for the every-3rd-day group (18.6 vs 20.3, respectively; p < 0.01), but there was no difference in mean age (47 and 45 years, respectively; p = 0.14), male or female sex (61% and 59%, respectively; p = 0.68), or median EVD duration in the ICU (4.9 and 5.8 days, respectively; p = 0.14). Most patients were admitted with subarachnoid hemorrhage (42% in the daily group and 33% in the every-3rd-day group) or traumatic head injuries (29% and 36%, respectively). The incidence of ventriculitis decreased from 17% to 11% overall and for proven ventriculitis from 10% to 3% once sampling frequency was reduced. Sampling of CSF once every 3 days was independently associated with ventriculitis (OR 0.44, 95% CI 0.22–0.88, p = 0.02). Conclusions Reducing the frequency of CSF sampling to once every 3 days was associated with a significant decrease in the incidence of ventriculitis. The authors suggest that CSF sampling should therefore be performed once every 3 days in the absence of clinical indicators of ventriculitis. Reducing frequency of CSF sampling from EVDs decreased proven ventriculitis.

INCIDENTAL GALL BLADDER CARCINOMA (IGBC) IN CHOLECYSTECTOMY SPECIMENS REMOVED FOR CHOLELITHIASIS

2021 ◽  
Vol 5 (10) ◽  
Author(s):  
Dharmpal Godara ◽  
Vijay Pal Singh Dhayal
Keyword(s):  
Gall Bladder ◽  
Bladder Carcinoma ◽  
Histopathological Examination ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Survival Outcome ◽  
Sectional Study ◽  
Gall Bladder Carcinoma ◽  
Cross Sectional ◽  
Hospital Records

Background: The present study highlights the occurrence of Incidental gallbladder carcinoma (IGBC) detected during histopathological examination in cholecystectomy specimens removed for cholelithiasis. Methods- This is a tertiary hospital based cross-sectional study of 500 cholecystectomy specimens removed during cholelithiasis. Relevant hospital records, histopathology slides and reports were reviewed, re-evaluated and studied. Results: 4(0.80%) cases of incidental gall bladder carcinoma (IGBC) were diagnosed from the histopathological evaluation (HPE) of 500 cholecystectomy specimens, constituting 0.80% of gall bladder specimens received during the study period. The age of the patients with IGBC ranged from 51-80 years. More females were affected than males with a M:F ratio of 1:3. Conclusion: Early detection of IGBC by histopathological examination would have a favourable impact on prognosis and management thereby increasing the survival outcome. Keywords: Cholelithiasis, Incidental Gall Bladder Carcinoma

scholarly journals Lymphadenopathy : Histopathological evaluation of 90 Cases in Chittagong

2015 ◽  
Vol 14 (1) ◽  
pp. 19-21
Author(s):  
Md Babul Osman Chowdhury ◽  
ASM Mostaque Ahmed ◽  
Abhijit Chowdhury
Keyword(s):  
Hodgkin Lymphoma ◽  
Histopathological Examination ◽  
International Studies ◽  
Gold Standard Method ◽  
Medical College ◽  
Non Hodgkin Lymphoma ◽  
Common Clinical Presentation ◽  
The Common ◽  
Tissue Specimens ◽  
Reactive Hyperplasia

Lymphadenopathy is one of the common clinical presentation of patients suffering from different disease processes. Lymphnode enlargement may be due to reactive changes, tuberculosis, sarcoidosis, Hodgkin lymphoma, Non Hodgkin lymphoma, Metastatic deposits etc. Histopathological examination of the enlarged lymphnode is the gold standard method to ascertain the cause of the enlargement. The objective of our study was to explore the causes of lymphadenopathy in the population of Chittagong. The study was conducted in the department of Pathology, Chattagram Maa-O-Shishu Hospital Medical College, Chittagong during January 2012 to July 2014. A total of 90 (Ninety) lymphoid tissue specimens were received and Hematoxilin Eosin stained histopathological slides were prepared and microscopic examination was done. The most common morphologic changes of lymphadenopathy noted was reactive hyperplasia (36.66%) and other causes included were tuberculosis (27.77%), metastasis (20%), Non-Hodgkin lymphoma (7.77%), Hodgkin lymphoma (4.44%) and suppurative lymphadenitis (3.33%). Our observations are supported by some other national and international studies on lymphadenopathy.DOI: http://dx.doi.org/10.3329/cmoshmcj.v14i1.22874 Chatt Maa Shi Hosp Med Coll J; Vol.14 (1); Jan 2015; Page 19-21

scholarly journals Visual loss from mismanaged ocular injury with foreign body impaction: A Case Report

