Enhancing the Alternative Cellular Energy (ACE) Pathway with KELEA Activated Water as Therapy for Infectious Diseases

2020 ◽  
Vol 20 ◽  
Author(s):  
W. John Martin
Keyword(s):  
Immune System ◽  
Kinetic Energy ◽  
Infectious Diseases ◽  
Modern Medicine ◽  
Chemical Energy ◽  
Electrostatic Attraction ◽  
Cellular Energy ◽  
Competitive Process ◽  
Environmental Force

: Many infectious diseases have yet to be conquered by modern medicine. This is generally attributed to both a failure of the immune system and the lack of an effective anti-microbial pharmaceutical. Infections can be regarded as a competitive process between the microbe and the host for cellular energy-generated resources. Cells obtain energy not only from the metabolism of food but also from the alternative cellular energy (ACE) pathway. This pathway utilizes an environmental force termed KELEA (kinetic energy limiting electrostatic attraction), which provides an added kinetic/chemical energy to the body’s fluids. The ACE pathway can be enhanced through the use of KELEA activated water, which is currently available under different names from several sources. Enhancing the body’s ACE pathway, including the use of a wearable waterceutical, provides a novel means of potentially increasing the body’s resistance against all infectious diseases.

Nutritional Recommendation for COVID-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 753-757
Author(s):  
Anagha Gulhane ◽  
Shamli Hiware
Keyword(s):  
Immune System ◽  
Global Health ◽  
Infectious Diseases ◽  
Immune Function ◽  
The Body ◽  
Health Issue ◽  
System Quality ◽  
Life Phase ◽  
Global Health Issue ◽  
Nutritional Recommendation

It is the most unreliable truth that anybody can get infected by the COVID-19, and nobody can escape from the danger of getting tainted by the virus. Yet, the line of hope is that anyone and everyone can boost their resistance, thus avoid the risk of getting affected by the illness. The immunity of humans pulls down as they grow older. If their immune system is robust, them falling sick is feeble. If their resistance is weak, them getting ill is sound. Several factors affect the immune system and its ability, including its nourishment. A two-way connection between nutrition, infection and immunity presents. Changes in one part will affect the others part in our body that's the nature's rule. Well defined immune system quality which is present between each life phase may influence the type, generality and the degree of infections. At the same time, low nutrition to the body will decrease the immune function and expose the body to the danger of getting infected by infectious diseases. Different quantity of micronutrients is required for increasing the immunity power of our body. Generally the vitamins A,C,D,E,B2,B6,B12, iron, zinc and selenium.The deficiencies of micronutrients are acknowledged as a global health issue, and also low nutrition makes it prone to establishes the infections in the body.

1+1 > 2: Integration of the Host-directed Traditional Chinese Medicine and the Virus-targeted Modern Medicine in Control of COVID-19

2020 ◽  
Vol 7 (2) ◽  
pp. 89-94
Author(s):  
Jianjun Sun
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Infectious Diseases ◽  
Modern Medicine ◽  
The World ◽  
Plausible Mechanism

The COVID-19 pandemic has caused millions of infections and hundreds of thousands deaths in the world. The pandemic is still ongoing and no specific antivirals have been found to control COVID-19. The integration of Traditional Chinese Medicine with supportive measures of Modern Medicine has reportedly played an important role in the control of COVID-19 in China. This review summarizes the evidence of TCM in the treatment of COVID-19 and discusses the plausible mechanism of TCM in control of COVID-19 and other viral infectious diseases.

scholarly journals On the modeling of the interaction between tumor growth and the immune system using some new fractional and fractional-fractal operators

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Behzad Ghanbari
Keyword(s):  
Immune System ◽  
Infectious Diseases ◽  
Tumor Growth ◽  
Computational Models ◽  
Recent Literature ◽  
Approximate Solutions ◽  
Biological Phenomena ◽  
Uniqueness Of The Solution ◽  
Biological Concepts ◽  
New Research

