scholarly journals A symmetric hypocorrection of myopia by FemtoLASIK in patients with presbyopia

2018 ◽  
Vol 11 (4) ◽  
pp. 43-48 ◽  
Author(s):  
N. V. Khodzhabekyan ◽  
A. T. Khandzhyan ◽  
E. P. Tarutta
Keyword(s):  
Age Groups ◽  
Control Group ◽  
Age Group ◽  
Corneal Hydration ◽  
Flap Thickness ◽  
Group 3 ◽  
Group 2 ◽  
Possible Cause ◽  
Group 1

Purpose: to evaluate the results of symmetric binocular hypocorrection of myopia with FemtoLasik surgery in patients with presbyopia of various age groups.Material and methods. 33 patients (66 eyes) with myopic refraction, aged 36 to 50, were operated by FemtoLasik. The intended Femto Flap thickness was 100 μm. The patients were divided into three groups depending on age; group 1 included 16 patients (32 eyes) aged 39–44, group 2 had 12 patients (24 eyes) aged 45–50, and group 3 (controls) was composed of 5 patients (10 eyes) of pre-presbyopic age (36–38 years).Results. The symmetric binocular hypocorrection proved efficient in 35 % of cases in the group 1 and 50 % of cases in group 2. In the control group the intended and obtained values coincided in all 100 % of cases.Conclusion. A possible cause of the discrepancy between the intended and the obtained hypocorrection effect may be a reduced corneal hydration of patients older than 39 years.

scholarly journals Interaction Between Age and Change in Velocity During a Baseball Training Program

2020 ◽  
Vol 8 (6) ◽  
pp. 232596712092793
Author(s):  
Christopher Antonacci ◽  
Thomas R. Atlee ◽  
Peter N. Chalmers ◽  
Christopher Hadley ◽  
Meghan E. Bishop ◽  
...  
Keyword(s):  
Training Program ◽  
Age Groups ◽  
Maximum Velocity ◽  
Age Group ◽  
Significant Difference ◽  
Group 3 ◽  
Baseball Pitchers ◽  
Group 2 ◽  
The Relationship ◽  
Group 1

Background: Pitching velocity is one of the most important metrics used to evaluate a baseball pitcher’s effectiveness. The relationship between age and pitching velocity after a lighter ball baseball training program has not been determined. Purpose/Hypothesis: The purpose of this study was to examine the relationship between age and pitching velocity after a lighter ball baseball training program. We hypothesized that pitching velocity would significantly increase in all adolescent age groups after a lighter baseball training program, without a significant difference in magnitude of increase based on age. Study Design: Cohort study; Level of evidence, 2. Methods: Baseball pitchers aged 10 to 17 years who completed a 15-week training program focused on pitching mechanics and velocity improvement were included in this study. Pitchers were split into 3 groups based on age (group 1, 10-12 years; group 2, 13-14 years; group 3, 15-17 years), and each group trained independently. Pitch velocity was assessed at 4 time points (sessions 3, 10, 17, and 25). Mean, maximum, and mean change in pitch velocity between sessions were compared by age group. Results: A total of 32 male baseball pitchers were included in the analysis. Mean/maximum velocity increased in all 3 age groups: 3.4/4.8 mph in group 1, 5.3/5.5 mph in group 2, and 5.3/5.2 mph in group 3. While mean percentage change in pitch velocity increased in all 3 age groups (group 1, 6.5%; group 2, 8.3%; group 3, 7.6%), the magnitude of change was not significantly different among age groups. Program session number had a significant effect on mean and maximum velocity, with higher mean and maximum velocity seen at later sessions in the training program ( P = .018). There was no interaction between age and program session within either mean or maximum velocity ( P = .316 and .572, respectively). Conclusion: Age had no significant effect on the magnitude of increase in maximum or mean baseball pitch velocity during a velocity and mechanics training program in adolescent males.