2018 ◽  
Vol 4 (2) ◽  
pp. 198-204
Author(s):  
Ifedayo O. Akintoye ◽  
Caroline O. Adeoti
Keyword(s):  
Foreign Body ◽  
Health Workers ◽  
Hospital Setting ◽  
Tertiary Hospital ◽  
Health Concern ◽  
Ocular Injury ◽  
Eye Injuries ◽  
Health Extension Workers ◽  
Foreign Body Impaction ◽  
Upper Lid

Ocular injury occurs commonly and it may lead to visual impairment if it is not properly managed. We report the case of a 35-year old man with a retained infected ocular foreign body in his right eye following an injury. The foreign body was not discovered despite consulting non-ophthalmologists at a Maternity Centre and an Optical Shop over a period of ten days.  At presentation at the Specialist Hospital, he was unable to see with swelling of the eyelid, red eye and discharge. On examination, the visual acuity in the affected eye was NLP and an infected stick that penetrated the eyeball was discovered in the superonasal aspect of sclera covered by the swollen upper lid. This resulted in endophthalmitis, cataract and blindness of that eye. Ocular injuries must be promptly referred to the ophthalmologist for appropriate care and to prevent complications. The case clearly showed a diagnostic and therapeutic challenge for paramedics who encounter eye injuries outside the tertiary hospital setting. Therefore, this report raises public health concern intended to increase awareness on the management of eye injuries. The incorporation of Primary Eye Health into Primary Health Care along with training and re-training of Community Health Extension Workers, General Practitioners and other rural health workers cannot be overemphasized.

scholarly journals Reversal of Ketamine Induced Acute Delirium with Continuous Midazolam Infusion in a Post Extubation Child with Refractory Bronchospasm: A Case Report

2020 ◽  
Vol 26 (2) ◽  
pp. 56-59
Author(s):  
Fahisham Taib ◽  
Laila Ab Mukmin
Keyword(s):  
Low Dose ◽  
Care Setting ◽  
Tertiary Hospital ◽  
Emergence Delirium ◽  
The Past ◽  
First Case ◽  
Midazolam Infusion ◽  
Standardized Treatment ◽  
Life Threatening ◽  
The Common

Continuous ketamine infusion has been used successfully to treat severe refractory bronchospasm in children requiring mechanical ventilation in the intensive care setting. One of the common side effects known is emergence delirium. There is no standardized treatment for the ketamine-induced emergence delirium although benzodiazepine, haloperidol and dexmedetomidine have been reported to be effective in the past. A 7-year-old girl admitted to a tertiary hospital for life-threatening asthma requiring immediate intubation and ventilation. Ketamine was used as sedative and bronchodilator in anticipation of her challenging ventilation strategy. She was successfully extubated on day 8 of admission, however, she developed symptoms associated with the delirium. Successful reversal of the symptoms was achieved after 48-hour use of low dose intravenous midazolam. This was the first case reported on the reversal of ketamine-induced emergence phenomenon using low dose intravenous midazolam infusion.

scholarly journals Varied presentations of cutaneous vasculitis: a case series

2020 ◽  
Vol 8 (8) ◽  
pp. 3066
Author(s):  
Pinky Gupta ◽  
Shweta Ganorkar ◽  
Surekha Bhalekar ◽  
Rajiv Rao
Keyword(s):  
Blood Vessels ◽  
Histopathological Examination ◽  
Wide Spectrum ◽  
Systemic Disease ◽  
Case Series ◽  
Clinical Severity ◽  
Cutaneous Vasculitis ◽  
Venous Stasis ◽  
Duration Of Symptoms ◽  
Organ Systems

