scholarly journals Lymphoplasmacytic hemorrhagic cystitis in dog: case report

2021 ◽  
Vol 15 (1) ◽  
pp. 9-14
Author(s):  
Karen Santos Março ◽  
João José da Costa Neto ◽  
Suzana Akemi Tsuruta ◽  
Alisson de Souza Costa ◽  
Sofia Borin-Crivellenti ◽  
...  

Hematuria is a relatively common manifestation in dogs and cats secondary to disorders of the urinary tract, such as bacterial cystitis and urolithiasis, with its treatment being limited to the elimination of the primary cause. However, when hematuria is persistent or capable of causing significant hematological disorders, other less common causes should be investigated. A dog, pit bull, male, 12 years old, was admitted in the Hospital Veterinário da Universidade de Uberlândia (Veterinary Hospital of the Federal University of Uberlândia) with a major complaint of severe urinary bleeding 10 days ago. Laboratory tests showed normocytic and normochromic anemia, associated to intense hematuria. Ultrasound images revealed alterations compatible with chronic cystitis. Based on the results of the laboratory and imaging tests, treatments with antibiotic therapy associated to blood transfusions were started and the animal was referred for bladder biopsy. The histopathologic examination revealed lymphoplasmacytic hemorrhagic cystitis, a rare and very aggressive disease, which presents similar descriptions in human beings, but not yet described in dogs.

2017 ◽  
Vol 07 (02) ◽  
pp. e138-e143 ◽  
Author(s):  
Florencia Angkasa ◽  
Leila Mohammadi ◽  
Deepa Taranath ◽  
Ajay Taranath ◽  
Marcus Brecht

Proptosis in the neonatal period is relatively infrequent and has diverse underlying etiologies. One of the more common causes appears to be orbital subperiosteal hematoma. Early detection, differentiation from other causes, and regular follow-up are essential as loss of vision can occur. We describe two cases of neonatal proptosis caused by orbital subperiosteal hematoma highlighting different diagnostic and management approaches, and provide a summary of previously reported cases. Spontaneous resolution occurs in most cases; however, emergent surgical evacuation is warranted in cases of optic nerve compression. This is the first report to provide orbital ultrasound images of uncomplicated neonatal orbital subperiosteal hematoma. Orbital ultrasound followed by magnetic resonance imaging (MRI) is a valid nonradiation approach for assessing neonatal proptosis due to subperiosteal orbital hematoma.


2020 ◽  
Vol 7 (2) ◽  
pp. 41-48
Author(s):  
Haitham N. AL-Koubaisy

Chronic renal failure is fatal disease because it leads to failure of excretory ,metabolic and endocrine functions of the kidneys which lead to disturb all physiological functions of the body some of these derangements is fatal to human beings to save human these body disturbances by chronic renal failure is treated by renal transplant and dialysis in different ways including peritoneal dialysis (PD.). Chronic renal failure is a common disease in patients attending Ramadi teaching hospital whom treated by peritoneal dialysis (PD) with variable results . So this study is introduced to detect the health status for managing chronic renal failure treated by peritoneal dialysis. All patients were 100 patients (53 male and 47 female) with CRF who admitted to the medical word in Al-Ramadi teaching hospital during a period from November 2008 till July 2009. Thorough history, examination and investigations were done for them including: hemoglobin, ESR ,blood urea, serum creatinine, ECG and abdominal U/S then PD was done for them according to their indications. The study showed that male was 53% with the age between 13 and 87 years while the female was 47% with the age between 12 and 91 years. Diabetes mellitus (DM) and hypertension (HT) were the most common cause of CRF. The outcome was: 30%complete improvement, 21% partial improvement, 26% less responsive and 23% died. In the last months of my study there was significant improvement. Inconclusion; DM and HT were the most common causes of CRF respectively; however obstructive uropathy had a notable ratio. There was no significant difference regarding sex. The outcome of PD was poor early in my study with significant improvements later.


2021 ◽  
Vol 51 (4) ◽  
Author(s):  
Lara Cassaro ◽  
Neylla Zopelari de Almeida ◽  
Virgilio Zoppi Lemos ◽  
Jéssica Miranda Cota ◽  
Luiz Alexandre Moscon ◽  
...  