scholarly journals ATTITUDES TOWARDS THE NAMES AND THE TASTES OF FOODS IN SONGKHLA PROVINCE, THAILAND

2019 ◽  
pp. 1
Author(s):  
Angsuviriya Angsuviriya ◽  
Chanokporn Chanokporn
Keyword(s):  
Ethnic Groups ◽  
Positive Attitude ◽  
Age Groups ◽  
Negative Attitude ◽  
The Other ◽  
Age Group ◽  
Buffalo Meat ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

The objective of this article is to study the attitudes of different age and ethnic groups reflected through the names and the taste of food, that is the southern Thais have a positive attitude towards more tasteful or the taste of hot than the other ethnic groups while the Chinese Thais they have a more positive attitude towards  insipid taste than the other ethnic groups. For the Malaysian Thais they have a more positive attitude towards the taste of sweet than the other two ethnic groups. As for main course dish, the most popular main course dishes in all the 3 groups are “Kangsom” (sour soup made of tamarind paste) and “KangTaipla” or “KangPhungpla”. As for dessert, the most favorite desserts in all the 3 groups are “Klauybuatchee” or Klauybuat (banana in coconut milk) and “Lotchong” or “Singaporean Lotchong”. In addition, it is found that the Chinese Thais and the southern Thais have a negative attitude towards beef, eels, buffalo meat etc, while the Malaysian Thais have a negative attitude towards pork because they are Muslim. When age groups have been taken into account, age group 1 (15-25) does not like spicy foods, compared with the other age group. While age group 2 (35-45) has similarities in the food names of those in age group 1 and age group 3; therefore, there are more food names in age group 2 than those in the other groups. In addition, for age group 3 (55 or more) more local names of foods are found.   Keywords: Attitudes, the names and the tastes of foods, the ethnic

scholarly journals A mathematical model for estimating the age-specific transmissibility of a novel coronavirus

2020 ◽  
Author(s):  
Ze-Yu Zhao ◽  
Yuan-Zhao Zhu ◽  
Jing-Wen Xu ◽  
Qing-Qing Hu ◽  
Zhao Lei ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Age Groups ◽  
Age Group ◽  
Wuhan City ◽  
Group 3 ◽  
Group 5 ◽  
Group 2 ◽  
Novel Coronavirus ◽  
Reported Data ◽  
Group 1

AbstractBackgroundA novel coronavirus named as “SARS-CoV-2” has spread widely in many countries since December 2019, especially in China. This study aimed to quantify the age-specific transmissibility by using a mathematical model.MethodsAn age-specific susceptible – exposed – symptomatic – asymptomatic – recovered – seafood market (SEIARW) model was developed based on two suspected transmission routes (from market to person and person to person). The susceptible people from Wuhan City were divided into different age groups. We used the subscript i and j to represent age group 1 to 4 (i ≠ j; 1: ≤ 14 years; 2: 15-44 years; 3: 45-64 years; 4: ≥ 65 years) and 1 to 5 (i ≠ j; 1: ≤ 5 years; 2: 6-14 years; 3: 15-24 years; 4: 25-59 years; 4: ≥ 60 years), respectively. Data of reported COVID-19 cases were collected from one published literature from 26 November to 22 December, 2019 in Wuhan City, China. The age-specific transmissibility of the virus was estimated accordingly secondary attack rate (SAR).ResultsThe age-specific SEIARW model fitted with the reported data well by dividing the population into four age groups (χ2 = 4.99 × 10−6, P > 0.999), and five age groups (χ2 = 4.85 × 10−6, P > 0.999). Based on the four-age-group SEIARW model, the highest transmissibility occurred from age group 2 to 3 (SAR23 = 17.56 per 10 million persons), followed by from age group 3 to 2 (SAR32 = 10.17 per 10 million persons). The lowest transmissibility occurred from age group 1 to 2 (SAR12 = 0.002 per 10 million persons). Based on the five-age-group SEIARW model, the highest transmissibility occurred from age group 4 to 5 (SAR45 = 12.40 per 10 million persons), followed by from age group 5 to 4 (SAR54 = 6.61 per 10 million persons). The lowest transmissibility occurred from age group 3 to 4 (SAR34 = 0.0002 per 10 million persons).ConclusionsSARS-CoV-2 has high transmissibility among adults and elder people but low transmissibility among children and young people.

