Association between body composition and pulmonary function tests among health care workers in Iran

2021 ◽  
Vol 17 ◽  
Author(s):  
Hamidreza Pouragha ◽  
Hosein Kazemi ◽  
Gholamreza Pouryaghoub ◽  
Ramin Mehrdad
Keyword(s):  
Body Composition ◽  
Lung Function ◽  
Pulmonary Function ◽  
Visceral Fat ◽  
Pulmonary Function Tests ◽  
The Body ◽  
Fat Free Mass ◽  
The Other ◽  
Cross Sectional ◽  
Function Tests

Background: Why is bodyweight not a predictor of lung function, while height, sex, race, and age are predictors of lung capacity and function? In this study, we want to investigate the association between body composition and pulmonary function. And, as much as possible, answer the question of why bodyweight is not predictive of lung function. Methods: This cross-sectional study was performed among 2967 employees of Tehran University of Medical Sciences (TUMS) who participated in the TUMS Employees Cohort (TEC) study. The body composition of the participants was measured using the Bioelectrical Impedance Analysis (BIA) method. Anthropometric variables were also measured as a confounder. The pulmonary function of participants was assessed by a forced spirometry test. Results: The correlation of BIA values including fat-free mass and total body water with a pulmonary function such as FEV1, FVC, and FEF25-75 is higher than most anthropometric values such as weight, wrist circumference, and the waist to hip ratio. Also, in regression analysis, age and sex had an association with pulmonary function, but the weight did not show a significant relationship. On the other hand, fat-free mass and visceral fat were significantly associated with pulmonary function. One is direct and the other is inverse. Conclusion: We observed a negative association between visceral fat and pulmonary function tests and a direct association between Fat-free mass pulmonary function tests (FEV1 and FVC) adjusted for age, sex, and anthropometric indices.

Association Between Body Composition with Pulmonary Function Tests

2020 ◽  
Author(s):  
Hamidreza Pouragha ◽  
Hosein Kazemi ◽  
Gholamreza Pouryaghoub ◽  
Ramin Mehrdad
Keyword(s):  
Body Composition ◽  
Pulmonary Function ◽  
Visceral Fat ◽  
Pulmonary Function Tests ◽  
Bioelectrical Impedance ◽  
The Body ◽  
Fat Free Mass ◽  
The Other ◽  
Inverse Association ◽  
Cross Sectional

Abstract Background: Why is bodyweight not a predictor of lung function, however, height, sex, race, and age are predictors of lung capacity and function. In this study, we want to investigate the association between body composition and pulmonary function. And as much as possible, answer the question of why bodyweight is not predictive of lung function.Method: This cross-sectional study was performed among 2967 employees of Tehran University of Medical Sciences (TUMS) who participated in the TUMS Employees Cohort (TEC) study. The body composition of the participants was measured using the Bioelectrical Impedance Analysis (BIA) method. Anthropometric variables were also measured as a confounder. The pulmonary function of participants was assessed by a forced spirometry test.Results: The correlation of BIA values including fat-free mass and total body water with a pulmonary function such as FEV1, FVC, and FEF25-75 is higher than most anthropometric values such as weight, wrist circumference, and the waist to hip ratio. Also, in regression analysis, age and sex had an association with pulmonary function, but the weight did not show a significant relationship. On the other hand, fat-free mass and visceral fat were significantly associated with pulmonary function. One is direct and the other is inverse.Conclusion: The hypothesis that the results of this study created in the minds of the authors were that; The direct association of fat-free mass with pulmonary function may be ineffective by the inverse association of visceral fat with pulmonary function, leading to a lack of association between weight and pulmonary function.