Vasculitis involves a wide spectrum of clinicopathological process with reactive damage to the involved blood vessels. There is loss of vessel integrity instigating haemorrhage & luminal compromise leading to ischemia and necrosis of the tissue supplied by the involved vessels. It may affect varied size and type of blood vessels at different locations. It may be primary or secondary to systemic disease. It may involve a single organ like skin or may involve different organ systems at the same time. This case series include six cases of cutaneous vasculitis affecting different organs with varied presentations. Skin biopsies of six patients with unusual presentations were studied. Their complete history, physical examinations, laboratory investigations including serology were analysed and correlated with histopathological findings. The patients presented with different duration of symptoms varying from as short as 15 days to 1 year. Skin lesions were present in all cases while cardiac manifestation was seen in one. Serology and autoimmune disease markers were negative in all cases except one. However, histopathological features were in concordance with the clinical diagnosis of vasculitis. They were further classified as vasculitis secondary to Churg Strauss syndrome, venous stasis, Henoch Schonlein purpura or leucocytoclastic vasculitis.Vasculitis though a rare disease may manifest as an acute or chronic condition. It needs timely diagnosis by histopathological examination to aid in further management. It is important to assess the clinical severity in primary and secondary vasculitis, as it determines morbidity and mortality.

A Comparison between International Trade and R&D Collaboration Networks in the European Aerospace Sector

2016 ◽  
pp. 141-171
Author(s):  
Pier Paolo Angelini ◽  
Lucio Biggiero
Keyword(s):  
International Trade ◽  
Wide Spectrum ◽  
Collaboration Network ◽  
Final Conclusion ◽  
Collaboration Networks ◽  
Aerospace Sector ◽  
Problems And Solutions ◽  
Methodological Problems ◽  
The Common ◽  
International Trade Network

Do trading countries also collaborate in R&D? This is the question that, facing with a number of methodological problems, here it is dealt with. Studying and comparing the international trade network and the R&D collaboration network of European countries in the aerospace sector, social network analysis offers a wide spectrum of methods and criteria either to make them comparable or to evaluate its similarity. International trade is a 1-mode directed and valued network, while the EU-subsidized R&D collaboration is an affiliation (2-mode) undirected and unvalued network, and the elementary units of this latter are organizations and not countries. Therefore, to the aim to make these two networks comparable, this paper shows and discusses a number of methodological problems and solutions offered to solve them, and provides a multi-faceted comparison in terms of various statistical and topological indicators. A comparative analysis of the two networks structures is made at aggregate and disaggregate level, and it is shown that the common centralization index is definitively inappropriate and misleading when applied to multi-centered networks like these, and especially to the R&D collaboration network. The final conclusion is that the two networks resemble in some important aspects, but differ in some minor traits. In particular, they are both shaped in a core-periphery structure, and in both cases important countries tend to exchange or collaborate more with marginal countries than between themselves.

scholarly journals A Rare Case of Fibrous Hamartoma of Infancy: A Clinicopathological Diagnosis at a Tertiary Hospital, Eastern Nepal

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
G. Lama ◽  
P. Upadhyaya ◽  
B. Adhikari ◽  
M. Adhikari ◽  
S. Dhakal
Keyword(s):  
Histopathological Examination ◽  
Stellate Cell ◽  
Fibrous Tissue ◽  
Female Child ◽  
Tertiary Hospital ◽  
Fibrous Hamartoma Of Infancy ◽  
Myxoid Matrix ◽  
Proper Diagnosis ◽  
Gross Examination ◽  
Infants And Young Children

Background. Fibrous hamartoma of infancy is a rare soft tissue lesion of infants and young children with characteristic triphasic morphology. Case Description. An 18-month-old female child was presented with complaints of swelling over right leg shin since birth. On examination, a lump of size 7x3 cm was identified which was mobile and nontender. Local excision was performed and tissue sent for histopathological examination. On gross examination, a globular, capsulated, firm to hard tissue had cut section revealing solid grey-white to grey-brown lesion with myxoid areas identified. Microscopic examination revealed a poorly circumscribed lesion comprising intersecting trabeculae of fibrous tissue, areas of immature oval and stellate cell within myxoid matrix, and varying amounts of interspersed mature fat cells. Conclusion. Even though fibrous hamartoma of infancy is a rare benign entity with limited clinical knowledge, proper diagnosis is mandatory as its prognosis is excellent.

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