scholarly journals Impact of dietary supplementation of vitamin E (alpha-tocopherol acetate) on genetic expression of inflammatory cytokines and growth efficiency of broiler chickens

2021 ◽  
Vol 40 (2) ◽  
pp. 202-206
Author(s):  
aya Elshawash ◽  
Fatma Elgendy ◽  
Olla Khalifa ◽  
Shabaan Hemeda
Keyword(s):  
Vitamin E ◽  
Inflammatory Cytokines ◽  
Broiler Chickens ◽  
Dietary Supplementation ◽  
Growth Efficiency ◽  
Alpha Tocopherol ◽  
Genetic Expression ◽  
Tocopherol Acetate

Plasma, liver and fat alpha-tocopherol concentrations in sheep given various oral and subcutaneous doses of vitamin E

1991 ◽  
Vol 31 (1) ◽  
pp. 45 ◽  
Author(s):  
GJ Judson ◽  
PJ Babidge ◽  
WJ Babidge
Keyword(s):  
Adipose Tissue ◽  
Vitamin E ◽  
Plasma Lipid ◽  
Alpha Tocopherol ◽  
Oral Dosage ◽  
Subcutaneous Injections ◽  
Treatment Groups ◽  
Tocopherol Acetate ◽  
Pelleted Diet ◽  
Oral Doses

Alpha-tocopherol concentrations were measured in plasma, liver and adipose tissue of young sheep given dl-alpha-tocopherol acetate, orally or subcutaneously, at dosages of 0, 15, 30, 60 or 120 mg/kg liveweight while the sheep consumed a pelleted diet containing less than 10 mg/kg dry matter alpha-tocopherol. Significant responses in plasma alpha-tocopherol concentrations were observed after 1 and 4 days in sheep given oral doses of the vitamin but not in those given subcutaneous injections. Variation between animals within treatment groups was not reduced by expressing plasma alpha-tocopherol as a ratio of various plasma lipid fractions. Oral doses of 30 and 120 mg/kg liveweight of alpha-tocopherol increased the mean liver alpha-tocopherol concentrations at 7 days, but only the highest dose significantly increased liver concentrations above that of untreated sheep at 1 and 2 months. Increases in mean liver alpha-tocopherol concentrations were observed 1 month after subcutaneous injections, at dosages above 15 mg/kg liveweight, suggesting a slow mobilisation of the vitamin from the injection site. Concentrations of alpha-tocopherol in adipose tissue were not altered by alpha-tocopherol treatment. Plasma and liver alpha-tocopherol concentrations were positively correlated, although vitamin E treatments and time from treatment had small but significant effects on this relationship. The results suggest that oral dosage is preferable to subcutaneous injection when administering alpha-tocopherol acetate to sheep. An oral dose of 120 mg/kg liveweight will probably maintain adequate liver alpha-tocopherol concentrations for a period of about 2 months in sheep consuming diets of low vitamin E content.

scholarly journals Egg production, egg quality, and lipid peroxidation status in laying hens maintained at a low ambient temperature (6°C) and fed a vitamin C and vitamin E-supplemented diet

2012 ◽  
Vol 48 (No. 1 - 2) ◽  
pp. 33-40 ◽  
Author(s):  
O. Kucuk ◽  
N. Sahin ◽  
K. Sahin ◽  
Gursu MF ◽  
F. Gulcu ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Vitamin E ◽  
Vitamin C ◽  
Egg Production ◽  
Laying Hens ◽  
Egg Quality ◽  
Basal Diet ◽  
Alpha Tocopherol ◽  
Tocopherol Acetate ◽  
Egg Shell