ABSTRACT: Myelolipoma is a benign neoplasm composed of mature adipocytes and hematopoietic elements. This tumor is rare in dogs and cats and can develop in several organs and tissues. This report describes a case of splenic myelolipoma in a dog characterizing its clinical-pathological and ultrasonography aspects. A 9-year-old, female, mixed-breed, castrated dog was referred to the veterinary hospital with increased abdominal circumference. Ultrasonography revealed splenomegaly with masses of not measurable dimensions along the entire length of the parenchyma. The spleen was removed, and a fragment was sent for histopathological analysis. Macroscopically, the spleen was enlarged, with irregularly nodular growths that project above the surface of the organ. Nodules were red with small yellow areas. Microscopically, the spleen was effaced by a well-demarcated and not encapsulated mass composed of histologically well-differentiated neoplastic adipose tissue with islands and nests of varying proportions of hematopoietic elements. Histological examination confirmed the diagnosis of myelolipoma. Myelolipomas are observed on ultrasound images as hyperechoic masses or nodules with homogeneous echo texture. Here, ultrasound appearance involved mixed echogenicity and heterogeneous echotexture, due to the mixture of fat and non-fatty material components of the tumor.


Author(s):  
Chau Duc Nguyen Huu

Objectives: To identify the pattern and etiology of diseases in children presented hepatomegaly at Pediatrics Department in Hue Central Hospital, Vietnam. Material and Methods: The Present study was conducted to evaluate the possible etiology and clinical features of children presented with hepatomegaly. A total of 107 children, from one month to fifteen years of age with hepatomegaly admitted in the Pediatric Department of Hue Central Hospital, Vietnam from May 2018 to April 2019 were included in this study. Results: The most common causes of hepatomegaly were inflammation/infection of the liver (miscellaneous cause included), hematological diseases and congestion heart failure with the percentage of 50.5%; 27,1% and 12,1%; respectively. Among the hepatitis group, viral agents account for nearly 50.0%, of which the most common one was Cytomegalovirus accounting for nearly 30.0%. Distribution of causes by age group revealed most cases in 1 year-old or younger children was caused by inflammation (53.8%), and in the older than 1 year-old children were hematological disorders (47.3%) which has statistical significance (P<0.05). Conclusions: Our research observed that the most common causes of the group of ≤ 1 year old were hepatitis, followed by cardiovascular disease and biliary obstruction due to congenital biliary atresia, and in the older than 1 year group, hematological disorders was the most common.


2012 ◽  
Vol 45 (3) ◽  
pp. 365-368 ◽  
Author(s):  
Helio Langoni ◽  
Guilherme Matteucci ◽  
Bruno Medici ◽  
Lucilene Granuzio Camossi ◽  
Virgínia Bodelão Richini-Pereira ◽  
...  

INTRODUCTION: Toxoplasma gondii and Neospora caninum are related Apicomplexa parasites responsible for systemic diseases in many species of animals, including dogs. METHODS: This study aimed to determine the occurrence of T. gondii and N. caninum infections in 50 dogs with neurological signs that were admitted to the Veterinary Hospital of Universidade Estadual Paulista, City of Botucatu, Brazil. All animals were screened for antibodies using an immunofluorescent antibody test for both parasites. Tissues of positive animals were bioassayed in mice (T. gondii) and gerbils (N. caninum), and DNA was analyzed using the polymerase chain reaction (PCR). Positive samples for T. gondii by PCR were typed using restriction fragment length polymorphism-PCR for 11 markers: SAG1, SAG2 (5′-3′-SAG2 and alt.SAG2), SAG3, Btub, GRA6, L358, c22-8, c29-6, PK1 and Apico, and CS3 marker for virulence analysis. RESULTS: Specific antibodies were detected in 11/50 (22%; 95% confidence interval (CI95%), 12.8-35.3%) animals for T. gondii and 7/50 (14%; CI95%, 7.02-26.3%) for N. caninum. In the bioassay and PCR, 7/11 (63.6%; CI95%, 34.9-84.8%) samples were positive for T. gondii and 3/7 (42.9%; CI95%I, 15.7-75.5%) samples were positive for N. caninum. Three different genotypes were identified, but only 1 was unique. CONCLUSIONS: These data confirm the presence of T. gondii and N. caninum in dogs from Brazil, indicating the importance of this host as a sentinel of T. gondii for human beings, and the genotypic variation of this parasite in Brazil.


