PREGNANCY PLANNING. VITAMIN D DEFICIT – INFERTILITY, CORRECTION OF VITAMIN D DEFICIT

Medical Council ◽

10.21518/2079-701x-2017-2-46-47 ◽

2017 ◽

pp. 46-47

Author(s):

O. I. Yazykova ◽

E. G. Khilkevich

Keyword(s):

Vitamin D ◽

Menstrual Cycle ◽

Reproductive Health ◽

Vitamin D Deficiency ◽

Study Objective ◽

Pregnancy Planning ◽

Adequate Level ◽

Foreign Literature ◽

Study Results

Study objective. To study the efficacy of the drugs vitamin D at the stage of planning of pregnancy in women with infertility of various etiologies, according to domestic and foreign literature.Materials and methods. We conducted a search of the literature sources by the keywords “vitamin D”, “infertility”, “pregravid preparation” in domestic and foreign databases: elibrary, Medline/PubMed, Embase, CINAHL. 23 sources were selected.Study results. Vitamin D plays an important role in the regulation of the menstrual cycle and the reproductive health of women. The prevalence of vitamin D deficiency among women with infertility of various etiologies reaches 69%. It is vital to achieve an adequate level of vitamin D in a woman’s body and to prevent its deficiency.Conclusion. For all women with infertility at the stage of preparation it is recommended to conduct assessment of adequacy of vitamin D by determination of 25(OH)D in serum and correction of its deficit to achieve levels of 25(OH)D more than 30 ng/ml.

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Prevalence of vitamin D deficiency in a population-based study: Results from the Heinz Nixdorf Recall Study

Experimental and Clinical Endocrinology & Diabetes ◽

10.1055/s-0033-1336682 ◽

2013 ◽

Vol 121 (03) ◽

Author(s):

H Lahner ◽

S Schramm ◽

KH Jöckel ◽

R Erbel ◽

K Mann ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Population Based ◽

Population Based Study ◽

Heinz Nixdorf Recall Study ◽

Study Results

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Determination of Pregnant women Knowledge toward Risk Factors of Vitamin D Deficiency and Measuring Level During Pregnancy in Al- Nasiriyah City

10.36295/asro.2020.231333 ◽

2020 ◽

Vol 23 (13) ◽

Author(s):

Ali Abdulhakeem Hassan Albakaa ◽

Amer Muhssen Naser ◽

Ali Riyad Saleim

Keyword(s):

Risk Factors ◽

Vitamin D ◽

Pregnant Women ◽

Vitamin D Deficiency

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Levels of vitamin D among overweight and obese adolescents: an observational study

International Journal of Contemporary Pediatrics ◽

10.18203/2349-3291.ijcp20174136 ◽

2017 ◽

Vol 4 (6) ◽

pp. 1934

Author(s):

T. Prashanth Reddy ◽

Kishore Reddy ◽

Madhu Sudhan Reddy ◽

Manjunath G. A.

Keyword(s):

Vitamin D ◽

Observational Study ◽

Vitamin D Deficiency ◽

Overweight And Obesity ◽

Dietary Factors ◽

Vitamin D Status ◽

Obese Adolescents ◽

Vitamin D Levels ◽

Study Results ◽

Wide Range

Background: Normal growth and development requires vitamin D, and its deficiency compromises long term health and increases the risk of chronic disease. Severe vitamin D deficiency include rickets, osteomalacia, osteoporosis, increased risk of fracture, tooth loss. Studies indicate that vitamin D insufficiency (less severe than deficiency) is associated with a wide range of illnesses and chronic conditions, including type 1 diabetes, hypertension, multiple sclerosis and many types of cancer. Currently world is facing an unrecognized and untreated pandemic of vitamin D deficiency. This study aims at showing the relation between Vitamin D status and obesity in adolescent children and to know the dietary factors, life style factors like physical activity contributing to overweight and obesity in adolescents.Methods: Study design: This is an observational study of 30 overweight and obese adolescents based on BMI were studied and their Vitamin D levels were assessed.Results: A total of 14(46.7%) overweight and 16(53.3%) obese adolescents Vitamin D levels were assessed. 20(66.7%) had vitamin D levels <20ng/ml that is in the deficiency range.4(13.3%) had in the insufficiency range (21-30ng/ml), 6(20%) had in the sufficient range. Results shows vitamin D levels were significantly less in obese and overweight adolescents.Conclusions: Study results confirm that Vitamin D deficiency or insufficiency is common to obese and overweight adolescents, this may help to explain the relationship between obesity and several chronic diseases that are associated with poor Vitamin D status.