“A COMPARATIVE STUDY OF LUNG FUNCTION TESTS IN SWIMMERS AND NORMAL INDIVIDUALS”

2021 ◽  
pp. 31-33
Author(s):  
Shaik Auliya Parveen ◽  
P. Nanda Kumar ◽  
B.V.K. Vijayalakshmi
Keyword(s):  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Total Sample ◽  
Cross Sectional Study ◽  
The Body ◽  
Swimming Pool ◽  
Upper Body ◽  
Cross Sectional ◽  
Function Tests ◽  
Disease Hospital

Introduction: Our human body is an amazing machine, in which perfectly coordinated events will occur simultaneously. Swimming is a sport which is suitable for people of many different ages, and tness levels. Regular swimming produces many changes in the body. It benets the upper body, torso and legs together and it will improve general strength, lung capacity, stamina and cardiovascular tness. Swimming is an aerobic exercise and it has a signicant effect on respiratory functions that helps the lungs to use oxygen efciently. Aim and objectives:Aim of the present study is to compare the Pulmonary Function Tests of swimmers and non-swimmers and to know whether swimming brings any changes in the pulmonary function tests .Materials and Methods: The present study is a cross sectional study .The total sample size is 100. Swimmers (subjects) are 50 and non-swimmers (controls) are 50 in number. Swimmers are selected from N.T.R.Stadium Swimming Pool, Guntur and Guntur Club Swimming pool, Guntur. Hundred subjects were screened for the study and 50 were selected as subjects. The Pulmonary Function Tests was conducted in the Infectious Disease Hospital, Guntur. Summary and Conclusion: In our study, there is a signicant increase in pulmonary function tests in swimmers compared to non – swimmers.

scholarly journals Predicting Pulmonary Function Testing from Quantified Computed Tomography Using Machine Learning Algorithms in Patients with COPD

Diagnostics ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 33 ◽  
Author(s):  
Joshua Gawlitza ◽  
Timo Sturm ◽  
Kai Spohrer ◽  
Thomas Henzler ◽  
Ibrahim Akin ◽  
...  
Keyword(s):  
Machine Learning ◽  
Computed Tomography ◽  
Lung Function ◽  
Pulmonary Function ◽  
Polynomial Regression ◽  
Pulmonary Function Tests ◽  
Quantitative Computed Tomography ◽  
Machine Learning Algorithms ◽  
Gradient Boosting ◽  
Function Tests

Introduction: Quantitative computed tomography (qCT) is an emergent technique for diagnostics and research in patients with chronic obstructive pulmonary disease (COPD). qCT parameters demonstrate a correlation with pulmonary function tests and symptoms. However, qCT only provides anatomical, not functional, information. We evaluated five distinct, partial-machine learning-based mathematical models to predict lung function parameters from qCT values in comparison with pulmonary function tests. Methods: 75 patients with diagnosed COPD underwent body plethysmography and a dose-optimized qCT examination on a third-generation, dual-source CT with inspiration and expiration. Delta values (inspiration—expiration) were calculated afterwards. Four parameters were quantified: mean lung density, lung volume low-attenuated volume, and full width at half maximum. Five models were evaluated for best prediction: average prediction, median prediction, k-nearest neighbours (kNN), gradient boosting, and multilayer perceptron. Results: The lowest mean relative error (MRE) was calculated for the kNN model with 16%. Similar low MREs were found for polynomial regression as well as gradient boosting-based prediction. Other models led to higher MREs and thereby worse predictive performance. Beyond the sole MRE, distinct differences in prediction performance, dependent on the initial dataset (expiration, inspiration, delta), were found. Conclusion: Different, partially machine learning-based models allow the prediction of lung function values from static qCT parameters within a reasonable margin of error. Therefore, qCT parameters may contain more information than we currently utilize and can potentially augment standard functional lung testing.

Composição Corporal de Adultos Com Síndrome de Down e Excesso de Peso Atendidos em Hospital Universitário

2018 ◽  
Vol 22 (1) ◽  
pp. 47
Author(s):  
Leiliane Cruz Reis ◽  
Livia Maria Machado Nunes ◽  
Maria Edilma Da Silva Bezerra ◽  
Rosilene Reis Della Noce
Keyword(s):  
Body Composition ◽  
Down Syndrome ◽  
Overweight And Obesity ◽  
The Body ◽  
Fat Free Mass ◽  
University Hospital ◽  
Normal Range ◽  
Cross Sectional ◽  
The Mean ◽  
The City