Ulcers ◽  
2013 ◽  
Vol 2013 ◽  
pp. 1-9 ◽  
Author(s):  
Shubhangi Vinayak Agale

Chronic leg ulcer is defined as a defect in the skin below the level of knee persisting for more than six weeks and shows no tendency to heal after three or more months. Chronic ulceration of the lower legs is a relatively common condition amongst adults, one that causes pain and social distress. The condition affects 1% of the adult population and 3.6% of people older than 65 years. Leg ulcers are debilitating and greatly reduce patients' quality of life. The common causes are venous disease, arterial disease, and neuropathy. Less common causes are metabolic disorders, hematological disorders, and infective diseases. As many factors lead to chronic lower leg ulceration, an interdisciplinary approach to the systematic assessment of the patient is required, in order to ascertain the pathogenesis, definitive diagnosis, and optimal treatment. A correct diagnosis is essential to avoid inappropriate treatment that may cause deterioration of the wound, delay wound healing, or harm the patient. The researchers are inventing newer modalities of treatments for patients with chronic leg ulceration, so that they can have better quality life and reduction in personal financial burden.


Blood ◽  
2006 ◽  
Vol 108 (11) ◽  
pp. 4934-4934
Author(s):  
Varda Deutsch ◽  
Yair Herishanu ◽  
Aaron Polliack ◽  
Elizabeth Naparstek ◽  
Dina Meyuhas ◽  
...  

Abstract B-CLL, the most common type of leukemia in adults, is heterogeneous with a varying clinical course ranging from indolent to aggressive disease. CLL patients with mutated Ig V(H) genes have a good prognosis while those with non-mutated Ig V(H) status and expression of the ZAP70 protein tyrosine kinase generally have aggressive disease and shorter survival. Testing for IgV(H) mutations is not routinely performed due to cost and ZAP70 testing is still technically difficult. As these tests remain generally inappropriate for B-CLL patient screening, we tested the capacity of the new Beckmann Coulter LH750 blood analyzers to provide additional morphometric information on the CLL cell population. These analyzers use a highly informative positional parameter technology - VCS (Volume, Conductivity, Scatter) technology, and automated RPD analysis which provide the Mean and Standard Deviation of Volume, Conductivity and Scatter (VCS) for each of the main WBC types (neutrophils, lymphocytes, monocytes and eosinophils), thereby enabling the detection of abnormal WBC populations associated with various hematological and non-hematological disorders. We attempted to determine if the RPD generated could differentiate between the ZAP70pos and ZAP70neg B-CLL subgroups as determined by high resolution quantitative ZAP70 flow cytometry analysis (1). This study included 30 newly diagnosed untreated CLL patients. CBC was performed on all samples using automated leukocyte differentials in the Beckmann-Coulter LH750. Statistical analysis was performed with Medcalc® 8.1.1.0. Results show that there was no correlation between the WBC number, ZAP70pos expression (found in 59% of the cases) and lymphocyte volume, scatter, or conductivity or SD of these parameters. However, differences in the automated morphology of the Zap70neg compared with Zap70pos CLL lymphocytes was detected. When compared to normal lymphocyte volume (85.8±14.5), the Lymphocyte Mean Volume (MLYV) was lower in the ZAP70neg samples (77.7±17.6) (p&lt;0.05), while the ZAP70pos samples had increased volumes (87.5±15.8), similar to values reported in other myeloproliferative states. The conductivity of the ZAP70neg cells was reduced (110±15.0) below normal (117±11.5) (p=0.038), while the ZAP70pos cells had conductivity similar to the control group. Higher levels of lymphocyte apoptosis were clearly observed in the ZAP70neg samples by VCS. When using ROC (receiver operating curve analysis) to detect the potential ZAP70neg cases, the cut off proposed is MLYV &lt; 76 with a sensitivity of 69.2% and a specificity of 70% AUC 0,650. Herein we propose an entirely new approach which may provide a novel diagnostic screening approach to enable identification of CLL patients who do not require further complex testing. This data is derived directly from the CBC of the Beckman-Coulter LH750 analyzers at no extra cost. As it will be necessary to analyze many more cases from different laboratories, an international working group has been formed in an attempt to confirm these early observations.