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Vitamin D deficiency in men as the cause of infertile marriages: pilot study results

Relevant endocrinology ◽

10.18508/endo3753 ◽

2015 ◽

Author(s):

Nanulya Kupreishvili

Keyword(s):

Vitamin D ◽

Pilot Study ◽

Vitamin D Deficiency ◽

Study Results

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Vitamin D Deficiency in Children with Chronic Renal Disease

Open Access Macedonian Journal of Medical Sciences ◽

10.3889/oamjms.2021.6991 ◽

2021 ◽

Vol 9 (B) ◽

pp. 1751-1757

Author(s):

S. B. Dyussenova ◽

M. Y. Gordiyenko ◽

G. B. Serikova ◽

S. A. Turlybekova ◽

A. A. Issayeva ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Bone Growth ◽

Chronic Renal Disease ◽

Immune Disorders ◽

Increased Risk ◽

The Relationship ◽

Increased Susceptibility

BACKGROUND: Vitamin D is essential for children and adults for healthy bone growth. Lack of this vitamin in children can cause rickets, and in adults, softening of the bones and an increased risk of fractures. Vitamin D deficiency can cause immune disorders, increased susceptibility to infections, the development of certain types of cancer, diabetes mellitus, and cardiovascular diseases. AIM: The article presents the literature data and the results of our own research on the analysis of the relationship between chronic kidney disease (CKD) and Vitamin D provision in children from 1 to 17 years old. The aim of the study was to establish the level of Vitamin D in children with different stages of CKD. METHODS: Between January 2020 and September 2020, we examined 40 children (16 boys and 24 girls). The patients’ age ranged from 1 to 17 years inclusive. RESULTS: Vitamin D deficiency was found in 62.5% of children with CKD. Vitamin D deficiency was noted in 25% of cases. The prevalence of Vitamin D deficiency correlates with a decrease in glomerular filtration rate. CONCLUSION: Determination of Vitamin D level in children with CKD is important for timely correction and prevention of further progression of CKD. Timely substitution therapy will improve the quality of life of a child with CKD and prevent the development of complications.

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Geographic and Seasonal Variation of Vitamin D: A Retrospective Study in Two Centers of Nepal

Journal of Nepal Health Research Council ◽

10.33314/jnhrc.v18i1.1873 ◽

2020 ◽

Vol 18 (1) ◽

pp. 103-107

Author(s):

Arun Sedhain ◽

Gandhi R Bhattarai ◽

Sanjaya Raya Yadav ◽

Bhupendra Raj Pandey ◽

Thakur Prasad Pant

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Winter Season ◽

Hypovitaminosis D ◽

Cross Sectional Study ◽

Reproductive Age ◽

Age Group ◽

Cross Sectional ◽

Study Results ◽

The Status

Background: Vitamin D deficiency is a common problem in many countries throughout the world. This study aimed at understanding the status of vitamin D deficiency in relation to age, gender, geography and season among relatively bigger numbers of population residing in central and western regions of Nepal.Methods: This retrospective cross-sectional study was carried out by reviewing the records of vitamin D tests in two centers of Nepal- namely united reference laboratories at Pokhara and Chitwan Medical College at Chitwan. A total of 3320 individuals who were tested for clinical suspicion of vitamin D deficiency over a period of one year were included in the study. Results: Mean vitamin D level was 18.7 ng/mL. Majority of subjects tested for vitamin D were females (71.36 %) with female to male ratio of 2.49:1. Hypovitaminosis D (? 30 ng/mL) was found in 84.5% subjects and was moderate to severely deficit (<10 ng/mL) in 25.9% of subjects. Status of hypovitaminosis D was found to be less in ?50 years (79.9%) than the younger subjects (89.9% in ?18 years and 87.0% in 19-49 years age group). Vitamin D deficiency was found lower in hills districts (80.8% vs 89.7% in the plains), which was found to be more pronounced during winter through summer seasons as compared to fall season.Conclusions: Population residing in plain areas and summer, spring and winter season are found to have increased problem of Hypovitaminosis D. It is also found to be common among younger children and female of reproductive age group. We have also found out the increased problem of hypovitaminosis D among population residing in the plain areas than in the hills especially in the summer, spring and winter season.Keywords: Geographic variation; hypovitaminosis D; Nepal

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25-Hydroxyvitamin D and matrix metalloproteinases-2, -9 level in patients with primary open angle glaucoma and pseudoexfoliative glaucoma/syndrome

Ophthalmology journal ◽

10.17816/ov10110-16 ◽

2017 ◽

Vol 10 (1) ◽

pp. 10-16

Author(s):