Outcomes in different age groups with primary Ewing sarcoma of the spine: a systematic review of the literature

2019 ◽  
Vol 30 (5) ◽  
pp. 664-673 ◽  
Author(s):  
Garrett K. Berger ◽  
Peyton L. Nisson ◽  
Whitney S. James ◽  
Kristen N. Kaiser ◽  
R. John Hurlbert
Keyword(s):  
Ewing Sarcoma ◽  
Age Groups ◽  
Favorable Outcome ◽  
Adjunctive Treatment ◽  
Age Group ◽  
Surgical Interventions ◽  
Increased Risk ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

OBJECTIVEEwing sarcoma (ES) is among the most prevalent of bone sarcomas in young people. Less often, it presents as a primary lesion of the spine (5%–15% of patients with ES).METHODSA systematic literature search was performed, querying several scientific databases per PRISMA guidelines. Inclusion criteria specified all studies of patients with surgically treated ES located in the spine. Patient age was categorized into three groups: 0–13 years (age group 1), 14–20 years (age group 2), and > 21 (age group 3).RESULTSEighteen studies were included, yielding 28 patients with ES of the spine. Sixty-seven percent of patients experienced a favorable outcome, with laminectomies representing the most common (46%) of surgical interventions. One-, 2-, and 5-year survival rates were 82% (n = 23), 75% (n = 21), and 57% (n = 16), respectively. Patients in age group 2 experienced the greatest mortality rate (75%) compared to age group 1 (9%) and age group 3 (22%). The calculated relative risk score indicated patients in age group 2 were 7.5 times more likely to die than other age groups combined (p = 0.02).CONCLUSIONSPrimary ES of the spine is a rare, debilitating disease in which the role of surgery and its impact on one’s quality of life and independence status has not been well described. This study found the majority of patients experienced a favorable outcome with respect to independence status following surgery and adjunctive treatment. An increased risk of recurrence and death was also present among the adolescent age group (14–20 years).

scholarly journals Functional genioplasty in growing patients

2014 ◽  
Vol 85 (3) ◽  
pp. 360-373 ◽  
Author(s):  
Sylvain Chamberland ◽  
William R. Proffit ◽  
Pier-Eric Chamberland
Keyword(s):  
Orthodontic Treatment ◽  
Age Groups ◽  
Control Group ◽  
Bone Apposition ◽  
Younger Patients ◽  
Mandibular Growth ◽  
Group 3 ◽  
Group 2 ◽  
Inferior Border ◽  
Group 1

ABSTRACT Objective:  To evaluate the role of age as a moderator of bone regeneration patterns and symphysis remodeling after genioplasty. Method:  Fifty-four patients who underwent genioplasty at the end of their orthodontic treatment were divided into three age groups: younger than 15 years at the time of surgery (group 1), 15 to 19 years (group 2), and 20 years or older (group 3). Twenty-three patients who did not accept genioplasty and had a follow-up radiograph 2 years after the end of their orthodontic treatment were used as a control group. Patients were evaluated at three time points: immediate preoperative (T1), immediate postoperative (T2,) and 2 years postsurgery (T3). Results:  The mean genial advancement at surgery was similar for the three age groups, but the extent of remodeling around the repositioned chin was greater in group 1, less in group 2, and still less in group 3. Symphysis thickness increased significantly during the 2-year postsurgery interval for the three groups, and this increase was significantly greater in group 1 than in group 3. Remodeling above and behind the repositioned chin also was greater in the younger patients. This was related to greater vertical growth of the dentoalveolar process in the younger patients. There was no evidence of a deleterious effect on mandibular growth. Conclusion:  The outcomes of forward-upward genioplasty include increased symphysis thickness, bone apposition above B point, and remodeling at the inferior border. When indications for this type of genioplasty are recognized, early surgical correction (before age 15) produces a better outcome in terms of bone remodeling. (Angle Orthod. 2015;85:360–373.)