Pessoas com Síndrome de Down podem, frequentemente, apresentar doença cardíaca congênita, hipotireoidismo, distúrbios gastrointestinais e tendência ao sobrepeso e obesidade, comprometendo gravemente a saúde. O objetivo deste trabalho foi descrever a composição corporal de adultos com Síndrome de Down - SD e excesso de peso, atendidos em um Hospital Universitário. Trata-se de um estudo transversal e descritivo realizado na cidade de Belém do Pará, no ano de 2017, onde os participantes com SD, foram avaliados para determinação da composição corporal com a utilização do aparelho de bioimpedância elétrica InBody230. Foram avaliados 13 indivíduos de ambos os sexos com idades variando entre 20 e 40 anos. A média de peso dos indivíduos do sexo masculino e feminino foi de 71,8 kg e 69,2 kg respectivamente, a média de Índice de Massa Corporal - IMC foi de 31,27 kg/m² para os homens e 34,08 kg/m² para as mulheres, classificada em obesidade. A maioria dos indivíduos apresenta Massa Muscular Esquelética - MME e Massa Livre de Gordura - MLG dentro da faixa de normalidade, porém os valores de Massa de Gordura (MG), assim como a Relação Cintura Quadril - RCQ de todos os indivíduos estão elevados. O acompanhamento individualizado da composição corporal, por meio da bioimpedância elétrica, mostrou ser um instrumento eficaz para avaliação do estado nutricional dessa população.Palavras-chave: Síndrome de Down. Composição Corporal. Bioimpedância Elétrica.AbstractPeople with Down Syndrome can often have congenital heart disease, hypothyroidism, gastrointestinal disorders, and tendency to overweight and obesity severely compromising health. The objective of this study was to describe the body composition in adults with Down Syndrome and overweight treated in a University Hospital. This is a cross-sectional and descriptive study carried out in the city of Belém do Pará in 2017, where the participants with DS, were evaluated to determine the body composition with the use of InBody 230 electric bioimpedance device. Eight individuals of both sexes with ages varying between 20 and 40 years were evaluated. The mean weight of the male and female subjects was 71.8 kg and 69.2 kg respectively, the mean Body Mass Index (BMI) was 31.27 kg / m² for men and 34.08 kg / m² for women, classified as obesity. The majority of individuals had a Skeletal Muscle Mass (MME) and Fat Free Mass (MLG) within the normal range, but the values of Mass of Fat (MG), as well as the Hip Waist Ratio (WHR) of all individuals are high. The individualized monitoring of body composition through electric bioimpedance proved to be an effective tool for assessing the nutritional status of this population.Keywords: Down Syndrome. Body composition. Electric impedance.

A cohort study using pulmonary function tests and x-ray examination in toner-handling workers

2014 ◽  
Vol 34 (4) ◽  
pp. 345-356 ◽  
Author(s):  
H Kitamura ◽  
N Terunuma ◽  
S Kurosaki ◽  
K Hata ◽  
M Masuda ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Health Effects ◽  
Pulmonary Function Tests ◽  
Personal Exposure ◽  
Working Environment ◽  
X Rays ◽  
Cross Sectional ◽  
X Ray ◽  
Function Tests ◽  
Chest X Ray

Objectives: This study uses pulmonary function tests and chest x-ray examinations to examine the relationship between toner-handling work and its health effects. Methods: The subjects were 1504 male workers in a Japanese toner and photocopier manufacturing company, in the age range from 19 to 50 years in 2003. Personal exposure measurements, pulmonary function tests, chest x-ray examinations, biomarker measurements, and a questionnaire about respiratory symptoms were conducted. The present study reports the results of pulmonary function tests and chest x-ray examinations conducted in the subjects, which includes a cross-sectional study on the toner handling and non-handling workers and a longitudinal study from 2003 to 2008. Results: Few significant findings were suspected to be caused by toner exposure found in pulmonary function indices in both the cross-sectional and longitudinal studies. Any obvious fibrotic findings in chest x-ray findings related to the toner exposure could not be found out. Conclusion: No evidence of adverse effects on pulmonary function indices and chest x-rays was present in the toner-handling workers as compared to the nonspecifically exposed workers. Although the toner exposure concentration is quite low in the current well-controlled working environment, even among the toner-handling workers, we would like to continue this study in the future to verify the toner exposure health effects.