This experiment was conducted to evaluate the effects of vitamin C (L-ascorbic acid) and vitamin E (α-tocopherol acetate) on egg production, egg quality, lipid peroxidation status (measured as MDA), and some serum metabolites in laying hens (Hy-Line) maintained at a low ambient temperature (6°C). One hundred and twenty laying hens (18-wk-old) were divided into four groups, 30 hens per group. The laying hens were fed either a basal diet or the basal diet supplemented with either 250 mg of L-ascorbic acid/kg of diet, 250 mg of α-tocopherol acetate/kg of diet or 250 mg of L-ascorbic acid plus 250 mg of α-tocopherol acetate/kg of diet. Although feed consumption of the hens was similar (P > 0.05) among treatments, supplemental vitamin C and E significantly increased final body weight, egg production, and improved feed efficiency (P < 0.05). Egg weights were also greater (P < 0.05) in hens supplemented with the combination of vitamin C and E than that of hens supplemented either vitamin or no vitamin (control). Haugh unit did not change upon each vitamin supplementation, but the combination of the vitamin supplement yielded a higher Haugh unit (P < 0.05). Each dietary supplement of vitamin C and vitamin E improved the egg quality (P < 0.05) resulting in a greater specific gravity, thicker egg shell, and heavier egg shell weight. Separately or as a combination, supplemental vitamin C and E decreased MDA, glucose, cholesterol, and triglyceride concentrations (P < 0.05). Results of the present study showed that supplementing vitamin C and vitamin E, particularly as a combination, improved the performance of cold-stressed laying hens, offering a potential protective management practice in preventing cold stress-related losses in performance of laying hens. Results of the present study also indicated that the effects of vitamin C and vitamin E are additive.

scholarly journals The effect of polyphenols and vitamin E on the antioxidant status and meat quality of broiler chickens fed low-quality oil

2019 ◽  
Vol 62 (1) ◽  
pp. 287-296 ◽  
Author(s):  
Magdalena Mazur-Kuśnirek ◽  
Zofia Antoszkiewicz ◽  
Krzysztof Lipiński ◽  
Joanna Kaliniewicz ◽  
Sylwia Kotlarczyk
Keyword(s):  
Fatty Acids ◽  
Vitamin E ◽  
Meat Quality ◽  
Broiler Chickens ◽  
Antioxidant Status ◽  
Dietary Supplementation ◽  
Negative Control ◽  
Enzymatic Antioxidants ◽  
Group I

Abstract. The aim of this study was to determine the effect of vitamin E and polyphenols on the antioxidant potential and meat quality of broiler chickens fed diets supplemented with low-quality oil. The experimental materials comprised 120 male Ross 308 broilers (six treatments, 10 replications, two birds per replication). Dietary supplementation with vitamin E and/or polyphenols was applied in the following experimental design: group I (negative control) – without supplementation without low-quality oil; group II (positive control) – without supplementation + low-quality oil; group III – supplementation with 100 mg kg−1 of vitamin E+ low-quality oil; group IV – 200 mg kg−1 of vitamin E + low-quality oil; group V – 100 mg kg−1 of vitamin E and 100 mg kg−1 of polyphenols + low-quality oil; group VI – 200 mg kg−1 of polyphenols + low-quality oil. Rapeseed oil oxidised under laboratory conditions was added to the diets of broiler chickens from groups II to VI. The applied antioxidants had no effect on the growth performance of chickens fed oxidised oil. Increased dietary inclusion levels of vitamin E and/or polyphenols improved the antioxidant status in the blood and increased the content of non-enzymatic antioxidants in the liver and breast muscles of broilers fed low-quality oil. The tested antioxidants had no influence on carcass quality parameters in chickens fed oxidised oil. However, birds fed diets with the addition of vitamin E were characterised by a higher gizzard weight and higher pH of gizzard digesta. Dietary supplementation with vitamin E and polyphenols or polyphenols alone contributed to a lighter colour and lower pH of breast muscles and an increase in the content of fat and ash in the breast muscles of broilers fed oxidised oil. The breast muscles of birds given 100 or 200 mg kg−1 of supplemental vitamin E were characterised by higher concentrations of n-6 polyunsaturated fatty acids (PUFAs) and hypocholesterolemic fatty acids (DFAs), a more desirable DFA∕OFA ratio, and a lower atherogenicity index (AI). Polyphenols combined with vitamin E can be a valuable component of diets for broiler chickens when the problem of low-quality oil occurs.

scholarly journals Interventions Preventing Vaginitis, Vaginal Atrophy after Brachytherapy or Radiotherapy Due to Malignant Tumors of the Female Reproductive Organs—A Systematic Review