scholarly journals O sujeito pronominal na fala de Natal/RN: retrato de uma mudança em tempo aparente / The Pronominal Subject in Natal/RN: Portraits of a Change in Apparent Time

2020 ◽  
Vol 25 (2) ◽  
pp. 41
Author(s):  
Marco Antonio Rocha Martins ◽  
Sammy Vieira Carvalho Júnior
Keyword(s):  
Age Groups ◽  
Rio Grande ◽  
Age Group ◽  
Linguistic Change ◽  
Group 4 ◽  
Group 3 ◽  
Theory Of Variation ◽  
Group 2 ◽  
Grammatical Change ◽  
Group 1

Resumo: Seguindo os pressupostos da Teoria da Variação e Mudança linguística, apresentamos neste artigo uma análise de regra variável da expressão do sujeito pronominal em sentenças matrizes na fala de Natal/Rio Grande do Norte/Brasil, com o objetivo de mapear a evolução do preenchimento do sujeito nessa comunidade. Nossa hipótese é de que a fala de Natal evidencia um quadro de mudança gramatical que pode ser observada sob as lentes da mudança em tempo aparente, conforme postulados de Labov (1994). A amostra analisada compõe-se de oito entrevistas realizadas na década de 2010, extraídas do corpus FALA-Natal, com informantes socialmente estratificados. Considerando quatro faixas etárias diferentes dos informantes (Faixa 1 de 8 a 12 anos; Faixa 2 de 15 a 21 anos; Faixa 3 de 25 a 45 anos; e Faixa 4 mais de 50 anos), os resultados mostram que a representação do sujeito pronominal reflete um caso de mudança em tempo aparente, uma vez que construções com sujeitos preenchidos são condicionadas por informantes mais novos, da faixa etária 1, em oposição aos demais informantes das faixas subsequentes.Palavras-chave: preenchimento do sujeito; mudança em tempo aparente; português brasileiro; FALA-Natal.Abstract: In the Theory of Variation and Linguistic Change, we present an analysis of the variable rule of the expression of the pronominal subject in matrix sentences in the speech of Natal/Rio Grande do Norte/Brazil, with the aim of mapping the evolution of the subject’s filling in this community. Our hypothesis is that the speech of Natal shows a grammatical change, which can be observed in light of change in apparent time, as postulated by Labov (1994). The sample analyzed was taken from eight interviews conducted in the decade of 2010, extracted from the FALA-Natal corpus, with socially stratified informants. Considering four different age groups of informants (Group 1 from 8 to 12 years; Group 2 from 15 to 21 years; Group 3 from 25 to 45 years; and Group 4 over 50 years), the results show that the representation of the pronominal subject reflects a case of change in apparent time, since constructions with filled subjects are conditioned by younger informants, in age group 1, as opposed to the other informants in the subsequent groups.Keywords: subject completion; change in apparent time; Brazilian Portuguese; FALA-Natal.

scholarly journals Efficacy of Ceftazidime and Cefepime in the Management of COVID-19 Patients: Single Center Report from Egypt

Antibiotics ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1278
Author(s):  
Ragaey A. Eid ◽  
Marwa O. Elgendy ◽  
Ahmed O. El-Gendy ◽  
Sara O. Elgendy ◽  
Lassaad Belbahri ◽  
...  
Keyword(s):  
Recovery Time ◽  
Age Groups ◽  
Treatment Protocol ◽  
Control Group ◽  
Management Protocol ◽  
Ic50 Values ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