Abstract Humans are always exposed to the threat of infectious diseases. It has been proven that there is a direct link between the strength or weakness of the immune system and the spread of infectious diseases such as tuberculosis, hepatitis, AIDS, and Covid-19 as soon as the immune system has no the power to fight infections and infectious diseases. Moreover, it has been proven that mathematical modeling is a great tool to accurately describe complex biological phenomena. In the recent literature, we can easily find that these effective tools provide important contributions to our understanding and analysis of such problems such as tumor growth. This is indeed one of the main reasons for the need to study computational models of how the immune system interacts with other factors involved. To this end, in this paper, we present some new approximate solutions to a computational formulation that models the interaction between tumor growth and the immune system with several fractional and fractal operators. The operators used in this model are the Liouville–Caputo, Caputo–Fabrizio, and Atangana–Baleanu–Caputo in both fractional and fractal-fractional senses. The existence and uniqueness of the solution in each of these cases is also verified. To complete our analysis, we include numerous numerical simulations to show the behavior of tumors. These diagrams help us explain mathematical results and better describe related biological concepts. In many cases the approximate results obtained have a chaotic structure, which justifies the complexity of unpredictable and uncontrollable behavior of cancerous tumors. As a result, the newly implemented operators certainly open new research windows in further computational models arising in the modeling of different diseases. It is confirmed that similar problems in the field can be also be modeled by the approaches employed in this paper.

scholarly journals INTRODUCTION: Immune Relevant Animal Models: Opportunities and Challenges

ILAR Journal ◽  
2018 ◽  
Vol 59 (3) ◽  
pp. 209-210
Author(s):  
Gregers Jungersen ◽  
Jorge Piedrahita
Keyword(s):  
Immune System ◽  
T Cell ◽  
Animal Models ◽  
Infectious Diseases ◽  
Tissue Specific ◽  
Car T Cell ◽  
Car T ◽  
Preclinical Animal Models

Abstract Valid interpretation of preclinical animal models in immunology-related clinical challenges is important to solve outstanding clinical needs. Given the overall complexity of the immune system and both species- and tissue-specific immune peculiarities, the selection and design of appropriate immune-relevant animal models is, however, not following a straightforward path. The topics in this issue of the ILAR Journal provide assessments of immune-relevant animal models used in oncology, hematopoietic-, CAR-T cell- and xenotransplantation, adjuvants and infectious diseases, and immune privileged inflammation that are providing key insights into unmet human clinical needs.

scholarly journals The role of nutrition in strengthening immune system against newly emerging viral diseases: case of SARS-CoV-2

2020 ◽  
Vol 4 (7) ◽  
pp. 240-244
Author(s):  
Meghit Boumediene Khaled ◽  
Nada Benajiba
Keyword(s):  
Immune System ◽  
Infectious Diseases ◽  
Nutritional Status ◽  
Infected Individual ◽  
Emerging Infectious Diseases ◽  
The Body ◽  
Healthy Diet ◽  
World Health ◽  
Viral Diseases ◽  
Prevention Measures

The immune system is involved in the protection of host against environmental agents such as pathogenic micro-organisms (bacteria, fungi, and viruses) and chemicals, thereby preserving the integrity of the body. To preserve organism defense mechanisms, adequate nutritional status should be maintained with appropriate intakes of calories, vitamins, minerals and water that should be continuously provided by a healthy diet. The emergence of new infectious diseases with new pathogenic properties constitutes a serious health issue worldwide. Severe acute respiratory syndrome (SARS) represents one of the most recent emerging infectious diseases, caused by a novel coronavirus member called (SARS-CoV-2), identified in Wuhan, Hubei, China in December 2019, and recognized as pandemic by the World Health Organization (WHO). The nutritional status of each COVID-19-infected patient should be assessed prior undertaking treatments. Nutritional support should be the basis of management of any infected individual. However, prevention measures remain the first priority and strategy to develop throughout proper hygiene, healthy diet and staying home. Keywords: Nutrition, Immune system, Viral diseases, SARS-CoV-2.

scholarly journals Pathogenesis and Treatment of Cytokine Storm Induced by Infectious Diseases

2021 ◽  
Vol 22 (23) ◽  
pp. 13009
Author(s):  
Xi-Dian Tang ◽  
Tian-Tian Ji ◽  
Jia-Rui Dong ◽  
Hao Feng ◽  
Feng-Qiang Chen ◽  
...  
Keyword(s):  
Immune System ◽  
Infectious Diseases ◽  
Targeted Therapies ◽  
Tissue Damage ◽  
Systemic Infection ◽  
Therapeutic Strategies ◽  
Targeted Treatment ◽  
Cytokine Storm ◽  
Pathophysiological Mechanisms ◽  
Circulating Cytokines