2021 ◽  
Vol 18 (8) ◽  
pp. 3932
Author(s):  
Adrianna Wierzbicka ◽  
Dorota Mańkowska-Wierzbicka ◽  
Stanisław Cieślewicz ◽  
Marta Stelmach-Mardas ◽  
Marcin Mardas
Keyword(s):  
Vitamin E ◽  
Side Effects ◽  
Vitamin A ◽  
Late Onset ◽  
Malignant Tumors ◽  
Alpha Tocopherol ◽  
Mucosal Inflammation ◽  
Vaginal Atrophy ◽  
Vaginal Dryness ◽  
Tocopherol Acetate

Background: Radiotherapy, as a method of treatment of cervical and uterine cancers, may induce severe late-onset vaginal side effects. Unfortunately, little evidence on the management of adverse effects has been presented. This study aimed to evaluate the available interventions which reduce symptoms of vaginitis and vaginal atrophy by improving dyspareunia, mucosal inflammation, vaginal pH and vaginal dryness in women who have undergone brachytherapy or radiotherapy due to uterine or cervical malignancies. Materials and methods: A comprehensive literature search was performed following PRISMA guidelines. The systematic search was conducted using electronic databases, namely Scopus, Web of Science and PubMed, between October and November 2020 to identify randomized controlled trials (RCT) and, prospective randomized studies (PRS). Results: The analyzed population consists of 376 patients with uterine or cervical cancer, treated with hyaluronic acid, vitamin A, vitamin E, alpha-tocopherol acetate and dienestrol. Intervention with HA along with vitamin A and vitamin E revealed advantage in endpoints such as reduced dyspareunia, vaginal mucosal inflammation, vaginal dryness, bleeding, fibrosis and cellular atypia. Administration of alpha-tocopherol acetate reduced vaginal mucosal inflammation and improved vaginal acanthosis, whereas dienestrol resulted in reduced dyspareunia, vaginal caliber and bleeding. Conclusions: Vaginal suppositories were found to be clinically effective at the management of late-onset vulvovaginal side effects after radiotherapy.

USE OF d-1, ALPHA-TOCOPHEROL ACETATE (SYNTHETIC VITAMIN E)

1942 ◽  
Vol 96 (3) ◽  
pp. 286-295 ◽  
Author(s):  
Gabriel A. Schwarz ◽  
George D. Gammon ◽  
Richard L. Masland
Keyword(s):  
Vitamin E ◽  
Alpha Tocopherol ◽  
Synthetic Vitamin ◽  
Tocopherol Acetate

Effects of feeding Isomaltooligosaccharides on the growth performance, carcass traits and immune response of broiler chickens

2014 ◽  
Vol 3 (1) ◽  
pp. 150-157
Author(s):  
Khalid M. Gaafar
Keyword(s):  
Immune Response ◽  
Growth Performance ◽  
Broiler Chickens ◽  
Carcass Traits ◽  
Dietary Supplementation ◽  
Control Group ◽  
Broiler Chicks ◽  
Feed Conversion ◽  
Flu Vaccine ◽  
Lipids Profile

The research was conducted to study the effect of feeding broiler chickens on diets containing isomaltooligosaccharides on the growth performance, carcass traits and immune response. 90-one day old broiler chicks were used according to completely randomized two treatment groups and one control, 30 birds each. Birds fed ad-libitum on basal starter and grower-finisher diets for 35 day. Diets of treatment`s groups contained 0.5 g/Kg and 1 g/Kg of Isomaltooligosaccharides, while the control group fed on the basal diets without Isomaltooligosaccharides supplementation. Dietary supplementation of broiler chickens with Isomaltooligosaccharides improved body weight, feed conversion, carcass traits, two lymphoid organs weight and log antibody titer against avian flu vaccine. Most of the highest values were for birds fed low levels of Isomaltooligosaccharides. Feed intake decreases as Isomaltooligosaccharides level increases. Dietary supplementation with Isomaltooligosaccharides did not affect the lipids profile (triglycerides, total cholesterol, LDL and HDL), however the blood VLDL levels decreased with increased levels of Malondialdehyde and Glutathione reductase. Collectively, Dietary supplementation of broiler chickens with 0.5 g/Kg diet of Isomaltooligosaccharides improved growth performance, carcass traits and immune status.

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