scholarly journals Integrative genomic analysis in African American children with asthma finds 3 novel loci associated with lung function

2020 ◽  
Author(s):  
Pagé C. Goddard ◽  
Kevin L. Keys ◽  
Angel C.Y. Mak ◽  
Eunice Yujung Lee ◽  
Amy K. Liu ◽  
...  
Keyword(s):  
Lung Function ◽  
Pulmonary Function ◽  
Genome Wide Association Study ◽  
Mononuclear Cells ◽  
Pulmonary Function Tests ◽  
Genomic Analysis ◽  
Lung Fibroblasts ◽  
Admixture Mapping ◽  
Function Tests ◽  
Genes And Environment

AbstractBronchodilator drugs are commonly prescribed for treatment and management of obstructive lung function present with diseases such as asthma. Administration of bronchodilator medication can partially or fully restore lung function as measured by pulmonary function tests. The genetics of baseline lung function measures taken prior to bronchodilator medication has been extensively studied, and the genetics of the bronchodilator response itself has received some attention. However, few studies have focused on the genetics of post-bronchodilator lung function. To address this gap, we analyzed lung function phenotypes in 1,103 subjects from the Study of African Americans, Asthma, Genes, and Environment (SAGE), a pediatric asthma case-control cohort, using an integrative genomic analysis approach that combined genotype, locus-specific genetic ancestry, and functional annotation information. We integrated genome-wide association study (GWAS) results with an admixture mapping scan of three pulmonary function tests (FEV1, FVC, and FEV1/FVC) taken before and after albuterol bronchodilator administration on the same subjects, yielding six traits. We identified 18 GWAS loci, and 5 additional loci from admixture mapping, spanning several known and novel lung function candidate genes. Most loci identified via admixture mapping exhibited wide variation in minor allele frequency across genotyped global populations. Functional fine-mapping revealed an enrichment of epigenetic annotations from peripheral blood mononuclear cells, fetal lung tissue, and lung fibroblasts. Our results point to three novel potential genetic drivers of pre- and post-bronchodilator lung function: ADAMTS1, RAD54B, and EGLN3.

scholarly journals A Cross-Sectional Study of Nemaline Myopathy

Neurology ◽  
2021 ◽  
pp. 10.1212/WNL.0000000000011458
Author(s):  
Kimberly Amburgey ◽  
Meryl Acker ◽  
Samia Saeed ◽  
Reshma Amin ◽  
Alan H. Beggs ◽  
...  
Keyword(s):  
Pulmonary Function ◽  
Outcome Measures ◽  
Pulmonary Function Tests ◽  
Severe Disease ◽  
Nemaline Myopathy ◽  
Cross Sectional Study ◽  
Longitudinal Assessment ◽  
Sectional Study ◽  
Cross Sectional ◽  
Function Tests

Objective:Nemaline myopathy (NM) is a rare neuromuscular condition with clinical and genetic heterogeneity. To establish disease natural history, we performed a cross-sectional study of NM, complemented by longitudinal assessment and exploration of pilot outcome measures.Methods:Fifty-seven individuals with NM were recruited at two family workshops, including 16 examined at both time points. Subjects were evaluated by clinical history and physical examination. Functional outcome measures included the Motor Function Measure (MFM), pulmonary function tests (PFTs), myometry, goniometry, and bulbar assessments.Results:The most common clinical classification was “typical congenital” (54%), whereas 42% had more severe presentations. 58% of individuals needed mechanical support, with 26% requiring wheelchair, tracheostomy, and feeding tube. The MFM scale was performed in 44/57 participants and showed reduced scores in most with little floor/ceiling effect. Of the 27 individuals completing PFTs, abnormal values were observed in 65%. Lastly, bulbar function was abnormal in all patients examined, as determined using a novel outcome measure. Genotypes included mutations in ACTA1 (18), NEB (20), and TPM2 (2). Seventeen individuals were genetically unresolved. Patients with pathogenic ACTA1 and NEB variants were largely similar in clinical phenotype. Patients without genetic resolution had more severe disease.Conclusion:In all, we present a comprehensive cross-sectional study of NM. Our data identify significant disabilities and support a relatively stable disease course. We identify a need for further diagnostic investigation for the genetically unresolved group. Lastly, MFM, pulmonary function tests, and the slurp test were identified as promising outcome measures for future clinical trials.