Cytokine storm is a phenomenon characterized by strong elevated circulating cytokines that most often occur after an overreactive immune system is activated by an acute systemic infection. A variety of cells participate in cytokine storm induction and progression, with profiles of cytokines released during cytokine storm varying from disease to disease. This review focuses on pathophysiological mechanisms underlying cytokine storm induction and progression induced by pathogenic invasive infectious diseases. Strategies for targeted treatment of various types of infection-induced cytokine storms are described from both host and pathogen perspectives. In summary, current studies indicate that cytokine storm-targeted therapies can effectively alleviate tissue damage while promoting the clearance of invading pathogens. Based on this premise, “multi-omics” immune system profiling should facilitate the development of more effective therapeutic strategies to alleviate cytokine storms caused by various diseases.

Infectious Diseases

2019 ◽  
Author(s):  
Doug Fink
Keyword(s):  
Infectious Diseases ◽  
Modern Medicine ◽  
Emerging Infections ◽  
High Resource ◽  
The World ◽  
Causes Of Mortality ◽  
And Migration ◽  
Almost All ◽  
Global And Local ◽  
Immunomodulatory Therapies

Infectious diseases are global and local. They impact health and dis­ease in every country, but protean factors— cultural, geographical, and political— determine their particular local distribution. Every single patient is globally colonized by microorganisms, but singular behaviours, genetics and co- morbidities significantly determine what organisms cause disease in any individual. The practice of infectious diseases medi­cine necessarily demands an understanding of the person and the world in which they live. This chapter will emphasize the importance of context in assessing patients for infectious diseases. In terms of global mortality, communicable diseases remain the leading causes of mortality. Despite the evocative epithet of ‘infectious diseases’, these are not all caused by creatures that creep and crawl. Cosmopolitan diseases (i.e. universally distributed infections such as influenza or bac­terial pneumonia) represent a huge burden wherever medicine is prac­tised. However, it is important to note that in high- resource settings, infection imported by travel and migration is increasing. In particular, the international traffic of emerging infections, such as Zika virus, and anti-microbial resistance (AMR) are already major healthcare problems. As the world shrinks and the climate changes, the distribution of infectious diseases will continue to change. The threat of AMR no longer looms— it is a present and real danger. In the time it will take for disciples of this text to reach the end of their specialty training, AMR will account annually for more deaths than cancer. The delivery of almost all interventional, surgical, and immunomodulatory therapies depends on our ability to provide effective anti- microbial prophylaxis and rescue. The ability of organisms to adapt rapidly to novel iatrogenic selection pressures means that the treatment of human immunodeficiency virus (HIV), tuberculosis (TB), malaria, and manifold other pathogens will be compromised, not simply anti- bacterial agents. The future of modern medicine depends on the global healthcare community sharing both concern and responsibility. This chapter will include cases pertaining to the management of AMR.

scholarly journals Sexual dimorphism in immune function: The role of sex steroid hormones

2018 ◽  
Vol 51 ◽  
pp. 02007
Author(s):  
Anna Mihailova ◽  
Indrikis Krams
Keyword(s):  
Immune System ◽  
Sexual Dimorphism ◽  
Infectious Diseases ◽  
Immune Function ◽  
Steroid Hormones ◽  
Adaptive Immunity ◽  
Gonadal Hormones ◽  
Sex Steroid ◽  
Innate And Adaptive Immunity

There is evidence of the relation of sex steroid hormones and sexual dimorphism in immune system response to infectious diseases. The aim of this review was to identify the role of sex hormones in immune function and sexual dimorphism of immune reactions. Gonadal hormones together with the immune system play an important role in process of immune responses to the disease [1]. Estrogens, progesterone and testosterone have different impacts on immune cells and different gonadal hormones are of high importance for responses of innate and adaptive immunity [1, 2]. Estrogens mainly enhance immune function while testosterone has a suppressive role. Higher progesterone during pregnancy leads to autoimmune disease remission and an elevated susceptibility toward certain infectious diseases [2, 3, 4]. The intensity and prevalence of viral infections are typically higher in males, whereas disease outcome could be worse for females [5]. Sexual dimorphism of immune function is based on different concentrations of sex hormones in males and females and on a specific mediating role of these hormones in immune function and response along with differences in innate and adaptive immunity.

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