Inessa S Beletskaya ◽

Tatiana L Karonova ◽

Sergey Yu Astakhov

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Study Groups ◽

Control Group ◽

Open Angle ◽

Hydroxyvitamin D ◽

Study Results ◽

Clinically Significant

Aim. To determine serum 25(OH)D and plasma MMP-2 and MMP-9 levels in patients with primary open-angle glaucoma (POAG), pseudoexfoliation glaucoma (PEG), and pseudoexfoliation syndrome (PES) - to assess potential associations between vitamin D status and these diseases. Methods. We included 238 patients (105 males and 133 females) aged from 55 to 75 years. One hundred twenty two patients had PEG, 46 patients had POAG, 32 had PES. 38 subjects were healthy, and were considered as the control group. Cases with clinically significant systemic diseases and concomiatant eye diseases were excluded, if there was a confirmed pathogenic impact of vitamin D and MMP. The serum 25(OH)D level was investigated by immunochemiluminescence method, plasma MMP-2 and MMP-9 levels - by ELISA. Results. Serum 25(OH)D level was between 4.6 and 82.25 nM/l (mean 41.7 nM/l), so most participants showed vitamin D deficiency. It was shown that mean serum 25(OH)D level in patients with PEG, POAG and PES was similar (39.3 ± 1.2, 38.8 ± 2.1 and 40.51 ± 2.4 nM/l, p > 0.05), but it was lower than that in the control group (52.7 ± 2.1 nM/l, p < 0.01). Plasma MMP-2 concentration was the same in all study groups. Plasma MMP-9 level was higher in POAG and PES patients (48.23 ± 3.26 and 54.01 ± 3.57 ng/ml) than in the control group (32.60 ± 2.34 ng/ml, p < 0.001) and PEG patients (40.86 ± 3.60 ng/ml, p < 0.05). We found positive correlations between MMP-2 and MMP-9 levels in patients with PEG (r = 0.48, p = 0.001) and patients with POAG (r = 0.43, p = 0.003). The correlation analysis showed also a negative relation between 25(OH)D and MMP-9 (r = -0.32, p = 0.02), MMP-2 (r = -0.33, p = 0.02) in patients with POAG. Summary. Study results confirmed a potential role of vitamin D in apoptosis regulation and tissue remodeling in patients with POAG and PES. Hence, vitamin D deficiency can be considered as a risk factor for glaucoma development.

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Vitamin D Intake in Slovenian Adolescents, Adults, and the Elderly Population

Nutrients ◽

10.3390/nu13103528 ◽

2021 ◽

Vol 13 (10) ◽

pp. 3528

Author(s):

Maša Hribar ◽

Hristo Hristov ◽

Živa Lavriša ◽

Barbara Koroušić Seljak ◽

Matej Gregorič ◽

...

Keyword(s):

Vitamin D ◽

Vitamin D Deficiency ◽

The Elderly ◽

Dietary Vitamin ◽

Food Groups ◽

Cross Sectional ◽

Vitamin D Intake ◽

Study Results ◽

Using Data ◽

Dietary Vitamin D

Vitamin D is involved in calcium and phosphorus metabolism, and is vital for numerous bodily functions. In the absence of sufficient UV-B light-induced skin biosynthesis, dietary intake becomes the most important source of vitamin D. In the absence of biosynthesis, the recommended dietary vitamin D intake is 10–20 µg/day. Major contributors to dietary vitamin D intake are the few foods naturally containing vitamin D (i.e., fish), enriched foods, and supplements. The present study aimed to estimate the vitamin D intake in Slovenia, to identify food groups that notably contribute to vitamin D intake, and to predict the effects of hypothetical mandatory milk fortification. This study was conducted using data collected by the national cross-sectional food consumption survey (SI.Menu) in adolescents (n = 468; 10–17 years), adults (n = 364; 18–64 years), and the elderly (n = 416; 65–74 years). Data collection was carried out between March 2017 and April 2018 using the EU Menu Methodology, which included two 24-hour recalls, and a food propensity questionnaire. Very low vitamin D intakes were found; many did not even meet the threshold for very low vitamin D intake (2.5 µg/day). Mean daily vitamin D intake was 2.7, 2.9, and 2.5 µg in adolescents, adults, and the elderly, respectively. Daily energy intake was found to be a significant predictor of vitamin D intake in all population groups. In adolescents and adults, sex was also found to be a significant predictor, with higher vitamin D intake in males. The study results explained the previously reported high prevalence of vitamin D deficiency in Slovenia. An efficient policy approach is required to address the risk of vitamin D deficiency, particularly in vulnerable populations.

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