The purpose of this study was to explore the value of using cefepime and ceftazidime in treating patients with COVID-19. A total of 370 (162 males) patients, with RT-PCR-confirmed cases of COVID-19, were included in the study. Out of them, 260 patients were treated with cefepime or ceftazidime, with the addition of steroids to the treatment. Patients were divided into three groups: Group 1: patients treated with cefepime (124 patients); Group 2: patients treated with ceftazidime (136 patients); Group 3 (control group): patients treated according to the WHO guidelines and the Egyptian COVID-19 management protocol (110 patients)/ Each group was classified into three age groups: 18–30, 31–60, and >60 years. The dose of either cefepime or ceftazidime was 1000 mg twice daily for five days. Eight milligrams of dexamethasone were used as the steroidal drug. Careful follow-ups for the patients were carried out. In vitro and in silico Mpro enzyme assays were performed to investigate the antiviral potential of both antibiotics. The mean recovery time for Group 1 was 12 days, for Group 2 was 13 days, and for Group 3 (control) was 19 days. No deaths were recorded, and all patients were recovered without any complications. For Group 1, the recovery time was 10, 12, and 16 days for the age groups 18–30, 30–60, and >60 years, respectively. For Group 2, the recovery time was 11, 13, and 15 days for the age groups 18–30, 30–60, and >60 years, respectively. For Group 3 (control), the recovery time was 15, 16, and 17 days for the age groups 18–30, 30–60, and >60 years, respectively. Both ceftazidime and cefepime showed very good inhibitory activity towards SARS CoV-2′s Mpro, with IC50 values of 1.81 µM and 8.53 µM, respectively. In conclusion, ceftazidime and cefepime are efficient for the management of moderate and severe cases of COVID-19 due to their potential anti-SARS CoV-2 activity and low side effects, and, hence, the currently used complex multidrug treatment protocol can be replaced by the simpler one proposed in this study.

Optimal Propofol Plasma Concentration during Upper Gastrointestinal Endoscopy in Young, Middle-aged, and Elderly Patients

2000 ◽  
Vol 93 (3) ◽  
pp. 662-669 ◽  
Author(s):  
Tomiei Kazama ◽  
Ken Takeuchi ◽  
Kazuyuki Ikeda ◽  
Takehiko Ikeda ◽  
Mutsuhito Kikura ◽  
...  
Keyword(s):  
Plasma Concentrations ◽  
Age Groups ◽  
Young Patients ◽  
Upper Gastrointestinal Endoscopy ◽  
Hemodynamic Responses ◽  
Verbal Command ◽  
Group 3 ◽  
Group 2 ◽  
Somatic Response ◽  
Group 1

Background Suitable propofol plasma concentrations during gastroscopy have not been determined for suppressing somatic and hemodynamic responses in different age groups. Methods Propofol sedation at target plasma concentrations from 0.5 to 4.0 microgram/ml were performed randomly in three groups of patients (23 per group) who were undergoing elective outpatient gastroscopy: ages 17-49 yr (group 1), 50-69 yr (group 2), and 70-89 yr (group 3). Plasma propofol concentration in which 50% of patients do not respond to these different stimuli were determined by logistic regression: verbal command (Cp50ls), somatic response to gastroscopy (Cp50endo), and gag response to gastroscopy (Cp50gag). Hemodynamic responses were also investigated in the different age groups. Results Cp50ls concentrations were 2.23 microgram/ml (group 1), 1.75 microgram/ml (group 2), and 1.40 microgram/ml (group 3). The Cp50endo values in groups 1 and 2 were 2.87 and 2.34 microgram/ml, respectively, which were significantly higher than their respective Cp50ls values. Cp50endo value in group 3 was 1.64 microgram/ml, which was close to its Cp50ls value. Because of a high degree of interpatient variability, Cp50gag could not be defined. Systolic blood pressure response decreased with increasing propofol concentrations. Conclusions The authors determined the propofol concentration necessary for gastroscopy and showed that increasing age reduces it. Propofol concentration that suppresses somatic response induces loss of consciousness in almost all young patients.