1998 ◽  
Vol 15 (2) ◽  
pp. 65-72 ◽  
Author(s):  
Margherita Gracis ◽  
Paul Orsini

In dogs and cats, the most common causes of dental injury are fights with other animals, car accidents, falls from a height, and chewing on hard materials such as bones or rocks. The trauma more often causes fracture of the teeth, but sometimes avulsion or luxation can occur. Avulsion is the complete displacement of the tooth out of the alveolar socket and luxation is the partial displacement of the tooth. Tooth luxation and avulsion represent dental emergencies. Time is an important factor for successful treatment; the prognosis becomes poorer the longer the tooth is out of the socket. This paper describes the guidelines for treatment of dental displacement in cats and dogs and presents six cases of dental lateral luxation in dogs seen at the Veterinary Hospital of the University of Pennsylvania (VHUP) in the period from May 1996 to September 1997.


2020 ◽  
Vol 7 (2) ◽  
pp. 41-48
Author(s):  
Haitham N. AL-Koubaisy ◽  
Khalid A. AL-Rawi ◽  
Bahget Sweedan

Chronic renal failure is fatal disease because it leads to failure of excretory ,metabolic and endocrine functions of the kidneys which lead to disturb all physiological functions of the body some of these derangements is fatal to human beings to save human these body disturbances by chronic renal failure is treated by renal transplant and dialysis in different ways including peritoneal dialysis (PD.). Chronic renal failure is a common disease in patients attending Ramadi teaching hospital whom treated by peritoneal dialysis (PD) with variable results . So this study is introduced to detect the health status for managing chronic renal failure treated by peritoneal dialysis. All patients were 100 patients (53 male and 47 female) with CRF who admitted to the medical word in Al-Ramadi teaching hospital during a period from November 2008 till July 2009. Thorough history, examination and investigations were done for them including: hemoglobin, ESR ,blood urea, serum creatinine, ECG and abdominal U/S then PD was done for them according to their indications. The study showed that male was 53% with the age between 13 and 87 years while the female was 47% with the age between 12 and 91 years. Diabetes mellitus (DM) and hypertension (HT) were the most common cause of CRF. The outcome was: 30%complete improvement, 21% partial improvement, 26% less responsive and 23% died. In the last months of my study there was significant improvement. Inconclusion; DM and HT were the most common causes of CRF respectively; however obstructive uropathy had a notable ratio. There was no significant difference regarding sex. The outcome of PD was poor early in my study with significant improvements later.


2005 ◽  
Vol 10 (1) ◽  
Author(s):  
C.A.L. GODOY-ESTEVES ◽  
J.N. BARROS ◽  
L.S. CUNHA ◽  
V.L.D. MASCARO ◽  
A.L. HOFLING-LIMA ◽  
...  

Técnica de exame de citologia de impressão foi padronizada em olhos de cães sem alterações oculares. Foram realizados exames de citologia de impressão do epitélio corneano, conjuntival e tarsal em 30 olhos de 21 animais de raças e idades variadas. As amostras foram colhidas de cães atendidos no Hospital Veterinário da FMVZ-USP entre fevereiro e julho de 2003, sendo coradas e avaliadas no Laboratório de Doenças Externas Oculares da UNIFESP. A colheita foi bem tolerada pelos cães e o papel filtro utilizado removeu células em quantidade e morfologia adequadas para estudo citológico. Foi observado em 100% dos casos que o epitélio da conjuntiva bulbar canina apresenta aspecto “metaplasia-like”, com ausência de células caliciformes. Estas só foram encontradas na conjuntiva tarsal em 21,4% das amostras avaliadas dessa região. A citologia de impressão é um método factível para avaliação da superfície ocular em cães. Entretanto, a celularidade das amostras obtidas do tarso mostrou-se inadequada. Além disso, a pesquisa da densidade de células caliciformes em áreas bulbares, embora usada em seres humanos, pode não servir como indicador de alteração da superfície ocular para a espécie canina. Standardization of canine ocular surface impression cytology Abstract Impression cytology technique in dog eyes without ocular disease was standardized. Impression cytology was performed in corneal, conjunctival and tarsal epithelium in 30 eyes of 21 animals with different races and ages. Samples were obtained from dogs attended in FMVZ-USP Veterinary Hospital between February to July 2003, being stained and evaluated at UNIFESP´s External Eye Disease Laboratory. Sampling was well tolerated by dogs and the filter paper used removed cells with adequate morphology and quantity for cytologyc evaluation. In all cases canine bulbar conjunctival epithelium showed metaplasia-like features without goblet cells. Impression cytology is a feasible method for ocular surface evaluation in dogs. However, celularity was considered inadequated in samples obtained from tarsal conjunctiva. Furthermore, seeking goblet cell density in bulbar areas, although used in human beings, may not be used as an ocular surface disease indicator in canine species.


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