scholarly journals Effects of exercise on pulmonary function tests: A comparative study between athletes and non-athletes in Nepalese settings

2017 ◽  
Vol 6 (1) ◽  
pp. 21
Author(s):  
N B Mahotra ◽  
T M Amatya ◽  
B SJB Rana ◽  
D Banstola
Keyword(s):  
Comparative Study ◽  
Pulmonary Function ◽  
Forced Vital Capacity ◽  
Vital Capacity ◽  
Pulmonary Function Tests ◽  
Institute Of Medicine ◽  
Cross Sectional ◽  
Pulmonary Functions ◽  
Inspiratory Muscles ◽  
Function Tests

<p> Due to regular exercises, athletes tend to have an increase in pulmonary functions when compared to non exercising individuals, especially when the exercise is strenuous. Intensity and severity of sports engaged in by the athletes determines the extent of strengthening of the inspiratory muscles with a resultant increase in the lung volumes and capacities. Pulmonary parameters like tidal volume and forced vital capacity are significantly higher in athletes than in non athletes. A cross sectional comparative study was carried out in national sports council, Tribhuvan army club and institute of medicine, Kathmandu, Nepal. The athletes were footballers from Tribhuvan army club and sprinters from national sports council. The non-athletes were medical students from the institute of medicine, Kathmandu. Data were collected after performing spirometry and mean values were compared between athletes and non-athletes. Pulmonary functions were assessed based on forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1) and peak expiratory flow rate (PEFR) expressed as percent predicted for the age, sex, height, weight and race. Spirometry was performed in 169 subjects, out of which 84 were athletes and 85 were non-athletes. Athletes had a significantly superior FVC (P =0.00) compared to non-athletes. FEV1 was also recorded significantly higher in athletes than in non-athletes (P=0.023). Athletes have better pulmonary function tests than non-athletes because exercise in athletes strengthens the muscles of respiration. </p>

Perceived stress and its relationship with the body composition of undergraduate students of a medical college in Nigeria.

2016 ◽  
Author(s):  
Ayoola Ibifubara Aiyegbusi ◽  
Sunday Rufus Akinbo ◽  
Oluwadamilola Bolarinwa Adebisi
Keyword(s):  
Body Composition ◽  
Muscle Mass ◽  
Undergraduate Students ◽  
Perceived Stress ◽  
Stress Level ◽  
Visceral Fat ◽  
Cross Sectional Study ◽  
The Body ◽  
Cross Sectional ◽  
Significant Relationships

Background: Stress among medical undergraduates has been reported to be on the increase with subsequent tendency towards obesity. However, the association between perceived stress and body composition has yet to be determined.Objective: This cross-sectional study was undertaken to determine the relationship between perceived stress and body composition among undergraduates of the College of Medicine, University of Lagos, Nigeria.Methods: Three hundred and twenty-nine apparently healthy undergraduates (165 males and 164 females) with ages between 17 to 35 years participated in the study. Physical characteristics such as weight, height, body mass index (BMI), and body composition indices were measured using standard procedures. Questionnaires were administered to assess the levels of perceived stress of the participants. The data were analyzed using mean, standard deviation and Spearman’s Correlation Coefficient analysis.Results: The mean stress level was low (27.33 ± 10.60). There were significant relationships between the body composition indices and perceived stress with visceral fat having the strongest relationship (p = 0.004) while BMI had the least correlation (p = 0.037). There were also significant relationships between age, gender and body composition indices. The percentage muscle mass, visceral fat, and body fat had significant relationships with the gender of the participants.Conclusion: Visceral fat, BMI, and percentage muscle mass increased with an increase in perceived stress level, and females had a lower level of perceived stress than males.

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