Neonatal Neurobehavior in the First 48 Hours of Life: Effect of the Administration of Meperidine With and Without Naloxone in the Mother

PEDIATRICS ◽  
1978 ◽  
Vol 62 (3) ◽  
pp. 294-298 ◽  
Author(s):  
Robert Hodgkinson ◽  
M. Bhatt ◽  
G. Grewal ◽  
G. F. Marx
Keyword(s):  
Age Group ◽  
Naloxone Hydrochloride ◽  
Group 3 ◽  
Group 2 ◽  
Group 1

The early neonatal neurobehavioral scale ‘was administered to three groups of newborns at 2, 4, and 24 hours of age. Group 1 consisted of 28 babies whose mothers had received no narcotics during labor, group 2 of 33 babies whose mothers had received meperidine hydrochloride alone during labor, and group 3 of 40 babies whose mothers had received meperidine followed by 0.4 mg of naloxone hydrochloride intravenously approximately 15 minutes before delivery. Babies who were not exposed to meperidine showed a statistically significantly greater percentage of high scores than those exposed to meperidine alone for all items on the neurobehavioral scale at 2 and 4 hours and for all items except tone and Moro response at 24 hours. Similarly, babies whose mothers had received meperidine and naloxone showed a significantly greater percentage of high scores than those whose mothers had received meperidine alone at 2 hours of age. At 4 hours a difference was found for tone and rooting and at 24 hours for overall score, placing, and total decrement score. It is concluded that naloxone given intravenously to the mother reverses the effect of meperidine on neonatal neurobehavior for approximately two hours after birth. At 4 and 24 hours, however, the neurobehavior of neonates exposed to meperidine and naloxone is depressed almost as much as that of babies exposed to meperidine alone.

Postoperative Morphine Use and Hyperalgesia Are Reduced by Preoperative but Not Intraoperative Epidural Analgesia

2003 ◽  
Vol 98 (6) ◽  
pp. 1449-1460 ◽  
Author(s):  
Joel Katz ◽  
Lorenzo Cohen ◽  
Roger Schmid ◽  
Vincent W.S. Chan ◽  
Adarose Wowk
Keyword(s):  
Morphine Consumption ◽  
Gynecologic Surgery ◽  
Control Group ◽  
Epidural Administration ◽  
Blinded Manner ◽  
Group 3 ◽  
Group 2 ◽  
Double Blinded ◽  
Postoperative Morphine ◽  
Group 1

Background The aim of this study was to evaluate the postoperative morphine-sparing effects and reduction in pain and secondary mechanical hyperalgesia after preincisional or postincisional epidural administration of a local anesthetic and an opioid compared with a sham epidural control. Methods Patients undergoing major gynecologic surgery by laparotomy were randomly assigned to three groups and studied in a double-blinded manner. Group 1 received epidural lidocaine and fentanyl before incision and epidural saline 40 min after incision. Group 2 received epidural saline before incision and epidural lidocaine and fentanyl 40 min after incision. Group 3 received a sham epidural control (with saline injected into a catheter taped to the back) before and 40 min after incision. All patients underwent surgery with general anesthesia. Results One hundred forty-one patients completed the study (group 1, n = 45; group 2, n = 49; group 3, n = 47). Cumulative patient-controlled analgesia morphine consumption at 48 h was significantly lower (P = 0.04) in group 1 (89.8 +/- 43.3 mg) than group 3 (112.5 +/- 71.5 mg) but not group 2 (95.4 +/- 60.2 mg), although the hourly rate of morphine consumption between 24 and 48 h after surgery was significantly lower (P < 0.0009) in group 1 (1.25 +/- 0.02 mg/h) than group 2 (1.41 +/- 0.02 mg/h). Twenty-four hours after surgery, the visual analog scale pain score on movement was significantly less intense (P = 0.005) in group 1 (4.9 +/- 2.2 cm) than group 3 (6.0 +/- 2.6 cm) but not group 2 (5.3 +/- 2.5 cm), and the von Frey pain threshold near the wound was significantly higher (P = 0.03) in group 1 (6.4 +/- 0.6 log mg) than in group 3 (6.1 +/- 0.8 log mg) but not group 2 (6.2 +/- 0.7 log mg). Conclusions Preincisional administration of epidural lidocaine and fentanyl was associated with a significantly lower rate of morphine use, lower cumulative morphine consumption, and reduced hyperalgesia compared with a sham epidural condition. These results highlight the importance of including a standard treatment control group to avoid the problems of interpretation that arise when two-group studies of preemptive analgesia (preincisional vs. postsurgery) fail to find the anticipated effects.

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